Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
CD3D 3件: CD3D, CD3E, CD3G 💬
|
Otelixizumab Otelixizumab 💬
| Otelixizumab | 046 1件: 46 💬
|
| 2 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
CD3D 3件: CD3D, CD3E, CD3G 💬
|
Visilizumab Visilizumab 💬
| Visilizumab | 096 2件: 96, 97 💬
|
| 3 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
CD3E 1件: CD3E 💬
|
Mosunetuzumab Mosunetuzumab 💬
| Mosunetuzumab | 049 1件: 49 💬
|
| 4 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
CD4 1件: CD4 💬
|
Zanolimumab Zanolimumab 💬
| Zanolimumab | 046 1件: 46 💬
|
| 5 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IFNG 1件: IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 3件: 49, 65, 107 💬
|
| 6 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IFNG 1件: IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 1件: 46 💬
|
| 7 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬
|
| 8 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL17A 1件: IL17A 💬
|
Ixekizumab Ixekizumab 💬
| Ixekizumab | 036 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬
|
| 9 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
| 10 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL17A 1件: IL17A 💬
|
Tibulizumab Tibulizumab 💬
| Tibulizumab | 053 1件: 53 💬
|
| 11 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL17A 2件: IL17A, IL17F 💬
|
Bimekizumab Bimekizumab 💬
| Bimekizumab | 046 3件: 46, 97, 271 💬
|
| 12 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
| 13 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 14 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 4件: 51, 106, 107, 266 💬
|
| 15 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1B 2件: IL1B, IL6 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 16 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL1R1 1件: IL1R1 💬
|
Anakinra Anakinra 💬
| Anakinra | 002 18件: 2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
|
| 17 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL22 1件: IL22 💬
|
Efmarodocokin alfa Efmarodocokin alfa 💬
| Efmarodocokin alfa | 096 2件: 96, 97 💬
|
| 18 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Brazikumab Brazikumab 💬
| Brazikumab | 096 2件: 96, 97 💬
|
| 19 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 5件: 37, 41, 51, 96, 97 💬
|
| 20 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Mirikizumab Mirikizumab 💬
| Mirikizumab | 037 3件: 37, 96, 97 💬
|
| 21 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Risankizumab Risankizumab 💬
| Risankizumab | 037 4件: 37, 96, 97, 271 💬
|
| 22 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Tildrakizumab Tildrakizumab 💬
| Tildrakizumab | 162 2件: 162, 271 💬
|
| 23 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL23A 1件: IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 16件: 37, 40, 41, 46, 49, 50, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 24 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL2RA 1件: IL2RA 💬
|
Basiliximab Basiliximab 💬
| Basiliximab | 002 6件: 2 , 50, 66, 97, 222, 228 💬
|
| 25 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL2RA 1件: IL2RA 💬
|
Daclizumab Daclizumab 💬
| Daclizumab | 013 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
|
| 26 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL2RA 3件: IL2RA, IL2RB, IL2RG 💬
|
Aldesleukin Aldesleukin 💬
| Aldesleukin | 002 6件: 2 , 35, 49, 65, 96, 97 💬
|
| 27 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL4 1件: IL4 💬
|
Binetrakin Binetrakin 💬
| Binetrakin | 046 1件: 46 💬
|
| 28 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL4R 1件: IL4R 💬
|
Dupilumab Dupilumab 💬
| Dupilumab | 051 5件: 51, 97, 98, 160, 162 💬
|
| 29 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6 1件: IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 2件: 46, 96 💬
|
| 30 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6 1件: IL6 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 5件: 28, 51, 85, 227, 331 💬
|
| 31 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6 1件: IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 2件: 28, 331 💬
|
| 32 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
| 33 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Sarilumab Sarilumab 💬
| Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬
|
| 34 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Satralizumab Satralizumab 💬
| Satralizumab | 011 3件: 11, 13, 86 💬
|
| 35 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬
|
Tocilizumab Tocilizumab 💬
| Tocilizumab | 002 21件: 2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬
