Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Dextran 1 💬 [1] Dextran[1] Dextran; --[4] 2, 62, 96, 97 💬
2 Diflunisal 💬 [1] Diflunisal[1] Diflunisal; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 28 💬
3 Danazol 💬 [1] Danazol[1] Danazol; [3] AR,
ESR1,
PGR 💬		[12] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[5] 60, 63, 64, 65, 285 💬
4 Desmopressin 💬 [1] Desmopressin[5] DDAVP; DESMOPRESSIN; Desmopressin Acetate; Desmopressine; Minirin; [2] AVPR2,
F8 💬		[4] Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬[6] 6, 64, 72, 75, 225, 288 💬
5 Dexamethasone 💬 [1] Dexamethasone[5] Decadron; Dexametasona; Dexamethasone; DEXAMETHASONE SODIUM PHOSPHATE; Maxidex; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
6 Diazepam 💬 [1] Diazepam[1] Diazepam; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[3] 46, 155, 298 💬
7 Diazoxide 💬 [1] Diazoxide[1] Diazoxide; [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[2] 13, 193 💬
8 Didanosine 💬 [1] Didanosine[1] Didanosine; --[2] 25, 265 💬
9 Digitoxin 💬 [1] Digitoxin[1] Digitoxin; [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 299 💬
10 Digoxin 💬 [1] Digoxin[1] Digoxin; [4] ATP1A1,
ATP1A2,
ATP1A3,
ATP1A4 💬		[18] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 8, 46, 210 💬
11 Dihydrotachysterol 💬 [1] Dihydrotachysterol[0] [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬-
12 Diphenhydramine 💬 [1] Diphenhydramine[2] Diphenhydramine; Diphenhydramine hydrochloride; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[8] 11, 13, 49, 51, 70, 86, 222, 256 💬
13 Dipyridamole 💬 [1] Dipyridamole[1] Dipyridamole; [2] PDE4A,
PDE5A 💬		[6] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 46, 49, 51, 66, 96, 224 💬
14 Dronabinol 💬 [1] Dronabinol[4] DELTA-9-TETRAHYDROCANNABINOL; DRONABINOL; Sativex; Tetrahydrocannabinol; [2] CNR1,
CNR2 💬		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[7] 2, 8, 13, 36, 46, 271, 298 💬
15 Doxycycline 💬 [1] Doxycycline[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets; --[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
16 Dexmedetomidine 💬 [1] Dexmedetomidine[4] Dexdor; DEXMEDETOMIDINA; Dexmedetomidine; DEXMEDETOMIDINE HYDROCHLORIDE; [3] ADRA2A,
ADRA2B,
ADRA2C 💬		[2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬[14] 2, 4, 6, 21, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬
17 Dichlorphenamide 💬 [1] Diclofenamide[1] Dichlorphenamide; [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 114 💬
18 Desflurane 💬 [1] Desflurane[1] Desflurane; --[2] 22, 296 💬
19 Dapsone 💬 [1] Dapsone[1] Dapsone; --[5] 35, 42, 60, 84, 162 💬
20 Dezocine 💬 [1] Dezocine[1] Dezocine; [2] OPRK1,
OPRM1 💬		[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬[1] 46 💬
21 Dimethyl sulfoxide 💬 [1] Dimethyl sulfoxide[2] Dimethyl sulfoxide; DMSO; --[1] 226 💬
22 Dydrogesterone 💬 [1] Dydrogesterone[1] DYDROGESTERONE; [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 13 💬
23 Droxidopa 💬 [1] Droxidopa[4] DOPS; Droxidopa; L-DOPS; Northera; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 5, 6, 17, 169, 170 💬
24 Domperidone 💬 [1] Domperidone[1] Domperidone; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
25 Dantrolene 💬 [1] Dantrolene[2] Dantrolene; Dantrolene sodium; --[2] 13, 233 💬
26 Dicloxacillin 💬 [1] Dicloxacillin[1] DICLOXACILLIN; --[1] 299 💬
27 Dipivefrin 💬 [1] Dipivefrin[2] Dipivefrin; Dipivefrine; [9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬		[14] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 6 💬
