60. 再生不良性貧血 Disease details / Clinical trials / Drug dev / DR info
臨床試験数 : 245 / 薬物数 : 318 - (DrugBank : 86) / 標的遺伝子数 : 44 - 標的パスウェイ数 : 166
薬物ごとの開発者(Primary Sponsor)、臨床試験情報(抜粋)です。
00070500
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
00319301
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)
Center for International Blood and Marrow Transplant Research
2011 - NCT01351545 United States;
AD-MSC transdifferentiated HSCs (AD-HSCs)
Navy General Hospital, Beijing
2015 Phase 1/Phase 2 NCT02407470 China;
AMG531
Kyowa Hakko Kirin Co., Ltd.
2016 Phase 2-3 JPRN-JapicCTI-163243 -
Kyowa Kirin Co., Ltd
2019 Phase 2-3 JPRN-JapicCTI-194962 Japan, Asia except Japan;
2019 Phase 2-3 JPRN-JapicCTI-194746 Japan, Asia except Japan;
Kyowa Kirin Korea Co., Ltd.
2014 Phase 2 NCT02094417 Korea, Republic of;
AMPHOTERICINE B, LIPOSOME
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
AP1903
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
2017 Phase 1;Phase 2 EUCTR2016-003226-16-IT Italy;
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom;
AP1903 A594
Bellicum Pharmaceuticals, Inc.
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
ATG
Chinese Academy of Medical Sciences
2010 Phase 4 NCT01997372 China;
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00001964 United States;
University of Illinois at Chicago
2000 - NCT01499147 United States;
ATG+Rapamune+cyclosporine
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00061360 United States;
ATG+cyclosporine
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00061360 United States;
ATGAM plus CsA with or without Eltrombopag
European Society for Blood and Marrow Transplantation
2021 - NCT05049668 France;
Abatacept
Emory University
2014 Phase 1 NCT01917708 United States;
Adipose derived mesenchymal stem cells ( AD-MSCs)
Navy General Hospital, Beijing
2015 Phase 1/Phase 2 NCT02407470 China;
Alefacept
Emory University
2010 - NCT01319851 United States;
The Cleveland Clinic
2011 Phase 1 NCT01267643 United States;
Alemtuzumab
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
Federico II University
2006 Phase 2 NCT00895739 Italy;
GCP-ISS HE0403 group
2004 Phase 1,2 JPRN-C000000356 Japan;
M.D. Anderson Cancer Center
2010 Phase 2 NCT01191749 United States;
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00260689 United States;
UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
2007 - EUCTR2008-001151-22-IT Italy;
Alemtuzumab (Campath )
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00195624 United States;
Alemtuzumab and Rituximab
Hospital Universitario Dr. Jose E. Gonzalez
2011 - NCT01408342 Mexico;
Alkeran
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Allogeneic Bone Marrow Transplantation
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Allogeneic Hematopoietic Stem Cell Transplantation
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03192397 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
Allogeneic bone marrow transplantation
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Allogeneic donor derived B-lymphocytes
University of Erlangen-Nürnberg Medical School
2013 Phase 1/Phase 2 NCT02007811 Germany;
Allogeneic hematopoietic stem cell transplantation
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2009 - NCT00856388 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Allogeneic stem cell transplant
St. Jude Children's Research Hospital
2002 - NCT00186797 United States;
Allogenic Stem Cell Transplantation
Assiut University
2019 Phase 2/Phase 3 NCT03295058 -
Alpha beta depletion
Mitchell Cairo
2020 Phase 2 NCT04099966 United States;
Androgens
Shengyun Lin
2018 - NCT03218657 China;
Anti-CD45
Baylor College of Medicine
2001 Phase 1/Phase 2 NCT00590460 United States;
Anti-Thymocyte Globulin
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2012 Phase 2 NCT01624805 United States;
Anti-Thymocyte Globulin (Rabbit)
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
Anti-human T-lymphocyte immunoglobulin from horse
Pfizer Inc.
- Phase 3 EUCTR2021-002155-11-Outside-EU/EEA Japan;
Anti-human immunoglobulin, equine
Pfizer Inc.
- Phase 3 EUCTR2021-002155-11-Outside-EU/EEA Japan;
Anti-thymocyte globulin
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
2000 Phase 2 NCT00006379 United States;
1998 Phase 2 NCT00003336 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Roswell Park Cancer Institute
2009 - NCT00856388 United States;
2002 Phase 2 NCT00053989 United States;
1998 Phase 3 NCT00004474 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
The Cleveland Clinic
2005 Phase 2 NCT01231841 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Anti-thymocyte globulin (horse)
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00260689 United States;
Anti-thymocyte globulin (rabbit)
EBMT (European Group for Blood and Marrow Transplantation)
2009 - EUCTR2007-000902-55-DE France;Germany;United Kingdom;
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00260689 United States;
Antilymphocyte serum
National Heart, Lung, and Blood Institute (NHLBI)
1982 Phase 3 NCT00000597 -
Antithymocyte Globulin
M.D. Anderson Cancer Center
2006 Phase 1/Phase 2 NCT00474747 United States;
2000 - NCT00427336 United States;
Antithymocyte Globulin (ATG)
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Antithymocyte globulin
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
National Heart, Lung, and Blood Institute (NHLBI)
1997 Phase 2 NCT00001626 United States;
Antithymocyte globulin (Rabbit)
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Antiviral therapy
City of Hope Medical Center
2010 - NCT01199562 United States;
Apheresis
National Heart, Lung, and Blood Institute (NHLBI)
2001 Phase 1 NCT00011830 United States;
Assessment of therapy complications
Vanderbilt University
2009 - NCT00993694 United States;
Atgam
Pfizer Inc.
- Phase 3 EUCTR2021-002155-11-Outside-EU/EEA Japan;
Avatrombopag
Peking Union Medical College Hospital
2021 Phase 2/Phase 3 NCT04728789 China;
BL-8040
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
BPX-501 cells
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom;
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
Bone Marrow Transplant
M.D. Anderson Cancer Center
2006 Phase 1/Phase 2 NCT00474747 United States;
Bone marrow ablation with stem cell support
Case Comprehensive Cancer Center
1998 Phase 2 NCT00003336 United States;
Bone marrow aspiration
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
Bone marrow derived mesenchymal stem cells
Guangzhou General Hospital of Guangzhou Military Command
2011 Phase 1/Phase 2 NCT01305694 China;
Bone marrow transplant
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2014 Phase 2 NCT02224872 United States;
Bone marrow transplantation
Roswell Park Cancer Institute
1998 Phase 3 NCT00004474 United States;
Busilvex
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Busulfan
Case Comprehensive Cancer Center
1998 Phase 2 NCT00003336 United States;
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine
2017 Phase 0 ChiCTR1900023509 China;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Busulfan, fludarabine, & cyclophosphamide with immunosuppression with ATG and cyclosporine.
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States;
Busulfan/Fludarabine phosphate/Tacrolimus/Methotrexate/G-CSF
University of California, San Francisco
2002 Phase 2 NCT00516152 United States;
CAMPATH-1H
Baylor College of Medicine
2001 Phase 1/Phase 2 NCT00590460 United States;
CAMPATH-1H (Alemtuzumab)
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
CASPOFUNGIN ACETATE
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
CD3-depleted hematopoietic cell transplantation
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
CD34 Stem Cell Selection Therapy
Diane George
2013 Phase 1/Phase 2 NCT01966367 United States;
CD3±CD19 depleted hematopoietic stem cell transplantation
Asan Medical Center
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
CD45RA-depleted DLI
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
CD62L- Tem
University College, London
2019 Phase 1 NCT03836690 United Kingdom;
CEFEPIME DIHYDROCHLORIDE MONOHYDRATE
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
CYCLOPHOSPHAMIDE MONOHYDRATE
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Campath
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
Campath 1H
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Campath, Chemo and/or TBI Allo SCT
David Rizzieri, MD
1999 Phase 2 NCT00004143 United States;
Campath-1H
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00065260 United States;
Carboplatin
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Carmustine
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Chelation
Novartis Pharmaceuticals
2014 Phase 4 NCT01818726 Russian Federation;
Chemotherapy
Vanderbilt University
2009 - NCT00993694 United States;
Chinese herbal concoction twice a day for 6 months
Singapore General Hospital
2009 Phase 1/Phase 2 NCT01224496 Singapore;
Ciclosporin
Institute of Hematology & Blood Disease Hospital Chinese Academy of Medical Sciences
2021 Phase 0 ChiCTR2100045322 China;
Jiangsu Province Hospital
2020 Phase 4 ChiCTR2100045895 China;
Ciclosporin Soft Capsule
Jiangsu HengRui Medicine Co., Ltd.
