38. Stevens-Johnson syndrome Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 17 / Drugs : 29 - (DrugBank : 9) / Drug target genes : 15 - Drug target pathways : 101
Drugs and their primary sponsors and trial info
6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
Imperial College London
2012 Phase 4 EUCTR2012-003136-23-GB United Kingdom;
Cultivated oral mucosal epithelial sheet transplantation
Seoul National University Hospital
2014 Phase 1/Phase 2 NCT02149732 Korea, Republic of;
Cyclosporine 5 mg/kg bid days 0-14
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Etanercept
Abe Riichirou
2021 Phase 2 JPRN-jRCTs031210325 Japan;
Etanercept 50 mg sc day 0 and day 3
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Harmonized supportive care
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Infliximab
Massachusetts Eye and Ear Infirmary
2010 Phase 1/Phase 2 NCT01256489 United States;
Intravenous immunoglobulin
Nihon Pharmaceutical Co., Ltd
2012 Phase 3 NCT01696500 Japan;
Lamotrigine - generic product
Imperial College London
2012 Phase 4 EUCTR2012-003136-23-GB United Kingdom;
Methylprednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
Palifermin
Brett King
2010 Phase 1/Phase 2 NCT02037347 United States;
Prednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
Riboflavin
Joseph B. Ciolino, MD
2012 Phase 1/Phase 2 NCT01582880 United States;
Site specific standard of care comparison
Massachusetts General Hospital
2021 - NCT03585946 -
Topical infliximab
James Chodosh, MD, MPH
2014 Phase 1/Phase 2 NCT02126020 Canada;United States;
cyclosporin eye drop
Mahidol University
2007 Phase 4 NCT01488396 Thailand;
Imperial College London
2012 Phase 4 EUCTR2012-003136-23-GB United Kingdom;
Cultivated oral mucosal epithelial sheet transplantation
Seoul National University Hospital
2014 Phase 1/Phase 2 NCT02149732 Korea, Republic of;
Cyclosporine 5 mg/kg bid days 0-14
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Etanercept
Abe Riichirou
2021 Phase 2 JPRN-jRCTs031210325 Japan;
Etanercept 50 mg sc day 0 and day 3
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Harmonized supportive care
Vanderbilt University Medical Center
2022 Phase 3 NCT02987257 United States;
Infliximab
Massachusetts Eye and Ear Infirmary
2010 Phase 1/Phase 2 NCT01256489 United States;
Intravenous immunoglobulin
Nihon Pharmaceutical Co., Ltd
2012 Phase 3 NCT01696500 Japan;
Lamotrigine - generic product
Imperial College London
2012 Phase 4 EUCTR2012-003136-23-GB United Kingdom;
Methylprednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
Palifermin
Brett King
2010 Phase 1/Phase 2 NCT02037347 United States;
Prednisolone
Morita Eishin
2017 Phase 2 JPRN-jRCTs061180044 Germany;Japan;Taiwan;
Riboflavin
Joseph B. Ciolino, MD
2012 Phase 1/Phase 2 NCT01582880 United States;
Site specific standard of care comparison
Massachusetts General Hospital
2021 - NCT03585946 -
Topical infliximab
James Chodosh, MD, MPH
2014 Phase 1/Phase 2 NCT02126020 Canada;United States;
cyclosporin eye drop
Mahidol University
2007 Phase 4 NCT01488396 Thailand;