Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Acute myeloid leukemia 💬 17 genes, 30 drugs (DrugBank) and 62 diseases |
BRAF 4件: BRAF, FLT3, KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 2 | Alcoholism 💬 28 genes, 75 drugs (DrugBank) and 53 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 3 | Alzheimer disease 💬 55 genes, 116 drugs (DrugBank) and 122 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 4 | Apelin signaling pathway 💬 12 genes, 30 drugs (DrugBank) and 72 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 5 | Apoptosis 💬 16 genes, 28 drugs (DrugBank) and 59 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 6 | Autophagy - animal 💬 13 genes, 18 drugs (DrugBank) and 62 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 7 | Axon guidance 💬 20 genes, 21 drugs (DrugBank) and 70 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 8 | B cell receptor signaling pathway 💬 19 genes, 29 drugs (DrugBank) and 68 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 9 | Bladder cancer 💬 10 genes, 23 drugs (DrugBank) and 22 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 10 | Breast cancer 💬 21 genes, 60 drugs (DrugBank) and 74 diseases |
BRAF 4件: BRAF, FLT4, KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 11 | C-type lectin receptor signaling pathway 💬 26 genes, 64 drugs (DrugBank) and 99 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 12 | cAMP signaling pathway 💬 67 genes, 171 drugs (DrugBank) and 114 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 13 | Cellular senescence 💬 26 genes, 40 drugs (DrugBank) and 92 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 14 | Central carbon metabolism in cancer 💬 18 genes, 29 drugs (DrugBank) and 56 diseases |
FLT3 5件: FLT3, KIT, PDGFRB, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 15 | cGMP-PKG signaling pathway 💬 46 genes, 119 drugs (DrugBank) and 118 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 16 | Chemical carcinogenesis - reactive oxygen species 💬 25 genes, 37 drugs (DrugBank) and 42 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 17 | Chemical carcinogenesis - receptor activation 💬 39 genes, 126 drugs (DrugBank) and 116 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 18 | Chemokine signaling pathway 💬 22 genes, 29 drugs (DrugBank) and 51 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 19 | Choline metabolism in cancer 💬 11 genes, 25 drugs (DrugBank) and 53 diseases |
PDGFRB 2件: PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 20 | Chronic myeloid leukemia 💬 17 genes, 20 drugs (DrugBank) and 29 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 21 | Colorectal cancer 💬 14 genes, 23 drugs (DrugBank) and 49 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 22 | EGFR tyrosine kinase inhibitor resistance 💬 26 genes, 56 drugs (DrugBank) and 83 diseases |
BRAF 4件: BRAF, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 23 | Endocrine resistance 💬 20 genes, 43 drugs (DrugBank) and 62 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 24 | Endometrial cancer 💬 10 genes, 18 drugs (DrugBank) and 20 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 25 | ErbB signaling pathway 💬 14 genes, 26 drugs (DrugBank) and 53 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 26 | Estrogen signaling pathway 💬 19 genes, 74 drugs (DrugBank) and 64 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 27 | Fc epsilon RI signaling pathway 💬 20 genes, 42 drugs (DrugBank) and 62 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 28 | Fc gamma R-mediated phagocytosis 💬 9 genes, 12 drugs (DrugBank) and 15 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 29 | Focal adhesion 💬 27 genes, 43 drugs (DrugBank) and 44 diseases |
BRAF 5件: BRAF, FLT4, KDR, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 30 | FoxO signaling pathway 💬 24 genes, 40 drugs (DrugBank) and 54 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 31 | Gap junction 💬 26 genes, 87 drugs (DrugBank) and 77 diseases |
PDGFRB 2件: PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 32 | Gastric cancer 💬 21 genes, 34 drugs (DrugBank) and 57 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 33 | Glioma 💬 15 genes, 30 drugs (DrugBank) and 57 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 34 | GnRH secretion 💬 20 genes, 42 drugs (DrugBank) and 54 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 35 | GnRH signaling pathway 💬 16 genes, 36 drugs (DrugBank) and 37 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 36 | Growth hormone synthesis, secretion and action 💬 24 genes, 41 drugs (DrugBank) and 76 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 37 | Hepatitis B 💬 41 genes, 54 drugs (DrugBank) and 73 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 38 | Hepatitis C 💬 34 genes, 59 drugs (DrugBank) and 72 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 39 | Hepatocellular carcinoma 💬 21 genes, 31 drugs (DrugBank) and 57 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 40 | Human cytomegalovirus infection 💬 56 genes, 104 drugs (DrugBank) and 120 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 41 | Human immunodeficiency virus 1 infection 💬 41 genes, 43 drugs (DrugBank) and 89 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 42 | Human papillomavirus infection 💬 40 genes, 91 drugs (DrugBank) and 105 diseases |