28 Desogestrel 💬 [1] Desogestrel[2] Desogestrel; Désogestrel; [2] ESR1,
PGR 💬		[11] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, Oocyte meiosis, Pathways in cancer, Progesterone-mediated oocyte maturation, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[1] 230 💬
29 Daclizumab 💬 [1] Daclizumab[3] Daclizumab; Zenapax; Zinbryta; [1] IL2RA 💬[11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
30 Darifenacin 💬 [1] Darifenacin[2] Darifenacin; Emselex; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13 💬
31 Darunavir 💬 [1] Darunavir[1] Darunavir; --[1] 2 💬
32 Dasatinib 💬 [1] Dasatinib[1] Dasatinib; [8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85 💬
33 Decitabine 💬 [1] Decitabine[1] Decitabine; [3] DNMT1,
DNMT3A,
DNMT3B 💬		[3] Cysteine and methionine metabolism, Metabolic pathways, MicroRNAs in cancer 💬[2] 60, 63 💬
34 Deferasirox 💬 [1] Deferasirox[2] DEFERASIROX; EXJADE; --[3] 254, 284, 286 💬
35 Deferoxamine 💬 [1] Deferoxamine[3] Deferoxamine; DESFERAL; Desferrioxamine; --[4] 51, 53, 284, 286 💬
36 Deflazacort 💬 [1] Deflazacort[1] DEFLAZACORT; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[2] 30, 113 💬
37 Denosumab 💬 [1] Denosumab[3] Denosumab; Prolia; XGEVA; [1] TNFSF11 💬[8] Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬[8] 46, 50, 70, 93, 95, 96, 274, 299 💬
38 Desloratadine 💬 [1] Desloratadine[1] Desloratadine; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[1] 13 💬
39 Dexrazoxane 💬 [1] Dexrazoxane[1] Dexrazoxane; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[1] 13 💬
40 Dextromethorphan 💬 [1] Dextromethorphan[4] Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; [6] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[11] 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156 💬
41 Dutasteride 💬 [1] Dutasteride[2] Dutasterida; Dutasteride; [2] SRD5A1,
SRD5A2 💬		[3] Metabolic pathways, Prostate cancer, Steroid hormone biosynthesis 💬[2] 1, 2 💬
42 Dimethyl fumarate 💬 [1] Dimethyl fumarate[3] Dimethyl fumarate; Dimethylfumarat; TECFIDERA; [1] KEAP1 💬[6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 49, 51, 86, 296 💬
43 Dobutamine 💬 [1] Dobutamine[2] Dobutamin; Dobutamine; [1] ADRB1 💬[11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 57, 58, 86, 215 💬
44 Doripenem 💬 [1] Doripenem[2] DORIBAX; Doripenem; --[1] 299 💬
45 Dornase alfa 💬 [1] Dornase alfa[3] Dornase alfa; Dornase alpha; Pulmozyme; --[2] 53, 299 💬
46 Doxorubicin 💬 [1] Doxorubicin[2] Doxorubicin; Doxorubicin Hydrochloride; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[5] 26, 28, 34, 65, 331 💬
47 Dalfampridine 💬 [1] Dalfampridine[7] 4-Aminopyridine; 4-AP; Ampyra; Dalfampridine; FAMPRIDINA; FAMPRIDINE; Fampyra; [4] KCNA4,
KCNC3,
KCND2,
KCND3 💬		[4] Cortisol synthesis and secretion, Cushing syndrome, Serotonergic synapse, Spinocerebellar ataxia 💬[5] 3, 4, 6, 13, 14 💬
48 Dasatinib 💬 [1] Dasatinib[1] Dasatinib; [8] ABL1,
EPHA2,
FYN,
KIT,
LCK,
PDGFRB,
SRC,
YES1 💬		[77] Acute myeloid leukemia, Adherens junction, Axon guidance, Bacterial invasion of epithelial cells, Bladder cancer, Breast cancer, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, GABAergic synapse, Gap junction, Glioma, GnRH signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Inflammatory mediator regulation of TRP channels, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Mitophagy - animal, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Primary immunodeficiency, Prion disease, Prolactin signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Sphingolipid signaling pathway, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Thyroid hormone signaling pathway, Tight junction, Tuberculosis, VEGF signaling pathway, Viral carcinogenesis, Viral myocarditis, Yersinia infection 💬[2] 51, 85 💬
