DR info

Clinical trials : 95 / Drugs : 169 - (DrugBank : 61) / Drug target genes : 68 - Drug target pathways : 90

Drugs and their primary sponsors and trial info

/kg/hr TXA intravenous infusion till the last suture
   Peking Union Medical College Hospital
      2017   -   NCT03011866   -
0002-8971
   Middelfart Rygsektor
      2012   Phase 2   EUCTR2011-006152-36-DK   Denmark;
AK1320 MS
   Asahi Kasei Pharma Corporation
      2020   Phase 1   NCT04483297   Canada;
Acetaminophen
   Hospital for Special Surgery, New York
      2016   -   NCT02700451   United States;
Acetate
   Qilu Hospital of Shandong University
      2018   -   ChiCTR1800016968   China;
Acupuncture
   Jaseng Hospital of Korean Medicine
      2012   -   NCT02257723   Korea, Republic of;
   Jaseng Medical Foundation
      2019   -   NCT03879447   Korea, Republic of;
      2017   -   NCT02975011   Korea, Republic of;
Adjunctive analgesics
   Michael Schneider, DC, PhD
      2013   -   NCT01943435   United States;
Adjunctive anti-depressants
   Michael Schneider, DC, PhD
      2013   -   NCT01943435   United States;
AlloGen-LI
   University of Southern California
      2016   -   NCT02932020   United States;
Allograft
   Mesoblast, Ltd.
      2010   Phase 2   NCT01097486   United States;
Alprostadil
   Tokai University HospitalDepartment of Orthopaedic Surgery
      2010   -   JPRN-UMIN000005959   Japan;
Amino acids
   Wakayama Medical University
      2018   -   JPRN-UMIN000030881   Japan;
Amniotic Fluid Allograft
   University of Utah
      2021   Phase 1/Phase 2   NCT04537026   United States;
Apple Watch and App
   Stanford University
      2020   -   NCT04379921   United States;
Bee venom pharmacopuncture
   Jaseng Hospital of Korean Medicine
      2012   -   NCT02257723   Korea, Republic of;
   Jaseng Medical Foundation
      2019   -   NCT03879447   Korea, Republic of;
      2017   -   NCT02975011   Korea, Republic of;
Bilateral transforaminal epidural steroid injections
   Marshfield Clinic Research Foundation
      2013   -   NCT01995461   United States;
Bioactive Glass-Ceramic Spacer
   BioAlpha Inc.
      2010   -   NCT03532945   -
Bone Marrow Concentrate
   Stem Cures
      2018   Phase 2/Phase 3   NCT04559295   United States;
Botulinum toxin type A (Nabota®) injection into the gastrocnemius muscle
   Yonsei University
      2015   -   NCT02444351   Korea, Republic of;
Bupivacaine
Bupivacaine-Epinephrine -1:200,000 Injectable Solution plus clonidine
   John O'Toole
      2021   Phase 4   NCT05029726   United States;
Bupivacaïne HCl 0, / Sufentanil 50 µg flacon à 50 ml
Buprenorphine
   Seoul National University Hospital
      2015   Phase 4   NCT02416804   Korea, Republic of;
CONDUIT™ Interbody Platform composed of the EIT (Emerging Implant Technologies) Cellular Titanium®
   Farhan Karim
      2021   -   NCT05023733   United States;
Caudal Epidural Injection with Celestone
   Pain Management Center of Paducah
      2007   Phase 0   NCT00370799   United States;
Caudal Epidural Injection with DepoMedrol
   Pain Management Center of Paducah
      2007   Phase 0   NCT00370799   United States;
Caudal Epidural Injection with generic Celestone
   Pain Management Center of Paducah
      2007   Phase 0   NCT00370799   United States;
Celebrex 200Mg Capsule
   Seoul National University Bundang Hospital
      2018   Phase 4   NCT03584074   -
Celecoxib
   Department of Orthopedic Surgery Kobe University Graduate School of Medicine
