17. Multiple system atrophy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 119 / Drugs : 138 - (DrugBank : 44) / Drug target genes : 59 - Drug target pathways : 111
Drugs and their primary sponsors and trial info
1) Inosine 5'-monophosphate
Yonsei University
2018 Phase 2 NCT03403309 Korea, Republic of;
AAV2-GDNF gene therapy
Brain Neurotherapy Bio, Inc.
2022 Phase 1 NCT04680065 United States;
AFFITOPE® PD01A + Adjuvant
Affiris AG
2014 Phase 1 NCT02270489 France;
AFFITOPE® PD03A + Adjuvant
Affiris AG
2014 Phase 1 NCT02270489 France;
ATH434 dose level 1
Alterity Therapeutics
2022 Phase 2 NCT05109091 -
ATH434 dose level 2
Alterity Therapeutics
2022 Phase 2 NCT05109091 -
AZD3241
AstraZeneca
2015 Phase 2 NCT02388295 Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
AstraZeneca AB
2015 Phase 2 EUCTR2014-004902-13-SE Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-GB Finland;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-FI Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
2010 - EUCTR2009-018157-23-GB Austria;Spain;United Kingdom;
2010 - EUCTR2009-018157-23-ES Austria;Spain;United Kingdom;
2010 - EUCTR2009-018157-23-AT Austria;Spain;United Kingdom;
AZILECT 1 mg comprimidos
Teva Pharmaceutical Industries Ltd
2009 Phase 2 EUCTR2009-014644-11-ES Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Abdominal compression
Vanderbilt University Medical Center
2020 Early Phase 1 NCT04620382 United States;
Accelerometer
Vanderbilt University Medical Center
2021 - NCT04782830 United States;
Adjuvant without active component
Affiris AG
2014 Phase 1 NCT02270489 France;
Allogeneic Umbilical Cord Mesenchymal Stem Cell Implantation
Indonesia University
2020 - NCT04876326 Indonesia;
Allogeneic Umbilical Cord Mesenchymal Stem Cell and Adipose Secretome Implantation
Indonesia University
2020 - NCT04876326 Indonesia;
Ampreloxetine
THERAVANCE BIOPHARMA ANTIBIOTICS, INC.
2019 Phase 3 EUCTR2018-003289-15-IT Austria;Bulgaria;Canada;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Theravance Biopharma Ireland Limited
2020 Phase 3 EUCTR2018-003289-15-DE Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-HU Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-ES Austria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Ampreloxetine chydrochloride
Theravance Biopharma Ireland Limited
2019 Phase 3 EUCTR2018-003289-15-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Ampreloxetine hydrochloride
Theravance Biopharma Ireland Limited
2020 Phase 3 EUCTR2018-003941-41-PT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003941-41-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003289-15-PT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-IT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-HU Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-ES Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-EE Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-EE Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-DK Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Angiotensin-(1-7)
Vanderbilt University Medical Center
2016 Early Phase 1 NCT02591173 United States;
Anti-Parkinson medication
Beth Israel Deaconess Medical Center
2016 - NCT02994719 United States;
Atomexetine
NYU Langone Health
2016 Phase 2 NCT02796209 United States;
Autologous Adipose Mesenchymal Stem Cell Implantation
Indonesia University
2020 - NCT04876326 Indonesia;
Autologous Mesenchymal Stem Cells
Mayo Clinic
2021 Phase 2 NCT05167721 United States;
2012 Phase 1/Phase 2 NCT02315027 United States;
Autologous mesenchymal stem cells
Yonsei University
2008 Phase 2 NCT00911365 Korea, Republic of;
Automated abdominal binder
Vanderbilt University Medical Center
2018 Phase 1/Phase 2 NCT03482297 United States;
BHV-3241
Biohaven Pharmaceuticals, Inc
2020 Phase 3 EUCTR2019-001100-38-DE Austria;China;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-GB Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-FR Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-AT Austria;China;France;Germany;Italy;United Kingdom;United States;
Biohaven Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2019-001100-38-IT Austria;China;France;Germany;Italy;United Kingdom;United States;
BHV-4157
University of California, Los Angeles
2017 Phase 3 NCT03408080 United States;
BIIB101
Biogen
2020 Phase 1 NCT04165486 Austria;France;Germany;Portugal;United Kingdom;
Blood sampling
University Hospital, Bordeaux
2020 - NCT04250493 France;
Brain Magnetic Resonance Imaging (MRI)
University Hospital, Bordeaux
2020 - NCT04250493 France;
Bydureon
University College London (UCL)
2020 Phase 2 EUCTR2020-000122-26-GB United Kingdom;
CS10BR05
Corestem, Inc.
