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KEGG DRUG
DrugBank
Drug (Description in trials)
KEGG GENES
KEGG PATHWAY
Disease ID
1
Metformin
1.
Metformin
×
Name
Other Names
Metformin
Metformin (USAN/INN)
💬
[1]
Metformin
Metformin
[5]
Metformin
Metformin
;
Metformin HCl
;
Metformin hydrochloride
;
METFORMINA
;
Metformine
[2]
PRKAA1
PRKAA1
,
PRKAA2
💬
1.
Metformin
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
[20]
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
[20]
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
[25]
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113
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127
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158
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206
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218
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225
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233
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265
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285
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299
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301
💬
[25]
2
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6
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8
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13
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46
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49
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60
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65
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67
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75
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77
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81
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86
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97
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113
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127
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158
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206
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218
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225
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233
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265
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28
...
1.
Metformin
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
6
Parkinson disease
8
Huntington disease
13
Multiple sclerosis/Neuromyelitis optica
46
Malignant rheumatoid arthritis
49
Systemic lupus erythematosus
60
Aplastic anemia
65
Primary immunodeficiency
67
Polycystic kidney disease
75
Cushing disease
77
Growth hormone secreting pituitary adenoma
81
Congenital adrenal hyperplasia
86
Pulmonary arterial hypertension
97
Ulcerative colitis
113
Muscular dystrophy
127
Frontotemporal lobar degeneration
158
Tuberous sclerosis
206
Fragile X syndrome
218
Alport syndrome
225
Congenital nephrogenic diabetes insipidus
233
Wolfram syndrome
265
Lipodystrophy
285
Fanconi anemia
299
Cystic fibrosis
301
Macular dystrophy