15. 封入体筋炎 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 42 / 薬物数 : 33 - (DrugBank : 11) / 標的遺伝子数 : 12 - 標的パスウェイ数 : 123
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
ABC008
Abcuro, Inc.
2021 Phase 1 NCT04659031 Australia;
ADSVF
Assistance Publique - Hôpitaux de Paris
2021 Phase 1 NCT05032131 -
Alemtuzumab (Campath)
National Institute of Neurological Disorders and Stroke (NINDS)
2004 Phase 2 NCT00079768 United States;
Anakinra
Karolinska Institutet
2003 Phase 2/Phase 3 NCT01165008 Sweden;
Arimoclomol
Orphazyme
2019 Phase 3 NCT04049097 United Kingdom;United States;
2017 Phase 2 NCT02753530 United Kingdom;United States;
Richard Barohn, MD
2008 Phase 2/Phase 3 NCT00769860 United Kingdom;United States;
UCL - The Joint UCLH/UCL Comprehensive Biomedical Research Unit
2009 Phase 2 EUCTR2008-008208-42-GB United Kingdom;
Arimoclomol citrate
Orphazyme A/S
2019 Phase 3 EUCTR2019-000749-11-GB United Kingdom;United States;
2018 Phase 2;Phase 3 EUCTR2017-004903-33-GB United Kingdom;United States;
BRX-345
Orphazyme A/S
2019 Phase 3 EUCTR2019-000749-11-GB United Kingdom;United States;
2018 Phase 2;Phase 3 EUCTR2017-004903-33-GB United Kingdom;United States;
UCL - The Joint UCLH/UCL Comprehensive Biomedical Research Unit
2009 Phase 2 EUCTR2008-008208-42-GB United Kingdom;
BYM338
NOVARTIS FARMA S.P.A.
2015 Phase 3 EUCTR2015-001411-12-IT Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Novartis Farma SpA
2014 Phase 3 EUCTR2013-000705-23-IT Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Novartis Pharma K.K.
2015 Phase 2-3 JPRN-JapicCTI-153078 -
2013 Phase 2-3 JPRN-JapicCTI-132365 -
Novartis Pharma Services AG
2015 Phase 3 EUCTR2015-001411-12-NL Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-GB Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-FR Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-DK Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-BE Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2014 Phase 3 EUCTR2013-000705-23-GB Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 Phase 3 EUCTR2013-000705-23-DK Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 Phase 3 EUCTR2013-000705-23-DE Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 - EUCTR2013-000705-23-NL Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 - EUCTR2013-000705-23-BE Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Novartis Pharmaceuticals
2011 Phase 2 NCT01423110 United States;
BYM338 (Bimagrumab)
Novartis Pharmaceuticals
2014 Phase 2/Phase 3 NCT02250443 United States;
BYM338/bimagrumab
Novartis Pharmaceuticals
2013 Phase 2/Phase 3 NCT01925209 Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Bimagrumab
NOVARTIS FARMA S.P.A.
2015 Phase 3 EUCTR2015-001411-12-IT Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Novartis Farma SpA
2014 Phase 3 EUCTR2013-000705-23-IT Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Novartis Pharma K.K.
2015 Phase 2-3 JPRN-JapicCTI-153078 -
2013 Phase 2-3 JPRN-JapicCTI-132365 -
Novartis Pharma Services AG
2015 Phase 3 EUCTR2015-001411-12-NL Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-GB Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-FR Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-DK Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-BE Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Novartis Pharmaceuticals
2015 Phase 3 NCT02573467 Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Blood draw for optional genetic exome sequencing
LMU Klinikum
2022 - NCT05272969 Germany;
Calcium
LMU Klinikum
2022 - NCT05272969 Germany;
Care as usual
University of Southern Denmark
2015 - NCT02317094 Denmark;
Creatine
LMU Klinikum
2022 - NCT05272969 Germany;
Etanercept
Washington University School of Medicine
2005 Phase 0 NCT00802815 United States;
FLEBOGAMMA
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
2007 - EUCTR2006-005942-35-IT Italy;
Gamma Globulin
National Institute of Neurological Disorders and Stroke (NINDS)
1990 Phase 2 NCT00001261 United States;
Genetic test: ACE polymorphism
LMU Klinikum
2022 - NCT05272969 Germany;
Genetic test: ACTN3 polymorphism
LMU Klinikum
2022 - NCT05272969 Germany;
Immunoglobulins, normal human, for intravascular adm.
