34. 神経線維腫症 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 133 / 薬物数 : 186 - (DrugBank : 67) / 標的遺伝子数 : 79 - 標的パスウェイ数 : 190
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
11C]-methionine
Guys' and St. Thomas' NHS Foundation Trust
2011 - EUCTR2010-019759-23-GB United Kingdom;
2-amino-4-(methyl[11C]sulfanyl)butanoic acid
Guys' and St. Thomas' NHS Foundation Trust
2011 - EUCTR2010-019759-23-GB United Kingdom;
755nm Alexandrite Laser
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
980nm laser
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
AL2846 capsules
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021 Phase 1/Phase 2 NCT05011019 China;
AMN107
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
AR-42
Massachusetts Eye and Ear Infirmary
2015 Early Phase 1 NCT02282917 United States;
AZD2014
Massachusetts General Hospital
2016 Phase 2 NCT02831257 United States;
AZD6244
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
National Cancer Institute (NCI)
2011 Phase 1/Phase 2 NCT01362803 United States;
Abemaciclib
National Cancer Institute (NCI)
2021 Phase 1/Phase 2 NCT04750928 United States;
Acetaminophen
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Afinitor
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2011-002228-42-FR France;
Aminolevulinic acid
Harry T Whelan, MD
2016 Phase 2 NCT02728388 United States;
Antigen-specific T cells CART/CTL and DCvac
Shenzhen Geno-Immune Medical Institute
2019 Phase 1/Phase 2 NCT04085159 China;
Aspirin
Massachusetts Eye and Ear Infirmary
2018 Phase 2 NCT03079999 United States;
Axitinib
NYU Langone Health
2014 Phase 2 NCT02129647 United States;
Bevacizumab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
National Cancer Institute (NCI)
2010 Phase 2 NCT01207687 United States;
Northwestern University
2010 Phase 2 NCT01125046 United States;
Sarcoma Alliance for Research through Collaboration
2012 Phase 2 NCT01661283 United States;
Shanghai Ninth People's Hospital affiliated to Shanghai JiaoTong University, School of Medicine
2018 - ChiCTR1800016040 China;
University of Alabama at Birmingham
2013 Phase 2 NCT01767792 United States;
Bevacizumab (Genitical Recombination)
Kiyoshi Saito
2019 Phase 2 JPRN-JapicCTI-194999 Japan;
Binimetinib
University of Alabama at Birmingham
2017 Phase 2 NCT03231306 United States;
Bony Toxicity
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Brigatinib
Scott R. Plotkin, MD, PhD
2020 Phase 2 NCT04374305 United States;
Cabozantinib
University of Alabama at Birmingham
2014 Phase 2 NCT02101736 United States;
Carboplatin
Children's Oncology Group
2006 Phase 1 NCT00352495 Canada;United States;
National Cancer Institute (NCI)
2020 Phase 3 NCT04166409 Canada;Puerto Rico;United States;
2019 Phase 3 NCT03871257 Canada;Puerto Rico;United States;
Cediranib Maleate
National Cancer Institute (NCI)
2006 Phase 2 NCT00326872 United States;
Celecoxib (Celebrex)
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Cetuximab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Cholecalciferol
University of Utah
2017 Phase 2 NCT01968590 Canada;Germany;United States;
Control Group
University of Alabama at Birmingham
2016 - NCT02718131 Australia;United States;
Conventional surgery
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Crizotinib
University of Alabama at Birmingham
2020 Phase 2 NCT04283669 United States;
Dabrafenib
Novartis Pharmaceuticals
2019 Phase 4 NCT03975829 Canada;France;Spain;United Kingdom;United States;
Pediatric Brain Tumor Consortium
2019 Phase 1/Phase 2 NCT04201457 United States;
Dexmedetomidine
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Diclofenac Sodium
Fundação Educacional Serra dos Órgãos
2017 Phase 2 NCT03090971 Brazil;
Doxorubicin hydrochloride
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Endostatin
Beijing Tiantan Hospital
2014 Phase 2 NCT02104323 China;
Etoposide
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Everolimus
Novartis Pharmaceuticals
- Phase 4 EUCTR2016-001563-36-Outside-EU/EEA Israel;
Sarcoma Alliance for Research through Collaboration
2012 Phase 2 NCT01661283 United States;
The University of Texas Health Science Center, Houston
2015 Phase 2 NCT02332902 United States;
Everolimus (RAD001)
Novartis Pharmaceuticals
2012 Phase 2 NCT01365468 Israel;
Everolimus (RAD001) , Afinitor®
New York University School of Medicine
2011 Phase 2 NCT01419639 United States;
Evérolimus
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2011-002228-42-FR France;
FCN-159
Shanghai Fosun Pharmaceutical Development Co, Ltd.