2020 Phase 1 NCT05088174 China;
Ciclosporine
Blood Diseases Hospital, Chinese Academy of Medical Sciences
2015 Phase 1 study ChiCTR-IPR-14005720 China;
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
CliniMACS
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
CliniMACS device
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States;
Clofarabine
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Cohort 1: hATG, CsA, EPAG Day 14 to Month 6
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
Cohort 2: hATG, CsA, EPAG Day 14 to Month 3
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
Cohort 3: hATG, CsA (dose reduced), EPAG day 1 to month 6
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
Combination of thrombopoietin mimetic and cyclosporin A
Safaa AA Khaled
2019 Phase 4 NCT03896971 Egypt;
Cord Blood Infusion
University of Rochester
2015 Phase 1 NCT03016806 United States;
Cord Blood Transplant
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01553461 United States;
Cord Blood Units
National Heart, Lung, and Blood Institute (NHLBI)
2015 Phase 2 NCT01861093 United States;
Cord blood
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2016 Phase 4 NCT02745717 China;
CordIn
National Heart, Lung, and Blood Institute (NHLBI)
2017 Phase 1/Phase 2 NCT03173937 United States;
Creatinine
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
CsA
Cooperative study between the West Japan Hematology Study Group and Clinical Research Support Center Kyushu
2017 - JPRN-UMIN000030453 Japan;
European Group for Blood and Marrow Transplantation
2015 Phase 3 NCT02099747 France;Germany;Italy;Netherlands;Spain;Switzerland;United Kingdom;
Henan Province Cancer Hospital
2017 - ChiCTR-IOR-17012957 China;
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
Jiangsu Province Hospital
2020 Phase 4 ChiCTR2100045895 China;
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00065260 United States;
Novartis Pharmaceuticals
2017 Phase 2 NCT03025698 Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2015 Phase 2 NCT02404025 Japan;
The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)
2021 Phase 0 ChiCTR2100047288 China;
Cy
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Cy-ATG
Cooperative Study Group A for Hematology
2010 Phase 3 NCT01145976 Korea, Republic of;
Cyclophosphamide
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
1999 Phase 2 NCT00636909 -
Cancer Hospital Affiliated to Zhengzhou University-He'nan Cancer Hospital
2019 Phase 0 ChiCTR1900026462 China;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
2000 Phase 2 NCT00006379 United States;
1998 Phase 2 NCT00003336 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Kanto Study Group for Cell Therapy
2011 Phase 2 JPRN-UMIN000006071 Japan;
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2017 Phase 1 NCT02960646 United States;
2006 Phase 1/Phase 2 NCT00474747 United States;
2000 - NCT00427336 United States;
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
2007 Phase 2/Phase 3 NCT00455312 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
2006 Phase 1/Phase 2 NCT00326417 United States;
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
1995 Phase 2 NCT00002718 United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2019 Phase 2 NCT03520647 United States;
2010 Phase 1/Phase 2 NCT01193283 United States;
2010 Phase 1/Phase 2 NCT01187017 United States;
1997 Phase 2 NCT00001626 United States;
Northside Hospital, Inc.
2016 Phase 2 NCT02828592 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
2017 Phase 2 NCT03192397 United States;
2002 Phase 2 NCT00053989 United States;
1998 Phase 3 NCT00004474 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2010 Phase 2 NCT01350245 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
1996 Phase 2 NCT00004464 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of Alabama at Birmingham
2013 Phase 2 NCT02065154 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Xiangya Hosptial of Central South University
2017 - ChiCTR-ONC-17012896 China;
Cyclophosphamide (CY)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Cyclophosphamide (CY) (Plan 1)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Cyclophosphamide (CY) (Plan 2)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Cyclophosphamide, Fludarabine, Rabbit ATG
City of Hope Medical Center
2009 - NCT01129323 United States;
Cyclophosphamide, Fludarabine, Thymoglobulin
The Korean Society of Pediatric Hematology Oncology
2008 Phase 2 NCT00882323 Korea, Republic of;
Cyclophosphamide, fludarabine , thymoglobulin
The Korean Society of Pediatric Hematology Oncology
2006 Phase 2 NCT00737685 Korea, Republic of;
Cyclophosphamide,Campath IH and TBI
Mayo Clinic
2007 Phase 1 NCT00578266 United States;
Cyclophosphamide,cyclosporine A
Xiaofan Zhu
2012 Phase 4 NCT01995331 China;
Cyclosporin
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
The First Affiliated Hospital of Zhengzhou University
2016 - ChiCTR-IOR-16008738 China;
Cyclosporin A
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
Peking Union Medical College Hospital
2020 Phase 2 NCT04403321 China;
Shandong University
2010 Phase 2 NCT01182662 China;
Cyclosporine
Beth Israel Deaconess Medical Center
1999 Phase 2 NCT00636909 -
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
Cooperative study between the West Japan Hematology Study Group and Clinical Research Support Center Kyushu
2017 - JPRN-UMIN000030453 Japan;
Federico II University
2006 Phase 2 NCT00895739 Italy;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences
2021 Phase 2 ChiCTR2100043229 China;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences
2019 Phase 0 ChiCTR1900027553 China;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College
2021 Phase 4 ChiCTR2000041485 China;
Jinhua people's Hospital
2015 Phase 2-3 ChiCTR1900028153 -
M.D. Anderson Cancer Center
2012 Phase 2 NCT01624805 United States;
2005 Phase 2 NCT00806598 United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2020 Phase 2 NCT04304820 United States;
2010 Phase 1/Phase 2 NCT01193283 United States;
2005 Phase 2 NCT00260689 United States;
2005 Phase 2 NCT00195624 United States;
2000 Phase 2 NCT00005935 United States;
1997 Phase 2 NCT00001626 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Novartis Pharmaceuticals
2017 Phase 2 NCT02998645 Brazil;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
Office of Rare Diseases (ORD)
2006 Phase 1/Phase 2 NCT00319878 United States;
The Cleveland Clinic
2005 Phase 2 NCT01231841 United States;
Cyclosporine (Gengraf )
National Heart, Lung, and Blood Institute (NHLBI)
2009 Phase 2 NCT00944749 United States;
Cyclosporine A
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00001964 United States;
Cyclosporine A (CsA)
Novartis Pharmaceuticals
2020 Phase 2 NCT04328727 China;Japan;Korea, Republic of;Taiwan;
Cyclosporine Oral Product
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2016 Phase 4 NCT02745717 China;
Cyclosporins
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
Shengyun Lin
2018 - NCT03218657 China;
Cytarabine
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)
2021 Phase 0 ChiCTR2100047288 China;
Cytokine-treated Veto Cells
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
Cytoxan
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
DNA analysis
City of Hope Medical Center
2010 - NCT01199562 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
Daclizumab
Neal Young, M.D.
1999 Phase 2 NCT00001962 United States;
Danazol
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences
2019 Phase 0 ChiCTR1900027553 China;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College
2021 Phase 4 ChiCTR2000041485 China;
National Heart, Lung, and Blood Institute (NHLBI)
2011 Phase 1/Phase 2 NCT01441037 United States;
Dapsone
Vanderbilt University
2009 - NCT00993694 United States;
Decitabine
Institute of Hematology & Blood Diseases Hospital
2021 Phase 2 NCT04854889 China;
The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)
2021 Phase 0 ChiCTR2100047288 China;
Desferasirox
Novartis Pharmaceuticals
2011 Phase 4 NCT01546415 China;
Dextrose
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
Donor Lymphocyte Infusion
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
Donor Lymphocyte Infusion (DLI)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
2010 Phase 2 NCT01350245 United States;
Donor mobilized PBSC infusion
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
EDTA
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
ELTROMBOPAG OLAMINE
Universitätsklinikum Ulm
2015 Phase 2;Phase 3 EUCTR2014-000174-19-DE France;Germany;Italy;Netherlands;Switzerland;
ENBREL*SC 4FL 25MG+4SIR 1ML
ISTITUTO GIANNINA GASLINI
2009 - EUCTR2009-012746-23-IT Italy;
2005 - EUCTR2004-004914-18-IT Italy;
ETB115
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
Novartis Farmacéutica, S.A
2017 Phase 2 EUCTR2016-002814-29-ES Brazil;Canada;France;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Qatar;Spain;Turkey;
Novartis Pharma AG
2019 Phase 2 EUCTR2015-003166-91-GB Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2018 Phase 2 EUCTR2015-003166-91-NL Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2017 Phase 2 EUCTR2016-002814-29-NL Brazil;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
2017 Phase 2 EUCTR2016-002814-29-HU Brazil;France;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Turkey;
2017 Phase 2 EUCTR2015-003166-91-PT Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
Early retreatment with ATG
European Group for Blood and Marrow Transplantation
2001 Phase 3 NCT01163942 Czech Republic;France;Germany;Greece;Italy;Netherlands;Sweden;Switzerland;United Kingdom;
Eltrombopag
Assiut University
2017 Phase 4 NCT03243656 Egypt;
B. Höchsmann
2015 Phase 2/Phase 3 NCT02773225 Germany;
European Group for Blood and Marrow Transplantation
2015 Phase 3 NCT02099747 France;Germany;Italy;Netherlands;Spain;Switzerland;United Kingdom;
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
2016 Phase 3 NCT03413306 Russian Federation;
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
National Heart, Lung, and Blood Institute (NHLBI)
2020 Phase 2 NCT04304820 United States;
2013 Phase 2 NCT01891994 United States;
2011 Phase 2 NCT01328587 United States;
2009 Phase 2 NCT00922883 United States;
Novartis Pharmaceuticals
2020 Phase 2 NCT04328727 China;Japan;Korea, Republic of;Taiwan;
2019 Phase 2 NCT03988608 China;
2017 Phase 2 NCT03025698 Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2017 Phase 2 NCT02998645 Brazil;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
2015 Phase 2 NCT02404025 Japan;
2014 Phase 2 NCT02148133 Japan;
University of Utah
2012 Phase 2 NCT01703169 United States;
Etanercept
ISTITUTO GIANNINA GASLINI
2009 - EUCTR2009-012746-23-IT Italy;
2005 - EUCTR2004-004914-18-IT Italy;
Etoposide
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Extension Cohort
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
FK-506
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
FLUDARABINE PHOSPHATE
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Filgrastim
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
2012 Phase 2 NCT01624805 United States;
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
1996 Phase 2 NCT00004464 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Flu-ATG
Cooperative Study Group A for Hematology
2010 Phase 3 NCT01145976 Korea, Republic of;
Fludarabine
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Baylor College of Medicine
2001 Phase 1/Phase 2 NCT00590460 United States;
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
1999 Phase 2 NCT00636909 -
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
GCP-ISS HE0403 group
2004 Phase 1,2 JPRN-C000000356 Japan;
Kanto Study Group for Cell Therapy
2011 Phase 2 JPRN-UMIN000006071 Japan;
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2006 Phase 1/Phase 2 NCT00474747 United States;
2000 - NCT00427336 United States;
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
2007 Phase 2/Phase 3 NCT00455312 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
2006 Phase 1/Phase 2 NCT00326417 United States;
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2010 Phase 1/Phase 2 NCT01187017 United States;
Northside Hospital, Inc.
