Target Gene/Pathway Pathway / Gene

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KEGG GENES

KEGG PATHWAY

KEGG DRUG

DrugBank

Disease ID

1

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Name	Other Names
Estradiol	Estradiol (JAN/USP/INN) Climara (TN) Divigel (TN) Estrace (TN) Estraderm (TN) Estrasorb (TN) Estring (TN) Estrogel (TN) Innofem (TN) Vagifem (TN) Vivelle (TN) IMVEXXY MENOSTAR MINIVELLE VIVELLE-DOT DOTTI ESTRADIOL TRANSDERMAL SYSTEM ESTRADIOL VAGINAL ESTRADIOL VAGINAL CREAM LYLLANA YUVAFEM

[7] 13, 46, 49, 65, 76, 226, 299 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
65	Primary immunodeficiency
76	Pituitary gonadotropin secretion hyperthyroidism
226	Interstitial cystitis with Hunners ulcer
299	Cystic fibrosis

2

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

[2] 13, 227 💬

3

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

[2] 46, 49 💬

4

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Fulvestrant 💬

[2] 49, 86 💬

5

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Estradiol valerate 💬

Estradiol valerate

[1] 65 💬

6

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Estriol tripropionate 💬

[2] 13, 227 💬

7

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

[1] 74 💬

8

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Prasterone 💬

[6] 49, 53, 83, 86, 96, 113 💬

9

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

Raloxifene 💬

[1] 46 💬

10

[7] Endocrine resistance, Estrogen signaling pathway, Prolactin signaling pathway, GnRH secretion, P ...

[3] 2, 113, 227 💬

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