2021 Phase 1/Phase 2 NCT04954001 -
Filgrastim
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Fludeoxyglucose F 18
Children's Hospital of Philadelphia
2002 - NCT00060008 United States;
GLIVEC 100 mg comprimidos recubiertos con película
HOSPITAL SANT JOAN DE DÉU
2010 - EUCTR2009-016922-15-ES Spain;
GLIVEC 400 mg comprimidos recubiertos con película
HOSPITAL SANT JOAN DE DÉU
2010 - EUCTR2009-016922-15-ES Spain;
Gadolinium contrast
Washington University School of Medicine
2013 - NCT02584413 United States;
Gadopentetate
Children's Hospital of Philadelphia
2002 - NCT00060008 United States;
Gleevec
Indiana University
2006 Phase 2 NCT01673009 United States;
Kent Robertson
2012 Phase 1/Phase 2 NCT01140360 United States;
Glycopyrrolate
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Gold
Shanghai 9th People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine
2016 - ChiCTR-DDD-16009551 China;
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
2020 Phase 0 ChiCTR2000036770 China;
Hydroxychloroquine
Pediatric Brain Tumor Consortium
2019 Phase 1/Phase 2 NCT04201457 United States;
INFUSE Bone Graft (BMP-2)
University of Alabama at Birmingham
2016 - NCT02718131 Australia;United States;
Icotinib
Li Peng
2016 Phase 2 NCT02934256 China;
Ifosfamide
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Imatinib Mesylate
Indiana University
2018 Phase 2 NCT03688568 United States;
St. Justine's Hospital
2014 Phase 2 NCT02177825 Canada;
Imiquimod Cream
Massachusetts General Hospital
2009 Phase 1 NCT00865644 United States;
Isotonic sodium chloride solution
Kiyoshi Saito
2019 Phase 2 JPRN-JapicCTI-194999 Japan;
Koselugo
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Kybella
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
Lamotrigin beta
Technische Universität München, Fakultät für Medizin
2018 Phase 2 EUCTR2016-005022-10-DE Germany;
Lamotrigine
Erasmus Medical Center
2014 Phase 2/Phase 3 NCT02256124 Belgium;Netherlands;Spain;
Lamotrigine dispers
Erasmus MC
2018 Phase 2 EUCTR2013-003405-26-DK Belgium;Denmark;Netherlands;Spain;
2017 Phase 2 EUCTR2013-003405-26-ES Belgium;Netherlands;Spain;
2015 - EUCTR2013-003405-26-BE Belgium;Netherlands;
2014 - EUCTR2013-003405-26-NL Netherlands;
Lapatinib
New York University School of Medicine
2009 Phase 2 NCT00973739 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2009 Early Phase 1 NCT00863122 United States;
Lenalidomide
National Cancer Institute (NCI)
2012 Phase 2 NCT01553149 Australia;Canada;New Zealand;United States;
Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 1
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 2
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 3
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Lidocaine Injectable Solution
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Lovastatin
University of California, Los Angeles
2009 Phase 1 NCT00352599 United States;
University of Coimbra
2019 - NCT03826940 Portugal;
Vanderbilt University
2016 Phase 2 NCT02964884 United States;
Lovastatin ™
University of Alabama at Birmingham
2009 Phase 2 NCT00853580 Australia;United States;
MRI, FDG-PET/CT scans
National Cancer Institute (NCI)
2014 Phase 1 NCT02211768 United States;
Magnetic resonance imaging
Washington University School of Medicine
2013 - NCT02584413 United States;
Mekinist
ErasmusMC
2019 Phase 2 EUCTR2019-001317-16-NL Netherlands;
VO Barnmedicin, Skånes University Hospital
2018 Phase 2 EUCTR2018-001846-32-SE Sweden;
Methotrexate
Children's Hospital of Philadelphia
2001 Phase 2 NCT00030264 United States;
Methylphenidate
Hospices Civils de Lyon
2004 Phase 4 NCT00169611 France;
Mirdametinib (MEK Inhibitor)
SpringWorks Therapeutics, Inc.
2021 - NCT05028166 -
Mirdametinib (PD-0325901) oral capsule or dispersible tablet
SpringWorks Therapeutics, Inc.
2019 Phase 2 NCT03962543 United States;
N-Acetyl cysteine
Children's Hospital Medical Center, Cincinnati
2020 Phase 2 NCT04481048 United States;
N-acetylcysteine (NAC)
Children's Hospital Medical Center, Cincinnati
2019 Phase 2 NCT04481035 United States;
NFX-179 Gel
NFlection Therapeutics, Inc.
2020 Phase 2 NCT04435665 United States;
NFX-179 gel
NFlection Therapeutics, Inc.