ISTITUTO NEUROLOGICO CARLO BESTA
2007 - EUCTR2007-004359-12-IT Italy;
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
2007 - EUCTR2006-005942-35-IT Italy;
Magnesium
LMU Klinikum
2022 - NCT05272969 Germany;
Natalizumab
Phoenix Neurological Associates, LTD
2013 Phase 1 NCT02483845 United States;
Phenylbutyrate Oral Tablet
University of Kansas Medical Center
2020 Phase 1 NCT04421677 United States;
Phosphate
LMU Klinikum
2022 - NCT05272969 Germany;
Pioglitazone
Johns Hopkins University
2018 Phase 1 NCT03440034 United States;
RAAV1.CMV.huFollistatin344
Nationwide Children's Hospital
2012 Phase 1 NCT01519349 United States;
REGN2477+REGN1033
Regeneron Pharmaceuticals
2019 Phase 2 NCT03710941 -
Rapamycin
Institut National de la Santé Et de la Recherche Médicale, France
2015 Phase 2/Phase 3 NCT02481453 France;
Simvastatin
ISTITUTO NEUROLOGICO CARLO BESTA
2007 - EUCTR2007-004359-12-IT Italy;
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
2007 - EUCTR2006-005942-35-IT Italy;
Sirolimus
University of Kansas Medical Center
2022 Phase 3 NCT04789070 United States;
Vitamin D
LMU Klinikum
2022 - NCT05272969 Germany;
Xeomin
Rigshospitalet
2014 Phase 2 EUCTR2014-002210-23-DK Denmark;
Abcuro, Inc.
2021 Phase 1 NCT04659031 Australia;
ADSVF
Assistance Publique - Hôpitaux de Paris
2021 Phase 1 NCT05032131 -
Alemtuzumab (Campath)
National Institute of Neurological Disorders and Stroke (NINDS)
2004 Phase 2 NCT00079768 United States;
Anakinra
Karolinska Institutet
2003 Phase 2/Phase 3 NCT01165008 Sweden;
Arimoclomol
Orphazyme
2019 Phase 3 NCT04049097 United Kingdom;United States;
2017 Phase 2 NCT02753530 United Kingdom;United States;
Richard Barohn, MD
2008 Phase 2/Phase 3 NCT00769860 United Kingdom;United States;
UCL - The Joint UCLH/UCL Comprehensive Biomedical Research Unit
2009 Phase 2 EUCTR2008-008208-42-GB United Kingdom;
Arimoclomol citrate
Orphazyme A/S
2019 Phase 3 EUCTR2019-000749-11-GB United Kingdom;United States;
2018 Phase 2;Phase 3 EUCTR2017-004903-33-GB United Kingdom;United States;
BRX-345
Orphazyme A/S
2019 Phase 3 EUCTR2019-000749-11-GB United Kingdom;United States;
2018 Phase 2;Phase 3 EUCTR2017-004903-33-GB United Kingdom;United States;
UCL - The Joint UCLH/UCL Comprehensive Biomedical Research Unit
2009 Phase 2 EUCTR2008-008208-42-GB United Kingdom;
BYM338
NOVARTIS FARMA S.P.A.
