Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRA1A 💬 Alfuzosin 💬 Alfuzosin 1件: 13 💬
2 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRA1A 💬 Silodosin 💬 Silodosin 2件:  6 , 13 💬
3 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Doxazosin 💬 Doxazosin 2件: 57, 67 💬
4 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Methylergometrine 💬 Methylergometrine 1件: 280 💬
5 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Midodrine 💬 Midodrine 3件:  6 , 17, 58 💬
6 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
7 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Phenylephrine 💬 Phenylephrine 1件: 22 💬
8 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Tamsulosin 💬 Tamsulosin 1件: 13 💬
9 Adrenergic signaling in cardiomyocytes 💬
 3件: ADRA1A, ADRA1B, ADRA1D 💬 Terazosin 💬 Terazosin 1件:  6  💬
10 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Carvedilol 💬 Carvedilol 4件: 57, 86, 113, 210 💬
11 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Dipivefrin 💬 Dipivefrin 1件:  6  💬
12 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Droxidopa 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
13 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Ephedrine 💬 Ephedrine 1件: 11 💬
14 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Epinephrine 💬 Epinephrine 3件: 46, 70, 96 💬
15 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
16 Adrenergic signaling in cardiomyocytes 💬
 5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬 Pseudoephedrine 💬 Pseudoephedrine 1件: 17 💬
17 Adrenergic signaling in cardiomyocytes 💬
 6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, KCNQ1, SCN5A 💬 Amiodarone 💬 Amiodarone 2件: 28, 127 💬
18 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Atenolol 💬 Atenolol 1件: 167 💬
19 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬
20 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Celiprolol 💬 Celiprolol 1件: 168 💬
21 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬
22 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Esmolol 💬 Esmolol 1件: 58 💬
23 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Metoprolol 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
24 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB1 💬 Nebivolol 💬 Nebivolol 4件: 17, 85, 113, 167 💬
25 Adrenergic signaling in cardiomyocytes 💬
 2件: ADRB1, ADRB2 💬 Nadolol 💬 Nadolol 1件:  6  💬
26 Adrenergic signaling in cardiomyocytes 💬
 2件: ADRB1, ADRB2 💬 Propranolol 💬 Propranolol 6件:  6 , 158, 167, 227, 278, 296 💬
27 Adrenergic signaling in cardiomyocytes 💬
 2件: ADRB1, ADRB2 💬 Timolol 💬 Timolol 2件: 157, 227 💬
28 Adrenergic signaling in cardiomyocytes 💬
 2件: ADRB1, ADRB2 💬 Timolol 💬 Timolol 2件: 157, 227 💬
29 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Clenbuterol 💬 Clenbuterol 5件:  1 ,  2 ,  6 , 13, 256 💬
30 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Formoterol 💬 Formoterol 3件: 85, 228, 299 💬
31 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Isoxsuprine 💬 Isoxsuprine 1件: 13 💬
32 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Levosalbutamol 💬 Levosalbutamol 1件: 49 💬
33 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Albuterol 💬 Salbutamol 12件:  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
34 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Salmeterol 💬 Salmeterol 1件: 299 💬
35 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Terbutaline 💬 Terbutaline 1件: 118 💬
36 Adrenergic signaling in cardiomyocytes 💬
 1件: ADRB2 💬 Tulobuterol 💬 Tulobuterol 1件:  6  💬
37 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬
38 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 Candesartan cilexetil 💬 Candesartan cilexetil 1件: 67 💬
39 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬
40 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 Losartan 💬 Losartan 17件: 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
41 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬
42 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬
43 Adrenergic signaling in cardiomyocytes 💬
 1件: AGTR1 💬 Valsartan 💬 Valsartan 7件: 57, 58, 66, 75, 218, 222, 224 💬
44 Adrenergic signaling in cardiomyocytes 💬
 2件: AGTR1, AGTR2 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
45 Adrenergic signaling in cardiomyocytes 💬
 2件: AGTR1, AGTR2 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 19, 46, 66, 86, 222, 224 💬
46 Adrenergic signaling in cardiomyocytes 💬
 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin 1件: 299 💬
47 Adrenergic signaling in cardiomyocytes 💬
 4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digoxin 💬 Digoxin 3件:  8 , 46, 210 💬
48 Adrenergic signaling in cardiomyocytes 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 1件: 28 💬
49 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 4件: 13, 51, 67, 298 💬
50 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
51 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 3件: 51, 58, 86 💬
52 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬
53 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
54 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 2件: 50, 81 💬
55 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
56 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
57 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬
58 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
59 Adrenergic signaling in cardiomyocytes 💬
 5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 Topiramate 💬 Topiramate 6件:  6 , 97, 140, 144, 156, 193 💬
60 Adrenergic signaling in cardiomyocytes 💬
 2件: CACNA2D1, CACNA2D2 💬 Mirogabalin 💬 Mirogabalin 1件: 70 💬
61 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
62 Adrenergic signaling in cardiomyocytes 💬
 4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬
63 Adrenergic signaling in cardiomyocytes 💬
 1件: KCNQ1 💬 Ezogabine 💬 Ezogabine 2件:  2 , 144 💬
64 Adrenergic signaling in cardiomyocytes 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
65 Adrenergic signaling in cardiomyocytes 💬
 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
66 Adrenergic signaling in cardiomyocytes 💬
 1件: MYH7 💬 Mavacamten 💬 Mavacamten 1件: 58 💬
67 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Bupivacaine 💬 Bupivacaine 8件: 46, 51, 53, 70, 96, 168, 226, 298 💬
68 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Carbamazepine 💬 Carbamazepine 3件:  6 , 13, 231 💬
69 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Cifenline 💬 Cibenzoline 1件: 58 💬
70 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Eleclazine 💬 Eleclazine 1件: 58 💬
71 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Flecainide 💬 Flecainide 1件:  6  💬
72 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lamotrigine 💬 Lamotrigine 5件: 13, 34, 38, 114, 144 💬
73 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Levobupivacaine 💬 Levobupivacaine 1件: 46 💬
74 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lidocaine 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
75 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine 13件:  6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬
76 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Mexiletine 💬 Mexiletine 5件:  1 ,  2 , 10, 113, 114 💬
77 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬
78 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Oxybuprocaine 💬 Oxybuprocaine 1件:  6  💬
79 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Phenytoin 💬 Phenytoin 1件: 13 💬
80 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Quinidine 💬 Quinidine 3件:  2 ,  8 , 13 💬
81 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Ropivacaine 💬 Ropivacaine 4件: 22, 36, 46, 70 💬
82 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Rufinamide 💬 Rufinamide 1件: 144 💬
83 Adrenergic signaling in cardiomyocytes 💬
 1件: SCN5A 💬 Zonisamide 💬 Zonisamide 1件:  6  💬