Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BCL2 1件: BCL2 💬 |
Venetoclax Venetoclax 💬 |
Venetoclax | 028 1件: 28 💬 💬 |
2 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Acalabrutinib Acalabrutinib 💬 |
Acalabrutinib | 046 2件: 46, 61 💬 💬 |
3 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Branebrutinib Branebrutinib 💬 |
Branebrutinib | 046 3件: 46, 49, 53 💬 💬 |
4 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Evobrutinib Evobrutinib 💬 |
Evobrutinib | 013 3件: 13, 46, 49 💬 💬 |
5 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Fenebrutinib Fenebrutinib 💬 |
Fenebrutinib | 013 1件: 13 💬 💬 |
6 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Ibrutinib Ibrutinib 💬 |
Ibrutinib | 028 3件: 28, 60, 61 💬 💬 |
7 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Orelabrutinib Orelabrutinib 💬 |
Orelabrutinib | 013 4件: 13, 49, 61, 63 💬 💬 |
8 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Remibrutinib Remibrutinib 💬 |
Remibrutinib | 013 2件: 13, 53 💬 💬 |
9 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
BTK 1件: BTK 💬 |
Zanubrutinib Zanubrutinib 💬 |
Zanubrutinib | 013 5件: 13, 63, 222, 300, 331 💬 💬 |
10 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40 1件: CD40 💬 |
Bleselumab Bleselumab 💬 |
Bleselumab | 222 1件: 222 💬 💬 |
11 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40 1件: CD40 💬 |
Iscalimab Iscalimab 💬 |
Iscalimab | 049 2件: 49, 53 💬 💬 |
12 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40 1件: CD40 💬 |
Ravagalimab Ravagalimab 💬 |
Ravagalimab | 053 2件: 53, 97 💬 💬 |
13 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
CD40LG 1件: CD40LG 💬 |
Toralizumab Toralizumab 💬 |
Toralizumab | 063 1件: 63 💬 💬 |
14 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Canakinumab Canakinumab 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 💬 |
15 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Gevokizumab Gevokizumab 💬 |
Gevokizumab | 041 4件: 41, 50, 56, 269 💬 💬 |
16 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬 |
Rilonacept Rilonacept 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 💬 |
17 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1B 2件: IL1B, TNF 💬 |
Pirfenidone Pirfenidone 💬 |
Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬 |
18 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
IL1R1 1件: IL1R1 💬 |
Anakinra Anakinra 💬 |
Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬 |
19 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK 1件: LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 2件: 51, 85 💬 💬 |
20 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LCK 1件: LCK 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 2件: 51, 85 💬 💬 |
21 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA 1件: LTA 💬 |
Pateclizumab Pateclizumab 💬 |
Pateclizumab | 046 1件: 46 💬 💬 |
22 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTA 2件: LTA, TNF 💬 |
Etanercept Etanercept 💬 |
Etanercept | 015 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬 💬 |
23 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
LTB 1件: LTB 💬 |
Baminercept Baminercept 💬 |
Baminercept | 013 4件: 13, 46, 53, 97 💬 💬 |
24 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
NFKB1 1件: NFKB1 💬 |
Iguratimod Iguratimod 💬 |
Iguratimod | 046 5件: 46, 51, 53, 271, 300 💬 💬 |
25 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PARP1 1件: PARP1 💬 |
Olaparib Olaparib 💬 |
Olaparib | 086 2件: 86, 285 💬 💬 |
26 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PRKCB 1件: PRKCB 💬 |
Enzastaurin Enzastaurin 💬 |
Enzastaurin | 168 1件: 168 💬 💬 |
27 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PRKCQ 1件: PRKCQ 💬 |
Sotrastaurin Sotrastaurin 💬 |
Sotrastaurin | 097 1件: 97 💬 💬 |
28 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Aceclofenac Aceclofenac 💬 |
Aceclofenac | 046 1件: 46 💬 💬 |
29 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Acetaminophen Acetaminophen 💬 |
Acetaminophen | 003 15件: 3 , 6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬 💬 |
30 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Aspirin Aspirin 💬 |
Acetylsalicylic acid | 013 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬 💬 |
31 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Celecoxib Celecoxib 💬 |
Celecoxib | 002 10件: 2 , 3 , 34, 46, 70, 89, 107, 161, 171, 271 💬 💬 |
32 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Diclofenac Diclofenac 💬 |
Diclofenac | 013 5件: 13, 34, 46, 78, 271 💬 💬 |
33 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Diflunisal Diflunisal 💬 |
Diflunisal | 028 1件: 28 💬 💬 |
34 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Etodolac Etodolac 💬 |