2016 Phase 2 NCT02828592 United States;
Peking University People's Hospital
2018 - NCT03821987 China;
Seoul National University Hospital
2011 Phase 2 NCT01472055 Korea, Republic of;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2011 Phase 2 NCT01384513 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Fludarabine (FLU)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Fludarabine Phosphate
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
2017 Phase 2 NCT03192397 United States;
Fludarabine phosphate
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
2000 Phase 2 NCT00006379 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2009 - NCT00856388 United States;
2002 Phase 2 NCT00053989 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Fludarabine, Cyclophosphamide
St. Jude Children's Research Hospital
2002 - NCT00186797 United States;
Fludarabine/ melphalan
University of Illinois at Chicago
2000 - NCT01499147 United States;
Fludarabine/busulfan
University of Illinois at Chicago
2000 - NCT01499147 United States;
Foscarnet
The First Affiliated Hospital of Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2000031933 China;
Foscarnet sodium
City of Hope Medical Center
2010 - NCT01199562 United States;
G-CSF
Beth Israel Deaconess Medical Center
1999 Phase 2 NCT00636909 -
European Group for Blood and Marrow Transplantation
2001 Phase 3 NCT01163942 Czech Republic;France;Germany;Greece;Italy;Netherlands;Sweden;Switzerland;United Kingdom;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences
2019 Phase 0 ChiCTR1900027553 China;
M.D. Anderson Cancer Center
2005 Phase 2 NCT00806598 United States;
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2010 Phase 2 NCT01174108 United States;
2001 Phase 1 NCT00011830 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
GM-CSF
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
GVHD Prophylaxis
Assiut University
2019 Phase 2/Phase 3 NCT03295058 -
Ganciclovir
City of Hope Medical Center
2010 - NCT01199562 United States;
Graft-versus-tumor induction therapy
Case Comprehensive Cancer Center
2000 Phase 2 NCT00006379 United States;
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
H-ATG (ATGAM )
National Heart, Lung, and Blood Institute (NHLBI)
2009 Phase 2 NCT00944749 United States;
HATG
European Group for Blood and Marrow Transplantation
2015 Phase 3 NCT02099747 France;Germany;Italy;Netherlands;Spain;Switzerland;United Kingdom;
Novartis Pharmaceuticals
2017 Phase 2 NCT03025698 Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
HPC, A Infusion
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
HUMAN IGG4 ISOTYPE MONOCLONAL (IL2-RG) ANTIBODY
Regeneron Pharmaceuticals, Inc.
2020 Phase 1;Phase 2 EUCTR2020-002031-29-GB France;Korea, Republic of;United Kingdom;United States;
2020 Phase 1;Phase 2 EUCTR2020-002031-29-FR France;Korea, Republic of;United Kingdom;United States;
Haplo HSCT
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Haplo/cord transplant
Joanne Kurtzberg, MD
2007 Phase 1/Phase 2 NCT00673114 United States;
Haploidentical HSCT using TBI free regimen, ''ATG'' with ''Post transplant cyclophosphamide''
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan
2018 Phase 2 NCT03955601 Pakistan;
Haploidentical Hematopoietic Cell Transplantation
Johns Hopkins All Children's Hospital
2020 Phase 2 NCT04356469 United States;
Hematopoietic Cell Transplantation
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
Hematopoietic stem cell transplantation (HSCT)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2010 Phase 2 NCT01350245 United States;
Heparin
Alberta Children's Hospital
2011 Phase 3 NCT01343680 Canada;
Hetrombopag
Peking Union Medical College Hospital
2021 Phase 2/Phase 3 NCT05018936 China;
Hetrombopag Olamine
Jiangsu HengRui Medicine Co., Ltd.
2019 Phase 3 NCT04961710 China;
2018 Phase 1/Phase 2 NCT03557099 China;
Hetrombopag Olamine Tablet
Jiangsu HengRui Medicine Co., Ltd.
2021 Phase 1 NCT05088655 China;
2020 Phase 1 NCT05088642 China;
2020 Phase 1 NCT05088174 China;
Hetrombopag Olamine+Standard Therapy
Jiangsu HengRui Medicine Co., Ltd.
2019 Phase 3 NCT03825744 China;
Horse anti-thymocyte globulin (ATG)
Michael Pulsipher, MD
2016 - NCT02845596 United States;
Horse anti-thymocyte globulin (hATG)
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
Horse-Anti-thymocyte-Globulin
National Heart, Lung, and Blood Institute (NHLBI)
2020 Phase 2 NCT04304820 United States;
Human Placental Derived Stem Cell
New York Medical College
2013 Phase 1 NCT01586455 United States;
ICL670
Novartis Pharmaceuticals
2014 Phase 4 NCT01818726 Russian Federation;
IST (ATG + CsA)
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
2016 Phase 3 NCT03413306 Russian Federation;
Ibrutinib
Jennifer Woyach
2020 Phase 2 NCT04439006 United States;
Imipenem / cilastatine
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
Imipenem-cilastatine
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
Immunosuppressive Therapy (IST)
Michael Pulsipher, MD
2016 - NCT02845596 United States;
In vitro-treated bone marrow transplantation
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
In vitro-treated peripheral blood stem cell transplantation
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Infection prophylaxis and management
City of Hope Medical Center
2010 - NCT01199562 United States;
Intravenous bone marrow mesenchymal stem cells infusion
University of Sao Paulo
2011 Phase 1/Phase 2 NCT01297972 Brazil;
Itacitinib
Incyte Corporation
2019 - NCT03906318 -
Levamisole
The First affiliated Hospital of Zhejiang Chinese Medical University
2017 - ChiCTR-IOR-17011653 China;
Levamisole hydrochloride
Shengyun Lin
2018 - NCT03218657 China;
Levamisole+cyclosporin A+Glucocorticoids
Institute of Hematology & Blood Diseases Hospital
2013 Phase 2 NCT01760096 China;
2012 Phase 2 NCT01642979 China;
Lo-Ovral Oral Contraceptive Pills
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2007 Phase 1/Phase 2 NCT00556400 United States;
MMF
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00001964 United States;
MPA
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
MSC
CHU Sart-Tilman
2009 Phase 3 EUCTR2008-005594-35-BE Belgium;
MSC+ATG
Chinese Academy of Medical Sciences
2013 Phase 4 NCT02218437 China;
MTX
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Management of therapy complications
City of Hope Medical Center
2010 - NCT01199562 United States;
Mannitol
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
Matched Unrelated Donor Hematopoietic Stem Cell Transplant
Michael Pulsipher, MD
2016 - NCT02845596 United States;
Melphalan
Case Comprehensive Cancer Center
1998 Phase 2 NCT00003336 United States;
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2009 - NCT00856388 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Melphalan Hydrochloride
Roswell Park Cancer Institute
2017 Phase 2 NCT03192397 United States;
Mesenchymal stem cells
CHU Sart-Tilman
2009 Phase 3 EUCTR2008-005594-35-BE Belgium;
Guangzhou General Hospital of Guangzhou Military Command
2013 Phase 2 NCT02247973 China;
Hebei Medical University
2017 Phase 1 NCT03055078 China;
Mesna
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2014 Phase 2 NCT02224872 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Metformin
Department of Hematology, Second Medical Center, Chinese PLA General Hospital
2020 Phase 2 ChiCTR2000028833 China;
Methotrexate
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
Beth Israel Deaconess Medical Center
1999 Phase 2 NCT00636909 -
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Xiangya Hosptial of Central South University
2017 - ChiCTR-ONC-17012896 China;
Methylprednisolone
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
1998 Phase 2 NCT00003336 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
M.D. Anderson Cancer Center
2012 Phase 2 NCT01624805 United States;
2005 Phase 2 NCT00806598 United States;
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
Methylprednisolone (MP)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Miltenyi CD34 Reagent System
National Heart, Lung, and Blood Institute (NHLBI)
2010 Phase 2 NCT01174108 United States;
Muromonab-CD3
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Mycophenolate Mofetil (MMF)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2010 Phase 2 NCT01350245 United States;
Mycophenolate mofetil
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00005935 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2002 Phase 2 NCT00053989 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2011 Phase 2 NCT01384513 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Mycophenolate mofetil (MMF)
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Mycophenolic acid
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
Mycophenolic acid mofetil
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2014 Phase 2 NCT02224872 United States;
Nandrolone
National Heart, Lung, and Blood Institute (NHLBI)
1982 Phase 3 NCT00000597 -
Neoral
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
Non ATG Conditioning regimen
Assiut University
2019 Phase 2/Phase 3 NCT03295058 -
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
Nonmyeloablative allogeneic hematopoietic stem cell transplantation
University of California, San Francisco
2005 - NCT00295997 United States;
Normal saline
Alberta Children's Hospital
2011 Phase 3 NCT01343680 Canada;
Noxafil Gastro resistant tablets
King's College Hospital NHS Foundation Trust
2016 Phase 4 EUCTR2016-001223-31-GB United Kingdom;
Noxafil®
King's College Hospital NHS Foundation Trust
2016 Phase 4 EUCTR2016-001223-31-GB United Kingdom;
Obatoclax mesylate (GX15-070MS)
Gemin X
2005 Phase 1 NCT00438178 Canada;United States;
PF-06462700
Pfizer
2020 Phase 3 NCT04350606 Japan;
Pegfilgrastim
M.D. Anderson Cancer Center
2012 Phase 2 NCT01624805 United States;
Peripheral Blood Stem Cell Transplantation
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2017 Phase 1 NCT02960646 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
Peripheral blood stem cell transplantation
Case Comprehensive Cancer Center
2000 Phase 2 NCT00006379 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Peripheral blood stem cell transplantation (PBSCT)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Posaconazole
King's College Hospital NHS Trust
2016 Phase 4 NCT02875743 United Kingdom;
Seoul National University Hospital
2018 Phase 2 NCT03318159 Korea, Republic of;
Prednisolone
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
Prograf
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
R-ATG
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00065260 United States;
RABBIT HUMAN T LYMPHOCYTE IMMUNOGLOBULIN
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
RATG
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
REGN7257
Regeneron Pharmaceuticals
2021 Phase 1/Phase 2 NCT04409080 France;Korea, Republic of;United Kingdom;United States;
Regeneron Pharmaceuticals, Inc.
