Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Chlorpromazine 💬[1] Chlorpromazine[2] Chlorpromazine; Chlorpromazine Hydrochloride[13] ADRA2A,
ADRA2B,
ADRA2C,
CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
DRD2,
HRH1,
HTR2A,
HTR2B,
HTR2C 💬 		[22] Alcoholism, Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Cocaine addiction, Dopaminergic synapse, Gap junction, Gastric acid secretion, Inflammatory mediator regulation of TRP channels, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Rap1 signaling pathway, Regulation of actin cytoskeleton, Salivary secretion, Serotonergic synapse, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 254 💬
2 Cimetidine 💬[1] Cimetidine[1] Cimetidine[1] HRH2 💬 [3] Calcium signaling pathway, Gastric acid secretion, Neuroactive ligand-receptor interaction 💬[2] 2, 254 💬
3 Isoniazid 💬[1] Isoniazid[1] Isoniazid--[1] 254 💬
4 Deferasirox 💬[1] Deferasirox[2] Deferasirox; Exjade--[3] 254, 284, 286 💬
5 Stannsoporfin 💬[1] Stannsoporfin[1] Tin mesoporphyrin[2] HMOX1,
HMOX2 💬 		[10] Chemical carcinogenesis - reactive oxygen species, Ferroptosis, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatocellular carcinoma, Metabolic pathways, MicroRNAs in cancer, Mineral absorption, Pathways in cancer, Porphyrin metabolism 💬[1] 254 💬
6 Colestipol 💬[1] Colestipol[1] Colestipol--[1] 254 💬
7 Hydroxychloroquine 💬[1] Hydroxychloroquine[3] HYDROXYCHLOROQUINE; Hydroxychloroquine Sulfate; PLAQUENIL--[27] 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 89, 90, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
8 Hemin 💬[1] Hemin[2] Hemin; Panhematin[2] ALAS1,
ALAS2 💬 		[4] Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬[1] 254 💬
9 Afamelanotide 💬[1] Afamelanotide[2] Afamelanotide; SCENESSE[1] MC1R 💬 [2] Melanogenesis, Neuroactive ligand-receptor interaction 💬[3] 159, 161, 254 💬
10 Givosiran 💬[1] Givosiran[1] Givosiran[1] ALAS1 💬 [4] Biosynthesis of cofactors, Glycine, serine and threonine metabolism, Metabolic pathways, Porphyrin metabolism 💬[1] 254 💬