235. Hypoparathyroidism Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 88 / Drugs : 107 - (DrugBank : 24) / Drug target genes : 5 - Drug target pathways : 7
Drugs and their primary sponsors and trial info
100mcg rhPTH(1-84)
Shire
2017 Phase 1 NCT02781844 Canada;Denmark;Hungary;United States;
25mcg rhPTH(1-84)
Shire
2017 Phase 1 NCT02781844 Canada;Denmark;Hungary;United States;
50mcg rhPTH(1-84)
Shire
2017 Phase 1 NCT02781844 Canada;Denmark;Hungary;United States;
A: PTH (1-84)
University of Aarhus
2008 Phase 2 NCT00730210 Denmark;
AZP-3601
Amolyt Pharma
2020 Phase 1 NCT05239221 Hungary;Netherlands;
Alfacalcidol
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Allogenic parathyroid cells
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
2022 Phase 1/Phase 2 NCT05186883 -
Amorphous calcium carbonate
Amorphical Ltd.
2013 Phase 1/Phase 2 NCT01815021 Israel;
Autofluorescent detection + Injection of indocyanine green
Onze Lieve Vrouw Hospital
2021 Phase 3 NCT05117853 Belgium;
Blood sample
Hospices Civils de Lyon
2021 - NCT04671719 France;
CLTX-305
National Institute of Dental and Craniofacial Research (NIDCR)
2020 Phase 2 NCT04465227 United States;
Calcitriol
CHU de Quebec-Universite Laval
2017 - NCT03249012 Canada;
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
2021 Phase 1-2 ChiCTR2100041719 China;
Calcitriol & Calcium
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1991 Phase 2 NCT00001304 United States;
Calcium
Hospices Civils de Lyon
2019 - NCT04126941 France;
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
2021 Phase 1-2 ChiCTR2100041719 China;
West China Hospital, Sichuan University
2019 - ChiCTR1900022194 China;
Calcium carbonate
CHU de Quebec-Universite Laval
2017 - NCT03249012 Canada;
Hokusetsu ROD Study Group
2006 - JPRN-UMIN000000475 Japan;
Calcium carbonate and alphacalcidol
University of Athens
2017 - NCT04146259 Greece;
Calcium gluconate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Calcium lactate
kawasaki medicak school
2009 Phase 3 JPRN-UMIN000002155 Japan;
Combination Product: TransCon PTH
Ascendis Pharma A/S
2019 Phase 2 NCT04009291 Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 NCT04701203 Canada;Denmark;Germany;Hungary;Italy;Norway;United States;
Control group
University Hospital, Brest
2021 Phase 3 NCT04785443 France;
Crystalline calcium supplements
Amorphical Ltd.
2013 Phase 1/Phase 2 NCT01815021 Israel;
Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland).
Medical University of Lodz
2020 Phase 4 NCT04412694 Poland;
EB612 (EBP05)
Entera Bio Ltd.
2018 Phase 2 NCT03516773 Israel;
ESIDREX-R
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
EnteraBio's Oral Parathyroid Hormone (1-34)
Entera Bio Ltd.
2014 Phase 2 NCT02152228 Israel;
FORSTEO-R
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
Gold standard of visual identification and evaluation of viability of the parathyroid glands.
Onze Lieve Vrouw Hospital
2021 Phase 3 NCT05117853 Belgium;
Human recombinant parathyroid Hormone
Shire Human Genetic Therapies, Inc.
2018 Phase 3 EUCTR2017-003067-36-HU Canada;Denmark;Hungary;United States;
2018 Phase 3 EUCTR2017-003067-36-DK Canada;Denmark;Hungary;United States;
Human recombinant parathyroid hormone
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Hydrochlorothiazide
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
ICG
University Hospital, Brest
2021 Phase 3 NCT04785443 France;
INN Parathyroid Hormone (1-84) human
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
Immediate post operative bioassay of Parathyroid Hormone
Centre Hospitalier Universitaire de Nimes
2012 - NCT02924532 -
Infracyanine
CHRU de Brest
2021 Phase 3 EUCTR2020-005189-32-FR France;
Magnesium
University of Tartu
2009 - NCT00824226 Estonia;
NATPARA/NATPAR
Entera Bio Ltd.