2020 Phase 1;Phase 2 EUCTR2020-002031-29-GB France;Korea, Republic of;United Kingdom;United States;
2020 Phase 1;Phase 2 EUCTR2020-002031-29-FR France;Korea, Republic of;United Kingdom;United States;
REVOLADE - 25 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER(PA/ALU/PVC/ALU) 28 COMPRESSE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
REVOLADE - 50 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER(PA/ALU/PVC/ALU
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
RNA analysis
City of Hope Medical Center
2010 - NCT01199562 United States;
RVG 101614
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
RVG 105155
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
Rabbit ATG
Northside Hospital, Inc.
2016 Phase 2 NCT02828592 United States;
Novartis Pharmaceuticals
2015 Phase 2 NCT02404025 Japan;
Rabbit ATG, (Genzyme)
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Rabbit ATG, Cyclosporine, Levamisole
Yizhou Zheng
2014 Phase 2 NCT02203396 China;
Rabbit ATG, Thymoglobuline (Genzyme)
King Faisal Specialist Hospital & Research Center
2008 Phase 2 NCT01530555 -
Rabbit anti-thymocyte globulin (ATG)
Michael Pulsipher, MD
2016 - NCT02845596 United States;
Rabbit anti-thymocyte globulin (r-ATG)
Novartis Pharmaceuticals
2020 Phase 2 NCT04328727 China;Japan;Korea, Republic of;Taiwan;
Rabbit antithymocyte globulin
European Group for Blood and Marrow Transplantation
2008 Phase 2 NCT00471848 France;Germany;Italy;Saudi Arabia;Switzerland;United Kingdom;
Rabbit antithymoglobulin (ATG)
Navy General Hospital, Beijing
2015 Phase 1/Phase 2 NCT02407470 China;
Rapamune
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Rapamycin
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Recombinant Methionyl Human Stem Cell Factor (r-metHuSCF)
National Heart, Lung, and Blood Institute (NHLBI)
1993 Phase 1 NCT00001398 United States;
Revolade
European Society for Blood and Marrow Transplantation
2015 - EUCTR2014-000363-40-ES Spain;
Universitätsklinikum Ulm
2015 Phase 2;Phase 3 EUCTR2014-000174-19-DE France;Germany;Italy;Netherlands;Switzerland;
RhTPO
Institute of Hematology, People's Hospital, Peking University
2019 - ChiCTR1800019669 China;
Tianjin Medical University General Hospital
2016 Phase 2 NCT02857530 China;
Rimiducid
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
Rituxan
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Rituximab
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00229619 United States;
Rivogenlecleucel
Bellicum Pharmaceuticals, Inc.
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
Rivogenleucleucel
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
Romiplostim
Anjali Sharathkumar
2020 Early Phase 1 NCT04478227 United States;
Kyowa Hakko Kirin Co., Ltd.
2016 Phase 2-3 JPRN-JapicCTI-163243 -
Kyowa Kirin Co., Ltd
2019 Phase 2-3 JPRN-JapicCTI-194962 Japan, Asia except Japan;
2019 Phase 2-3 JPRN-JapicCTI-194746 Japan, Asia except Japan;
Kyowa Kirin Co., Ltd.
2019 Phase 2/Phase 3 NCT04095936 Japan;
2019 Phase 2/Phase 3 NCT03957694 Japan;
2016 Phase 2/Phase 3 NCT02773290 Japan;Korea, Republic of;
SA
The First affiliated Hospital of Zhejiang Chinese Medical University
2017 - ChiCTR-IOR-17011653 China;
SANDIMMUN NEORAL - 10 MG CAPSULE MOLLI 50 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SANDIMMUN NEORAL - 100 MG CAPSULE MOLLI 30 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SANDIMMUN NEORAL - 25 MG CAPSULE MOLLI 50 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SANDIMMUN NEORAL - 50 MG CAPSULE MOLLI 50 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SB497115
Universitätsklinikum Ulm
2015 Phase 2;Phase 3 EUCTR2014-000174-19-DE France;Germany;Italy;Netherlands;Switzerland;
SODIUM CHLORIDE SOLUTION
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
SULFAMETH
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
Sandimmun Neoral
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Sargramostim
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
2002 - NCT00053157 United States;
Sirolimus
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2016 Phase 2 NCT02979873 United States;
Office of Rare Diseases (ORD)
2006 Phase 1/Phase 2 NCT00319878 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03192397 United States;
Sodium chloride
EBMT (European group for Blood and Marrow Transplantation)
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
Standard Vitamin D3 Supplementation
Phoenix Children's Hospital
2017 Phase 4 NCT03176849 United States;
Standard therapy of septic shock
National Research Center for Hematology, Russia
2012 Phase 1/Phase 2 NCT01849237 Russian Federation;
Stanozolol
The First Affiliated Hospital of Zhengzhou University
2016 - ChiCTR-IOR-16008738 China;
Stem Cell Transplant
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
Stem Cell Transplantation
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Stem cell infusion
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
2001 Phase 1/Phase 2 NCT00590460 United States;
T Cell-Depleted Donor Lymphocyte Infusion
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
TRIMETHOPRIM SULFATE
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
Tacrolimus
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Peking Union Medical College Hospital
2020 Phase 2 NCT04403321 China;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2002 Phase 2 NCT00053989 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2011 Phase 2 NCT01384513 United States;
2010 Phase 2 NCT01350245 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Testosterone undecanoate
Jinhua people's Hospital
2015 Phase 2-3 ChiCTR1900028153 -
Therapeutic allogeneic lymphocytes
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Thiotepa
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Thymoglobulin
Kanto Study Group for Cell Therapy
2011 Phase 2 JPRN-UMIN000006071 Japan;
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
M.D. Anderson Cancer Center
2005 Phase 2 NCT00806598 United States;
Nagoya University
2012 Phase 3 NCT01844635 Japan;
2012 - JPRN-UMIN000011134 Japan,Asia(except Japan);
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2016 Phase 4 NCT02745717 China;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
Thymoglobuline®/Thymoglobulin®
EBMT (European Group for Blood and Marrow Transplantation)
2009 - EUCTR2007-000902-55-DE France;Germany;United Kingdom;
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
Total Body Irradiation
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Total Body Irradiation (TBI) (Plan 1)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Umbilical Cord Blood
National Heart, Lung, and Blood Institute (NHLBI)
2008 Phase 2 NCT00604201 United States;
Umbilical Cord Blood After Myeloablative Conditioning
Tufts Medical Center
2005 Phase 2 NCT00676806 United States;
Umbilical Cord Blood After Reduced-Intensity Conditioning
Tufts Medical Center
2005 Phase 2 NCT00676806 United States;
Umbilical Cord Blood Transplantation
New York Blood Center
1993 Early Phase 1 NCT00212407 United States;
Umbilical cord blood transplantation
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
1998 Phase 2 NCT00003336 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
Valganciclovir
City of Hope Medical Center
2010 - NCT01199562 United States;
Voriconazole
Institute of Hematology & Blood Diseases Hospital, CAMS & PUMC
2013 - ChiCTR-PRC-13003130 China;
polymerase chain reaction
City of Hope Medical Center
2010 - NCT01199562 United States;
polymorphism analysis
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
protein expression analysis
City of Hope Medical Center
2010 - NCT01199562 United States;
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
00319301
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)
Center for International Blood and Marrow Transplant Research
2011 - NCT01351545 United States;
AD-MSC transdifferentiated HSCs (AD-HSCs)
Navy General Hospital, Beijing
2015 Phase 1/Phase 2 NCT02407470 China;
AMG531
Kyowa Hakko Kirin Co., Ltd.
2016 Phase 2-3 JPRN-JapicCTI-163243 -
Kyowa Kirin Co., Ltd
2019 Phase 2-3 JPRN-JapicCTI-194962 Japan, Asia except Japan;
2019 Phase 2-3 JPRN-JapicCTI-194746 Japan, Asia except Japan;
Kyowa Kirin Korea Co., Ltd.
2014 Phase 2 NCT02094417 Korea, Republic of;
AMPHOTERICINE B, LIPOSOME
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
AP1903
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
2017 Phase 1;Phase 2 EUCTR2016-003226-16-IT Italy;
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom;
AP1903 A594
Bellicum Pharmaceuticals, Inc.
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
ATG
Chinese Academy of Medical Sciences
2010 Phase 4 NCT01997372 China;
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00001964 United States;
University of Illinois at Chicago
2000 - NCT01499147 United States;
ATG+Rapamune+cyclosporine
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00061360 United States;
ATG+cyclosporine
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00061360 United States;
ATGAM plus CsA with or without Eltrombopag
European Society for Blood and Marrow Transplantation
2021 - NCT05049668 France;
Abatacept
Emory University
2014 Phase 1 NCT01917708 United States;
Adipose derived mesenchymal stem cells ( AD-MSCs)
Navy General Hospital, Beijing
2015 Phase 1/Phase 2 NCT02407470 China;
Alefacept
Emory University
2010 - NCT01319851 United States;
The Cleveland Clinic
2011 Phase 1 NCT01267643 United States;
Alemtuzumab
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
Federico II University
2006 Phase 2 NCT00895739 Italy;
GCP-ISS HE0403 group
2004 Phase 1,2 JPRN-C000000356 Japan;
M.D. Anderson Cancer Center
2010 Phase 2 NCT01191749 United States;
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00260689 United States;
UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
2007 - EUCTR2008-001151-22-IT Italy;
Alemtuzumab (Campath )
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00195624 United States;
Alemtuzumab and Rituximab
Hospital Universitario Dr. Jose E. Gonzalez
2011 - NCT01408342 Mexico;
Alkeran
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Allogeneic Bone Marrow Transplantation
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Allogeneic Hematopoietic Stem Cell Transplantation
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03192397 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
Allogeneic bone marrow transplantation
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Allogeneic donor derived B-lymphocytes
University of Erlangen-Nürnberg Medical School
2013 Phase 1/Phase 2 NCT02007811 Germany;
Allogeneic hematopoietic stem cell transplantation
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2009 - NCT00856388 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Allogeneic stem cell transplant
St. Jude Children's Research Hospital
2002 - NCT00186797 United States;
Allogenic Stem Cell Transplantation
Assiut University
2019 Phase 2/Phase 3 NCT03295058 -
Alpha beta depletion
Mitchell Cairo
2020 Phase 2 NCT04099966 United States;
Androgens
Shengyun Lin
2018 - NCT03218657 China;
Anti-CD45
Baylor College of Medicine
2001 Phase 1/Phase 2 NCT00590460 United States;
Anti-Thymocyte Globulin
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2012 Phase 2 NCT01624805 United States;
Anti-Thymocyte Globulin (Rabbit)
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
Anti-human T-lymphocyte immunoglobulin from horse
Pfizer Inc.