49 Donkey glue 💬 [1] Gelatin[3] Gelatin; Gelatine; Sulfur Colloid; --[7] 19, 28, 62, 78, 97, 269, 299 💬
50 Dabigatran etexilate 💬 [1] Dabigatran etexilate[1] Dabigatran etexilate; [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[2] 51, 75 💬
51 Diacerein 💬 [1] Diacerein[1] Diacerein; --[3] 36, 46, 63 💬
52 Deferiprone 💬 [1] Deferiprone[2] Deferiprone; Ferriprox; --[6] 2, 6, 18, 120, 122, 233 💬
53 Daunorubicin 💬 [1] Daunorubicin[1] Daunorubicin; [2] TOP2A,
TOP2B 💬		[1] Platinum drug resistance 💬[1] 65 💬
54 Deanol 💬 [1] Deanol[1] Deanol; --[1] 6 💬
55 Delorazepam 💬 [1] Delorazepam[0] [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬-
56 Desipramine 💬 [1] Desipramine[1] Desipramine; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 120, 156 💬
57 Dexchlorpheniramine 💬 [1] Dexchlorpheniramine[1] Dexchlorpheniramine; [1] HRH1 💬[3] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction 💬[2] 13, 49 💬
58 Diclofenac 💬 [1] Diclofenac[3] Diclofenac; Diclofenac sodium; Diclofenac SR; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[5] 13, 34, 46, 78, 271 💬
59 Dihydrocodeine 💬 [1] Dihydrocodeine[0] [1] OPRM1 💬[3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬-
60 Dihydroergotoxine 💬 [1] Dihydroergotoxine[1] Dihydroergotoxine; --[1] 6 💬
61 Diltiazem 💬 [1] Diltiazem[2] Diltiazem; Diltiazem Hydrochloride; [4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[3] 51, 58, 86 💬
62 Diosmin 💬 [1] Diosmin[1] Diosmin; --[3] 46, 97, 265 💬
63 Dolasetron 💬 [1] Dolasetron[1] Dolasetron; [5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬		[2] Serotonergic synapse, Taste transduction 💬[1] 46 💬
64 Domperidone maleate 💬 [1] Domperidone[1] Domperidone; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[5] 6, 13, 17, 51, 230 💬
65 Donepezil 💬 [1] Donepezil[3] Aricept; Donepezil; Donepezil hydrochloride; [1] ACHE 💬[2] Cholinergic synapse, Glycerophospholipid metabolism 💬[9] 5, 6, 13, 46, 78, 124, 127, 156, 206 💬
66 Dopamine 💬 [1] Dopamine[2] Dopamina; Dopamine; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 6, 7, 74, 299 💬
67 Dorzolamide 💬 [1] Dorzolamide[1] Dorzolamide; [13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬		[7] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬[1] 90 💬
68 Doxazosin 💬 [1] Doxazosin[2] CARDURA; Doxazosin; [3] ADRA1A,
ADRA1B,
ADRA1D 💬		[7] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[2] 57, 67 💬
69 Doxepin 💬 [1] Doxepin[1] Doxepin; [3] HRH1,
SLC6A2,
SLC6A4 💬		[5] Calcium signaling pathway, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 6 💬
70 Doxycycline 💬 [1] Doxycycline[4] Doxycyclin; Doxycycline; DOXYCYCLINE HYCLATE; Doxycycline Tablets; --[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
71 Duloxetine 💬 [1] Duloxetine[3] Cymbalta; DULOXETINE; Duloxetine hydrochloride; [2] SLC6A2,
SLC6A4 💬		[2] Serotonergic synapse, Synaptic vesicle cycle 💬[2] 6, 13 💬
72 Dapagliflozin 💬 [1] Dapagliflozin[2] Dapagliflozin; Forxiga; [1] SLC5A2 💬[1] 💬[7] 19, 49, 66, 67, 86, 88, 222 💬
73 Dexlansoprazole 💬 [1] Dexlansoprazole[1] Dexlansoprazole; [2] ATP4A,
ATP4B 💬		[4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation 💬[1] 98 💬
74 Dirucotide 💬 [1] Dirucotide[1] Dirucotide; --[1] 13 💬
