Drug Description in Trials / DrugBank / KEGG DRUG

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DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

[2] Albendazole; Eskazole

[1] Albendazole 💬

-

-

[12] 5, 6, 7, 13, 28, 51, 67, 86, 96, 97, 114, 127 💬

Disease ID	Name
5	Progressive supranuclear palsy
6	Parkinson disease
7	Corticobasal degeneration
13	Multiple sclerosis/Neuromyelitis optica
28	Systemic amyloidosis
51	Scleroderma
67	Polycystic kidney disease
86	Pulmonary arterial hypertension
96	Crohn disease
97	Ulcerative colitis
114	Non-dystrophic myotonia syndrome
127	Frontotemporal lobar degeneration

2

[4] APOKYN; Apomorfina; Apomorphine; Apomorphine Hydrocloride

[1] Apomorphine 💬

[2] DRD1,
DRD2 💬

[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic s ...

[3] 5, 6, 7 💬

3

Botulinum toxin type A

[8] BOTOX; Botulinum toxin A; BOTULINUM TOXIN TYPE A; BTX-A; Dysport; IncobotulinumtoxinA; Onabotuli ...

[1] Botulinum toxin type A 💬

[1] SNAP25 💬

[2] Insulin secretion, Synaptic vesicle cycle 💬

[14] 2, 5, 6, 7, 13, 15, 17, 36, 47, 51, 70, 113, 149, 226 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
5	Progressive supranuclear palsy
6	Parkinson disease
7	Corticobasal degeneration
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
17	Multiple system atrophy
36	Epidermolysis bullosa
47	Buerger disease
51	Scleroderma
70	Spinal stenosis
113	Muscular dystrophy
149	Hemiconvulsion hemiplegia epilepsy syndrome
226	Interstitial cystitis with Hunners ulcer

4

-

-

-

[11] 1, 2, 5, 6, 8, 46, 49, 50, 113, 156, 201 💬

Disease ID	Name
1	Spinal and bulbar muscular atrophy
2	Amyotrophic lateral sclerosis
5	Progressive supranuclear palsy
6	Parkinson disease
8	Huntington disease
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
113	Muscular dystrophy
156	Rett syndrome
201	Angelman syndrome

5

[1] Davunetide 💬

-

-

[3] 5, 7, 127 💬

6

[3] ARICEPT; DONEPEZIL; Donepezil Hydrochloride

[1] Donepezil 💬

[1] ACHE 💬

[2] Cholinergic synapse, Glycerophospholipid metabolism 💬

[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬

Disease ID	Name
5	Progressive supranuclear palsy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
78	Hypopituitarism
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
127	Frontotemporal lobar degeneration
156	Rett syndrome
206	Fragile X syndrome

7

[4] DOPS; Droxidopa; L-DOPS; Northera

[1] Droxidopa 💬

[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬

Name	Full Name
ADRA1A	adrenoceptor alpha 1A
ADRA1B	adrenoceptor alpha 1B
ADRA1D	adrenoceptor alpha 1D
ADRA2A	adrenoceptor alpha 2A
ADRA2B	adrenoceptor alpha 2B
ADRA2C	adrenoceptor alpha 2C
ADRB1	adrenoceptor beta 1
ADRB2	adrenoceptor beta 2
ADRB3	adrenoceptor beta 3

[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chem ...

[5] 5, 6, 17, 169, 170 💬

8

-

-

-

[2] 5, 17 💬

9

[1] Fasudil 💬

[2] ROCK1,
ROCK2 💬

[23] Axon guidance, Chemokine signaling pathway, Focal adhesion, Human cytomegalovirus infection, Le ...

[4] 2, 5, 7, 51 💬

10

[1] Flortaucipir

[1] Flortaucipir F 18 💬

[1] MAPT 💬

[4] Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - mu ...

[3] 5, 7, 127 💬

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