2018 Phase 1 NCT03265444 Korea, Republic of;
Captopril
Vanderbilt University
2011 Phase 1 NCT01292694 United States;
Carbidopa
National Institute of Neurological Disorders and Stroke (NINDS)
2007 Phase 1/Phase 2 NCT00547911 United States;
Carbidopa 200mg oral dose
Daniel Claassen
2020 Phase 1 NCT04246437 United States;
DaTSCAN™ Ioflupane (123I) Injection
GE Healthcare
2020 Phase 3 NCT04193527 China;
Deep Brain Stimulation
Beth Israel Deaconess Medical Center
2016 - NCT02994719 United States;
Determination of objective and subjective pain threshold
University Hospital, Toulouse
2011 - NCT01577992 France;
Domperidone
Royal Brisbane and Women's Hospital
2005 Phase 1 NCT00103597 Australia;
Droxidopa
Chelsea Therapeutics
2008 Phase 3 NCT00738062 Australia;Canada;New Zealand;United States;
Loma Linda University
2021 Phase 2 NCT03446807 United States;
Mount Sinai School of Medicine
1999 - NCT00004478 United States;
National Institute of Neurological Disorders and Stroke (NINDS)
2007 Phase 1/Phase 2 NCT00547911 United States;
Vanderbilt University Medical Center
2016 Phase 1 NCT02897063 United States;
EGCG as putative neuroprotective agent
Dr. Johannes Levin
2014 Phase 3 NCT02008721 Germany;
Emeramide
NBMI Science Ltd.
2019 Phase 2 EUCTR2018-000506-34-SI Slovenia;
Entacapone
National Institute of Neurological Disorders and Stroke (NINDS)
2007 Phase 1/Phase 2 NCT00547911 United States;
Entacapone 400mg oral dose
Daniel Claassen
2020 Phase 1 NCT04246437 United States;
Exenatide
University College London (UCL)
2020 Phase 2 EUCTR2020-000122-26-GB United Kingdom;
Exenatide Pen Injector [Bydureon]
University College, London
2020 Phase 2 NCT04431713 United Kingdom;
Fipamezole
Juvantia Pharma Ltd
2008 Phase 2 NCT00758849 France;Portugal;
Fipamezole hydrochloride 30 mg oral disintegrating tablets
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
Fipamezole hydrochloride 60 mg oral disintegrating tablets
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
Fipamezole hydrochloride 90 mg oral disintegrating tablets
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
Fludrocortisone
Royal Brisbane and Women's Hospital
2005 Phase 1 NCT00103597 Australia;
Flumazenil
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
2013 - JPRN-UMIN000011111 Japan;
Fluoxétine
University Hospital, Bordeaux
2010 - NCT01136213 France;
Flutemetamol F18
Skane University Hospital
2017 - NCT03174938 Sweden;
Gold
Navy general hospital
2015 Phase 0 ChiCTR-DPC-15005941 China;
West China Hospital of Sichuan University
2020 Phase 0 ChiCTR2000033282 China;
Homeostasis Model Assessment of insulin resistance (HOMA)
University Hospital, Bordeaux
2020 - NCT04250493 France;
Hydrogen
Juntendo University School of Medicine, Department of Neurology
2012 Phase 1 JPRN-UMIN000008959 Japan;
IUPAC name: 1-(2-Isopropoxyethyl)-2-thioxo-1,2,3,5-tetrahydro-pyrrolo[3,2-d] pyrimidin-4-one
AstraZeneca AB
2015 Phase 2 EUCTR2014-004902-13-SE Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-GB Finland;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-FI Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
Intranasal Insulin
Peter Novak
2014 Phase 2 NCT02064166 United States;
Intravenous immunoglobulin (IVIg)
University of Massachusetts, Worcester
2008 Phase 2 NCT00750867 United States;
Intravesical injection of Botulinum A toxin
University Of Perugia
2008 Phase 4 NCT00822913 -
JP-1730/F01
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
JP-1730/F02
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
JP-1730/F03
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
L-Threo DOPS
University Hospital, Toulouse
2014 Phase 2/Phase 3 NCT02071459 France;
LITIO CARBONATO
UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
2009 - EUCTR2009-016377-15-IT Italy;
Levodopa
University Hospital, Toulouse
2002 - NCT01044992 France;
Levodopa test