- Phase 3 EUCTR2021-002155-11-Outside-EU/EEA Japan;
Anti-human immunoglobulin, equine
Pfizer Inc.
- Phase 3 EUCTR2021-002155-11-Outside-EU/EEA Japan;
Anti-thymocyte globulin
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
2000 Phase 2 NCT00006379 United States;
1998 Phase 2 NCT00003336 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Roswell Park Cancer Institute
2009 - NCT00856388 United States;
2002 Phase 2 NCT00053989 United States;
1998 Phase 3 NCT00004474 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
The Cleveland Clinic
2005 Phase 2 NCT01231841 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Anti-thymocyte globulin (horse)
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00260689 United States;
Anti-thymocyte globulin (rabbit)
EBMT (European Group for Blood and Marrow Transplantation)
2009 - EUCTR2007-000902-55-DE France;Germany;United Kingdom;
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00260689 United States;
Antilymphocyte serum
National Heart, Lung, and Blood Institute (NHLBI)
1982 Phase 3 NCT00000597 -
Antithymocyte Globulin
M.D. Anderson Cancer Center
2006 Phase 1/Phase 2 NCT00474747 United States;
2000 - NCT00427336 United States;
Antithymocyte Globulin (ATG)
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Antithymocyte globulin
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
National Heart, Lung, and Blood Institute (NHLBI)
1997 Phase 2 NCT00001626 United States;
Antithymocyte globulin (Rabbit)
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Antiviral therapy
City of Hope Medical Center
2010 - NCT01199562 United States;
Apheresis
National Heart, Lung, and Blood Institute (NHLBI)
2001 Phase 1 NCT00011830 United States;
Assessment of therapy complications
Vanderbilt University
2009 - NCT00993694 United States;
Atgam
Pfizer Inc.
- Phase 3 EUCTR2021-002155-11-Outside-EU/EEA Japan;
Avatrombopag
Peking Union Medical College Hospital
2021 Phase 2/Phase 3 NCT04728789 China;
BL-8040
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
BPX-501 cells
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
2014 Phase 1;Phase 2 EUCTR2014-000584-41-IT Italy;Spain;United Kingdom;
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
Bone Marrow Transplant
M.D. Anderson Cancer Center
2006 Phase 1/Phase 2 NCT00474747 United States;
Bone marrow ablation with stem cell support
Case Comprehensive Cancer Center
1998 Phase 2 NCT00003336 United States;
Bone marrow aspiration
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
Bone marrow derived mesenchymal stem cells
Guangzhou General Hospital of Guangzhou Military Command
2011 Phase 1/Phase 2 NCT01305694 China;
Bone marrow transplant
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2014 Phase 2 NCT02224872 United States;
Bone marrow transplantation
Roswell Park Cancer Institute
1998 Phase 3 NCT00004474 United States;
Busilvex
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Busulfan
Case Comprehensive Cancer Center
1998 Phase 2 NCT00003336 United States;
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Shanghai Children's Medical Center affiliated to Shanghai Jiao Tong University School of Medicine
2017 Phase 0 ChiCTR1900023509 China;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Busulfan, fludarabine, & cyclophosphamide with immunosuppression with ATG and cyclosporine.
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States;
Busulfan/Fludarabine phosphate/Tacrolimus/Methotrexate/G-CSF
University of California, San Francisco
2002 Phase 2 NCT00516152 United States;
CAMPATH-1H
Baylor College of Medicine
2001 Phase 1/Phase 2 NCT00590460 United States;
CAMPATH-1H (Alemtuzumab)
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
CASPOFUNGIN ACETATE
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
CD3-depleted hematopoietic cell transplantation
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
CD34 Stem Cell Selection Therapy
Diane George
2013 Phase 1/Phase 2 NCT01966367 United States;
CD3±CD19 depleted hematopoietic stem cell transplantation
Asan Medical Center
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
CD45RA-depleted DLI
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
CD62L- Tem
University College, London
2019 Phase 1 NCT03836690 United Kingdom;
CEFEPIME DIHYDROCHLORIDE MONOHYDRATE
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
CYCLOPHOSPHAMIDE MONOHYDRATE
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Campath
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
Campath 1H
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Campath, Chemo and/or TBI Allo SCT
David Rizzieri, MD
1999 Phase 2 NCT00004143 United States;
Campath-1H
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00065260 United States;
Carboplatin
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Carmustine
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Chelation
Novartis Pharmaceuticals
2014 Phase 4 NCT01818726 Russian Federation;
Chemotherapy
Vanderbilt University
2009 - NCT00993694 United States;
Chinese herbal concoction twice a day for 6 months
Singapore General Hospital
2009 Phase 1/Phase 2 NCT01224496 Singapore;
Ciclosporin
Institute of Hematology & Blood Disease Hospital Chinese Academy of Medical Sciences
2021 Phase 0 ChiCTR2100045322 China;
Jiangsu Province Hospital
2020 Phase 4 ChiCTR2100045895 China;
Ciclosporin Soft Capsule
Jiangsu HengRui Medicine Co., Ltd.
2020 Phase 1 NCT05088174 China;
Ciclosporine
Blood Diseases Hospital, Chinese Academy of Medical Sciences
2015 Phase 1 study ChiCTR-IPR-14005720 China;
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
CliniMACS
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
CliniMACS device
Memorial Sloan Kettering Cancer Center
2009 Phase 2 NCT00987480 United States;
Clofarabine
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Cohort 1: hATG, CsA, EPAG Day 14 to Month 6
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
Cohort 2: hATG, CsA, EPAG Day 14 to Month 3
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
Cohort 3: hATG, CsA (dose reduced), EPAG day 1 to month 6
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
Combination of thrombopoietin mimetic and cyclosporin A
Safaa AA Khaled
2019 Phase 4 NCT03896971 Egypt;
Cord Blood Infusion
University of Rochester
2015 Phase 1 NCT03016806 United States;
Cord Blood Transplant
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01553461 United States;
Cord Blood Units
National Heart, Lung, and Blood Institute (NHLBI)
2015 Phase 2 NCT01861093 United States;
Cord blood
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2016 Phase 4 NCT02745717 China;
CordIn
National Heart, Lung, and Blood Institute (NHLBI)
2017 Phase 1/Phase 2 NCT03173937 United States;
Creatinine
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
CsA
Cooperative study between the West Japan Hematology Study Group and Clinical Research Support Center Kyushu
2017 - JPRN-UMIN000030453 Japan;
European Group for Blood and Marrow Transplantation
2015 Phase 3 NCT02099747 France;Germany;Italy;Netherlands;Spain;Switzerland;United Kingdom;
Henan Province Cancer Hospital
2017 - ChiCTR-IOR-17012957 China;
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
Jiangsu Province Hospital
2020 Phase 4 ChiCTR2100045895 China;
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00065260 United States;
Novartis Pharmaceuticals
2017 Phase 2 NCT03025698 Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2015 Phase 2 NCT02404025 Japan;
The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)
2021 Phase 0 ChiCTR2100047288 China;
Cy
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Cy-ATG
Cooperative Study Group A for Hematology
2010 Phase 3 NCT01145976 Korea, Republic of;
Cyclophosphamide
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
1999 Phase 2 NCT00636909 -
Cancer Hospital Affiliated to Zhengzhou University-He'nan Cancer Hospital
2019 Phase 0 ChiCTR1900026462 China;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
2000 Phase 2 NCT00006379 United States;
1998 Phase 2 NCT00003336 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Kanto Study Group for Cell Therapy
2011 Phase 2 JPRN-UMIN000006071 Japan;
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2017 Phase 1 NCT02960646 United States;
2006 Phase 1/Phase 2 NCT00474747 United States;
2000 - NCT00427336 United States;
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
2007 Phase 2/Phase 3 NCT00455312 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
2006 Phase 1/Phase 2 NCT00326417 United States;
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
1995 Phase 2 NCT00002718 United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2019 Phase 2 NCT03520647 United States;
2010 Phase 1/Phase 2 NCT01193283 United States;
2010 Phase 1/Phase 2 NCT01187017 United States;
1997 Phase 2 NCT00001626 United States;
Northside Hospital, Inc.
