201. Angelman syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 25 / Drugs : 40 - (DrugBank : 11) / Drug target genes : 22 - Drug target pathways : 20
Angelman syndrome and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
ID | Diseases (Sorted by score) | Score |
---|---|---|
201 | Angelman syndrome | - |
6 | Parkinson disease | 22.000 |
2 | Amyotrophic lateral sclerosis | 22.000 |
17 | Multiple system atrophy | 22.000 |
140 | Dorabe syndrome | 22.000 |
8 | Huntington disease | 16.995 |
152 | PCDH19 related syndrome | 16.000 |
206 | Fragile X syndrome | 15.818 |
5 | Progressive supranuclear palsy | 15.634 |
97 | Ulcerative colitis | 15.139 |
13 | Multiple sclerosis/Neuromyelitis optica | 14.949 |
21 | Mitochondrial disease | 14.534 |
205 | Fragile X syndrome related disease | 14.429 |
272 | Fibrodysplasia ossificans progressiva | 14.322 |
145 | West syndrome | 14.222 |
75 | Cushing disease | 14.196 |
70 | Spinal stenosis | 14.132 |
22 | Moyamoya disease | 14.130 |
155 | Acquired aphasia with convulsive disorder | 14.044 |
156 | Rett syndrome | 13.989 |
231 | Alpha-1-antitrypsin deficiency | 13.631 |
158 | Tuberous sclerosis | 13.631 |
46 | Malignant rheumatoid arthritis | 13.491 |
98 | Eosinophilic gastrointestinal disease | 13.339 |
18 | Spinocerebellar degeneration | 13.188 |
296 | Biliary atresia | 13.188 |
36 | Epidermolysis bullosa | 13.061 |
144 | Lennox-Gastaut syndrome | 13.061 |
193 | Prader-Willi syndrome | 13.005 |
298 | Hereditary pancreatitis | 12.954 |
3 | Spinal muscular atrophy | 12.954 |
84 | Sarcoidosis | 12.488 |
34 | Neurofibromatosis | 12.439 |
96 | Crohn disease | 12.052 |
7 | Corticobasal degeneration | 3.283 |
4 | Primary lateral sclerosis | 3.014 |
164 | Oculocutaneous albinism | 2.406 |
309 | Progressive myoclonus epilepsy | 2.352 |
74 | Prolactin secreting pituitary adenoma | 2.344 |
90 | Retinitis pigmentosa | 2.171 |
299 | Cystic fibrosis | 1.338 |