75 Davunetide 💬 [1] Davunetide[1] Davunetide; --[3] 5, 7, 127 💬
76 Duvoglustat 💬 [1] Duvoglustat[3] 1-deoxynojirimycin; Deoxynojirimycin; Duvoglustat; [1] GAA 💬[4] Galactose metabolism, Lysosome, Metabolic pathways, Starch and sucrose metabolism 💬[1] 256 💬
77 Dabigatran 💬 [1] Dabigatran[1] Dabigatran; [1] F2 💬[8] Complement and coagulation cascades, Coronavirus disease - COVID-19, Neuroactive ligand-receptor interaction, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Platelet activation, Regulation of actin cytoskeleton 💬[5] 51, 75, 85, 91, 124 💬
78 Dexpramipexole 💬 [1] Dexpramipexole[1] Dexpramipexole; [5] DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		[11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[1] 2 💬
79 Dulaglutide 💬 [1] Dulaglutide[2] Dulaglutide; Trulicity; [1] GLP1R 💬[3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬[2] 13, 299 💬
80 Dabrafenib 💬 [1] Dabrafenib[1] Dabrafenib; [1] BRAF 💬[44] Acute myeloid leukemia, Alcoholism, Alzheimer disease, Bladder cancer, Breast cancer, Chemical carcinogenesis - reactive oxygen species, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endometrial cancer, ErbB signaling pathway, Focal adhesion, FoxO signaling pathway, Gastric cancer, Glioma, Hepatitis B, Hepatitis C, Hepatocellular carcinoma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Regulation of actin cytoskeleton, Renal cell carcinoma, Serotonergic synapse, Thyroid cancer, Vascular smooth muscle contraction, cAMP signaling pathway, mTOR signaling pathway 💬[1] 34 💬
81 Dolutegravir 💬 [1] Dolutegravir[2] Dolutegravir; Triumeq; --[2] 2, 265 💬
82 Drisapersen 💬 [1] Drisapersen[1] Drisapersen; [1] DMD 💬[4] Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Viral myocarditis 💬[1] 113 💬
83 Dupilumab 💬 [1] Dupilumab[2] Dupilumab; Dupixent; [1] IL4R 💬[8] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Inflammatory bowel disease, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬[5] 51, 97, 98, 160, 162 💬
84 Deferitazole 💬 [1] Deferitazole[1] Deferitazole; --[1] 284 💬
85 Doravirine 💬 [1] Doravirine[1] Doravirine; --[1] 265 💬
86 Deutetrabenazine 💬 [1] Deutetrabenazine[1] Deutetrabenazine; [1] SLC18A2 💬[7] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Parkinson disease, Serotonergic synapse, Synaptic vesicle cycle 💬[1] 8 💬
87 Daratumumab 💬 [1] Daratumumab[2] Daratumumab; Darzalex; [1] CD38 💬[7] Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬[5] 13, 28, 48, 49, 63 💬
88 Durvalumab 💬 [1] Durvalumab[1] Durvalumab; [1] CD274 💬[2] Cell adhesion molecules, PD-L1 expression and PD-1 checkpoint pathway in cancer 💬[1] 85 💬
89 Domagrozumab 💬 [1] Domagrozumab[1] PF-06252616; [1] MSTN 💬[1] Cytokine-cytokine receptor interaction 💬[1] 113 💬
90 Diroximel fumarate 💬 [1] Diroximel fumarate[1] Diroximel Fumarate; --[1] 13 💬
91 Darvadstrocel 💬 [1] Darvadstrocel[2] Alofisel; DARVADSTROCEL; --[1] 96 💬
92 Deutivacaftor 💬 [1] Deutivacaftor[1] DEUTIVACAFTOR; [1] CFTR 💬[8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬[1] 299 💬
93 Dezamizumab 💬 [1] Dezamizumab[1] Dezamizumab; [1] APCS 💬[1] 💬[1] 28 💬
94 Danicopan 💬 [1] Danicopan[1] DANICOPAN; [1] CFD 💬[3] Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬[1] 62 💬
95 Daxdilimab 💬 [1] Daxdilimab[1] Daxdilimab; [1] LILRA4 💬[2] B cell receptor signaling pathway, Osteoclast differentiation 💬[2] 49, 50 💬
96 Deucravacitinib 💬 [1] Deucravacitinib[1] Deucravacitinib; [1] TYK2 💬[16] Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis 💬[3] 49, 96, 97 💬