University Hospital, Toulouse
2011 - NCT01577992 France;
Losartan
Vanderbilt University
2011 Phase 1 NCT01292694 United States;
Lu AF82422
H. Lundbeck A/S
2021 Phase 2 NCT05104476 Japan;United States;
Metoprolol tartrate
Vanderbilt University
2010 - NCT01044693 United States;
Midodrine
Vanderbilt University Medical Center
2020 Early Phase 1 NCT04620382 United States;
2018 Phase 1/Phase 2 NCT03482297 United States;
2016 Phase 1 NCT02897063 United States;
2015 Phase 1 NCT02429557 United States;
Midodrine or atomoxetine pill
Vanderbilt University Medical Center
2021 - NCT04782830 United States;
Modal
Oregon Health and Science University
2021 - NCT04468919 United States;
N1,N3-BIS(2-MERCAPTOETHYL) ISOPHTHALAMIDE
NBMI Science Ltd.
2019 Phase 2 EUCTR2018-000506-34-SI Slovenia;
NBMI
EmeraMed
2019 Phase 2 NCT04184063 Slovenia;
NBMI Science Ltd.
2019 Phase 2 EUCTR2018-000506-34-SI Slovenia;
NT 101
Merz Pharmaceuticals GmbH
2014 Phase 3 EUCTR2012-005539-10-DE Germany;Poland;United States;
Nebivolol
Vanderbilt University
2010 - NCT01044693 United States;
Nitrogen
Juntendo University School of Medicine, Department of Neurology
2012 Phase 1 JPRN-UMIN000008959 Japan;
Normal saline
Yonsei University
2008 Phase 2 NCT00911365 Korea, Republic of;
PROZAC
CHU Toulouse
2008 - EUCTR2007-004922-26-FR France;
Pseudoephedrine
Vanderbilt University
2003 Phase 1 NCT00179023 United States;
Pseudoephedrine + 480 ml water
Vanderbilt University
2014 Early Phase 1 NCT02149901 United States;
Pseudoephedrine + 50 ml water
Vanderbilt University
2014 Early Phase 1 NCT02149901 United States;
RASAGILINA MESILATO
Teva Pharmaceutical Industries Ltd
2009 Phase 2 EUCTR2009-014644-11-ES Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Raclopride
Nagoya City Rehabilitation Agency
2019 - JPRN-UMIN000036952 Japan;
Rasagiline
Teva Pharmaceutical Industries Ltd
2009 - EUCTR2009-014644-11-IT Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Rasagiline mesylate
Teva Pharmaceutical Industries
2009 Phase 2 NCT00977665 Austria;Canada;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Spain;United Kingdom;United States;
Teva Pharmaceutical Industries Ltd
2010 Phase 2 EUCTR2009-014644-11-GB Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2010 - EUCTR2009-014644-11-PT Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2010 - EUCTR2009-014644-11-NL Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2010 - EUCTR2009-014644-11-AT Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2009 Phase 2 EUCTR2009-014644-11-FR Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2009 - EUCTR2009-014644-11-HU Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2009 - EUCTR2009-014644-11-DE Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Rifampicin
Phillip Low
2011 Phase 3 NCT01287221 United States;
Riluzole
King's College London
2000 Phase 3 NCT00211224 United Kingdom;
Rituximab
First Affiliated Hospital of Fujian Medical University
2019 Phase 2 NCT04004819 China;
SAFINAMIDE METANSOLFONATO
ZAMBON SPA
2019 Phase 2 EUCTR2018-004145-16-IT Italy;Spain;
Safinamide Methanesulfonate
Zambon SpA
2019 Phase 2 NCT03753763 Italy;Spain;
Safinamide methanesulfonate
Zambon SpA
2019 Phase 2 EUCTR2018-004145-16-ES Spain;
Saline
Vanderbilt University
2010 Phase 1 NCT01119417 United States;
Vanderbilt University Medical Center
2016 Early Phase 1 NCT02591173 United States;
Sham binder
Vanderbilt University Medical Center
2018 Phase 1/Phase 2 NCT03482297 United States;
Sham compression
Vanderbilt University Medical Center
2020 Early Phase 1 NCT04620382 United States;
Sildenafil
Vanderbilt University
2010 - NCT01044693 United States;
Sirolimus
NYU Langone Health
2018 Phase 2 NCT03589976 United States;
Sunphenon EGCg
Hospital of the Ludwig-Maximilians-University of Munich
2013 Phase 3 EUCTR2012-000928-18-DE Germany;
TD-9855
THERAVANCE BIOPHARMA ANTIBIOTICS, INC.