2018 Phase 2 NCT03516773 Israel;
NPSP 558
NPS PHARMACEUTICALS
2009 - EUCTR2008-005063-34-IT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
2011 - EUCTR2011-001265-40-HU Hungary;
2010 - EUCTR2008-005063-34-LT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2010 - EUCTR2008-005063-34-HU Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 Phase 3 EUCTR2008-005063-34-GB Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-FR Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-DK Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2008 Phase 3 EUCTR2008-005063-34-BE Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
NPSP558
Shire
2011 Phase 3 NCT01455181 Hungary;
2011 Phase 3 NCT01297309 United States;
2011 Phase 3 NCT01268098 United States;
2008 Phase 3 NCT00732615 Belgium;Canada;Denmark;France;Hungary;Italy;United Kingdom;United States;
Natpar
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Natpara
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-IT Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3 EUCTR2017-003067-36-HU Canada;Denmark;Hungary;United States;
2018 Phase 3 EUCTR2017-003067-36-DK Canada;Denmark;Hungary;United States;
Near-infrared-induced autofluorescence and indocyanine green near-infrared angiography
Odense University Hospital
2021 - NCT05130476 Denmark;
ORMONE PARATIROIDEO DA DNA RICOMBINANTE
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-IT Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Open-label PTH(1-84)
John P. Bilezikian
2009 Phase 3 NCT01199614 United States;
PCO371
Chugai Pharmaceutical
2020 Phase 1 NCT04209179 Canada;Hungary;United States;
POLY(OXY-1,2-ETHANEDIYL), A
Ascendis Pharma Bone Diseases A/S
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-[[6-[[1-[3-[[3-(2,3-DIHYDROXYPROPOXY)PROPYL]AMINO]-3-OXOPROPYL]-2,5-DI
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-[[6-[[1-[3-[[3-(2,3-DIHYDROXYPROPOXY)PROPYL]AMINO]-3-OXOPROPYL]-2,5-DIOXO-3-PYRROLIDINYL]THIO]HEXYL]AMINO]ETHYL]AMINO]CARBONYL]-2-METHYLALANYL-TERIPARATIDE (2:1)
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
PTH
CHU de Quebec-Universite Laval
2017 - NCT03249012 Canada;
Chessler D. Steven
2021 Phase 3 JPRN-jRCT2051210058 Japan;
Hospital de Niños R. Gutierrez de Buenos Aires
2014 - NCT04690842 -
John P. Bilezikian
2004 Phase 2/Phase 3 NCT00473265 United States;
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
2021 Phase 1-2 ChiCTR2100041719 China;
kawasaki medicak school
2009 Phase 3 JPRN-UMIN000002155 Japan;
PTH 1-34
National Institute of Dental and Craniofacial Research (NIDCR)
2006 Phase 3 NCT00395538 Austria;Italy;United States;
PTH1-84 in parent study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
2010 Phase 3 NCT00856401 United States;
Palopegteriparatide
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
Parathyroid Hormone (1-84) Human Recombinant
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
Parathyroid Hormone (rDNA)
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
Parathyroid hormon 1-84
University of Bergen
2016 Early Phase 1 NCT02986607 Norway;
Parathyroid hormone
Takeda Pharmaceutical Company Limited
2021 Phase 3 JPRN-JapicCTI-194828 Japan;
Parathyroid hormone (rdna)
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
Parathyroideahormon
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
Phosphate
Hokusetsu ROD Study Group
2006 - JPRN-UMIN000000475 Japan;
Phosphate and betamethasone acetate, 2 mL.