2021 Phase 2 NCT05005845 United States;
NILOTINIB HYDROCHLORIDE MONOHYDRATE
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
NPC-12G gel
Nobelpharma
2020 Phase 3 NCT04461886 Japan;
Nexavar
Plymouth Hospital NHS Trust
2011 Phase 4 EUCTR2011-001789-16-GB United Kingdom;
Nexavar (BAY 43-9006) (Sorafenib)
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter
Mayo Clinic
2017 Phase 1 NCT02700230 United States;
PD-0325901
University of Alabama at Birmingham
2014 Phase 2 NCT02096471 United States;
PTC299
PTC Therapeutics
2009 Phase 2 NCT00911248 United States;
Part 1 Levulan injection
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Part 1 Levulan surface application twice with microneedling
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Peg-Interferon alpha-2b
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Pharmacodynamics
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Pirfenidone
Mayo Clinic
2000 Phase 2 NCT00754780 -
National Cancer Institute (NCI)
2004 Phase 2 NCT00076102 United States;
2002 Phase 1 NCT00053937 United States;
Poly ICLC
University of Alabama at Birmingham
2021 Phase 2 NCT04544007 United States;
Pomalidomide
National Cancer Institute (NCI)
2015 Phase 1 NCT02415153 United States;
Propofol
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
QOL assessment, Neuropsychological
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Quality-of-life assessment
National Cancer Institute (NCI)
2010 Phase 2 NCT01207687 United States;
RAD001
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2011-002228-42-FR France;
Assistance Publique - Hôpitaux de Paris
2012 Phase 2 NCT01490476 France;
NYU Langone Health
2013 Early Phase 1 NCT01880749 United States;
Novartis Pharmaceuticals
- Phase 4 EUCTR2016-001563-36-Outside-EU/EEA Israel;
RAD001, everolimus
Jonsson Comprehensive Cancer Center
2015 Phase 2 NCT01345136 United States;
RAD001: Everolimus
Assistance Publique - Hôpitaux de Paris
2011 Phase 2 NCT01412892 France;
REC-2282
Recursion Pharmaceuticals Inc.
2021 Phase 2/Phase 3 NCT05130866 -
Radiofrequency
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
Radiographic Evaluation
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Ranibizumab
Massachusetts General Hospital
2008 Phase 0 NCT00657202 United States;
Rapamycin
Department of Dermatology Graduate School of Medicine, Osaka University
2014 Phase 2,3 JPRN-UMIN000015081 Japan;
Saline Solution
Fundação Educacional Serra dos Órgãos
2017 Phase 2 NCT03090971 Brazil;
Selumetinib
AstraZeneca
2021 Phase 3 NCT04924608 Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
2021 Phase 1 NCT05101148 Poland;Russian Federation;Spain;United States;
2020 Phase 1 NCT04590235 China;
2020 Phase 1 NCT04495127 Japan;
2017 - NCT03259633 United States;
AstraZeneca KK
2020 Phase 1 JPRN-JapicCTI-205422 Japan, North America;
Children's Hospital Medical Center, Cincinnati
2017 Phase 2 NCT03095248 United States;
Great Ormond Street Hospital for Children NHS Foundation Trust
2019 Phase 1/Phase 2 NCT03326388 United Kingdom;
National Cancer Institute (NCI)
2016 Phase 2 NCT02407405 United States;
2015 Phase 2 NCT02644512 United States;
2010 Phase 1/Phase 2 NCT01089101 United States;
Sarcoma Alliance for Research through Collaboration
2019 Phase 2 NCT03433183 United States;
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
2020 Phase 0 ChiCTR2000036770 China;
University of Alabama at Birmingham
2017 Phase 2 NCT03105258 United States;
Yamaji Shigeyuki
2021 Phase 3 JPRN-jRCT2041210036 Australia;Brasil;Canada;China;France;Germany;Italy;Japan;Netherland;Poland;Russia;Spain;UK;USA;
Selumetinib (AZD6244 hyd sulfate) 25mg/m2
National Cancer Institute (NCI)
2017 Phase 2 NCT03109301 United States;
Selumetinib (AZD6244 hyd sulfate) 50mg/dose
National Cancer Institute (NCI)
2017 Phase 2 NCT03109301 United States;
Selumetinib 10mg capsule
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Selumetinib 25mg capsule
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Selumetinib Hyd-sulphate
Great Ormond Street Hospital
2018 Phase 1;Phase 2 EUCTR2017-002635-41-GB United Kingdom;
Selumetinib Sulfate
National Cancer Institute (NCI)