      2012   -   JPRN-UMIN000007419   Japan;
   The First Affiliated Hospital of Chongqing Medical University
      2020   Phase 0   ChiCTR2000028775   China;
   University of Tsukuba, Course of life-style related disorders donated by JA Ibaraki Public Welfare Federation
      2011   Phase 3   JPRN-UMIN000004825   Japan;
   Wang Jing Hospital, Chinese Academy of Traditional Chinese Medicine
      2021   -   ChiCTR2100046515   China;
Cervical Orthosis (CO)
   Dr. Christopher Bailey
      2020   -   NCT04308122   Canada;
Chuna manipulation
   Jaseng Hospital of Korean Medicine
      2012   -   NCT02257723   Korea, Republic of;
   Jaseng Medical Foundation
      2017   -   NCT02975011   Korea, Republic of;
Chuna manual medicine
   Jaseng Medical Foundation
      2019   -   NCT03879447   Korea, Republic of;
Cilostazol
   Juntendo UniversityDepartment of Orthopaedic Surgery
      2011   -   JPRN-UMIN000006588   Japan;
Combination Product: Goldic serum
   Sutherland Medical Center
      2020   Phase 4   NCT04492774   Poland;
Control group
   Yonsei University
      2016   -   NCT02902380   Korea, Republic of;
Creatinine
   Nikaido Takuya
      2020   -   JPRN-jRCTs021200007   Japan;
Cupping
   Jaseng Medical Foundation
      2019   -   NCT03879447   Korea, Republic of;
      2017   -   NCT02975011   Korea, Republic of;
DEXMEDETOMIDINE HYDROCHLORIDE
   University of Turku
      2015   -   EUCTR2014-003252-31-FI   Finland;
Darvocet
   University of Rochester
      2008   Phase 4   NCT00652093   United States;
Decadron Phosphate, Injectable
   Hospital for Special Surgery, New York
      2017   Phase 4   NCT03245671   United States;
Deksmedetomidiini
   University of Turku
      2015   -   EUCTR2014-003252-31-FI   Finland;
Demineralized Bone Matrix
   OhioHealth
      2014   -   NCT02070484   United States;
DepoMedrol
   Europainclinics z.ú.
      2021   -   NCT02459392   Czech Republic;Czechia;
Depomedrol
   University of Southern California
      2016   -   NCT02932020   United States;
Dexamethasone sodium phosphate
   University of Utah
      2021   Phase 1/Phase 2   NCT04537026   United States;
Dexdor
   Kuopio University hospital
      2016   -   EUCTR2015-002694-37-FI   Finland;
   University of Turku
      2015   -   EUCTR2014-003252-31-FI   Finland;
Dexmedetomidine
   Vanderbilt University Medical Center
      2009   Phase 4   NCT00808665   United States;
Dexmedetomidine group
   New York University School of Medicine
      2010   -   NCT01377623   United States;
   Yonsei University
      2016   -   NCT02902380   Korea, Republic of;
Dexmedetomidine with ropivacaine
   Aristotle University Of Thessaloniki
      2020   Phase 4   NCT04391855   Greece;
Diphenhydramine
   University of Rochester
      2008   Phase 4   NCT00638443   United States;
ESKETAMINE HYDROCHLORIDE
   Helsinki Universiy Central Hospital
      2012   Phase 4   EUCTR2012-000747-26-FI   Finland;
Electroacupuncture
   Jaseng Medical Foundation
      2019   -   NCT03879447   Korea, Republic of;
      2017   -   NCT02975011   Korea, Republic of;
Epidural Steroid Injection
   Coastal Orthopedics & Sports Medicine
      2009   Phase 4   NCT00995371   United States;
   Hadassah Medical Organization
      2013   Phase 4   NCT01934868   Israel;
   Hospital for Special Surgery, New York
      2017   Phase 4   NCT03245671   United States;
   Vertos Medical, Inc.