Hospital Italiano de Buenos Aires
2016 Phase 4 NCT02652884 Argentina;
Potassium sparing diuretic
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Preotact
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
RECOMBINANT HUMAN PARATHYROID HORMONE (1-84)
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Rcombinant Human Parathyroid Hormone [rhPTH(1-84)]
NPS Pharmaceuticals, Inc.
2010 - EUCTR2008-005063-34-LT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2010 - EUCTR2008-005063-34-HU Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 Phase 3 EUCTR2008-005063-34-GB Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-FR Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-DK Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2008 Phase 3 EUCTR2008-005063-34-BE Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
Recombinant Human Parathyroid Hormone [rhPTH(1-84)]
NPS Pharmaceuticals, Inc.
2011 - EUCTR2011-001265-40-HU Hungary;
2010 - EUCTR2008-005063-34-LT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2010 - EUCTR2008-005063-34-HU Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 Phase 3 EUCTR2008-005063-34-GB Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-FR Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-DK Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2008 Phase 3 EUCTR2008-005063-34-BE Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
RhPTH (1-84)
Takeda Pharmaceutical Company Limited
2021 Phase 3 JPRN-JapicCTI-194828 Japan;
RhPTH(1-84)
Shire
2022 Phase 3 NCT03878953 Japan;
2018 Phase 4 NCT03324880 Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3 NCT03364738 Canada;Denmark;Hungary;United States;
2017 Phase 1 NCT03150108 United States;
2016 Phase 4 NCT02910466 United States;
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3 EUCTR2017-003067-36-HU Canada;Denmark;Hungary;United States;
2018 Phase 3 EUCTR2017-003067-36-DK Canada;Denmark;Hungary;United States;
SUB21634
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
Saline NaCl
Hospital Italiano de Buenos Aires
2016 Phase 4 NCT02652884 Argentina;
Sevelamer
Hokusetsu ROD Study Group
2006 - JPRN-UMIN000000475 Japan;
Sodium citrate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Synthetic Human Parathyroid Hormone 1-34
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2008 Early Phase 1 NCT00743782 United States;
1991 Phase 2 NCT00001304 United States;
Te
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
Teriparatide
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Mayo Clinic
2010 Phase 2 NCT01171690 United States;
Saint Petersburg State University, Russia
2021 Phase 3 NCT04750460 Russian Federation;
The Seventh Medical Center, PLA General Hospital
2021 - ChiCTR2100047758 China;
Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleava
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleavable linker
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
Thiazide
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Thymus/Parathyroid Transplantation
M. Louise Markert
2005 Phase 1 NCT00566488 United States;
Total thyroidectomy
Medical University of Lodz
2020 Phase 4 NCT04412694 Poland;
TransCon PTH high-dose pen
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
TransCon PTH low-dose pen
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
TransCon PTH mid-dose pen
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
Tériparatide
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
UN-ALPHA-R 0.25µg
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
Verde de Indocianina (Indocyanine Green)
Hospital Universitari Son Espases
2020 Phase 4 EUCTR2019-003506-26-ES Spain;
Vitamin D
University of Wisconsin, Madison
2005 Phase 4 NCT00581828 United States;
West China Hospital, Sichuan University
2019 - ChiCTR1900022194 China;
Shire
2017 Phase 1 NCT02781844 Canada;Denmark;Hungary;United States;
25mcg rhPTH(1-84)
Shire
2017 Phase 1 NCT02781844 Canada;Denmark;Hungary;United States;
50mcg rhPTH(1-84)
Shire
2017 Phase 1 NCT02781844 Canada;Denmark;Hungary;United States;
A: PTH (1-84)
University of Aarhus
2008 Phase 2 NCT00730210 Denmark;
AZP-3601
Amolyt Pharma
2020 Phase 1 NCT05239221 Hungary;Netherlands;
Alfacalcidol
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Allogenic parathyroid cells
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
2022 Phase 1/Phase 2 NCT05186883 -
Amorphous calcium carbonate
Amorphical Ltd.
