Drug Description in Trials / DrugBank / KEGG DRUG

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No.

DrugBank

Drug (Description in trials)

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

1

Estradiol
(Estradiol / Norethindrone Acetate)

[1] Estradiol 💬

Name	Other Names
Estradiol	Estradiol (JAN/USP/INN) Climara (TN) Divigel (TN) Estrace (TN) Estraderm (TN) Estrasorb (TN) Estring (TN) Estrogel (TN) Innofem (TN) Vagifem (TN) Vivelle (TN) IMVEXXY MENOSTAR MINIVELLE VIVELLE-DOT DOTTI ESTRADIOL TRANSDERMAL SYSTEM ESTRADIOL VAGINAL ESTRADIOL VAGINAL CREAM LYLLANA YUVAFEM

[2] ESR1,
ESR2 💬

[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬

[7] 13, 46, 49, 65, 76, 226, 299 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
65	Primary immunodeficiency
76	Pituitary gonadotropin secretion hyperthyroidism
226	Interstitial cystitis with Hunners ulcer
299	Cystic fibrosis

2

Ethinylestradiol
(Norethindrone and ethinyl estradiol)

[3] Ethinyl estradiol; ETHINYLESTRADIOL; Ortho-Novum 777

[1] Ethinyl estradiol 💬

[1] ESR1 💬

[9] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬

[4] 13, 46, 49, 299 💬

3

Norethisterone
(Norethindrone)

[3] Norethindrone; Ortho-novum; Ortho-Novum 777

[1] Norethindrone 💬

[1] PGR 💬

[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬

[4] 13, 46, 49, 299 💬