2020 Phase 3 NCT04166409 Canada;Puerto Rico;United States;
2019 Phase 3 NCT03871257 Canada;Puerto Rico;United States;
2017 Phase 2 NCT02839720 United States;
Selumetinib capsules
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
Selumetinib granules in sprinkle capsules for opening
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
Selumetinib hyd-sulfate
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Selumetinib sulfate
Great Ormond Street Hospital
2018 Phase 1;Phase 2 EUCTR2017-002635-41-GB United Kingdom;
Sevoflurane
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Simvastatin 20mg/5ml Oral Suspension
Central Manchester University Hospitals NHS Foundation Trust
2013 Phase 2 EUCTR2012-005742-38-GB United Kingdom;
Single Photon Emission Computed Tomography
Mayo Clinic
2017 Phase 1 NCT02700230 United States;
Sirolimus
Osaka University Hospital
2016 Phase 2 JPRN-UMIN000021030 Japan;
Sarcoma Alliance for Research through Collaboration
2019 Phase 2 NCT03433183 United States;
University of Alabama at Birmingham
2008 Phase 2 NCT00652990 United States;
2008 Phase 2 NCT00634270 United States;
Skincerity plus sirolimus/rapamycin
The University of Texas Health Science Center, Houston
2009 Phase 1 NCT01031901 United States;
Skinercity plus sirolimus/rapamycin
The University of Texas Health Science Center, Houston
2009 Phase 1 NCT01031901 United States;
Sorafenib (as tosylate)
Plymouth Hospital NHS Trust
2011 Phase 4 EUCTR2011-001789-16-GB United Kingdom;
Sunitinib
Memorial Sloan Kettering Cancer Center
2007 Phase 2 NCT00589784 United States;
Sutent®/Sunitinib
Indiana University
2012 Phase 2 NCT01402817 United States;
Tarceva and Rapamycin
Roger Packer
2007 Phase 1 NCT00901849 United States;
Tasigna
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
Indiana University
2011 Early Phase 1 NCT01275586 United States;
Plymouth Hospital NHS Trust
2011 Phase 4 EUCTR2010-023508-28-GB United Kingdom;
Temozolomide (temodar)
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Temsirolimus
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Tipifarnib
National Cancer Institute (NCI)
2001 Phase 2 NCT00021541 Germany;United States;
Toxicity, Pharmacokinetics
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Trametinib
National Cancer Institute (NCI)
2017 Phase 2 NCT03190915 United States;
Novartis Pharmaceuticals
2019 Phase 4 NCT03975829 Canada;France;Spain;United Kingdom;United States;
Pediatric Brain Tumor Consortium
2019 Phase 1/Phase 2 NCT04201457 United States;
Region Skane
2019 Phase 2 NCT03741101 Sweden;
University of California, San Francisco
2018 Phase 2 NCT03232892 United States;
Treatment A
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Treatment B
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Treatment C
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Treatment D
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Turalio
National Cancer Institute (NCI)
2015 Phase 1/Phase 2 NCT02390752 United States;
Unknown
Leiden University Medical Center
2021 Phase 2 EUCTR2020-000156-35-NL Netherlands;
VINBLASTINE SULPHATE
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
Vehicle Gel
NFlection Therapeutics, Inc.
2020 Phase 2 NCT04435665 United States;
Vehicle gel
NFlection Therapeutics, Inc.
2021 Phase 2 NCT05005845 United States;
Vinblastine
Children's Hospital of Philadelphia
2001 Phase 2 NCT00030264 United States;
Vinblastine sulfate
Children's Oncology Group
2006 Phase 1 NCT00352495 Canada;United States;
Vincristine Sulfate
National Cancer Institute (NCI)
2020 Phase 3 NCT04166409 Canada;Puerto Rico;United States;
2019 Phase 3 NCT03871257 Canada;Puerto Rico;United States;
Vincristine Sulfate (Oncovin)
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Votubia
Novartis Pharmaceuticals
- Phase 4 EUCTR2016-001563-36-Outside-EU/EEA Israel;
[18F]-FLT-PET/CT scans
National Cancer Institute (NCI)
2014 Phase 1 NCT02211768 United States;
Guys' and St. Thomas' NHS Foundation Trust
2011 - EUCTR2010-019759-23-GB United Kingdom;
2-amino-4-(methyl[11C]sulfanyl)butanoic acid
Guys' and St. Thomas' NHS Foundation Trust