2013 Phase 1/Phase 2 NCT01815021 Israel;
Autofluorescent detection + Injection of indocyanine green
Onze Lieve Vrouw Hospital
2021 Phase 3 NCT05117853 Belgium;
Blood sample
Hospices Civils de Lyon
2021 - NCT04671719 France;
CLTX-305
National Institute of Dental and Craniofacial Research (NIDCR)
2020 Phase 2 NCT04465227 United States;
Calcitriol
CHU de Quebec-Universite Laval
2017 - NCT03249012 Canada;
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
2021 Phase 1-2 ChiCTR2100041719 China;
Calcitriol & Calcium
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
1991 Phase 2 NCT00001304 United States;
Calcium
Hospices Civils de Lyon
2019 - NCT04126941 France;
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
2021 Phase 1-2 ChiCTR2100041719 China;
West China Hospital, Sichuan University
2019 - ChiCTR1900022194 China;
Calcium carbonate
CHU de Quebec-Universite Laval
2017 - NCT03249012 Canada;
Hokusetsu ROD Study Group
2006 - JPRN-UMIN000000475 Japan;
Calcium carbonate and alphacalcidol
University of Athens
2017 - NCT04146259 Greece;
Calcium gluconate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Calcium lactate
kawasaki medicak school
2009 Phase 3 JPRN-UMIN000002155 Japan;
Combination Product: TransCon PTH
Ascendis Pharma A/S
2019 Phase 2 NCT04009291 Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 NCT04701203 Canada;Denmark;Germany;Hungary;Italy;Norway;United States;
Control group
University Hospital, Brest
2021 Phase 3 NCT04785443 France;
Crystalline calcium supplements
Amorphical Ltd.
2013 Phase 1/Phase 2 NCT01815021 Israel;
Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland).
Medical University of Lodz
2020 Phase 4 NCT04412694 Poland;
EB612 (EBP05)
Entera Bio Ltd.
2018 Phase 2 NCT03516773 Israel;
ESIDREX-R
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
EnteraBio's Oral Parathyroid Hormone (1-34)
Entera Bio Ltd.
2014 Phase 2 NCT02152228 Israel;
FORSTEO-R
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
Gold standard of visual identification and evaluation of viability of the parathyroid glands.
Onze Lieve Vrouw Hospital
2021 Phase 3 NCT05117853 Belgium;
Human recombinant parathyroid Hormone
Shire Human Genetic Therapies, Inc.
2018 Phase 3 EUCTR2017-003067-36-HU Canada;Denmark;Hungary;United States;
2018 Phase 3 EUCTR2017-003067-36-DK Canada;Denmark;Hungary;United States;
Human recombinant parathyroid hormone
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Hydrochlorothiazide
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
ICG
University Hospital, Brest
2021 Phase 3 NCT04785443 France;
INN Parathyroid Hormone (1-84) human
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
Immediate post operative bioassay of Parathyroid Hormone
Centre Hospitalier Universitaire de Nimes
2012 - NCT02924532 -
Infracyanine
CHRU de Brest
2021 Phase 3 EUCTR2020-005189-32-FR France;
Magnesium
University of Tartu
2009 - NCT00824226 Estonia;
NATPARA/NATPAR
Entera Bio Ltd.