|
| 36 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 1件: JAK1 💬
|
Abrocitinib Abrocitinib 💬
| Abrocitinib | 084 1件: 84 💬
|
| 37 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 1件: JAK1 💬
|
Filgotinib Filgotinib 💬
| Filgotinib | 046 6件: 46, 53, 96, 97, 222, 271 💬
|
| 38 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 1件: JAK1 💬
|
Itacitinib Itacitinib 💬
| Itacitinib | 046 4件: 46, 51, 97, 228 💬
|
| 39 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 8件: 40, 41, 46, 49, 96, 97, 107, 271 💬
|
| 40 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 13件: 2 , 41, 46, 49, 50, 51, 53, 93, 107, 162, 265, 269, 325 💬
|
| 41 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Ruxolitinib Ruxolitinib 💬
| Ruxolitinib | 060 3件: 60, 65, 228 💬
|
| 42 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 1件: 46 💬
|
| 43 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 011 15件: 11, 40, 44, 46, 49, 50, 51, 53, 65, 84, 96, 97, 107, 271, 300 💬
|
| 44 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
LCK 1件: LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 45 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
LCK 1件: LCK 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
| 46 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 2件: 113, 222 💬
|
| 47 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MAPK11 4件: MAPK11, MAPK12, MAPK13, MAPK14 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 1件: 8 💬
|
| 48 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR 1件: MTOR 💬
|
Everolimus Everolimus 💬
| Everolimus | 034 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
|
| 49 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR 1件: MTOR 💬
|
Sirolimus Sirolimus 💬
| Sirolimus | 002 40件: 2 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 300, 331 💬
|
| 50 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
MTOR 1件: MTOR 💬
|
Temsirolimus Temsirolimus 💬
| Temsirolimus | 013 1件: 13 💬
|
| 51 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
NFKB1 1件: NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 5件: 46, 51, 53, 271, 300 💬
|
| 52 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Cyclosporine Cyclosporine 💬
| Cyclosporine | 011 44件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
|
| 53 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Pimecrolimus Pimecrolimus 💬
| Pimecrolimus | 160 1件: 160 💬
|
| 54 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 55 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Tacrolimus Tacrolimus 💬
| Tacrolimus | 002 34件: 2 , 6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
|
| 56 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬
|
Voclosporin Voclosporin 💬
| Voclosporin | 049 2件: 49, 222 💬
|
| 57 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
PRKCQ 1件: PRKCQ 💬
|
Sotrastaurin Sotrastaurin 💬
| Sotrastaurin | 097 1件: 97 💬
|
| 58 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 1件: RARA 💬
|
Fenretinide Fenretinide 💬
| Fenretinide | 299 1件: 299 💬
|
| 59 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 1件: RARA 💬
|
Isotretinoin Isotretinoin 💬
| Isotretinoin | 036 4件: 36, 39, 159, 160 💬
|
| 60 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 1件: RARA 💬
|
Tamibarotene Tamibarotene 💬
| Tamibarotene | 026 2件: 26, 96 💬
|
| 61 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 1件: RARA 💬
|
Tretinoin Tretinoin 💬
| Tretinoin | 002 6件: 2 , 62, 63, 75, 94, 231 💬
|
| 62 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 1件: RARA 💬
|
Vitamin A Vitamin A 💬
| Vitamin A | 013 3件: 13, 53, 90 💬
|
| 63 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 4件: RARA, RXRA, RXRB, RXRG 💬
|
Acitretin Acitretin 💬
| Acitretin | 037 1件: 37 💬
|
| 64 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RARA 4件: RARA, RXRA, RXRB, RXRG 💬
|
Alitretinoin Alitretinoin 💬
| Alitretinoin | 049 1件: 49 💬
|
| 65 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RELA 1件: RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 1件: 113 💬
|
| 66 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
RXRA 3件: RXRA, RXRB, RXRG 💬
|
Bexarotene Bexarotene 💬
| Bexarotene | 013 2件: 13, 75 💬
|
| 67 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
TGFB1 1件: TGFB1 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 3件: 51, 85, 222 💬
|
| 68 | Th17 cell differentiation 💬 43 genes, 66 drugs (DrugBank) and 97 diseases |
TYK2 1件: TYK2 💬
|
Deucravacitinib Deucravacitinib 💬
| Deucravacitinib | 049 3件: 49, 96, 97 💬
|