2019 Phase 3 EUCTR2018-003289-15-IT Austria;Bulgaria;Canada;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Theravance Biopharma
2016 Phase 2 NCT02705755 United States;
Theravance Biopharma Ireland Limited
2020 Phase 3 EUCTR2018-003941-41-PT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003941-41-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003289-15-PT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003289-15-DE Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-IT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-HU Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-ES Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-EE Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-HU Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-ES Austria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-EE Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-DK Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Tllsh2910
National Taiwan University Hospital
2019 Phase 3 NCT03901638 Taiwan;
Tolterodine
Xuanwu Hospital, Capital Medical University
2021 - ChiCTR2100046394 China;
Trimethaphan
Vanderbilt University
2016 Phase 1 NCT02726711 United States;
2003 Phase 1 NCT00179023 United States;
Ubiquinol
Department of Neurology, the University of Tokyo Hospital
2013 - JPRN-UMIN000010712 Japan;
Verdiperstat
Biohaven Pharmaceuticals, Inc
2020 Phase 3 EUCTR2019-001100-38-DE Austria;China;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-GB Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-FR Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-AT Austria;China;France;Germany;Italy;United Kingdom;United States;
Biohaven Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2019-001100-38-IT Austria;China;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 NCT03952806 Austria;France;Germany;Italy;United Kingdom;United States;
Brigham and Women's Hospital
2020 Early Phase 1 NCT04616456 United States;
Water
Juntendo University School of Medicine, Department of Neurology
2012 Phase 1 JPRN-UMIN000008959 Japan;
Xadago
ZAMBON SPA
2019 Phase 2 EUCTR2018-004145-16-IT Italy;Spain;
Zambon SpA
2019 Phase 2 EUCTR2018-004145-16-ES Spain;
Xeomin
Merz Pharmaceuticals GmbH
2014 Phase 3 EUCTR2012-005539-10-DE Germany;Poland;United States;
Z7219
ZAMBON SPA
2019 Phase 2 EUCTR2018-004145-16-IT Italy;Spain;
Zoledronic Acid 5Mg/Bag 100Ml Inj
California Pacific Medical Center Research Institute
2019 Phase 4 NCT03924414 United States;
[18F]FDOPA
Daniel Claassen
2020 Phase 1 NCT04246437 United States;
[F-18]PBR06
Brigham and Women's Hospital
2020 Early Phase 1 NCT04616456 United States;
Yonsei University
2018 Phase 2 NCT03403309 Korea, Republic of;
AAV2-GDNF gene therapy
Brain Neurotherapy Bio, Inc.