2016 Phase 2 NCT02828592 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
2017 Phase 2 NCT03192397 United States;
2002 Phase 2 NCT00053989 United States;
1998 Phase 3 NCT00004474 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2010 Phase 2 NCT01350245 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
1996 Phase 2 NCT00004464 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of Alabama at Birmingham
2013 Phase 2 NCT02065154 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Xiangya Hosptial of Central South University
2017 - ChiCTR-ONC-17012896 China;
Cyclophosphamide (CY)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Cyclophosphamide (CY) (Plan 1)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Cyclophosphamide (CY) (Plan 2)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Cyclophosphamide, Fludarabine, Rabbit ATG
City of Hope Medical Center
2009 - NCT01129323 United States;
Cyclophosphamide, Fludarabine, Thymoglobulin
The Korean Society of Pediatric Hematology Oncology
2008 Phase 2 NCT00882323 Korea, Republic of;
Cyclophosphamide, fludarabine , thymoglobulin
The Korean Society of Pediatric Hematology Oncology
2006 Phase 2 NCT00737685 Korea, Republic of;
Cyclophosphamide,Campath IH and TBI
Mayo Clinic
2007 Phase 1 NCT00578266 United States;
Cyclophosphamide,cyclosporine A
Xiaofan Zhu
2012 Phase 4 NCT01995331 China;
Cyclosporin
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
The First Affiliated Hospital of Zhengzhou University
2016 - ChiCTR-IOR-16008738 China;
Cyclosporin A
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
Peking Union Medical College Hospital
2020 Phase 2 NCT04403321 China;
Shandong University
2010 Phase 2 NCT01182662 China;
Cyclosporine
Beth Israel Deaconess Medical Center
1999 Phase 2 NCT00636909 -
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
Cooperative study between the West Japan Hematology Study Group and Clinical Research Support Center Kyushu
2017 - JPRN-UMIN000030453 Japan;
Federico II University
2006 Phase 2 NCT00895739 Italy;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences
2021 Phase 2 ChiCTR2100043229 China;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences
2019 Phase 0 ChiCTR1900027553 China;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College
2021 Phase 4 ChiCTR2000041485 China;
Jinhua people's Hospital
2015 Phase 2-3 ChiCTR1900028153 -
M.D. Anderson Cancer Center
2012 Phase 2 NCT01624805 United States;
2005 Phase 2 NCT00806598 United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2020 Phase 2 NCT04304820 United States;
2010 Phase 1/Phase 2 NCT01193283 United States;
2005 Phase 2 NCT00260689 United States;
2005 Phase 2 NCT00195624 United States;
2000 Phase 2 NCT00005935 United States;
1997 Phase 2 NCT00001626 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Novartis Pharmaceuticals
2017 Phase 2 NCT02998645 Brazil;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
Office of Rare Diseases (ORD)
2006 Phase 1/Phase 2 NCT00319878 United States;
The Cleveland Clinic
2005 Phase 2 NCT01231841 United States;
Cyclosporine (Gengraf )
National Heart, Lung, and Blood Institute (NHLBI)
2009 Phase 2 NCT00944749 United States;
Cyclosporine A
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00001964 United States;
Cyclosporine A (CsA)
Novartis Pharmaceuticals
2020 Phase 2 NCT04328727 China;Japan;Korea, Republic of;Taiwan;
Cyclosporine Oral Product
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2016 Phase 4 NCT02745717 China;
Cyclosporins
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
Shengyun Lin
2018 - NCT03218657 China;
Cytarabine
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)
2021 Phase 0 ChiCTR2100047288 China;
Cytokine-treated Veto Cells
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
Cytoxan
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
DNA analysis
City of Hope Medical Center
2010 - NCT01199562 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
2006 Phase 1 NCT00354419 United States;
Daclizumab
Neal Young, M.D.
1999 Phase 2 NCT00001962 United States;
Danazol
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences
2019 Phase 0 ChiCTR1900027553 China;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College
2021 Phase 4 ChiCTR2000041485 China;
National Heart, Lung, and Blood Institute (NHLBI)
2011 Phase 1/Phase 2 NCT01441037 United States;
Dapsone
Vanderbilt University
2009 - NCT00993694 United States;
Decitabine
Institute of Hematology & Blood Diseases Hospital
2021 Phase 2 NCT04854889 China;
The Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital)
2021 Phase 0 ChiCTR2100047288 China;
Desferasirox
Novartis Pharmaceuticals
2011 Phase 4 NCT01546415 China;
Dextrose
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
Donor Lymphocyte Infusion
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
Donor Lymphocyte Infusion (DLI)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
2010 Phase 2 NCT01350245 United States;
Donor mobilized PBSC infusion
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
EDTA
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
ELTROMBOPAG OLAMINE
Universitätsklinikum Ulm
2015 Phase 2;Phase 3 EUCTR2014-000174-19-DE France;Germany;Italy;Netherlands;Switzerland;
ENBREL*SC 4FL 25MG+4SIR 1ML
ISTITUTO GIANNINA GASLINI
2009 - EUCTR2009-012746-23-IT Italy;
2005 - EUCTR2004-004914-18-IT Italy;
ETB115
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
Novartis Farmacéutica, S.A
2017 Phase 2 EUCTR2016-002814-29-ES Brazil;Canada;France;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Qatar;Spain;Turkey;
Novartis Pharma AG
2019 Phase 2 EUCTR2015-003166-91-GB Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2018 Phase 2 EUCTR2015-003166-91-NL Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2017 Phase 2 EUCTR2016-002814-29-NL Brazil;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
2017 Phase 2 EUCTR2016-002814-29-HU Brazil;France;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Turkey;
2017 Phase 2 EUCTR2015-003166-91-PT Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
Early retreatment with ATG
European Group for Blood and Marrow Transplantation
2001 Phase 3 NCT01163942 Czech Republic;France;Germany;Greece;Italy;Netherlands;Sweden;Switzerland;United Kingdom;
Eltrombopag
Assiut University
2017 Phase 4 NCT03243656 Egypt;
B. Höchsmann
2015 Phase 2/Phase 3 NCT02773225 Germany;
European Group for Blood and Marrow Transplantation
2015 Phase 3 NCT02099747 France;Germany;Italy;Netherlands;Spain;Switzerland;United Kingdom;
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
2016 Phase 3 NCT03413306 Russian Federation;
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
National Heart, Lung, and Blood Institute (NHLBI)
2020 Phase 2 NCT04304820 United States;
2013 Phase 2 NCT01891994 United States;
2011 Phase 2 NCT01328587 United States;
2009 Phase 2 NCT00922883 United States;
Novartis Pharmaceuticals
2020 Phase 2 NCT04328727 China;Japan;Korea, Republic of;Taiwan;
2019 Phase 2 NCT03988608 China;
2017 Phase 2 NCT03025698 Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
2017 Phase 2 NCT02998645 Brazil;Hong Kong;Hungary;India;Italy;Korea, Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
2015 Phase 2 NCT02404025 Japan;
2014 Phase 2 NCT02148133 Japan;
University of Utah
2012 Phase 2 NCT01703169 United States;
Etanercept
ISTITUTO GIANNINA GASLINI
2009 - EUCTR2009-012746-23-IT Italy;
2005 - EUCTR2004-004914-18-IT Italy;
Etoposide
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Extension Cohort
National Heart, Lung, and Blood Institute (NHLBI)
2012 Phase 1/Phase 2 NCT01623167 United States;
FK-506
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
FLUDARABINE PHOSPHATE
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
Filgrastim
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
2012 Phase 2 NCT01624805 United States;
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
1996 Phase 2 NCT00004464 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Flu-ATG
Cooperative Study Group A for Hematology
2010 Phase 3 NCT01145976 Korea, Republic of;
Fludarabine
Asan Medical Center
2012 Phase 2 NCT01759732 Korea, Republic of;
2009 Phase 1/Phase 2 NCT01105273 Korea, Republic of;
Baylor College of Medicine
2001 Phase 1/Phase 2 NCT00590460 United States;
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
1999 Phase 2 NCT00636909 -
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
GCP-ISS HE0403 group
2004 Phase 1,2 JPRN-C000000356 Japan;
Kanto Study Group for Cell Therapy
2011 Phase 2 JPRN-UMIN000006071 Japan;
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2006 Phase 1/Phase 2 NCT00474747 United States;
2000 - NCT00427336 United States;
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
2007 Phase 2/Phase 3 NCT00455312 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
2006 Phase 1/Phase 2 NCT00326417 United States;
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2010 Phase 1/Phase 2 NCT01187017 United States;
Northside Hospital, Inc.
2016 Phase 2 NCT02828592 United States;
Peking University People's Hospital
2018 - NCT03821987 China;
Seoul National University Hospital
2011 Phase 2 NCT01472055 Korea, Republic of;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2011 Phase 2 NCT01384513 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Fludarabine (FLU)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Fludarabine Phosphate
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
2017 Phase 2 NCT03192397 United States;
Fludarabine phosphate
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
2000 Phase 2 NCT00006379 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2009 - NCT00856388 United States;
2002 Phase 2 NCT00053989 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Fludarabine, Cyclophosphamide
St. Jude Children's Research Hospital
2002 - NCT00186797 United States;
Fludarabine/ melphalan
University of Illinois at Chicago
2000 - NCT01499147 United States;
Fludarabine/busulfan
University of Illinois at Chicago
2000 - NCT01499147 United States;
Foscarnet
The First Affiliated Hospital of Zhejiang University School of Medicine
2020 Phase 0 ChiCTR2000031933 China;
Foscarnet sodium
City of Hope Medical Center
2010 - NCT01199562 United States;
G-CSF
Beth Israel Deaconess Medical Center
1999 Phase 2 NCT00636909 -
European Group for Blood and Marrow Transplantation
2001 Phase 3 NCT01163942 Czech Republic;France;Germany;Greece;Italy;Netherlands;Sweden;Switzerland;United Kingdom;
Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences
2019 Phase 0 ChiCTR1900027553 China;
M.D. Anderson Cancer Center
2005 Phase 2 NCT00806598 United States;
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2010 Phase 2 NCT01174108 United States;
2001 Phase 1 NCT00011830 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
GM-CSF
Beth Israel Deaconess Medical Center
2002 Phase 2 NCT00533923 United States;
GVHD Prophylaxis
Assiut University
2019 Phase 2/Phase 3 NCT03295058 -
Ganciclovir
City of Hope Medical Center
2010 - NCT01199562 United States;
Graft-versus-tumor induction therapy
Case Comprehensive Cancer Center
2000 Phase 2 NCT00006379 United States;
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
H-ATG (ATGAM )
National Heart, Lung, and Blood Institute (NHLBI)
2009 Phase 2 NCT00944749 United States;
HATG
European Group for Blood and Marrow Transplantation
2015 Phase 3 NCT02099747 France;Germany;Italy;Netherlands;Spain;Switzerland;United Kingdom;
Novartis Pharmaceuticals
2017 Phase 2 NCT03025698 Hong Kong;Netherlands;Portugal;Russian Federation;Thailand;United Kingdom;United States;
HPC, A Infusion
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
HUMAN IGG4 ISOTYPE MONOCLONAL (IL2-RG) ANTIBODY
Regeneron Pharmaceuticals, Inc.