2018 Phase 2 NCT03516773 Israel;
NPSP 558
NPS PHARMACEUTICALS
2009 - EUCTR2008-005063-34-IT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
2011 - EUCTR2011-001265-40-HU Hungary;
2010 - EUCTR2008-005063-34-LT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2010 - EUCTR2008-005063-34-HU Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 Phase 3 EUCTR2008-005063-34-GB Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-FR Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-DK Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2008 Phase 3 EUCTR2008-005063-34-BE Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
NPSP558
Shire
2011 Phase 3 NCT01455181 Hungary;
2011 Phase 3 NCT01297309 United States;
2011 Phase 3 NCT01268098 United States;
2008 Phase 3 NCT00732615 Belgium;Canada;Denmark;France;Hungary;Italy;United Kingdom;United States;
Natpar
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Natpara
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-IT Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3 EUCTR2017-003067-36-HU Canada;Denmark;Hungary;United States;
2018 Phase 3 EUCTR2017-003067-36-DK Canada;Denmark;Hungary;United States;
Near-infrared-induced autofluorescence and indocyanine green near-infrared angiography
Odense University Hospital
2021 - NCT05130476 Denmark;
ORMONE PARATIROIDEO DA DNA RICOMBINANTE
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-IT Belgium;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Open-label PTH(1-84)
John P. Bilezikian
2009 Phase 3 NCT01199614 United States;
PCO371
Chugai Pharmaceutical
2020 Phase 1 NCT04209179 Canada;Hungary;United States;
POLY(OXY-1,2-ETHANEDIYL), A
Ascendis Pharma Bone Diseases A/S
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-[[6-[[1-[3-[[3-(2,3-DIHYDROXYPROPOXY)PROPYL]AMINO]-3-OXOPROPYL]-2,5-DI
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
POLY(OXY-1,2-ETHANEDIYL), ALPHA-HYDRO-OMEGA-METHOXY, ETHER WITH N-[[[2-[[6-[[1-[3-[[3-(2,3-DIHYDROXYPROPOXY)PROPYL]AMINO]-3-OXOPROPYL]-2,5-DIOXO-3-PYRROLIDINYL]THIO]HEXYL]AMINO]ETHYL]AMINO]CARBONYL]-2-METHYLALANYL-TERIPARATIDE (2:1)
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
PTH
CHU de Quebec-Universite Laval
2017 - NCT03249012 Canada;
Chessler D. Steven
2021 Phase 3 JPRN-jRCT2051210058 Japan;
Hospital de Niños R. Gutierrez de Buenos Aires
2014 - NCT04690842 -
John P. Bilezikian
2004 Phase 2/Phase 3 NCT00473265 United States;
Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
2021 Phase 1-2 ChiCTR2100041719 China;
kawasaki medicak school
2009 Phase 3 JPRN-UMIN000002155 Japan;
PTH 1-34
National Institute of Dental and Craniofacial Research (NIDCR)
2006 Phase 3 NCT00395538 Austria;Italy;United States;
PTH1-84 in parent study
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
2010 Phase 3 NCT00856401 United States;
Palopegteriparatide
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
Parathyroid Hormone (1-84) Human Recombinant
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
Parathyroid Hormone (rDNA)
NPS Pharmaceuticals, Inc.
2015 Phase 1 EUCTR2015-003108-22-GB United Kingdom;
Parathyroid hormon 1-84
University of Bergen
2016 Early Phase 1 NCT02986607 Norway;
Parathyroid hormone
Takeda Pharmaceutical Company Limited
2021 Phase 3 JPRN-JapicCTI-194828 Japan;
Parathyroid hormone (rdna)
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
Parathyroideahormon
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
Phosphate
Hokusetsu ROD Study Group
2006 - JPRN-UMIN000000475 Japan;
Phosphate and betamethasone acetate, 2 mL.
Hospital Italiano de Buenos Aires
2016 Phase 4 NCT02652884 Argentina;
Potassium sparing diuretic
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Preotact
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
RECOMBINANT HUMAN PARATHYROID HORMONE (1-84)
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
Rcombinant Human Parathyroid Hormone [rhPTH(1-84)]
NPS Pharmaceuticals, Inc.
2010 - EUCTR2008-005063-34-LT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2010 - EUCTR2008-005063-34-HU Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 Phase 3 EUCTR2008-005063-34-GB Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-FR Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-DK Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2008 Phase 3 EUCTR2008-005063-34-BE Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
Recombinant Human Parathyroid Hormone [rhPTH(1-84)]
NPS Pharmaceuticals, Inc.