2011 - EUCTR2010-019759-23-GB United Kingdom;
755nm Alexandrite Laser
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
980nm laser
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
AL2846 capsules
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
2021 Phase 1/Phase 2 NCT05011019 China;
AMN107
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
AR-42
Massachusetts Eye and Ear Infirmary
2015 Early Phase 1 NCT02282917 United States;
AZD2014
Massachusetts General Hospital
2016 Phase 2 NCT02831257 United States;
AZD6244
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
National Cancer Institute (NCI)
2011 Phase 1/Phase 2 NCT01362803 United States;
Abemaciclib
National Cancer Institute (NCI)
2021 Phase 1/Phase 2 NCT04750928 United States;
Acetaminophen
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Afinitor
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2011-002228-42-FR France;
Aminolevulinic acid
Harry T Whelan, MD
2016 Phase 2 NCT02728388 United States;
Antigen-specific T cells CART/CTL and DCvac
Shenzhen Geno-Immune Medical Institute
2019 Phase 1/Phase 2 NCT04085159 China;
Aspirin
Massachusetts Eye and Ear Infirmary
2018 Phase 2 NCT03079999 United States;
Axitinib
NYU Langone Health
2014 Phase 2 NCT02129647 United States;
Bevacizumab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
National Cancer Institute (NCI)
2010 Phase 2 NCT01207687 United States;
Northwestern University
2010 Phase 2 NCT01125046 United States;
Sarcoma Alliance for Research through Collaboration
2012 Phase 2 NCT01661283 United States;
Shanghai Ninth People's Hospital affiliated to Shanghai JiaoTong University, School of Medicine
2018 - ChiCTR1800016040 China;
University of Alabama at Birmingham
2013 Phase 2 NCT01767792 United States;
Bevacizumab (Genitical Recombination)
Kiyoshi Saito
2019 Phase 2 JPRN-JapicCTI-194999 Japan;
Binimetinib
University of Alabama at Birmingham
2017 Phase 2 NCT03231306 United States;
Bony Toxicity
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Brigatinib
Scott R. Plotkin, MD, PhD
2020 Phase 2 NCT04374305 United States;
Cabozantinib
University of Alabama at Birmingham
2014 Phase 2 NCT02101736 United States;
Carboplatin
Children's Oncology Group
2006 Phase 1 NCT00352495 Canada;United States;
National Cancer Institute (NCI)
2020 Phase 3 NCT04166409 Canada;Puerto Rico;United States;
2019 Phase 3 NCT03871257 Canada;Puerto Rico;United States;
Cediranib Maleate
National Cancer Institute (NCI)
2006 Phase 2 NCT00326872 United States;
Celecoxib (Celebrex)
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Cetuximab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Cholecalciferol
University of Utah
2017 Phase 2 NCT01968590 Canada;Germany;United States;
Control Group
University of Alabama at Birmingham
2016 - NCT02718131 Australia;United States;
Conventional surgery
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Crizotinib
University of Alabama at Birmingham
2020 Phase 2 NCT04283669 United States;
Dabrafenib
Novartis Pharmaceuticals
2019 Phase 4 NCT03975829 Canada;France;Spain;United Kingdom;United States;
Pediatric Brain Tumor Consortium
2019 Phase 1/Phase 2 NCT04201457 United States;
Dexmedetomidine
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Diclofenac Sodium
Fundação Educacional Serra dos Órgãos
2017 Phase 2 NCT03090971 Brazil;
Doxorubicin hydrochloride
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Endostatin
Beijing Tiantan Hospital
2014 Phase 2 NCT02104323 China;
Etoposide
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Everolimus
Novartis Pharmaceuticals
- Phase 4 EUCTR2016-001563-36-Outside-EU/EEA Israel;
Sarcoma Alliance for Research through Collaboration
2012 Phase 2 NCT01661283 United States;
The University of Texas Health Science Center, Houston
2015 Phase 2 NCT02332902 United States;
Everolimus (RAD001)
Novartis Pharmaceuticals
2012 Phase 2 NCT01365468 Israel;
Everolimus (RAD001) , Afinitor®
New York University School of Medicine
2011 Phase 2 NCT01419639 United States;
Evérolimus
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2011-002228-42-FR France;
FCN-159
Shanghai Fosun Pharmaceutical Development Co, Ltd.
