Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 2 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 3 | AGE-RAGE signaling pathway in diabetic complications 💬 26 genes, 45 drugs (DrugBank) and 83 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 4 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 5 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 6 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 7 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 8 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 1件: IL1A 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 9 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 10 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
CCL2 6件: CCL2, IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 11 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 12 | Cytokine-cytokine receptor interaction 💬 81 genes, 114 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 13 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
CCL2 4件: CCL2, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 14 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 15 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 16 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 17 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 18 | Graft-versus-host disease 💬 7 genes, 22 drugs (DrugBank) and 60 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 19 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 20 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 21 | Hematopoietic cell lineage 💬 32 genes, 70 drugs (DrugBank) and 90 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 22 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 23 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 24 | Inflammatory bowel disease 💬 24 genes, 43 drugs (DrugBank) and 64 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 25 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 26 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 27 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 28 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL10 4件: IL10, IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 29 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 30 | Leishmaniasis 💬 25 genes, 63 drugs (DrugBank) and 93 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 31 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 32 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 33 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 34 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 35 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 36 | Measles 💬 40 genes, 44 drugs (DrugBank) and 52 diseases |
IL1A 3件: IL1A, IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 37 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 38 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 39 | Necroptosis 💬 28 genes, 39 drugs (DrugBank) and 68 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 40 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 41 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 42 | Non-alcoholic fatty liver disease 💬 23 genes, 47 drugs (DrugBank) and 86 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 43 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 44 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 45 | Osteoclast differentiation 💬 36 genes, 71 drugs (DrugBank) and 93 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 46 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 47 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 48 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 49 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 50 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 51 | Pertussis 💬 18 genes, 38 drugs (DrugBank) and 66 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 52 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 53 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 54 | Prion disease 💬 41 genes, 66 drugs (DrugBank) and 107 diseases |
IL1A 4件: IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 55 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 56 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 57 | Rheumatoid arthritis 💬 22 genes, 49 drugs (DrugBank) and 74 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 58 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL10 5件: IL10, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 59 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 60 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 61 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 62 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 63 | Type I diabetes mellitus 💬 11 genes, 22 drugs (DrugBank) and 68 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|