Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 cAMP signaling pathway 💬
2件: ADORA1, ADORA2A 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬
2 cAMP signaling pathway 💬
2件: ADORA1, ADORA2A 💬 Adenosine phosphate 💬 Adenosine phosphate 1件: 46 💬
3 cAMP signaling pathway 💬
8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
4 cAMP signaling pathway 💬
8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
5 cAMP signaling pathway 💬
8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
6 cAMP signaling pathway 💬
8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
7 cAMP signaling pathway 💬
8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
8 cGMP-PKG signaling pathway 💬
2件: ADORA1, ADORA3 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬
9 cGMP-PKG signaling pathway 💬
2件: ADORA1, ADORA3 💬 Adenosine phosphate 💬 Adenosine phosphate 1件: 46 💬
10 cGMP-PKG signaling pathway 💬
4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
11 cGMP-PKG signaling pathway 💬
4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
12 cGMP-PKG signaling pathway 💬
4件: ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
13 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
14 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
15 Morphine addiction 💬
1件: ADORA1 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬
16 Morphine addiction 💬
1件: ADORA1 💬 Adenosine phosphate 💬 Adenosine phosphate 1件: 46 💬
17 Morphine addiction 💬
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
18 Morphine addiction 💬
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
19 Morphine addiction 💬
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
20 Morphine addiction 💬
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
21 Morphine addiction 💬
9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
22 Neuroactive ligand-receptor interaction 💬
2件: ADORA1, ADORA2A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
23 Neuroactive ligand-receptor interaction 💬
2件: ADORA1, ADORA2A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
24 Neuroactive ligand-receptor interaction 💬
4件: ADORA1, ADORA2A, ADORA2B, ADORA3 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬
25 Neuroactive ligand-receptor interaction 💬
4件: ADORA1, ADORA2A, ADORA2B, ADORA3 💬 Adenosine phosphate 💬 Adenosine phosphate 1件: 46 💬
26 Neuroactive ligand-receptor interaction 💬
2件: ADORA1, ADORA2B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
27 Neuroactive ligand-receptor interaction 💬
2件: ADORA1, ADORA2B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
28 Neuroactive ligand-receptor interaction 💬
2件: ADORA1, ADORA2B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
29 Regulation of lipolysis in adipocytes 💬
1件: ADORA1 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬
30 Regulation of lipolysis in adipocytes 💬
1件: ADORA1 💬 Adenosine phosphate 💬 Adenosine phosphate 1件: 46 💬
31 Regulation of lipolysis in adipocytes 💬
2件: ADORA1, PDE3B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
32 Regulation of lipolysis in adipocytes 💬
2件: ADORA1, PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
33 Regulation of lipolysis in adipocytes 💬
2件: ADORA1, PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
34 Regulation of lipolysis in adipocytes 💬
2件: ADORA1, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
35 Regulation of lipolysis in adipocytes 💬
2件: ADORA1, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
36 Renin secretion 💬
1件: ADORA1 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬
37 Renin secretion 💬
1件: ADORA1 💬 Adenosine phosphate 💬 Adenosine phosphate 1件: 46 💬
38 Renin secretion 💬
6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
39 Renin secretion 💬
6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
40 Renin secretion 💬
6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
41 Renin secretion 💬
4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
42 Renin secretion 💬
4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
43 Sphingolipid signaling pathway 💬
1件: ADORA1 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
44 Sphingolipid signaling pathway 💬
1件: ADORA1 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
45 Sphingolipid signaling pathway 💬
1件: ADORA1 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
46 Sphingolipid signaling pathway 💬
1件: ADORA1 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
47 Sphingolipid signaling pathway 💬
1件: ADORA1 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
48 Sphingolipid signaling pathway 💬
2件: ADORA1, ADORA3 💬 Adenosine 💬 Adenosine 3件: 13, 58, 65 💬
49 Sphingolipid signaling pathway 💬
2件: ADORA1, ADORA3 💬 Adenosine phosphate 💬 Adenosine phosphate 1件: 46 💬