2021 Phase 1/Phase 2 NCT04954001 -
Filgrastim
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Fludeoxyglucose F 18
Children's Hospital of Philadelphia
2002 - NCT00060008 United States;
GLIVEC 100 mg comprimidos recubiertos con película
HOSPITAL SANT JOAN DE DÉU
2010 - EUCTR2009-016922-15-ES Spain;
GLIVEC 400 mg comprimidos recubiertos con película
HOSPITAL SANT JOAN DE DÉU
2010 - EUCTR2009-016922-15-ES Spain;
Gadolinium contrast
Washington University School of Medicine
2013 - NCT02584413 United States;
Gadopentetate
Children's Hospital of Philadelphia
2002 - NCT00060008 United States;
Gleevec
Indiana University
2006 Phase 2 NCT01673009 United States;
Kent Robertson
2012 Phase 1/Phase 2 NCT01140360 United States;
Glycopyrrolate
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Gold
Shanghai 9th People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine
2016 - ChiCTR-DDD-16009551 China;
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
2020 Phase 0 ChiCTR2000036770 China;
Hydroxychloroquine
Pediatric Brain Tumor Consortium
2019 Phase 1/Phase 2 NCT04201457 United States;
INFUSE Bone Graft (BMP-2)
University of Alabama at Birmingham
2016 - NCT02718131 Australia;United States;
Icotinib
Li Peng
2016 Phase 2 NCT02934256 China;
Ifosfamide
Sarcoma Alliance for Research through Collaboration
2005 Phase 2 NCT00304083 Canada;United States;
Imatinib Mesylate
Indiana University
2018 Phase 2 NCT03688568 United States;
St. Justine's Hospital
2014 Phase 2 NCT02177825 Canada;
Imiquimod Cream
Massachusetts General Hospital
2009 Phase 1 NCT00865644 United States;
Isotonic sodium chloride solution
Kiyoshi Saito
2019 Phase 2 JPRN-JapicCTI-194999 Japan;
Koselugo
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Kybella
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
Lamotrigin beta
Technische Universität München, Fakultät für Medizin
2018 Phase 2 EUCTR2016-005022-10-DE Germany;
Lamotrigine
Erasmus Medical Center
2014 Phase 2/Phase 3 NCT02256124 Belgium;Netherlands;Spain;
Lamotrigine dispers
Erasmus MC
2018 Phase 2 EUCTR2013-003405-26-DK Belgium;Denmark;Netherlands;Spain;
2017 Phase 2 EUCTR2013-003405-26-ES Belgium;Netherlands;Spain;
2015 - EUCTR2013-003405-26-BE Belgium;Netherlands;
2014 - EUCTR2013-003405-26-NL Netherlands;
Lapatinib
New York University School of Medicine
2009 Phase 2 NCT00973739 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2009 Early Phase 1 NCT00863122 United States;
Lenalidomide
National Cancer Institute (NCI)
2012 Phase 2 NCT01553149 Australia;Canada;New Zealand;United States;
Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 1
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 2
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Levulan (5-aminolevulinic acid) photodynamic therapy - Dose level 3
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Lidocaine Injectable Solution
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Lovastatin
University of California, Los Angeles
2009 Phase 1 NCT00352599 United States;
University of Coimbra
2019 - NCT03826940 Portugal;
Vanderbilt University
2016 Phase 2 NCT02964884 United States;
Lovastatin ™
University of Alabama at Birmingham
2009 Phase 2 NCT00853580 Australia;United States;
MRI, FDG-PET/CT scans
National Cancer Institute (NCI)
2014 Phase 1 NCT02211768 United States;
Magnetic resonance imaging
Washington University School of Medicine
2013 - NCT02584413 United States;
Mekinist
ErasmusMC
2019 Phase 2 EUCTR2019-001317-16-NL Netherlands;
VO Barnmedicin, Skånes University Hospital
2018 Phase 2 EUCTR2018-001846-32-SE Sweden;
Methotrexate
Children's Hospital of Philadelphia
2001 Phase 2 NCT00030264 United States;
Methylphenidate
Hospices Civils de Lyon
2004 Phase 4 NCT00169611 France;
Mirdametinib (MEK Inhibitor)
SpringWorks Therapeutics, Inc.
2021 - NCT05028166 -
Mirdametinib (PD-0325901) oral capsule or dispersible tablet
SpringWorks Therapeutics, Inc.
2019 Phase 2 NCT03962543 United States;
N-Acetyl cysteine
Children's Hospital Medical Center, Cincinnati
2020 Phase 2 NCT04481048 United States;
N-acetylcysteine (NAC)
Children's Hospital Medical Center, Cincinnati
2019 Phase 2 NCT04481035 United States;
NFX-179 Gel
NFlection Therapeutics, Inc.
2020 Phase 2 NCT04435665 United States;
NFX-179 gel
NFlection Therapeutics, Inc.