2020 Phase 1;Phase 2 EUCTR2020-002031-29-GB France;Korea, Republic of;United Kingdom;United States;
2020 Phase 1;Phase 2 EUCTR2020-002031-29-FR France;Korea, Republic of;United Kingdom;United States;
Haplo HSCT
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Haplo/cord transplant
Joanne Kurtzberg, MD
2007 Phase 1/Phase 2 NCT00673114 United States;
Haploidentical HSCT using TBI free regimen, ''ATG'' with ''Post transplant cyclophosphamide''
National Institute of Blood and Marrow Transplant (NIBMT), Pakistan
2018 Phase 2 NCT03955601 Pakistan;
Haploidentical Hematopoietic Cell Transplantation
Johns Hopkins All Children's Hospital
2020 Phase 2 NCT04356469 United States;
Hematopoietic Cell Transplantation
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
Hematopoietic stem cell transplantation (HSCT)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2010 Phase 2 NCT01350245 United States;
Heparin
Alberta Children's Hospital
2011 Phase 3 NCT01343680 Canada;
Hetrombopag
Peking Union Medical College Hospital
2021 Phase 2/Phase 3 NCT05018936 China;
Hetrombopag Olamine
Jiangsu HengRui Medicine Co., Ltd.
2019 Phase 3 NCT04961710 China;
2018 Phase 1/Phase 2 NCT03557099 China;
Hetrombopag Olamine Tablet
Jiangsu HengRui Medicine Co., Ltd.
2021 Phase 1 NCT05088655 China;
2020 Phase 1 NCT05088642 China;
2020 Phase 1 NCT05088174 China;
Hetrombopag Olamine+Standard Therapy
Jiangsu HengRui Medicine Co., Ltd.
2019 Phase 3 NCT03825744 China;
Horse anti-thymocyte globulin (ATG)
Michael Pulsipher, MD
2016 - NCT02845596 United States;
Horse anti-thymocyte globulin (hATG)
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
Horse-Anti-thymocyte-Globulin
National Heart, Lung, and Blood Institute (NHLBI)
2020 Phase 2 NCT04304820 United States;
Human Placental Derived Stem Cell
New York Medical College
2013 Phase 1 NCT01586455 United States;
ICL670
Novartis Pharmaceuticals
2014 Phase 4 NCT01818726 Russian Federation;
IST (ATG + CsA)
Federal Research Institute of Pediatric Hematology, Oncology and Immunology
2016 Phase 3 NCT03413306 Russian Federation;
Ibrutinib
Jennifer Woyach
2020 Phase 2 NCT04439006 United States;
Imipenem / cilastatine
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
Imipenem-cilastatine
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
Immunosuppressive Therapy (IST)
Michael Pulsipher, MD
2016 - NCT02845596 United States;
In vitro-treated bone marrow transplantation
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
In vitro-treated peripheral blood stem cell transplantation
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Infection prophylaxis and management
City of Hope Medical Center
2010 - NCT01199562 United States;
Intravenous bone marrow mesenchymal stem cells infusion
University of Sao Paulo
2011 Phase 1/Phase 2 NCT01297972 Brazil;
Itacitinib
Incyte Corporation
2019 - NCT03906318 -
Levamisole
The First affiliated Hospital of Zhejiang Chinese Medical University
2017 - ChiCTR-IOR-17011653 China;
Levamisole hydrochloride
Shengyun Lin
2018 - NCT03218657 China;
Levamisole+cyclosporin A+Glucocorticoids
Institute of Hematology & Blood Diseases Hospital
2013 Phase 2 NCT01760096 China;
2012 Phase 2 NCT01642979 China;
Lo-Ovral Oral Contraceptive Pills
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2007 Phase 1/Phase 2 NCT00556400 United States;
MMF
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00001964 United States;
MPA
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
MSC
CHU Sart-Tilman
2009 Phase 3 EUCTR2008-005594-35-BE Belgium;
MSC+ATG
Chinese Academy of Medical Sciences
2013 Phase 4 NCT02218437 China;
MTX
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Management of therapy complications
City of Hope Medical Center
2010 - NCT01199562 United States;
Mannitol
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
Matched Unrelated Donor Hematopoietic Stem Cell Transplant
Michael Pulsipher, MD
2016 - NCT02845596 United States;
Melphalan
Case Comprehensive Cancer Center
1998 Phase 2 NCT00003336 United States;
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2009 - NCT00856388 United States;
1998 Phase 2/Phase 3 NCT00003816 United States;
Texas Oncology Cancer Center
2011 Phase 2 NCT01500161 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Melphalan Hydrochloride
Roswell Park Cancer Institute
2017 Phase 2 NCT03192397 United States;
Mesenchymal stem cells
CHU Sart-Tilman
2009 Phase 3 EUCTR2008-005594-35-BE Belgium;
Guangzhou General Hospital of Guangzhou Military Command
2013 Phase 2 NCT02247973 China;
Hebei Medical University
2017 Phase 1 NCT03055078 China;
Mesna
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2014 Phase 2 NCT02224872 United States;
St. Jude Children's Research Hospital
2021 Phase 2 NCT04558736 United States;
University of Rochester
2015 Phase 1 NCT03016806 United States;
Metformin
Department of Hematology, Second Medical Center, Chinese PLA General Hospital
2020 Phase 2 ChiCTR2000028833 China;
Methotrexate
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
Beth Israel Deaconess Medical Center
1999 Phase 2 NCT00636909 -
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
Michael Pulsipher, MD
2016 - NCT02845596 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Xiangya Hosptial of Central South University
2017 - ChiCTR-ONC-17012896 China;
Methylprednisolone
BioLineRx, Ltd.
2015 Phase 2 NCT02462252 United States;
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
1998 Phase 2 NCT00003336 United States;
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
M.D. Anderson Cancer Center
2012 Phase 2 NCT01624805 United States;
2005 Phase 2 NCT00806598 United States;
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
National Center for Research Resources (NCRR)
1995 Phase 2 NCT00004323 United States;
Northwestern Memorial Hospital
2001 - NCT00017654 United States;
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
Methylprednisolone (MP)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Miltenyi CD34 Reagent System
National Heart, Lung, and Blood Institute (NHLBI)
2010 Phase 2 NCT01174108 United States;
Muromonab-CD3
H. Lee Moffitt Cancer Center and Research Institute
1996 Phase 2 NCT00005852 -
Mycophenolate Mofetil (MMF)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2010 Phase 2 NCT01350245 United States;
Mycophenolate mofetil
Boston Children's Hospital
2012 Phase 2 NCT01659606 Norway;Sweden;United States;
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00005935 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2002 Phase 2 NCT00053989 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2011 Phase 2 NCT01384513 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Mycophenolate mofetil (MMF)
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Mycophenolic acid
Kobe University Graduate School of Medicine
2010 - JPRN-UMIN000004264 Japan;
Mycophenolic acid mofetil
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2014 Phase 2 NCT02224872 United States;
Nandrolone
National Heart, Lung, and Blood Institute (NHLBI)
1982 Phase 3 NCT00000597 -
Neoral
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
Non ATG Conditioning regimen
Assiut University
2019 Phase 2/Phase 3 NCT03295058 -
Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
Nonmyeloablative allogeneic hematopoietic stem cell transplantation
University of California, San Francisco
2005 - NCT00295997 United States;
Normal saline
Alberta Children's Hospital
2011 Phase 3 NCT01343680 Canada;
Noxafil Gastro resistant tablets
King's College Hospital NHS Foundation Trust
2016 Phase 4 EUCTR2016-001223-31-GB United Kingdom;
Noxafil®
King's College Hospital NHS Foundation Trust
2016 Phase 4 EUCTR2016-001223-31-GB United Kingdom;
Obatoclax mesylate (GX15-070MS)
Gemin X
2005 Phase 1 NCT00438178 Canada;United States;
PF-06462700
Pfizer
2020 Phase 3 NCT04350606 Japan;
Pegfilgrastim
M.D. Anderson Cancer Center
2012 Phase 2 NCT01624805 United States;
Peripheral Blood Stem Cell Transplantation
M.D. Anderson Cancer Center
2019 Phase 1/Phase 2 NCT03622788 United States;
2017 Phase 1 NCT02960646 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03333486 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
Peripheral blood stem cell transplantation
Case Comprehensive Cancer Center
2000 Phase 2 NCT00006379 United States;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Peripheral blood stem cell transplantation (PBSCT)
Sidney Kimmel Cancer Center at Thomas Jefferson University
2011 Phase 2 NCT01384513 United States;
Posaconazole
King's College Hospital NHS Trust
2016 Phase 4 NCT02875743 United Kingdom;
Seoul National University Hospital
2018 Phase 2 NCT03318159 Korea, Republic of;
Prednisolone
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
Prograf
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
R-ATG
National Heart, Lung, and Blood Institute (NHLBI)
2003 Phase 2 NCT00065260 United States;
RABBIT HUMAN T LYMPHOCYTE IMMUNOGLOBULIN
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
RATG
Ishiyama Ken
2019 Phase 2 JPRN-jRCTs071190032 Japan;
REGN7257
Regeneron Pharmaceuticals
2021 Phase 1/Phase 2 NCT04409080 France;Korea, Republic of;United Kingdom;United States;
Regeneron Pharmaceuticals, Inc.