2015 Phase 3 EUCTR2015-001411-12-IT Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Novartis Farma SpA
2014 Phase 3 EUCTR2013-000705-23-IT Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Novartis Pharma K.K.
2015 Phase 2-3 JPRN-JapicCTI-153078 -
2013 Phase 2-3 JPRN-JapicCTI-132365 -
Novartis Pharma Services AG
2015 Phase 3 EUCTR2015-001411-12-NL Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-GB Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-FR Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-DK Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-BE Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2014 Phase 3 EUCTR2013-000705-23-GB Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 Phase 3 EUCTR2013-000705-23-DK Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 Phase 3 EUCTR2013-000705-23-DE Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 - EUCTR2013-000705-23-NL Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
2014 - EUCTR2013-000705-23-BE Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Novartis Pharmaceuticals
2011 Phase 2 NCT01423110 United States;
BYM338 (Bimagrumab)
Novartis Pharmaceuticals
2014 Phase 2/Phase 3 NCT02250443 United States;
BYM338/bimagrumab
Novartis Pharmaceuticals
2013 Phase 2/Phase 3 NCT01925209 Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Bimagrumab
NOVARTIS FARMA S.P.A.
2015 Phase 3 EUCTR2015-001411-12-IT Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Novartis Farma SpA
2014 Phase 3 EUCTR2013-000705-23-IT Australia;Belgium;Denmark;France;Germany;Italy;Japan;Netherlands;Poland;Switzerland;United Kingdom;United States;
Novartis Pharma K.K.
2015 Phase 2-3 JPRN-JapicCTI-153078 -
2013 Phase 2-3 JPRN-JapicCTI-132365 -
Novartis Pharma Services AG
2015 Phase 3 EUCTR2015-001411-12-NL Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-GB Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-FR Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-DK Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
2015 Phase 3 EUCTR2015-001411-12-BE Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Novartis Pharmaceuticals
2015 Phase 3 NCT02573467 Australia;Belgium;Denmark;France;Italy;Japan;Netherlands;Switzerland;United Kingdom;United States;
Blood draw for optional genetic exome sequencing
LMU Klinikum
2022 - NCT05272969 Germany;
Calcium
LMU Klinikum
2022 - NCT05272969 Germany;
Care as usual
University of Southern Denmark
2015 - NCT02317094 Denmark;
Creatine
LMU Klinikum
2022 - NCT05272969 Germany;
Etanercept
Washington University School of Medicine
2005 Phase 0 NCT00802815 United States;
FLEBOGAMMA
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
2007 - EUCTR2006-005942-35-IT Italy;
Gamma Globulin
National Institute of Neurological Disorders and Stroke (NINDS)
1990 Phase 2 NCT00001261 United States;
Genetic test: ACE polymorphism
LMU Klinikum
2022 - NCT05272969 Germany;
Genetic test: ACTN3 polymorphism
LMU Klinikum
2022 - NCT05272969 Germany;
Immunoglobulins, normal human, for intravascular adm.
ISTITUTO NEUROLOGICO CARLO BESTA
2007 - EUCTR2007-004359-12-IT Italy;
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
2007 - EUCTR2006-005942-35-IT Italy;
Magnesium
LMU Klinikum
2022 - NCT05272969 Germany;
Natalizumab
Phoenix Neurological Associates, LTD
2013 Phase 1 NCT02483845 United States;
Phenylbutyrate Oral Tablet
University of Kansas Medical Center
2020 Phase 1 NCT04421677 United States;
Phosphate
LMU Klinikum
2022 - NCT05272969 Germany;
Pioglitazone
Johns Hopkins University
2018 Phase 1 NCT03440034 United States;
RAAV1.CMV.huFollistatin344
Nationwide Children's Hospital
2012 Phase 1 NCT01519349 United States;
REGN2477+REGN1033
Regeneron Pharmaceuticals
2019 Phase 2 NCT03710941 -
Rapamycin
Institut National de la Santé Et de la Recherche Médicale, France
2015 Phase 2/Phase 3 NCT02481453 France;
Simvastatin
ISTITUTO NEUROLOGICO CARLO BESTA
2007 - EUCTR2007-004359-12-IT Italy;
POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
2007 - EUCTR2006-005942-35-IT Italy;
Sirolimus
University of Kansas Medical Center
2022 Phase 3 NCT04789070 United States;
Vitamin D
LMU Klinikum
2022 - NCT05272969 Germany;
Xeomin
Rigshospitalet
2014 Phase 2 EUCTR2014-002210-23-DK Denmark;