Etodolac | 046 1件: 46 💬 💬 |
35 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Etoricoxib Etoricoxib 💬 |
Etoricoxib | 046 2件: 46, 271 💬 💬 |
36 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Flurbiprofen Flurbiprofen 💬 |
Flurbiprofen | 013 3件: 13, 21, 46 💬 💬 |
37 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Ibuprofen Ibuprofen 💬 |
Ibuprofen | 013 7件: 13, 46, 65, 107, 113, 271, 299 💬 💬 |
38 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Indomethacin Indomethacin 💬 |
Indomethacin | 225 3件: 225, 271, 298 💬 💬 |
39 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Ketoprofen Ketoprofen 💬 |
Ketoprofen | 046 1件: 46 💬 💬 |
40 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Ketorolac Ketorolac 💬 |
Ketorolac | 070 2件: 70, 226 💬 💬 |
41 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Loxoprofen Loxoprofen 💬 |
Loxoprofen | 046 2件: 46, 271 💬 💬 |
42 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Lumiracoxib Lumiracoxib 💬 |
Lumiracoxib | 046 1件: 46 💬 💬 |
43 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Meloxicam Meloxicam 💬 |
Meloxicam | 046 4件: 46, 49, 271, 296 💬 💬 |
44 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Naproxen Naproxen 💬 |
Naproxen | 013 4件: 13, 46, 107, 271 💬 💬 |
45 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Nimesulide Nimesulide 💬 |
Nimesulide | 046 1件: 46 💬 💬 |
46 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Parecoxib Parecoxib 💬 |
Parecoxib | 046 2件: 46, 271 💬 💬 |
47 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Rofecoxib Rofecoxib 💬 |
Rofecoxib | 046 1件: 46 💬 💬 |
48 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Salsalate Salsalate 💬 |
Salsalate | 005 1件: 5 💬 💬 |
49 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Sulindac Sulindac 💬 |
Sulindac | 206 1件: 206 💬 💬 |
50 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Tolfenamic acid Tolfenamic acid 💬 |
Tolfenamic acid | 005 1件: 5 💬 💬 |
51 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
PTGS2 1件: PTGS2 💬 |
Valdecoxib Valdecoxib 💬 |
Valdecoxib | 046 1件: 46 💬 💬 |
52 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
RELA 1件: RELA 💬 |
Edasalonexent Edasalonexent 💬 |
Edasalonexent | 113 1件: 113 💬 💬 |
53 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
SYK 1件: SYK 💬 |
Fostamatinib Fostamatinib 💬 |
Fostamatinib | 046 4件: 46, 49, 61, 66 💬 💬 |
54 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Adalimumab Adalimumab 💬 |
Adalimumab | 019 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬 💬 |
55 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Certolizumab pegol Certolizumab pegol 💬 |
Certolizumab pegol | 037 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬 💬 |
56 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Golimumab Golimumab 💬 |
Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬 💬 |
57 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Infliximab Infliximab 💬 |
Infliximab | 035 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬 💬 |
58 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Lenalidomide Lenalidomide 💬 |
Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬 💬 |
59 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Ozoralizumab Ozoralizumab 💬 |
Ozoralizumab | 046 1件: 46 💬 💬 |
60 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Pegsunercept Pegsunercept 💬 |
Pegsunercept | 046 1件: 46 💬 💬 |
61 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Pomalidomide Pomalidomide 💬 |
Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬 💬 |
62 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬 |
Thalidomide Thalidomide 💬 |
Thalidomide | 002 20件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬 💬 |
63 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFRSF13C 1件: TNFRSF13C 💬 |
Ianalumab Ianalumab 💬 |
Ianalumab | 035 7件: 35, 46, 49, 53, 61, 63, 95 💬 💬 |
64 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF11 1件: TNFSF11 💬 |
Denosumab Denosumab 💬 |
Denosumab | 046 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬 💬 |
65 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Atacicept Atacicept 💬 |
Atacicept | 013 4件: 13, 46, 49, 66 💬 💬 |
66 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Belimumab Belimumab 💬 |
Belimumab | 011 13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬 💬 |
67 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Tabalumab Tabalumab 💬 |
Tabalumab | 046 2件: 46, 49 💬 💬 |
68 | NF-kappa B signaling pathway 💬 20 genes, 67 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬 |
Tibulizumab Tibulizumab 💬 |
Tibulizumab | 053 1件: 53 💬 💬 |