2021 Phase 2 NCT05005845 United States;
NILOTINIB HYDROCHLORIDE MONOHYDRATE
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
NPC-12G gel
Nobelpharma
2020 Phase 3 NCT04461886 Japan;
Nexavar
Plymouth Hospital NHS Trust
2011 Phase 4 EUCTR2011-001789-16-GB United Kingdom;
Nexavar (BAY 43-9006) (Sorafenib)
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Oncolytic Measles Virus Encoding Thyroidal Sodium Iodide Symporter
Mayo Clinic
2017 Phase 1 NCT02700230 United States;
PD-0325901
University of Alabama at Birmingham
2014 Phase 2 NCT02096471 United States;
PTC299
PTC Therapeutics
2009 Phase 2 NCT00911248 United States;
Part 1 Levulan injection
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Part 1 Levulan surface application twice with microneedling
Harry T Whelan, MD
2012 Phase 1 NCT01682811 United States;
Peg-Interferon alpha-2b
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Pharmacodynamics
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Pirfenidone
Mayo Clinic
2000 Phase 2 NCT00754780 -
National Cancer Institute (NCI)
2004 Phase 2 NCT00076102 United States;
2002 Phase 1 NCT00053937 United States;
Poly ICLC
University of Alabama at Birmingham
2021 Phase 2 NCT04544007 United States;
Pomalidomide
National Cancer Institute (NCI)
2015 Phase 1 NCT02415153 United States;
Propofol
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
QOL assessment, Neuropsychological
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Quality-of-life assessment
National Cancer Institute (NCI)
2010 Phase 2 NCT01207687 United States;
RAD001
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
- Phase 2 EUCTR2011-002228-42-FR France;
Assistance Publique - Hôpitaux de Paris
2012 Phase 2 NCT01490476 France;
NYU Langone Health
2013 Early Phase 1 NCT01880749 United States;
Novartis Pharmaceuticals
- Phase 4 EUCTR2016-001563-36-Outside-EU/EEA Israel;
RAD001, everolimus
Jonsson Comprehensive Cancer Center
2015 Phase 2 NCT01345136 United States;
RAD001: Everolimus
Assistance Publique - Hôpitaux de Paris
2011 Phase 2 NCT01412892 France;
REC-2282
Recursion Pharmaceuticals Inc.
2021 Phase 2/Phase 3 NCT05130866 -
Radiofrequency
Massachusetts General Hospital
2021 Phase 1 NCT04730583 -
Radiographic Evaluation
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Ranibizumab
Massachusetts General Hospital
2008 Phase 0 NCT00657202 United States;
Rapamycin
Department of Dermatology Graduate School of Medicine, Osaka University
2014 Phase 2,3 JPRN-UMIN000015081 Japan;
Saline Solution
Fundação Educacional Serra dos Órgãos
2017 Phase 2 NCT03090971 Brazil;
Selumetinib
AstraZeneca
2021 Phase 3 NCT04924608 Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
2021 Phase 1 NCT05101148 Poland;Russian Federation;Spain;United States;
2020 Phase 1 NCT04590235 China;
2020 Phase 1 NCT04495127 Japan;
2017 - NCT03259633 United States;
AstraZeneca KK
2020 Phase 1 JPRN-JapicCTI-205422 Japan, North America;
Children's Hospital Medical Center, Cincinnati
2017 Phase 2 NCT03095248 United States;
Great Ormond Street Hospital for Children NHS Foundation Trust
2019 Phase 1/Phase 2 NCT03326388 United Kingdom;
National Cancer Institute (NCI)
2016 Phase 2 NCT02407405 United States;
2015 Phase 2 NCT02644512 United States;
2010 Phase 1/Phase 2 NCT01089101 United States;
Sarcoma Alliance for Research through Collaboration
2019 Phase 2 NCT03433183 United States;
Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
2020 Phase 0 ChiCTR2000036770 China;
University of Alabama at Birmingham
2017 Phase 2 NCT03105258 United States;
Yamaji Shigeyuki
2021 Phase 3 JPRN-jRCT2041210036 Australia;Brasil;Canada;China;France;Germany;Italy;Japan;Netherland;Poland;Russia;Spain;UK;USA;
Selumetinib (AZD6244 hyd sulfate) 25mg/m2
National Cancer Institute (NCI)
2017 Phase 2 NCT03109301 United States;
Selumetinib (AZD6244 hyd sulfate) 50mg/dose
National Cancer Institute (NCI)
2017 Phase 2 NCT03109301 United States;
Selumetinib 10mg capsule
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Selumetinib 25mg capsule
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Selumetinib Hyd-sulphate
Great Ormond Street Hospital
2018 Phase 1;Phase 2 EUCTR2017-002635-41-GB United Kingdom;
Selumetinib Sulfate
National Cancer Institute (NCI)
2020 Phase 3 NCT04166409 Canada;Puerto Rico;United States;
2019 Phase 3 NCT03871257 Canada;Puerto Rico;United States;
2017 Phase 2 NCT02839720 United States;
Selumetinib capsules
