Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 cGMP-PKG signaling pathway 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 Methylergometrine 💬 Methylergometrine 1件: 280 💬
2 cGMP-PKG signaling pathway 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin 1件:  6  💬
3 cGMP-PKG signaling pathway 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
4 cGMP-PKG signaling pathway 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine 1件: 11 💬
5 cGMP-PKG signaling pathway 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine 3件: 46, 70, 96 💬
6 cGMP-PKG signaling pathway 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
7 cGMP-PKG signaling pathway 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine 1件: 17 💬
8 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Apraclonidine 💬 Apraclonidine 1件: 11 💬
9 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Brimonidine 💬 Brimonidine 2件: 13, 90 💬
10 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
11 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Clonidine 💬 Clonidine 4件:  6 , 65, 70, 78 💬
12 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Clozapine 💬 Clozapine 1件:  6  💬
13 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Dexmedetomidine 💬 Dexmedetomidine 14件:  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
14 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Guanabenz 💬 Guanabenz 2件:  2 , 13 💬
15 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Rilmenidine 💬 Rilmenidine 1件:  8  💬
16 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Tizanidine 💬 Tizanidine 1件: 13 💬
17 cGMP-PKG signaling pathway 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Yohimbine 💬 Yohimbine 1件:  6  💬
18 Neuroactive ligand-receptor interaction 💬
6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 Methylergometrine 💬 Methylergometrine 1件: 280 💬
19 Neuroactive ligand-receptor interaction 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Dipivefrin 💬 Dipivefrin 1件:  6  💬
20 Neuroactive ligand-receptor interaction 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Droxidopa 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
21 Neuroactive ligand-receptor interaction 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Ephedrine 💬 Ephedrine 1件: 11 💬
22 Neuroactive ligand-receptor interaction 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Epinephrine 💬 Epinephrine 3件: 46, 70, 96 💬
23 Neuroactive ligand-receptor interaction 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
24 Neuroactive ligand-receptor interaction 💬
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 💬 Pseudoephedrine 💬 Pseudoephedrine 1件: 17 💬
25 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Apraclonidine 💬 Apraclonidine 1件: 11 💬
26 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Brimonidine 💬 Brimonidine 2件: 13, 90 💬
27 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Clonidine 💬 Clonidine 4件:  6 , 65, 70, 78 💬
28 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Dexmedetomidine 💬 Dexmedetomidine 14件:  2 ,  4 ,  6 , 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
29 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Guanabenz 💬 Guanabenz 2件:  2 , 13 💬
30 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Rilmenidine 💬 Rilmenidine 1件:  8  💬
31 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Tizanidine 💬 Tizanidine 1件: 13 💬
32 Neuroactive ligand-receptor interaction 💬
3件: ADRA2A, ADRA2B, ADRA2C 💬 Yohimbine 💬 Yohimbine 1件:  6  💬
33 Neuroactive ligand-receptor interaction 💬
13件: ADRA2A, ADRA2B, ADRA2C, CHRM1, CHRM2, CHRM3, CHRM4, CHRM5, DRD2, HRH1, HTR2A, HTR2B, HTR2C 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
34 Neuroactive ligand-receptor interaction 💬
6件: ADRA2A, ADRA2B, ADRA2C, DRD4, HTR2A, HTR2C 💬 Clozapine 💬 Clozapine 1件:  6  💬