2020 Phase 1;Phase 2 EUCTR2020-002031-29-GB France;Korea, Republic of;United Kingdom;United States;
2020 Phase 1;Phase 2 EUCTR2020-002031-29-FR France;Korea, Republic of;United Kingdom;United States;
REVOLADE - 25 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER(PA/ALU/PVC/ALU) 28 COMPRESSE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
REVOLADE - 50 MG - COMPRESSA RIVESTITA CON FILM - USO ORALE - BLISTER(PA/ALU/PVC/ALU
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
RNA analysis
City of Hope Medical Center
2010 - NCT01199562 United States;
RVG 101614
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
RVG 105155
VU University Medical Center
2015 Phase 4 EUCTR2014-001546-25-NL Netherlands;
Rabbit ATG
Northside Hospital, Inc.
2016 Phase 2 NCT02828592 United States;
Novartis Pharmaceuticals
2015 Phase 2 NCT02404025 Japan;
Rabbit ATG, (Genzyme)
Jinan Military General Hospital
2017 Phase 4 NCT02838992 China;
Rabbit ATG, Cyclosporine, Levamisole
Yizhou Zheng
2014 Phase 2 NCT02203396 China;
Rabbit ATG, Thymoglobuline (Genzyme)
King Faisal Specialist Hospital & Research Center
2008 Phase 2 NCT01530555 -
Rabbit anti-thymocyte globulin (ATG)
Michael Pulsipher, MD
2016 - NCT02845596 United States;
Rabbit anti-thymocyte globulin (r-ATG)
Novartis Pharmaceuticals
2020 Phase 2 NCT04328727 China;Japan;Korea, Republic of;Taiwan;
Rabbit antithymocyte globulin
European Group for Blood and Marrow Transplantation
2008 Phase 2 NCT00471848 France;Germany;Italy;Saudi Arabia;Switzerland;United Kingdom;
Rabbit antithymoglobulin (ATG)
Navy General Hospital, Beijing
2015 Phase 1/Phase 2 NCT02407470 China;
Rapamune
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Rapamycin
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Recombinant Methionyl Human Stem Cell Factor (r-metHuSCF)
National Heart, Lung, and Blood Institute (NHLBI)
1993 Phase 1 NCT00001398 United States;
Revolade
European Society for Blood and Marrow Transplantation
2015 - EUCTR2014-000363-40-ES Spain;
Universitätsklinikum Ulm
2015 Phase 2;Phase 3 EUCTR2014-000174-19-DE France;Germany;Italy;Netherlands;Switzerland;
RhTPO
Institute of Hematology, People's Hospital, Peking University
2019 - ChiCTR1800019669 China;
Tianjin Medical University General Hospital
2016 Phase 2 NCT02857530 China;
Rimiducid
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
Rituxan
Memorial Sloan Kettering Cancer Center
2018 Phase 1 NCT03531736 United States;
Rituximab
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2005 Phase 2 NCT00229619 United States;
Rivogenlecleucel
Bellicum Pharmaceuticals, Inc.
- Phase 2 EUCTR2014-000584-41-GB Italy;Spain;United Kingdom;
Rivogenleucleucel
Bellicum Pharmaceuticals, Inc.
2017 Phase 2 EUCTR2014-000584-41-ES Italy;Spain;United Kingdom;
Romiplostim
Anjali Sharathkumar
2020 Early Phase 1 NCT04478227 United States;
Kyowa Hakko Kirin Co., Ltd.
2016 Phase 2-3 JPRN-JapicCTI-163243 -
Kyowa Kirin Co., Ltd
2019 Phase 2-3 JPRN-JapicCTI-194962 Japan, Asia except Japan;
2019 Phase 2-3 JPRN-JapicCTI-194746 Japan, Asia except Japan;
Kyowa Kirin Co., Ltd.
2019 Phase 2/Phase 3 NCT04095936 Japan;
2019 Phase 2/Phase 3 NCT03957694 Japan;
2016 Phase 2/Phase 3 NCT02773290 Japan;Korea, Republic of;
SA
The First affiliated Hospital of Zhejiang Chinese Medical University
2017 - ChiCTR-IOR-17011653 China;
SANDIMMUN NEORAL - 10 MG CAPSULE MOLLI 50 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SANDIMMUN NEORAL - 100 MG CAPSULE MOLLI 30 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SANDIMMUN NEORAL - 25 MG CAPSULE MOLLI 50 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SANDIMMUN NEORAL - 50 MG CAPSULE MOLLI 50 CAPSULE
NOVARTIS PHARMA AG
2019 Phase 2 EUCTR2016-002814-29-IT Brazil;Hong Kong;Hungary;India;Italy;Korea, Democratic People's Republic of;Mexico;Netherlands;Spain;Thailand;Turkey;
SB497115
Universitätsklinikum Ulm
2015 Phase 2;Phase 3 EUCTR2014-000174-19-DE France;Germany;Italy;Netherlands;Switzerland;
SODIUM CHLORIDE SOLUTION
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
SULFAMETH
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
Sandimmun Neoral
Karolinska Institutet
2007 - EUCTR2006-006577-25-SE Finland;Sweden;
Sargramostim
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
2002 - NCT00053157 United States;
Sirolimus
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
National Heart, Lung, and Blood Institute (NHLBI)
2016 Phase 2 NCT02979873 United States;
Office of Rare Diseases (ORD)
2006 Phase 1/Phase 2 NCT00319878 United States;
Roswell Park Cancer Institute
2017 Phase 2 NCT03192397 United States;
Sodium chloride
EBMT (European group for Blood and Marrow Transplantation)
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
Standard Vitamin D3 Supplementation
Phoenix Children's Hospital
2017 Phase 4 NCT03176849 United States;
Standard therapy of septic shock
National Research Center for Hematology, Russia
2012 Phase 1/Phase 2 NCT01849237 Russian Federation;
Stanozolol
The First Affiliated Hospital of Zhengzhou University
2016 - ChiCTR-IOR-16008738 China;
Stem Cell Transplant
Masonic Cancer Center, University of Minnesota
2015 - NCT02162420 United States;
Stem Cell Transplantation
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Stem cell infusion
Baylor College of Medicine
2002 Phase 2 NCT00578903 United States;
2001 Phase 1/Phase 2 NCT00590460 United States;
T Cell-Depleted Donor Lymphocyte Infusion
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
TRIMETHOPRIM SULFATE
José Miguel Cisneros Herreros
2012 Phase 3 EUCTR2011-005152-34-ES Spain;
Tacrolimus
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00358657 United States;
M.D. Anderson Cancer Center
2017 Phase 1 NCT02960646 United States;
Medical College of Wisconsin
2017 Phase 2 NCT02918292 United States;
Peking Union Medical College Hospital
2020 Phase 2 NCT04403321 China;
Roswell Park Cancer Institute
2012 Phase 2 NCT01529827 United States;
2002 Phase 2 NCT00053989 United States;
Sidney Kimmel Cancer Center at Thomas Jefferson University
2015 Phase 2 NCT02566304 United States;
2011 Phase 2 NCT01384513 United States;
2010 Phase 2 NCT01350245 United States;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
Thomas Jefferson University
2021 Phase 2 NCT05031897 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Testosterone undecanoate
Jinhua people's Hospital
2015 Phase 2-3 ChiCTR1900028153 -
Therapeutic allogeneic lymphocytes
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
University of California, San Francisco
2005 - NCT00295997 United States;
Thiotepa
Memorial Sloan Kettering Cancer Center
1995 Phase 2 NCT00002718 United States;
Roswell Park Cancer Institute
1998 Phase 2/Phase 3 NCT00003816 United States;
Thymoglobulin
Kanto Study Group for Cell Therapy
2011 Phase 2 JPRN-UMIN000006071 Japan;
King's College Hospital NHS Foundation Trust
2008 Phase 2 EUCTR2007-001657-26-GB United Kingdom;
M.D. Anderson Cancer Center
2005 Phase 2 NCT00806598 United States;
Nagoya University
2012 Phase 3 NCT01844635 Japan;
2012 - JPRN-UMIN000011134 Japan,Asia(except Japan);
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
2016 Phase 4 NCT02745717 China;
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
2016 Phase 2 NCT02833805 United States;
2014 Phase 2 NCT02224872 United States;
Thymoglobuline®/Thymoglobulin®
EBMT (European Group for Blood and Marrow Transplantation)
2009 - EUCTR2007-000902-55-DE France;Germany;United Kingdom;
EBMT (European group for Blood and Marrow Transplantation)
2008 - EUCTR2007-000902-55-FR France;Germany;United Kingdom;
2007 Phase 2 EUCTR2007-000902-55-GB France;Germany;United Kingdom;
Total Body Irradiation
Masonic Cancer Center, University of Minnesota
2007 Phase 2/Phase 3 NCT00455312 United States;
Total Body Irradiation (TBI) (Plan 1)
Masonic Cancer Center, University of Minnesota
2018 Phase 2 NCT03579875 United States;
Umbilical Cord Blood
National Heart, Lung, and Blood Institute (NHLBI)
2008 Phase 2 NCT00604201 United States;
Umbilical Cord Blood After Myeloablative Conditioning
Tufts Medical Center
2005 Phase 2 NCT00676806 United States;
Umbilical Cord Blood After Reduced-Intensity Conditioning
Tufts Medical Center
2005 Phase 2 NCT00676806 United States;
Umbilical Cord Blood Transplantation
New York Blood Center
1993 Early Phase 1 NCT00212407 United States;
Umbilical cord blood transplantation
Case Comprehensive Cancer Center
2002 Phase 1 NCT00054236 United States;
1998 Phase 2 NCT00003336 United States;
Fred Hutchinson Cancer Research Center
2006 Phase 1 NCT00354419 United States;
Roswell Park Cancer Institute
2002 Phase 2 NCT00053989 United States;
Valganciclovir
City of Hope Medical Center
2010 - NCT01199562 United States;
Voriconazole
Institute of Hematology & Blood Diseases Hospital, CAMS & PUMC
2013 - ChiCTR-PRC-13003130 China;
polymerase chain reaction
City of Hope Medical Center
2010 - NCT01199562 United States;
polymorphism analysis
Fred Hutchinson Cancer Research Center
2006 Phase 2 NCT00343785 Canada;United States;
protein expression analysis
City of Hope Medical Center
2010 - NCT01199562 United States;