2011 - EUCTR2011-001265-40-HU Hungary;
2010 - EUCTR2008-005063-34-LT Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2010 - EUCTR2008-005063-34-HU Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 Phase 3 EUCTR2008-005063-34-GB Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-FR Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2009 - EUCTR2008-005063-34-DK Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
2008 Phase 3 EUCTR2008-005063-34-BE Belgium;Denmark;France;Hungary;Italy;Lithuania;United Kingdom;
RhPTH (1-84)
Takeda Pharmaceutical Company Limited
2021 Phase 3 JPRN-JapicCTI-194828 Japan;
RhPTH(1-84)
Shire
2022 Phase 3 NCT03878953 Japan;
2018 Phase 4 NCT03324880 Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3 NCT03364738 Canada;Denmark;Hungary;United States;
2017 Phase 1 NCT03150108 United States;
2016 Phase 4 NCT02910466 United States;
Shire Human Genetic Therapies, Inc.
2018 Phase 3;Phase 4 EUCTR2017-000284-32-SE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-PT Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-NL Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-GB Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-DK Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3;Phase 4 EUCTR2017-000284-32-BE Belgium;Canada;Denmark;France;Germany;Italy;Netherlands;Norway;Portugal;Spain;Sweden;United Kingdom;United States;
2018 Phase 3 EUCTR2017-003067-36-HU Canada;Denmark;Hungary;United States;
2018 Phase 3 EUCTR2017-003067-36-DK Canada;Denmark;Hungary;United States;
SUB21634
Aarhus University Hospital, Dept of Endocrinology and Metabolism C
2008 Phase 4 EUCTR2008-000606-36-DK Denmark;
Saline NaCl
Hospital Italiano de Buenos Aires
2016 Phase 4 NCT02652884 Argentina;
Sevelamer
Hokusetsu ROD Study Group
2006 - JPRN-UMIN000000475 Japan;
Sodium citrate
National Center for Research Resources (NCRR)
1995 - NCT00004361 -
Synthetic Human Parathyroid Hormone 1-34
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
2008 Early Phase 1 NCT00743782 United States;
1991 Phase 2 NCT00001304 United States;
Te
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
Teriparatide
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Mayo Clinic
2010 Phase 2 NCT01171690 United States;
Saint Petersburg State University, Russia
2021 Phase 3 NCT04750460 Russian Federation;
The Seventh Medical Center, PLA General Hospital
2021 - ChiCTR2100047758 China;
Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleava
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleavable linker
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
Thiazide
Assistance Publique - Hôpitaux de Paris
2017 Phase 2 NCT02824718 France;
Thymus/Parathyroid Transplantation
M. Louise Markert
2005 Phase 1 NCT00566488 United States;
Total thyroidectomy
Medical University of Lodz
2020 Phase 4 NCT04412694 Poland;
TransCon PTH high-dose pen
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
TransCon PTH low-dose pen
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
TransCon PTH mid-dose pen
Ascendis Pharma Bone Disease A/S
2021 Phase 3 EUCTR2020-003380-26-IT Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-IT Canada;Denmark;Germany;Italy;United Kingdom;United States;
Ascendis Pharma Bone Diseases A/S
2021 Phase 3 EUCTR2020-003380-26-HU Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-FR Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DK Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2021 Phase 3 EUCTR2020-003380-26-DE Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2020 Phase 3 EUCTR2020-003380-26-NO Canada;Denmark;France;Germany;Hungary;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-NO Canada;Denmark;Germany;Italy;Norway;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-GB Canada;Denmark;Germany;United Kingdom;United States;
2019 Phase 2 EUCTR2018-004815-33-DK Canada;Denmark;Germany;United Kingdom;United States;
- Phase 2 EUCTR2018-004815-33-DE Canada;Denmark;Germany;United States;
Tériparatide
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
UN-ALPHA-R 0.25µg
ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS (AP-HP)
2016 Phase 2 EUCTR2016-000500-29-FR France;
Verde de Indocianina (Indocyanine Green)
Hospital Universitari Son Espases
2020 Phase 4 EUCTR2019-003506-26-ES Spain;
Vitamin D
University of Wisconsin, Madison
2005 Phase 4 NCT00581828 United States;
West China Hospital, Sichuan University
2019 - ChiCTR1900022194 China;