2022 Phase 1 NCT04680065 United States;
AFFITOPE® PD01A + Adjuvant
Affiris AG
2014 Phase 1 NCT02270489 France;
AFFITOPE® PD03A + Adjuvant
Affiris AG
2014 Phase 1 NCT02270489 France;
ATH434 dose level 1
Alterity Therapeutics
2022 Phase 2 NCT05109091 -
ATH434 dose level 2
Alterity Therapeutics
2022 Phase 2 NCT05109091 -
AZD3241
AstraZeneca
2015 Phase 2 NCT02388295 Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
AstraZeneca AB
2015 Phase 2 EUCTR2014-004902-13-SE Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-GB Finland;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-FI Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
2010 - EUCTR2009-018157-23-GB Austria;Spain;United Kingdom;
2010 - EUCTR2009-018157-23-ES Austria;Spain;United Kingdom;
2010 - EUCTR2009-018157-23-AT Austria;Spain;United Kingdom;
AZILECT 1 mg comprimidos
Teva Pharmaceutical Industries Ltd
2009 Phase 2 EUCTR2009-014644-11-ES Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Abdominal compression
Vanderbilt University Medical Center
2020 Early Phase 1 NCT04620382 United States;
Accelerometer
Vanderbilt University Medical Center
2021 - NCT04782830 United States;
Adjuvant without active component
Affiris AG
2014 Phase 1 NCT02270489 France;
Allogeneic Umbilical Cord Mesenchymal Stem Cell Implantation
Indonesia University
2020 - NCT04876326 Indonesia;
Allogeneic Umbilical Cord Mesenchymal Stem Cell and Adipose Secretome Implantation
Indonesia University
2020 - NCT04876326 Indonesia;
Ampreloxetine
THERAVANCE BIOPHARMA ANTIBIOTICS, INC.
2019 Phase 3 EUCTR2018-003289-15-IT Austria;Bulgaria;Canada;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Theravance Biopharma Ireland Limited
2020 Phase 3 EUCTR2018-003289-15-DE Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-HU Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-ES Austria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Ampreloxetine chydrochloride
Theravance Biopharma Ireland Limited
2019 Phase 3 EUCTR2018-003289-15-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Ampreloxetine hydrochloride
Theravance Biopharma Ireland Limited
2020 Phase 3 EUCTR2018-003941-41-PT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003941-41-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003289-15-PT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-IT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-HU Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-ES Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-EE Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-EE Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-DK Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Angiotensin-(1-7)
Vanderbilt University Medical Center
2016 Early Phase 1 NCT02591173 United States;
Anti-Parkinson medication
Beth Israel Deaconess Medical Center
2016 - NCT02994719 United States;
Atomexetine
NYU Langone Health
2016 Phase 2 NCT02796209 United States;
Autologous Adipose Mesenchymal Stem Cell Implantation
Indonesia University
2020 - NCT04876326 Indonesia;
Autologous Mesenchymal Stem Cells
Mayo Clinic
2021 Phase 2 NCT05167721 United States;
2012 Phase 1/Phase 2 NCT02315027 United States;
Autologous mesenchymal stem cells
Yonsei University
2008 Phase 2 NCT00911365 Korea, Republic of;
Automated abdominal binder
Vanderbilt University Medical Center
2018 Phase 1/Phase 2 NCT03482297 United States;
BHV-3241
Biohaven Pharmaceuticals, Inc
2020 Phase 3 EUCTR2019-001100-38-DE Austria;China;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-GB Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-FR Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-AT Austria;China;France;Germany;Italy;United Kingdom;United States;
Biohaven Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2019-001100-38-IT Austria;China;France;Germany;Italy;United Kingdom;United States;
BHV-4157
University of California, Los Angeles
2017 Phase 3 NCT03408080 United States;
BIIB101
Biogen
2020 Phase 1 NCT04165486 Austria;France;Germany;Portugal;United Kingdom;
Blood sampling
University Hospital, Bordeaux
2020 - NCT04250493 France;
Brain Magnetic Resonance Imaging (MRI)
University Hospital, Bordeaux
2020 - NCT04250493 France;
Bydureon
University College London (UCL)
2020 Phase 2 EUCTR2020-000122-26-GB United Kingdom;
CS10BR05
Corestem, Inc.
