302. Leber hereditary optic neuropathy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 23 / Drugs : 15 - (DrugBank : 5) / Drug target genes : 5 - Drug target pathways : 33
Leber hereditary optic neuropathy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 302 | Leber hereditary optic neuropathy | - |
| 326 | Osteopetrosis | 5.000 |
| 13 | Multiple sclerosis/Neuromyelitis optica | 5.000 |
| 6 | Parkinson disease | 5.000 |
| 299 | Cystic fibrosis | 5.000 |
| 20 | Adrenoleukodystrophy | 5.000 |
| 2 | Amyotrophic lateral sclerosis | 5.000 |
| 62 | Paroxysmal nocturnal hemoglobinuria | 5.000 |
| 63 | Idiopathic thrombocytopenic purpura | 5.000 |
| 36 | Epidermolysis bullosa | 5.000 |
| 39 | Toxic epidermal necrolysis | 5.000 |
| 160 | Congenital ichthyosis | 5.000 |
| 19 | Lysosomal storage disease | 5.000 |
| 46 | Malignant rheumatoid arthritis | 5.000 |
| 49 | Systemic lupus erythematosus | 5.000 |
| 51 | Scleroderma | 5.000 |
| 60 | Aplastic anemia | 5.000 |
| 61 | Autoimmune hemolytic anemia | 5.000 |
| 65 | Primary immunodeficiency | 5.000 |
| 66 | IgA nephropathy | 5.000 |
| 85 | Idiopathic interstitial pneumonia | 5.000 |
| 96 | Crohn disease | 5.000 |
| 158 | Tuberous sclerosis | 5.000 |
| 222 | Primary nephrotic syndrome | 5.000 |
| 283 | Acquired pure red cell aplasia | 5.000 |
| 285 | Fanconi anemia | 5.000 |
| 53 | Sjogren syndrome | 5.000 |
| 26 | HTLV-1-associated myelopathy | 5.000 |
| 28 | Systemic amyloidosis | 5.000 |
| 162 | Pemphigoid | 5.000 |
| 228 | Bronchiolitis obliterans | 5.000 |
| 90 | Retinitis pigmentosa | 5.000 |
| 113 | Muscular dystrophy | 5.000 |
| 227 | Osler disease | 5.000 |
| 93 | Primary biliary cholangitis | 5.000 |
| 38 | Stevens-Johnson syndrome | 5.000 |
| 50 | Dermatomyositis | 5.000 |
| 56 | Behcet disease | 5.000 |
| 107 | Juvenile idiopathic arthritis | 5.000 |
| 97 | Ulcerative colitis | 5.000 |
| 58 | Hypertrophic cardiomyopathy | 5.000 |
| 164 | Oculocutaneous albinism | 5.000 |
| 40 | Takayasu arteritis | 5.000 |
| 41 | Giant cell arteritis | 5.000 |
| 151 | Rasmussen encephalitis | 5.000 |
| 226 | Interstitial cystitis with Hunners ulcer | 5.000 |
| 269 | Pyogenic arthritis | 5.000 |
| 42 | Polyarteritis nodosa | 5.000 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 5.000 |
| 55 | Relapsing polychondritis | 5.000 |
| 95 | Autoimmune hepatitis | 5.000 |
| 284 | Diamond-Blackfan anemia | 5.000 |
| 11 | Myasthenia gravis | 5.000 |
| 224 | Purpura nephritis | 5.000 |
| 274 | Osteogenesis Imperfecta | 5.000 |
| 286 | Hereditary sideroblastic anemia | 5.000 |
| 64 | Thrombotic thrombocytopenic purpura | 5.000 |
| 234 | Peroxisomal disease (except Adrenoleukodystrophy) | 5.000 |