Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Transcriptional misregulation in cancer 💬
1件: CD40 💬 Bleselumab 💬 Bleselumab 1件: 222 💬 💬
2 Transcriptional misregulation in cancer 💬
1件: CD40 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬 💬
3 Transcriptional misregulation in cancer 💬
1件: CD40 💬 Ravagalimab 💬 Ravagalimab 2件: 53, 97 💬 💬
4 Transcriptional misregulation in cancer 💬
1件: CD86 💬 Abatacept 💬 Abatacept 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 💬
5 Transcriptional misregulation in cancer 💬
1件: CD86 💬 Belatacept 💬 Belatacept 1件: 46 💬 💬
6 Transcriptional misregulation in cancer 💬
3件: CSF1R, FLT1, FLT3 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬 💬
7 Transcriptional misregulation in cancer 💬
2件: CSF1R, FLT3 💬 Pexidartinib 💬 Pexidartinib 1件: 34 💬 💬
8 Transcriptional misregulation in cancer 💬
1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬 💬
9 Transcriptional misregulation in cancer 💬
1件: ELANE 💬 Sivelestat 💬 Sivelestat 3件: 13, 85, 96 💬 💬
10 Transcriptional misregulation in cancer 💬
1件: FLT1 💬 Axitinib 💬 Axitinib 1件: 34 💬 💬
11 Transcriptional misregulation in cancer 💬
1件: FLT1 💬 Cediranib 💬 Cediranib 1件: 34 💬 💬
12 Transcriptional misregulation in cancer 💬
1件: FLT1 💬 Nintedanib 💬 Nintedanib 5件: 51, 85, 89, 227, 228 💬 💬
13 Transcriptional misregulation in cancer 💬
1件: FLT3 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬 💬
14 Transcriptional misregulation in cancer 💬
1件: GRIA3 💬 Perampanel 💬 Perampanel 3件:  2 ,  6 , 144 💬 💬
15 Transcriptional misregulation in cancer 💬
1件: GRIA3 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬 💬
16 Transcriptional misregulation in cancer 💬
1件: GRIA3 💬 Talampanel 💬 Talampanel 2件:  2 ,  6  💬 💬
17 Transcriptional misregulation in cancer 💬
1件: GRIA3 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬 💬
18 Transcriptional misregulation in cancer 💬
2件: HDAC1, HDAC2 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬 💬
19 Transcriptional misregulation in cancer 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬 💬
20 Transcriptional misregulation in cancer 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬 💬
21 Transcriptional misregulation in cancer 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬 💬
22 Transcriptional misregulation in cancer 💬
1件: IL1R2 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 💬
23 Transcriptional misregulation in cancer 💬
1件: IL2RB 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬 💬
24 Transcriptional misregulation in cancer 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬 💬
25 Transcriptional misregulation in cancer 💬
1件: IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬 💬
26 Transcriptional misregulation in cancer 💬
1件: IL6 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬 💬
27 Transcriptional misregulation in cancer 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬 💬
28 Transcriptional misregulation in cancer 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬 💬
29 Transcriptional misregulation in cancer 💬
1件: ITGB7 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬 💬
30 Transcriptional misregulation in cancer 💬
1件: ITGB7 💬 Etrolizumab 💬 Etrolizumab 2件: 96, 97 💬 💬
31 Transcriptional misregulation in cancer 💬
1件: ITGB7 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬 💬
32 Transcriptional misregulation in cancer 💬
1件: MET 💬 Cabozantinib 💬 Cabozantinib 1件: 34 💬 💬
33 Transcriptional misregulation in cancer 💬
1件: MPO 💬 Verdiperstat 💬 Verdiperstat 3件:  2 , 17, 127 💬 💬
34 Transcriptional misregulation in cancer 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬 💬
35 Transcriptional misregulation in cancer 💬
1件: NGFR 💬 Cenegermin 💬 Cenegermin 2件: 53, 90 💬 💬
36 Transcriptional misregulation in cancer 💬
2件: PML, RARA 💬 Tretinoin 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬 💬
37 Transcriptional misregulation in cancer 💬
1件: PPARG 💬 Bocidelpar 💬 Bocidelpar 1件: 113 💬 💬
38 Transcriptional misregulation in cancer 💬
1件: PPARG 💬 Leriglitazone 💬 Leriglitazone 1件: 20 💬 💬
39 Transcriptional misregulation in cancer 💬
1件: PPARG 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 💬
40 Transcriptional misregulation in cancer 💬
1件: PPARG 💬 Rosiglitazone 💬 Rosiglitazone 5件: 46, 75, 97, 222, 265 💬 💬
41 Transcriptional misregulation in cancer 💬
1件: PPARG 💬 Seladelpar 💬 Seladelpar 2件: 93, 94 💬 💬
42 Transcriptional misregulation in cancer 💬
1件: RARA 💬 Fenretinide 💬 Fenretinide 1件: 299 💬 💬
43 Transcriptional misregulation in cancer 💬
1件: RARA 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬 💬
44 Transcriptional misregulation in cancer 💬
1件: RARA 💬 Tamibarotene 💬 Tamibarotene 2件: 26, 96 💬 💬
45 Transcriptional misregulation in cancer 💬
1件: RARA 💬 Vitamin A 💬 Vitamin A 3件: 13, 53, 90 💬 💬
46 Transcriptional misregulation in cancer 💬
4件: RARA, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬 💬
47 Transcriptional misregulation in cancer 💬
4件: RARA, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬 💬
48 Transcriptional misregulation in cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬 💬
49 Transcriptional misregulation in cancer 💬
3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬 💬