2018 Phase 1 NCT03265444 Korea, Republic of;
Captopril
Vanderbilt University
2011 Phase 1 NCT01292694 United States;
Carbidopa
National Institute of Neurological Disorders and Stroke (NINDS)
2007 Phase 1/Phase 2 NCT00547911 United States;
Carbidopa 200mg oral dose
Daniel Claassen
2020 Phase 1 NCT04246437 United States;
DaTSCAN™ Ioflupane (123I) Injection
GE Healthcare
2020 Phase 3 NCT04193527 China;
Deep Brain Stimulation
Beth Israel Deaconess Medical Center
2016 - NCT02994719 United States;
Determination of objective and subjective pain threshold
University Hospital, Toulouse
2011 - NCT01577992 France;
Domperidone
Royal Brisbane and Women's Hospital
2005 Phase 1 NCT00103597 Australia;
Droxidopa
Chelsea Therapeutics
2008 Phase 3 NCT00738062 Australia;Canada;New Zealand;United States;
Loma Linda University
2021 Phase 2 NCT03446807 United States;
Mount Sinai School of Medicine
1999 - NCT00004478 United States;
National Institute of Neurological Disorders and Stroke (NINDS)
2007 Phase 1/Phase 2 NCT00547911 United States;
Vanderbilt University Medical Center
2016 Phase 1 NCT02897063 United States;
EGCG as putative neuroprotective agent
Dr. Johannes Levin
2014 Phase 3 NCT02008721 Germany;
Emeramide
NBMI Science Ltd.
2019 Phase 2 EUCTR2018-000506-34-SI Slovenia;
Entacapone
National Institute of Neurological Disorders and Stroke (NINDS)
2007 Phase 1/Phase 2 NCT00547911 United States;
Entacapone 400mg oral dose
Daniel Claassen
2020 Phase 1 NCT04246437 United States;
Exenatide
University College London (UCL)
2020 Phase 2 EUCTR2020-000122-26-GB United Kingdom;
Exenatide Pen Injector [Bydureon]
University College, London
2020 Phase 2 NCT04431713 United Kingdom;
Fipamezole
Juvantia Pharma Ltd
2008 Phase 2 NCT00758849 France;Portugal;
Fipamezole hydrochloride 30 mg oral disintegrating tablets
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
Fipamezole hydrochloride 60 mg oral disintegrating tablets
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
Fipamezole hydrochloride 90 mg oral disintegrating tablets
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
Fludrocortisone
Royal Brisbane and Women's Hospital
2005 Phase 1 NCT00103597 Australia;
Flumazenil
Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
2013 - JPRN-UMIN000011111 Japan;
Fluoxétine
University Hospital, Bordeaux
2010 - NCT01136213 France;
Flutemetamol F18
Skane University Hospital
2017 - NCT03174938 Sweden;
Gold
Navy general hospital
2015 Phase 0 ChiCTR-DPC-15005941 China;
West China Hospital of Sichuan University
2020 Phase 0 ChiCTR2000033282 China;
Homeostasis Model Assessment of insulin resistance (HOMA)
University Hospital, Bordeaux
2020 - NCT04250493 France;
Hydrogen
Juntendo University School of Medicine, Department of Neurology
2012 Phase 1 JPRN-UMIN000008959 Japan;
IUPAC name: 1-(2-Isopropoxyethyl)-2-thioxo-1,2,3,5-tetrahydro-pyrrolo[3,2-d] pyrimidin-4-one
AstraZeneca AB
2015 Phase 2 EUCTR2014-004902-13-SE Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-GB Finland;Sweden;United Kingdom;United States;
2015 Phase 2 EUCTR2014-004902-13-FI Austria;Finland;France;Italy;Sweden;United Kingdom;United States;
Intranasal Insulin
Peter Novak
2014 Phase 2 NCT02064166 United States;
Intravenous immunoglobulin (IVIg)
University of Massachusetts, Worcester
2008 Phase 2 NCT00750867 United States;
Intravesical injection of Botulinum A toxin
University Of Perugia
2008 Phase 4 NCT00822913 -
JP-1730/F01
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
JP-1730/F02
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
JP-1730/F03
Juvantia Pharma Ltd
2008 - EUCTR2007-004890-24-PT France;Portugal;
2008 - EUCTR2007-004890-24-FR France;Portugal;
L-Threo DOPS
University Hospital, Toulouse
2014 Phase 2/Phase 3 NCT02071459 France;
LITIO CARBONATO
UNIVERSITA` DEGLI STUDI DI NAPOLI FEDERICO II
2009 - EUCTR2009-016377-15-IT Italy;
Levodopa
University Hospital, Toulouse
2002 - NCT01044992 France;
Levodopa test
University Hospital, Toulouse
2011 - NCT01577992 France;
Losartan
Vanderbilt University
2011 Phase 1 NCT01292694 United States;
Lu AF82422
H. Lundbeck A/S
2021 Phase 2 NCT05104476 Japan;United States;
Metoprolol tartrate
Vanderbilt University
2010 - NCT01044693 United States;
Midodrine
Vanderbilt University Medical Center
2020 Early Phase 1 NCT04620382 United States;
2018 Phase 1/Phase 2 NCT03482297 United States;
2016 Phase 1 NCT02897063 United States;
2015 Phase 1 NCT02429557 United States;
Midodrine or atomoxetine pill
Vanderbilt University Medical Center
2021 - NCT04782830 United States;
Modal
Oregon Health and Science University
2021 - NCT04468919 United States;
N1,N3-BIS(2-MERCAPTOETHYL) ISOPHTHALAMIDE
NBMI Science Ltd.
