25. 進行性多巣性白質脳症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 26 / 薬物数 : 35 - (DrugBank : 22) / 標的遺伝子数 : 8 - 標的パスウェイ数 : 37
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
111JC101
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom;
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom;
2008 - EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom;
CYT107
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States;
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States;
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States;
Cidofovir
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States;
Collection of blood and urine
University Hospital, Toulouse
2021 - NCT04453917 France;
Cytarabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Didanosine
Bristol-Myers Squibb
1997 - NCT00002274 United States;
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Enfuvirtide
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France;
Filgrastim
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Interferon alfa-2b
University of Miami
1997 - NCT00002270 United States;
Lariam
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom;
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom;
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom;
2008 - EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom;
Mefloquine
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom;
Biogen
2009 Phase 1/Phase 2 NCT00746941 Australia;Brazil;France;Germany;Italy;Puerto Rico;Spain;United Kingdom;United States;
Department of Neurology, Shimane University Hospital
2016 - JPRN-UMIN000022151 Japan;
Nagoya City University
2016 - JPRN-UMIN000023752 Japan;
Methylprednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States;
NT-I7
National Institute of Neurological Disorders and Stroke (NINDS)
2021 Early Phase 1 NCT04781309 United States;
Natalizumab
Biogen
2019 - NCT05236777 Czechia;
Neurological evaluation
University Hospital, Toulouse
2021 - NCT04453917 France;
Pembrolizumab
First Affiliated Hospital of Zhejiang University
2019 Phase 2 NCT04091932 China;
Prednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States;
Probenecid
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States;
PyVST
National Institute of Neurological Disorders and Stroke (NINDS)
2016 Early Phase 1 NCT02694783 United States;
Recombinant human interleukin-7
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States;
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States;
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States;
Spinal tap
University Hospital, Toulouse
2021 - NCT04453917 France;
Tenofovir-Emtricitabine
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France;
Teriflunomide
Providence Health & Services
2013 Phase 4 NCT01970410 United States;
Topotecan
SmithKline Beecham
1996 Phase 2 NCT00002395 United States;
Tysabri
Biogen
2018 - NCT03399981 United States;
Zalcitabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Zidovudine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
University of Miami
1997 - NCT00002270 United States;
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom;
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom;
2008 - EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom;
CYT107
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States;
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States;
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States;
Cidofovir
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States;
Collection of blood and urine
University Hospital, Toulouse
2021 - NCT04453917 France;
Cytarabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Didanosine
Bristol-Myers Squibb
1997 - NCT00002274 United States;
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Enfuvirtide
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France;
Filgrastim
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Interferon alfa-2b
University of Miami
1997 - NCT00002270 United States;
Lariam
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom;
Biogen Idec Ltd
2009 - EUCTR2008-001314-24-GB France;Italy;Spain;United Kingdom;
2008 Phase 2 EUCTR2008-001314-24-FR France;Italy;Spain;United Kingdom;
2008 - EUCTR2008-001314-24-ES France;Italy;Spain;United Kingdom;
Mefloquine
BIOGEN IDEC LTD
2009 - EUCTR2008-001314-24-IT France;Italy;Spain;United Kingdom;
Biogen
2009 Phase 1/Phase 2 NCT00746941 Australia;Brazil;France;Germany;Italy;Puerto Rico;Spain;United Kingdom;United States;
Department of Neurology, Shimane University Hospital
2016 - JPRN-UMIN000022151 Japan;
Nagoya City University
2016 - JPRN-UMIN000023752 Japan;
Methylprednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States;
NT-I7
National Institute of Neurological Disorders and Stroke (NINDS)
2021 Early Phase 1 NCT04781309 United States;
Natalizumab
Biogen
2019 - NCT05236777 Czechia;
Neurological evaluation
University Hospital, Toulouse
2021 - NCT04453917 France;
Pembrolizumab
First Affiliated Hospital of Zhejiang University
2019 Phase 2 NCT04091932 China;
Prednisolone
Biogen
2010 Phase 4 NCT01211665 Germany;United States;
Probenecid
National Institute of Allergy and Infectious Diseases (NIAID)
1999 - NCT00000945 United States;
PyVST
National Institute of Neurological Disorders and Stroke (NINDS)
2016 Early Phase 1 NCT02694783 United States;
Recombinant human interleukin-7
CYTHERIS
2012 - EUCTR2012-000725-41-IT Italy;Spain;Switzerland;United Kingdom;United States;
Cytheris S.A.
2013 - EUCTR2012-000725-41-GB European Union;Italy;Spain;Switzerland;United Kingdom;United States;
2012 - EUCTR2012-000725-41-ES European Union;Spain;Switzerland;United Kingdom;United States;
Spinal tap
University Hospital, Toulouse
2021 - NCT04453917 France;
Tenofovir-Emtricitabine
French National Agency for Research on AIDS and Viral Hepatitis
2005 Phase 2 NCT00120367 France;
Teriflunomide
Providence Health & Services
2013 Phase 4 NCT01970410 United States;
Topotecan
SmithKline Beecham
1996 Phase 2 NCT00002395 United States;
Tysabri
Biogen
2018 - NCT03399981 United States;
Zalcitabine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
Zidovudine
National Institute of Allergy and Infectious Diseases (NIAID)
1998 Phase 2 NCT00001048 United States;
University of Miami
1997 - NCT00002270 United States;