PDGFRB 2件: PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 43 | Influenza A 💬 45 genes, 63 drugs (DrugBank) and 85 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 44 | Insulin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 45 | JAK-STAT signaling pathway 💬 58 genes, 91 drugs (DrugBank) and 96 diseases |
PDGFRB 2件: PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 46 | Kaposi sarcoma-associated herpesvirus infection 💬 50 genes, 84 drugs (DrugBank) and 108 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 47 | Long-term depression 💬 13 genes, 19 drugs (DrugBank) and 32 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 48 | Long-term potentiation 💬 18 genes, 33 drugs (DrugBank) and 86 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 49 | MAPK signaling pathway 💬 61 genes, 85 drugs (DrugBank) and 110 diseases |
BRAF 7件: BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 50 | Melanogenesis 💬 7 genes, 16 drugs (DrugBank) and 29 diseases |
KIT 2件: KIT, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 51 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 52 | MicroRNAs in cancer 💬 31 genes, 65 drugs (DrugBank) and 85 diseases |
PDGFRB 2件: PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 53 | mTOR signaling pathway 💬 14 genes, 32 drugs (DrugBank) and 91 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 54 | Natural killer cell mediated cytotoxicity 💬 37 genes, 42 drugs (DrugBank) and 80 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 55 | Neurotrophin signaling pathway 💬 21 genes, 26 drugs (DrugBank) and 32 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 56 | Neutrophil extracellular trap formation 💬 35 genes, 36 drugs (DrugBank) and 61 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 57 | Non-small cell lung cancer 💬 21 genes, 33 drugs (DrugBank) and 45 diseases |
BRAF 3件: BRAF, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 58 | Oxytocin signaling pathway 💬 34 genes, 73 drugs (DrugBank) and 108 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 59 | Pancreatic cancer 💬 19 genes, 36 drugs (DrugBank) and 67 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 60 | Parathyroid hormone synthesis, secretion and action 💬 21 genes, 48 drugs (DrugBank) and 65 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 61 | Pathways in cancer 💬 104 genes, 194 drugs (DrugBank) and 133 diseases |
BRAF 7件: BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 62 | Pathways of neurodegeneration - multiple diseases 💬 59 genes, 120 drugs (DrugBank) and 125 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 63 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 34 genes, 51 drugs (DrugBank) and 92 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 64 | Phospholipase D signaling pathway 💬 23 genes, 51 drugs (DrugBank) and 76 diseases |
KIT 3件: KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 65 | PI3K-Akt signaling pathway 💬 76 genes, 112 drugs (DrugBank) and 112 diseases |
FLT3 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 66 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 42 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 67 | Prolactin signaling pathway 💬 19 genes, 39 drugs (DrugBank) and 54 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 68 | Prostate cancer 💬 22 genes, 51 drugs (DrugBank) and 80 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 69 | Proteoglycans in cancer 💬 30 genes, 68 drugs (DrugBank) and 96 diseases |
BRAF 3件: BRAF, KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 70 | Rap1 signaling pathway 💬 42 genes, 101 drugs (DrugBank) and 85 diseases |
BRAF 6件: BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 71 | Ras signaling pathway 💬 35 genes, 53 drugs (DrugBank) and 62 diseases |
FLT3 6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 72 | Regulation of actin cytoskeleton 💬 28 genes, 60 drugs (DrugBank) and 63 diseases |
BRAF 3件: BRAF, PDGFRB, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 73 | Relaxin signaling pathway 💬 19 genes, 30 drugs (DrugBank) and 38 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 74 | Renal cell carcinoma 💬 12 genes, 15 drugs (DrugBank) and 19 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 75 | Salmonella infection 💬 27 genes, 40 drugs (DrugBank) and 66 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 76 | Serotonergic synapse 💬 38 genes, 112 drugs (DrugBank) and 79 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 77 | Signaling pathways regulating pluripotency of stem cells 💬 19 genes, 28 drugs (DrugBank) and 48 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 78 | Sphingolipid signaling pathway 💬 30 genes, 52 drugs (DrugBank) and 73 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 79 | T cell receptor signaling pathway 💬 34 genes, 46 drugs (DrugBank) and 80 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 80 | Thyroid hormone signaling pathway 💬 24 genes, 41 drugs (DrugBank) and 67 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 81 | Tuberculosis 💬 49 genes, 65 drugs (DrugBank) and 91 diseases |
RAF1 1件: RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 82 | Vascular smooth muscle contraction 💬 31 genes, 77 drugs (DrugBank) and 68 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
| 83 | VEGF signaling pathway 💬 21 genes, 53 drugs (DrugBank) and 90 diseases |
KDR 2件: KDR, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|