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KEGG GENES
KEGG PATHWAY
KEGG DRUG
DrugBank
Disease ID
1
SIGMAR1
💬
1. SIGMAR1
×
Name
Full Name
SIGMAR1
sigma non-opioid intracellular receptor 1
[2]
Amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis
,
Pathways of neurodegeneration - multiple diseases
Dextromethorphan
Dextromethorphan
💬
1. SIGMAR1
×
Name
Other Names
Dextromethorphan
Dextromethorphan (USP)
Dextromethorphan
[11]
2
2
,
6
,
8
,
13
,
21
,
46
,
78
,
85
,
96
,
97
,
156
💬
1. SIGMAR1
×
Disease ID
Name
2
Amyotrophic lateral sclerosis
6
Parkinson disease
8
Huntington disease
13
Multiple sclerosis/Neuromyelitis optica
21
Mitochondrial disease
46
Malignant rheumatoid arthritis
78
Hypopituitarism
85
Idiopathic interstitial pneumonia
96
Crohn disease
97
Ulcerative colitis
156
Rett syndrome
2
CYSLTR1
💬
2. CYSLTR1
×
Name
Full Name
CYSLTR1
cysteinyl leukotriene receptor 1
[2]
Calcium signaling pathway
Calcium signaling pathway
,
Neuroactive ligand-receptor interaction
Montelukast
Montelukast
💬
2. CYSLTR1
×
Name
Other Names
Montelukast
Montelukast (INN)
Brondilat (TN)
Montelukast
[8]
6
6
,
13
,
46
,
61
,
63
,
85
,
98
,
228
💬
2. CYSLTR1
×
Disease ID
Name
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
46
Malignant rheumatoid arthritis
61
Autoimmune hemolytic anemia
63
Idiopathic thrombocytopenic purpura
85
Idiopathic interstitial pneumonia
98
Eosinophilic gastrointestinal disease
228
Bronchiolitis obliterans
3
HRH3
💬
3. HRH3
×
Name
Full Name
HRH3
histamine receptor H3
[1]
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
Bavisant
Bavisant
💬
3. HRH3
×
Name
Other Names
Bavisant
Bavisant (USAN/INN)
Bavisant
[1]
6
6
💬
3. HRH3
×
Disease ID
Name
6
Parkinson disease
4
HRH3
💬
4. HRH3
×
Name
Full Name
HRH3
histamine receptor H3
[1]
Neuroactive ligand-receptor interaction
Neuroactive ligand-receptor interaction
Pitolisant
Pitolisant
💬
4. HRH3
×
Name
Other Names
Pitolisant
Pitolisant (USAN/INN)
Wakix (TN)
Ozawade (TN)
Pitolisant
[3]
6
6
,
113
,
193
💬
4. HRH3
×
Disease ID
Name
6
Parkinson disease
113
Muscular dystrophy
193
Prader-Willi syndrome
5
CHRM1
💬
5. CHRM1
×
Name
Full Name
CHRM1
cholinergic receptor muscarinic 1
[8]
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signaling pathway
,
Cholinergic synapse
,
Regulation of actin cytoskeleton
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
[8]
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K
...
Tropicamide
Tropicamide
💬
5. CHRM1
×
Name
Other Names
Tropicamide
Tropicamide (JP18/USP/INN)
Mydriacyl (TN)
Tropicamide
[1]
6
6
💬
5. CHRM1
×
Disease ID
Name
6
Parkinson disease
6
CHRM1
💬
6. CHRM1
×
Name
Full Name
CHRM1
cholinergic receptor muscarinic 1
[8]
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signaling pathway
,
Cholinergic synapse
,
Regulation of actin cytoskeleton
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
[8]
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K
...
Oxybutynin
Oxybutynin
💬
6. CHRM1
×
Name
Other Names
Oxybutynin
Oxybutynin (USAN/INN)
Anturol (TN)
Oxytrol (TN)
Oxybutynin
[3]
6
6
,
13
,
53
💬
6. CHRM1
×
Disease ID
Name
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
53
Sjogren syndrome
7
CHRM1
💬
7. CHRM1
×
Name
Full Name
CHRM1
cholinergic receptor muscarinic 1
[8]
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signaling pathway
,
Cholinergic synapse
,
Regulation of actin cytoskeleton
,
Alzheimer disease
,
Pathways of neurodegeneration - multiple diseases
[8]
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K
...
Trihexyphenidyl
Trihexyphenidyl
💬
7. CHRM1
×
Name
Other Names
Trihexyphenidyl
Trihexyphenidyl (INN)
Apo-trihex (TN)
Trihexyphenidyl
[2]
5
5
,
6
💬
7. CHRM1
×
Disease ID
Name
5
Progressive supranuclear palsy
6
Parkinson disease
8
CHRM2
💬
8. CHRM2
×
Name
Full Name
CHRM2
cholinergic receptor muscarinic 2
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signaling pathway
,
Cholinergic synapse
,
Regulation of actin cytoskeleton
[6]
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K
...
Tropicamide
Tropicamide
💬
8. CHRM2
×
Name
Other Names
Tropicamide
Tropicamide (JP18/USP/INN)
Mydriacyl (TN)
Tropicamide
[1]
6
6
💬
8. CHRM2
×
Disease ID
Name
6
Parkinson disease
9
CHRM2
💬
9. CHRM2
×
Name
Full Name
CHRM2
cholinergic receptor muscarinic 2
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signaling pathway
,
Cholinergic synapse
,
Regulation of actin cytoskeleton
[6]
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K
...
Oxybutynin
Oxybutynin
💬
9. CHRM2
×
Name
Other Names
Oxybutynin
Oxybutynin (USAN/INN)
Anturol (TN)
Oxytrol (TN)
Oxybutynin
[3]
6
6
,
13
,
53
💬
9. CHRM2
×
Disease ID
Name
6
Parkinson disease
13
Multiple sclerosis/Neuromyelitis optica
53
Sjogren syndrome
10
CHRM2
💬
10. CHRM2
×
Name
Full Name
CHRM2
cholinergic receptor muscarinic 2
[6]
Calcium signaling pathway
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K-Akt signaling pathway
,
Cholinergic synapse
,
Regulation of actin cytoskeleton
[6]
Calcium signaling pathway
,
cAMP signaling pathway
,
Neuroactive ligand-receptor interaction
,
PI3K
...
Pilocarpine
Pilocarpine
💬
10. CHRM2
×
Name
Other Names
Pilocarpine
Pilocarpine (JAN/USP)
Ocusert pilo-20 (TN)
Pilocarpine
[3]
6
6
,
53
,
299
💬
10. CHRM2
×
Disease ID
Name
6
Parkinson disease
53
Sjogren syndrome
299
Cystic fibrosis