DR info

Clinical trials : 2,307 / Drugs : 2,007 - (DrugBank : 349) / Drug target genes : 188 - Drug target pathways : 199

Parkinson disease and other diseases between which drug repositioning might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Drug repositionability

ID	Diseases (Sorted by drug repositionability)
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
2	Amyotrophic lateral sclerosis
97	Ulcerative colitis
46	Malignant rheumatoid arthritis
8	Huntington disease
96	Crohn disease
5	Progressive supranuclear palsy
17	Multiple system atrophy
206	Fragile X syndrome
70	Spinal stenosis
21	Mitochondrial disease
140	Dorabe syndrome
156	Rett syndrome
193	Prader-Willi syndrome
3	Spinal muscular atrophy
144	Lennox-Gastaut syndrome
86	Pulmonary arterial hypertension
296	Biliary atresia
298	Hereditary pancreatitis
18	Spinocerebellar degeneration
226	Interstitial cystitis with Hunners ulcer
84	Sarcoidosis
158	Tuberous sclerosis
299	Cystic fibrosis
36	Epidermolysis bullosa
113	Muscular dystrophy
231	Alpha-1-antitrypsin deficiency
127	Frontotemporal lobar degeneration
22	Moyamoya disease
34	Neurofibromatosis
85	Idiopathic interstitial pneumonia
145	West syndrome
98	Eosinophilic gastrointestinal disease
201	Angelman syndrome
90	Retinitis pigmentosa
78	Hypopituitarism
51	Scleroderma
107	Juvenile idiopathic arthritis
205	Fragile X syndrome related disease
58	Hypertrophic cardiomyopathy
272	Fibrodysplasia ossificans progressiva
4	Primary lateral sclerosis
152	PCDH19 related syndrome
75	Cushing disease
11	Myasthenia gravis
256	Muscle glycogenosis
65	Primary immunodeficiency
215	Tetralogy of Fallot
203	22q11.2 deletion syndrome
67	Polycystic kidney disease
49	Systemic lupus erythematosus
28	Systemic amyloidosis
19	Lysosomal storage disease
155	Acquired aphasia with convulsive disorder
222	Primary nephrotic syndrome
89	Lymphangioleiomyomatosis
63	Idiopathic thrombocytopenic purpura
233	Wolfram syndrome
26	HTLV-1-associated myelopathy
265	Lipodystrophy
66	IgA nephropathy
38	Stevens-Johnson syndrome
254	Porphyria
169	Menkes disease
170	Occipital horn syndrome
271	Ankylosing spondylitis
149	Hemiconvulsion hemiplegia epilepsy syndrome
50	Dermatomyositis
162	Pemphigoid
118	Myelomeningocele
53	Sjogren syndrome
164	Oculocutaneous albinism
57	Idiopathic dilated cardiomyopathy
179	Williams syndrome
102	Rubinstein-Taybi syndrome
283	Acquired pure red cell aplasia
45	Eosinophilic granulomatosis with Polyangiitis
288	Autoimmune acquired coagulation factor deficiency
81	Congenital adrenal hyperplasia
95	Autoimmune hepatitis
41	Giant cell arteritis
167	Marfan syndrome
225	Congenital nephrogenic diabetes insipidus
280	Huge arteriovenous malformation with cervicofacial or limb lesion
10	Charcot-Marie-Tooth disease
20	Adrenoleukodystrophy
224	Purpura nephritis
56	Behcet disease
236	Pseudohypoparathyroidism
285	Fanconi anemia
64	Thrombotic thrombocytopenic purpura
61	Autoimmune hemolytic anemia
42	Polyarteritis nodosa
157	Sturge-Weber syndrome
278	Huge lymphatic malformation with cervicofacial lesion
12	Congenital myasthenic syndrome
302	Leber hereditary optic neuropathy
294	Congenital diaphragmatic hernia
1	Spinal and bulbar muscular atrophy
228	Bronchiolitis obliterans
35	Pemphigus
227	Osler disease
60	Aplastic anemia
93	Primary biliary cholangitis
40	Takayasu arteritis
331	Idiopathic multicentric castleman disease
210	Single Ventricle
14	Chronic inflammatory demyelinating polyneuropathy
151	Rasmussen encephalitis
62	Paroxysmal nocturnal hemoglobinuria
168	Ehlers-Danlos syndrome
7	Corticobasal degeneration
309	Progressive myoclonus epilepsy
72	Pituitary ADH secretion disorder
246	Methylmalonic acidemia
284	Diamond-Blackfan anemia
274	Osteogenesis Imperfecta
39	Toxic epidermal necrolysis
74	Prolactin secreting pituitary adenoma
286	Hereditary sideroblastic anemia
55	Relapsing polychondritis
234	Peroxisomal disease (except Adrenoleukodystrophy)
171	Wilson disease
310	Congenital anomalies syndrome
229	Autoimmune pulmonary alveolar proteinosis
323	Aromatic L-amino acid decarboxylase deficiency
114	Non-dystrophic myotonia syndrome
88	Chronic thromboembolic pulmonary hypertension
218	Alport syndrome
300	IgG4-related disease
269	Pyogenic arthritis
326	Osteopetrosis
87	Pulmonary veno-occlusive disease
251	Urea cycle disorder
202	Smith-Magenis syndrome
160	Congenital ichthyosis
212	Tricuspid atresia
77	Growth hormone secreting pituitary adenoma
337	Homocystinuria
263	Cerebrotendinous xanthomatosis
257	Hepatic glycogenosis
282	Congenital dyserythropoietic anemia
307	Canavan disease
120	Hereditary dystonia
43	Microscopic polyangiitis
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
15	Inclusion body myositis
230	Alveolar hypoventilation syndrome
94	Primary sclerosing cholangitis
187	Kabuki syndrome
44	Wegener granulomatosis
301	Macular dystrophy
333	Hutchinson-Gilford syndrome
91	Budd-Chiari syndrome
235	Hypoparathyroidism
71	Idiopathic osteonecrosis of the femoral head
137	Focal cortical dysplasia
192	Cockayne syndrome
277	Lymphangiomatosis
281	Klippel-Trenaunay-Weber syndrome
111	Congenital myopathy
241	Hypertyrosinemia type I
52	Mixed connective tissue disease
290	Chronic nonspecific multiple ulcers of the small intestine
220	Rapidly progressive glomerulonephritis
30	Distal myopathy