Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adherens junction 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
2 Adherens junction 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
3 Adherens junction 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
4 AMPK signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
5 AMPK signaling pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
6 AMPK signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
7 Autophagy - animal 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
8 Autophagy - animal 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
9 Autophagy - animal 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
10 Breast cancer 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
11 Breast cancer 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
12 Breast cancer 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
13 EGFR tyrosine kinase inhibitor resistance 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
14 EGFR tyrosine kinase inhibitor resistance 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
15 EGFR tyrosine kinase inhibitor resistance 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
16 Endocrine resistance 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
17 Endocrine resistance 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
18 Endocrine resistance 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
19 Endocytosis 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
20 Endocytosis 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
21 Endocytosis 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
22 Focal adhesion 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
23 Focal adhesion 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
24 Focal adhesion 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
25 FoxO signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
26 FoxO signaling pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
27 FoxO signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
28 Glioma 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
29 Glioma 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
30 Glioma 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
31 Hepatocellular carcinoma 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
32 Hepatocellular carcinoma 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
33 Hepatocellular carcinoma 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
34 HIF-1 signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
35 HIF-1 signaling pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
36 HIF-1 signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
37 Long-term depression 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
38 Long-term depression 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
39 Long-term depression 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
40 Longevity regulating pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
41 Longevity regulating pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
42 Longevity regulating pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
43 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
44 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
45 Longevity regulating pathway - multiple species 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
46 MAPK signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
47 MAPK signaling pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
48 MAPK signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
49 Melanoma 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
50 Melanoma 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
51 Melanoma 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
52 mTOR signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
53 mTOR signaling pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
54 mTOR signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
55 Oocyte meiosis 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
56 Oocyte meiosis 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
57 Oocyte meiosis 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
58 Ovarian steroidogenesis 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
59 Ovarian steroidogenesis 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
60 Ovarian steroidogenesis 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
61 Pathways in cancer 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
62 Pathways in cancer 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
63 Pathways in cancer 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
64 PI3K-Akt signaling pathway 💬
2件: GHR, IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
65 PI3K-Akt signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
66 PI3K-Akt signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
67 Progesterone-mediated oocyte maturation 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
68 Progesterone-mediated oocyte maturation 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
69 Progesterone-mediated oocyte maturation 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
70 Prostate cancer 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
71 Prostate cancer 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
72 Prostate cancer 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
73 Proteoglycans in cancer 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
74 Proteoglycans in cancer 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
75 Proteoglycans in cancer 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
76 Rap1 signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
77 Rap1 signaling pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
78 Rap1 signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
79 Ras signaling pathway 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
80 Ras signaling pathway 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
81 Ras signaling pathway 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
82 Signaling pathways regulating pluripotency of stem cells 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
83 Signaling pathways regulating pluripotency of stem cells 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
84 Signaling pathways regulating pluripotency of stem cells 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬
85 Transcriptional misregulation in cancer 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
86 Transcriptional misregulation in cancer 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 6件: 65, 78, 96, 168, 265, 299 💬
87 Transcriptional misregulation in cancer 💬
1件: IGF1R 💬 Teprotumumab 💬 Teprotumumab 1件: 51 💬