Target Gene/Pathway Pathway / Gene
Search results
No. | KEGG PATHWAY | KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
---|---|---|---|---|---|
1 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF [1] BRAF 💬 |
Dabrafenib Dabrafenib 💬 |
Dabrafenib | 034 [1] 34 💬 💬 |
2 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
BRAF [3] BRAF, PDGFRB, RAF1 💬 |
Sorafenib Sorafenib 💬 |
Sorafenib | 034 [2] 34, 86 💬 💬 |
3 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
CDK4 [2] CDK4, CDK6 💬 |
Abemaciclib Abemaciclib 💬 |
Abemaciclib | 034 [1] 34 💬 💬 |
4 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Cetuximab Cetuximab 💬 |
Cetuximab | 051 [2] 51, 86 💬 💬 |
5 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Erlotinib Erlotinib 💬 |
Erlotinib | 094 [1] 94 💬 💬 |
6 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Gefitinib Gefitinib 💬 |
Gefitinib | 075 [1] 75 💬 💬 |
7 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Icotinib Icotinib 💬 |
Icotinib | 034 [1] 34 💬 💬 |
8 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Lapatinib Lapatinib 💬 |
Lapatinib | 034 [3] 34, 74, 75 💬 💬 |
9 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Neratinib Neratinib 💬 |
Neratinib | 034 [1] 34 💬 💬 |
10 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
EGFR [1] EGFR 💬 |
Tesevatinib Tesevatinib 💬 |
Tesevatinib | 067 [1] 67 💬 💬 |
11 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGF23 [1] FGF23 💬 |
Burosumab Burosumab 💬 |
Burosumab | 238 [1] 238 💬 💬 |
12 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGFR1 [1] FGFR1 💬 |
Infigratinib Infigratinib 💬 |
Infigratinib | 276 [1] 276 💬 💬 |
13 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
FGFR1 [3] FGFR1, PDGFRA, PDGFRB 💬 |
Nintedanib Nintedanib 💬 |
Nintedanib | 051 [5] 51, 85, 89, 227, 228 💬 💬 |
14 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬 |
Linsitinib Linsitinib 💬 |
Linsitinib | 232 [1] 232 💬 💬 |
15 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬 |
Mecasermin Mecasermin 💬 |
Mecasermin | 065 [6] 65, 78, 96, 168, 265, 299 💬 💬 |
16 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
IGF1R [1] IGF1R 💬 |
Teprotumumab Teprotumumab 💬 |
Teprotumumab | 051 [1] 51 💬 💬 |
17 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Binimetinib Binimetinib 💬 |
Binimetinib | 034 [1] 34 💬 💬 |
18 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Cobimetinib Cobimetinib 💬 |
Cobimetinib | 280 [1] 280 💬 💬 |
19 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Mirdametinib Mirdametinib 💬 |
Mirdametinib | 034 [1] 34 💬 💬 |
20 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Selumetinib Selumetinib 💬 |
Selumetinib | 034 [1] 34 💬 💬 |
21 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MAP2K1 [2] MAP2K1, MAP2K2 💬 |
Trametinib Trametinib 💬 |
Trametinib | 002 [4] 2 , 34, 279, 280 💬 💬 |
22 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
MET [1] MET 💬 |
Cabozantinib Cabozantinib 💬 |
Cabozantinib | 034 [1] 34 💬 💬 |
23 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [1] PDGFRA 💬 |
Imatinib Imatinib 💬 |
Imatinib | 013 [12] 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 💬 |
24 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Nilotinib Nilotinib 💬 |
Nilotinib | 006 [5] 6 , 8 , 34, 51, 86 💬 💬 |
25 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRA [2] PDGFRA, PDGFRB 💬 |
Sunitinib Sunitinib 💬 |
Sunitinib | 028 [2] 28, 34 💬 💬 |
26 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
27 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PDGFRB [1] PDGFRB 💬 |
Dasatinib Dasatinib 💬 |
Dasatinib | 051 [2] 51, 85 💬 💬 |
28 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PIK3CA [1] PIK3CA 💬 |
Alpelisib Alpelisib 💬 |
Alpelisib | 138 [1] 138 💬 💬 |
29 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PIK3CA [3] PIK3CA, PIK3CB, PIK3CD 💬 |
Leniolisib Leniolisib 💬 |
Leniolisib | 053 [2] 53, 65 💬 💬 |
30 | Melanoma 💬 16 genes, 29 drugs (DrugBank) and 35 diseases |
PIK3CD [1] PIK3CD 💬 |
Parsaclisib Parsaclisib 💬 |
Parsaclisib | 035 [3] 35, 53, 61 💬 💬 |