Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
EGFR 4件: EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 2 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FGFR1 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 3 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 4 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 5 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT1 6件: FLT1, FLT4, KDR, PDGFRA, PDGFRB, RET 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 6 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
FLT4 4件: FLT4, KDR, PDGFRB, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 7 | Calcium signaling pathway 💬 79 genes, 187 drugs (DrugBank) and 134 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 8 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
AXL 3件: AXL, KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 9 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF 4件: BRAF, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 10 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
EGFR 3件: EGFR, ERBB2, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 11 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
FGFR2 5件: FGFR2, FGFR3, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 12 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR 1件: KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 13 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR 1件: KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 14 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
KDR 3件: KDR, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 15 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR 1件: KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 16 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR 1件: KDR 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 17 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR 1件: KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 18 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR 1件: KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 19 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR 1件: KDR 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 20 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR 1件: KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 21 | Fluid shear stress and atherosclerosis 💬 29 genes, 48 drugs (DrugBank) and 86 diseases |
KDR 1件: KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 22 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 23 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
EGFR 4件: EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 24 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 25 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 26 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 27 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
FLT1 5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 28 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 29 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF 7件: BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 30 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
CSF1R 8件: CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 31 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
EGFR 4件: EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 32 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FGFR1 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 33 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 34 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 35 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 36 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
CSF1R 8件: CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 37 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
EGFR 4件: EGFR, ERBB2, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 38 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FGFR1 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 39 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 40 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 41 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT3 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 42 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 43 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF 3件: BRAF, KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 44 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
EGFR 3件: EGFR, ERBB2, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 45 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
FGFR1 2件: FGFR1, KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 46 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR 1件: KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 47 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR 1件: KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 48 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR 1件: KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 49 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 50 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
BRAF 6件: BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 51 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
CSF1R 7件: CSF1R, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 52 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
EGFR 3件: EGFR, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 53 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FGFR1 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 54 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 55 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 56 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 57 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
CSF1R 8件: CSF1R, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 58 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
EGFR 3件: EGFR, FLT4, KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 59 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FGFR1 8件: FGFR1, FGFR2, FGFR3, FLT1, FLT4, KDR, PDGFRA, PDGFRB 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 60 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 61 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT1 3件: FLT1, FLT4, KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 62 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT3 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 63 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
KDR 2件: KDR, MET 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 64 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 1件: KDR 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 65 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 1件: KDR 💬
|
Cabozantinib Cabozantinib 💬
| Cabozantinib | 034 1件: 34 💬
|
| 66 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 1件: KDR 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 67 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 1件: KDR 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 5件: 51, 85, 89, 227, 228 💬
|
| 68 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 1件: KDR 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 69 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 1件: KDR 💬
|
Tesevatinib Tesevatinib 💬
| Tesevatinib | 067 1件: 67 💬
|
| 70 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 2件: KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|