Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
2 cGMP-PKG signaling pathway 💬
5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
3 cGMP-PKG signaling pathway 💬
1件: PDE5A 💬 Dipyridamole 💬 Dipyridamole 6件: 46, 49, 51, 66, 96, 224 💬
4 cGMP-PKG signaling pathway 💬
1件: PDE5A 💬 Sildenafil 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
5 cGMP-PKG signaling pathway 💬
1件: PDE5A 💬 Tadalafil 💬 Tadalafil 7件:  6 , 51, 75, 84, 86, 113, 210 💬
6 cGMP-PKG signaling pathway 💬
1件: PDE5A 💬 Udenafil 💬 Udenafil 2件: 86, 210 💬
7 cGMP-PKG signaling pathway 💬
1件: PDE5A 💬 Vardenafil 💬 Vardenafil 3件: 13, 86, 299 💬
8 Metabolic pathways 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
9 Metabolic pathways 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
10 Metabolic pathways 💬
2件: PDE4A, PDE5A 💬 Dipyridamole 💬 Dipyridamole 6件: 46, 49, 51, 66, 96, 224 💬
11 Metabolic pathways 💬
1件: PDE5A 💬 Sildenafil 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
12 Metabolic pathways 💬
1件: PDE5A 💬 Tadalafil 💬 Tadalafil 7件:  6 , 51, 75, 84, 86, 113, 210 💬
13 Metabolic pathways 💬
1件: PDE5A 💬 Udenafil 💬 Udenafil 2件: 86, 210 💬
14 Metabolic pathways 💬
1件: PDE5A 💬 Vardenafil 💬 Vardenafil 3件: 13, 86, 299 💬
15 Purine metabolism 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
16 Purine metabolism 💬
9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 21, 46, 78, 96, 97, 265 💬
17 Purine metabolism 💬
2件: PDE4A, PDE5A 💬 Dipyridamole 💬 Dipyridamole 6件: 46, 49, 51, 66, 96, 224 💬
18 Purine metabolism 💬
1件: PDE5A 💬 Sildenafil 💬 Sildenafil 17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
19 Purine metabolism 💬
1件: PDE5A 💬 Tadalafil 💬 Tadalafil 7件:  6 , 51, 75, 84, 86, 113, 210 💬
20 Purine metabolism 💬
1件: PDE5A 💬 Udenafil 💬 Udenafil 2件: 86, 210 💬
21 Purine metabolism 💬
1件: PDE5A 💬 Vardenafil 💬 Vardenafil 3件: 13, 86, 299 💬