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
Selumetinib granules in sprinkle capsules for opening
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
Selumetinib hyd-sulfate
ASTRAZENECA AB
2021 Phase 3 EUCTR2020-005607-39-IT Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
AstraZeneca AB
2022 Phase 1;Phase 2 EUCTR2020-005608-20-NL Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2022 Phase 1;Phase 2 EUCTR2020-005608-20-ES Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 3 EUCTR2020-005607-39-ES Australia;Brazil;Canada;China;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United States;
2021 Phase 1;Phase 2 EUCTR2020-005608-20-DE Germany;Italy;Netherlands;Russian Federation;Spain;United States;
2021 Phase 1 EUCTR2020-005648-52-PL Poland;Russian Federation;Spain;United States;
Selumetinib sulfate
Great Ormond Street Hospital
2018 Phase 1;Phase 2 EUCTR2017-002635-41-GB United Kingdom;
Sevoflurane
Medical College of Wisconsin
2018 Phase 4 NCT03513757 United States;
Simvastatin 20mg/5ml Oral Suspension
Central Manchester University Hospitals NHS Foundation Trust
2013 Phase 2 EUCTR2012-005742-38-GB United Kingdom;
Single Photon Emission Computed Tomography
Mayo Clinic
2017 Phase 1 NCT02700230 United States;
Sirolimus
Osaka University Hospital
2016 Phase 2 JPRN-UMIN000021030 Japan;
Sarcoma Alliance for Research through Collaboration
2019 Phase 2 NCT03433183 United States;
University of Alabama at Birmingham
2008 Phase 2 NCT00652990 United States;
2008 Phase 2 NCT00634270 United States;
Skincerity plus sirolimus/rapamycin
The University of Texas Health Science Center, Houston
2009 Phase 1 NCT01031901 United States;
Skinercity plus sirolimus/rapamycin
The University of Texas Health Science Center, Houston
2009 Phase 1 NCT01031901 United States;
Sorafenib (as tosylate)
Plymouth Hospital NHS Trust
2011 Phase 4 EUCTR2011-001789-16-GB United Kingdom;
Sunitinib
Memorial Sloan Kettering Cancer Center
2007 Phase 2 NCT00589784 United States;
Sutent®/Sunitinib
Indiana University
2012 Phase 2 NCT01402817 United States;
Tarceva and Rapamycin
Roger Packer
2007 Phase 1 NCT00901849 United States;
Tasigna
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
Indiana University
2011 Early Phase 1 NCT01275586 United States;
Plymouth Hospital NHS Trust
2011 Phase 4 EUCTR2010-023508-28-GB United Kingdom;
Temozolomide (temodar)
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Temsirolimus
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Tipifarnib
National Cancer Institute (NCI)
2001 Phase 2 NCT00021541 Germany;United States;
Toxicity, Pharmacokinetics
National Cancer Institute (NCI)
2008 Phase 1 NCT00727233 United States;
Trametinib
National Cancer Institute (NCI)
2017 Phase 2 NCT03190915 United States;
Novartis Pharmaceuticals
2019 Phase 4 NCT03975829 Canada;France;Spain;United Kingdom;United States;
Pediatric Brain Tumor Consortium
2019 Phase 1/Phase 2 NCT04201457 United States;
Region Skane
2019 Phase 2 NCT03741101 Sweden;
University of California, San Francisco
2018 Phase 2 NCT03232892 United States;
Treatment A
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Treatment B
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Treatment C
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Treatment D
AstraZeneca
2018 Phase 1 NCT03649165 United States;
Turalio
National Cancer Institute (NCI)
2015 Phase 1/Phase 2 NCT02390752 United States;
Unknown
Leiden University Medical Center
2021 Phase 2 EUCTR2020-000156-35-NL Netherlands;
VINBLASTINE SULPHATE
Gustave Roussy
2013 Phase 2 EUCTR2012-003005-10-DK Denmark;France;Netherlands;Spain;Switzerland;
Vehicle Gel
NFlection Therapeutics, Inc.
2020 Phase 2 NCT04435665 United States;
Vehicle gel
NFlection Therapeutics, Inc.
2021 Phase 2 NCT05005845 United States;
Vinblastine
Children's Hospital of Philadelphia
2001 Phase 2 NCT00030264 United States;
Vinblastine sulfate
Children's Oncology Group
2006 Phase 1 NCT00352495 Canada;United States;
Vincristine Sulfate
National Cancer Institute (NCI)
2020 Phase 3 NCT04166409 Canada;Puerto Rico;United States;
2019 Phase 3 NCT03871257 Canada;Puerto Rico;United States;
Vincristine Sulfate (Oncovin)
Spectrum Health Hospitals
2008 Phase 2 NCT00846430 United States;
Votubia
Novartis Pharmaceuticals
- Phase 4 EUCTR2016-001563-36-Outside-EU/EEA Israel;
[18F]-FLT-PET/CT scans
National Cancer Institute (NCI)
2014 Phase 1 NCT02211768 United States;