5. Progressive supranuclear palsy Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 89 / Drugs : 107 - (DrugBank : 40) / Drug target genes : 65 - Drug target pathways : 108
Progressive supranuclear palsy and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability
ID | Diseases (Sorted by drug repositionability) |
---|---|
5 | Progressive supranuclear palsy |
6 | Parkinson disease |
13 | Multiple sclerosis/Neuromyelitis optica |
2 | Amyotrophic lateral sclerosis |
17 | Multiple system atrophy |
3 | Spinal muscular atrophy |
206 | Fragile X syndrome |
8 | Huntington disease |
156 | Rett syndrome |
22 | Moyamoya disease |
70 | Spinal stenosis |
18 | Spinocerebellar degeneration |
46 | Malignant rheumatoid arthritis |
97 | Ulcerative colitis |
96 | Crohn disease |
21 | Mitochondrial disease |
140 | Dorabe syndrome |
193 | Prader-Willi syndrome |
205 | Fragile X syndrome related disease |
34 | Neurofibromatosis |
296 | Biliary atresia |
144 | Lennox-Gastaut syndrome |
158 | Tuberous sclerosis |
152 | PCDH19 related syndrome |
201 | Angelman syndrome |
98 | Eosinophilic gastrointestinal disease |
203 | 22q11.2 deletion syndrome |
231 | Alpha-1-antitrypsin deficiency |
145 | West syndrome |
127 | Frontotemporal lobar degeneration |
215 | Tetralogy of Fallot |
272 | Fibrodysplasia ossificans progressiva |
155 | Acquired aphasia with convulsive disorder |
298 | Hereditary pancreatitis |
169 | Menkes disease |
170 | Occipital horn syndrome |
36 | Epidermolysis bullosa |
113 | Muscular dystrophy |
75 | Cushing disease |
85 | Idiopathic interstitial pneumonia |
102 | Rubinstein-Taybi syndrome |
86 | Pulmonary arterial hypertension |
84 | Sarcoidosis |
118 | Myelomeningocele |
4 | Primary lateral sclerosis |
26 | HTLV-1-associated myelopathy |
256 | Muscle glycogenosis |
254 | Porphyria |
11 | Myasthenia gravis |
233 | Wolfram syndrome |
226 | Interstitial cystitis with Hunners ulcer |
89 | Lymphangioleiomyomatosis |
90 | Retinitis pigmentosa |
7 | Corticobasal degeneration |
78 | Hypopituitarism |
65 | Primary immunodeficiency |
299 | Cystic fibrosis |
58 | Hypertrophic cardiomyopathy |
323 | Aromatic L-amino acid decarboxylase deficiency |
57 | Idiopathic dilated cardiomyopathy |
280 | Huge arteriovenous malformation with cervicofacial or limb lesion |
222 | Primary nephrotic syndrome |
288 | Autoimmune acquired coagulation factor deficiency |
331 | Idiopathic multicentric castleman disease |
210 | Single Ventricle |
337 | Homocystinuria |
49 | Systemic lupus erythematosus |
278 | Huge lymphatic malformation with cervicofacial lesion |
212 | Tricuspid atresia |
107 | Juvenile idiopathic arthritis |
53 | Sjogren syndrome |
51 | Scleroderma |
149 | Hemiconvulsion hemiplegia epilepsy syndrome |
28 | Systemic amyloidosis |
251 | Urea cycle disorder |
19 | Lysosomal storage disease |
111 | Congenital myopathy |