Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 2 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
BRAF 4件: BRAF, FLT3, KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 3 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 4 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 5 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 6 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 7 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 8 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 9 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 10 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
BRAF 4件: BRAF, FLT4, KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 11 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 12 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 13 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 14 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 15 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 16 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 17 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 18 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 19 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 20 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 21 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 22 | Cushing syndrome 💬 24 genes, 50 drugs (DrugBank) and 66 diseases |
BRAF 1件: BRAF 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 23 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 24 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF 4件: BRAF, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 25 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 26 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 27 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 28 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 29 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 30 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 31 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 32 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 33 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 34 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 35 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 36 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 37 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 38 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 39 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 40 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 41 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 42 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 43 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 44 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 45 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 46 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 47 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 48 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 49 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 50 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 51 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 52 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF 7件: BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 53 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 54 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 55 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 56 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 57 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 58 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 59 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 60 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 61 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 62 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF 3件: BRAF, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 63 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 64 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 65 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 66 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 67 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 68 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF 7件: BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 69 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 70 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 71 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 72 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 73 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 74 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 75 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 76 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF 3件: BRAF, KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 77 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 78 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
BRAF 6件: BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 79 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 80 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 81 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 82 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 83 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 84 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 85 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 86 | Thyroid cancer 💬 8 genes, 16 drugs (DrugBank) and 28 diseases |
BRAF 2件: BRAF, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 87 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
| 88 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|