2019 Phase 2 EUCTR2018-000506-34-SI Slovenia;
NBMI
EmeraMed
2019 Phase 2 NCT04184063 Slovenia;
NBMI Science Ltd.
2019 Phase 2 EUCTR2018-000506-34-SI Slovenia;
NT 101
Merz Pharmaceuticals GmbH
2014 Phase 3 EUCTR2012-005539-10-DE Germany;Poland;United States;
Nebivolol
Vanderbilt University
2010 - NCT01044693 United States;
Nitrogen
Juntendo University School of Medicine, Department of Neurology
2012 Phase 1 JPRN-UMIN000008959 Japan;
Normal saline
Yonsei University
2008 Phase 2 NCT00911365 Korea, Republic of;
PROZAC
CHU Toulouse
2008 - EUCTR2007-004922-26-FR France;
Pseudoephedrine
Vanderbilt University
2003 Phase 1 NCT00179023 United States;
Pseudoephedrine + 480 ml water
Vanderbilt University
2014 Early Phase 1 NCT02149901 United States;
Pseudoephedrine + 50 ml water
Vanderbilt University
2014 Early Phase 1 NCT02149901 United States;
RASAGILINA MESILATO
Teva Pharmaceutical Industries Ltd
2009 Phase 2 EUCTR2009-014644-11-ES Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Raclopride
Nagoya City Rehabilitation Agency
2019 - JPRN-UMIN000036952 Japan;
Rasagiline
Teva Pharmaceutical Industries Ltd
2009 - EUCTR2009-014644-11-IT Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Rasagiline mesylate
Teva Pharmaceutical Industries
2009 Phase 2 NCT00977665 Austria;Canada;France;Germany;Hungary;Israel;Italy;Netherlands;Portugal;Spain;United Kingdom;United States;
Teva Pharmaceutical Industries Ltd
2010 Phase 2 EUCTR2009-014644-11-GB Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2010 - EUCTR2009-014644-11-PT Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2010 - EUCTR2009-014644-11-NL Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2010 - EUCTR2009-014644-11-AT Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2009 Phase 2 EUCTR2009-014644-11-FR Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2009 - EUCTR2009-014644-11-HU Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
2009 - EUCTR2009-014644-11-DE Austria;France;Germany;Hungary;Italy;Netherlands;Portugal;Spain;United Kingdom;
Rifampicin
Phillip Low
2011 Phase 3 NCT01287221 United States;
Riluzole
King's College London
2000 Phase 3 NCT00211224 United Kingdom;
Rituximab
First Affiliated Hospital of Fujian Medical University
2019 Phase 2 NCT04004819 China;
SAFINAMIDE METANSOLFONATO
ZAMBON SPA
2019 Phase 2 EUCTR2018-004145-16-IT Italy;Spain;
Safinamide Methanesulfonate
Zambon SpA
2019 Phase 2 NCT03753763 Italy;Spain;
Safinamide methanesulfonate
Zambon SpA
2019 Phase 2 EUCTR2018-004145-16-ES Spain;
Saline
Vanderbilt University
2010 Phase 1 NCT01119417 United States;
Vanderbilt University Medical Center
2016 Early Phase 1 NCT02591173 United States;
Sham binder
Vanderbilt University Medical Center
2018 Phase 1/Phase 2 NCT03482297 United States;
Sham compression
Vanderbilt University Medical Center
2020 Early Phase 1 NCT04620382 United States;
Sildenafil
Vanderbilt University
2010 - NCT01044693 United States;
Sirolimus
NYU Langone Health
2018 Phase 2 NCT03589976 United States;
Sunphenon EGCg
Hospital of the Ludwig-Maximilians-University of Munich
2013 Phase 3 EUCTR2012-000928-18-DE Germany;
TD-9855
THERAVANCE BIOPHARMA ANTIBIOTICS, INC.
2019 Phase 3 EUCTR2018-003289-15-IT Austria;Bulgaria;Canada;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Theravance Biopharma
2016 Phase 2 NCT02705755 United States;
Theravance Biopharma Ireland Limited
2020 Phase 3 EUCTR2018-003941-41-PT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003941-41-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003289-15-PT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2020 Phase 3 EUCTR2018-003289-15-DE Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-IT Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-HU Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-ES Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-EE Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003941-41-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-PL Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-HU Austria;Bulgaria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-GB Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-ES Austria;Canada;Czech Republic;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-EE Australia;Austria;Bulgaria;Canada;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;New Zealand;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-DK Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-BG Argentina;Australia;Austria;Bulgaria;Canada;Chile;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
2019 Phase 3 EUCTR2018-003289-15-AT Argentina;Australia;Austria;Bulgaria;Canada;Chile;Czechia;Denmark;Estonia;France;Germany;Hungary;Israel;Italy;Mexico;New Zealand;Peru;Poland;Portugal;Russian Federation;Spain;Ukraine;United Kingdom;United States;
Tllsh2910
National Taiwan University Hospital
2019 Phase 3 NCT03901638 Taiwan;
Tolterodine
Xuanwu Hospital, Capital Medical University
2021 - ChiCTR2100046394 China;
Trimethaphan
Vanderbilt University
2016 Phase 1 NCT02726711 United States;
2003 Phase 1 NCT00179023 United States;
Ubiquinol
Department of Neurology, the University of Tokyo Hospital
2013 - JPRN-UMIN000010712 Japan;
Verdiperstat
Biohaven Pharmaceuticals, Inc
2020 Phase 3 EUCTR2019-001100-38-DE Austria;China;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-GB Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-FR Austria;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 EUCTR2019-001100-38-AT Austria;China;France;Germany;Italy;United Kingdom;United States;
Biohaven Pharmaceuticals, Inc.
2020 Phase 3 EUCTR2019-001100-38-IT Austria;China;France;Germany;Italy;United Kingdom;United States;
2019 Phase 3 NCT03952806 Austria;France;Germany;Italy;United Kingdom;United States;
Brigham and Women's Hospital
2020 Early Phase 1 NCT04616456 United States;
Water
Juntendo University School of Medicine, Department of Neurology
2012 Phase 1 JPRN-UMIN000008959 Japan;
Xadago
ZAMBON SPA
2019 Phase 2 EUCTR2018-004145-16-IT Italy;Spain;
Zambon SpA
2019 Phase 2 EUCTR2018-004145-16-ES Spain;
Xeomin
Merz Pharmaceuticals GmbH
2014 Phase 3 EUCTR2012-005539-10-DE Germany;Poland;United States;
Z7219
ZAMBON SPA
2019 Phase 2 EUCTR2018-004145-16-IT Italy;Spain;
Zoledronic Acid 5Mg/Bag 100Ml Inj
California Pacific Medical Center Research Institute
2019 Phase 4 NCT03924414 United States;
[18F]FDOPA
Daniel Claassen
2020 Phase 1 NCT04246437 United States;
[F-18]PBR06
Brigham and Women's Hospital
2020 Early Phase 1 NCT04616456 United States;