      2014   -   NCT02093520   United States;
      2011   -   NCT01315145   United States;
Epidural injection
   Tel-Aviv Sourasky Medical Center
      2016   Phase 2/Phase 3   NCT02725723   -
Epidural local anesthetic injection
   University of Washington
      2011   Phase 4   NCT01238536   United States;
Epidural steroid (dexamethasone) injection
   Keimyung University Dongsan Medical Center
      2016   -   NCT02838615   -
Epidural steroid injection
   University of Washington
      2011   Phase 4   NCT01238536   United States;
Epidural steroid with local anesthetic injection
   University of Washington
      2011   Phase 4   NCT01238536   United States;
Epsilon-Aminocaproic Acid (EACA)
   National Heart, Lung, and Blood Institute (NHLBI)
      2000   -   NCT00320619   United States;
Erector spinae plane block (Group E)
   Medipol University
      2020   -   NCT04189341   Turkey;
Erythropoietin
   Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine
      2017   -   ChiCTR-INR-17012403   China;
Forsteo
   Department of Orthopaedics IKE
      2011   Phase 4   EUCTR2011-002917-12-SE   Sweden;
   Middelfart Rygsektor
      2012   Phase 2   EUCTR2011-006152-36-DK   Denmark;
Forteo
   Middelfart Rygsektor
      2012   Phase 2   EUCTR2011-006152-36-DK   Denmark;
Fusion
   Qilu Hospital of Shandong University
      2018   -   ChiCTR1800016968   China;
Heparin
   Seoul National University Bundang Hospital
      2012   -   NCT01522846   Korea, Republic of;
Herbal medicine
   Jaseng Hospital of Korean Medicine
      2012   -   NCT02257723   Korea, Republic of;
   Jaseng Medical Foundation
      2019   -   NCT03879447   Korea, Republic of;
      2017   -   NCT02975011   Korea, Republic of;
I-FACTOR
   Sygehus Lillebaelt
      2012   Phase 3   NCT01618435   Denmark;
Interbody cage (PEEK)
   Ohio State University
      2018   -   NCT03647501   United States;
Interbody cage (titanium)
   Ohio State University
      2018   -   NCT03647501   United States;
Kenalog Injectable Product
   Hospital for Special Surgery, New York
      2017   Phase 4   NCT03245671   United States;
Ketanest-S
   Helsinki Universiy Central Hospital
      2012   Phase 4   EUCTR2012-000747-26-FI   Finland;
   University of Turku
      2016   Phase 1;Phase 4   EUCTR2016-002887-14-FI   Finland;
Ketorolac
   Hospital for Special Surgery, New York
      2016   -   NCT02700451   United States;
Lidocaine Hydrochloride, Injectable
   Stanford University
      2021   Early Phase 1   NCT04992572   United States;
Limaprost
   Kansai LSS Forum
      2014   -   JPRN-UMIN000012918   Japan;
   University of Tsukuba, Course of life-style related disorders donated by JA Ibaraki Public Welfare Federation
      2011   Phase 3   JPRN-UMIN000004825   Japan;
   Yungjin Pharm. Co., Ltd.
      2013   Phase 4   NCT01888536   Korea, Republic of;
Liposomal bupivacaine
   Allina Health System
      2019   Phase 4   NCT03745040   United States;
   University of Colorado, Denver
      2021   Phase 2   NCT04066296   -
Lumbar Interbody Fusion with Autograft
   Mesoblast, Ltd.
      2009   Phase 2   NCT00996073   United States;
Lumbar Interbody Fusion with NeoFuse
   Mesoblast, Ltd.
      2009   Phase 2   NCT00996073   United States;
Lumbar epidural injection
   Michael Schneider, DC, PhD
      2013   -   NCT01943435   United States;
Lumbar interlaminar epidural steroid injection
   Emory University
      2014   -   NCT02103543   United States;
MILD Procedure
   Vertos Medical, Inc.
      2014   -   NCT02093520   United States;
MILD® (Minimally Invasive Lumbar Decompression)
   Coastal Orthopedics & Sports Medicine
      2009   Phase 4   NCT00995371   United States;
MRI
   University of Southern California
      2016   -   NCT02932020   United States;
Magnesium with ropivacaine
   Aristotle University Of Thessaloniki
      2020   Phase 4   NCT04391855   Greece;
Manual therapy
   Sutherland Medical Center
      2020   Phase 4   NCT04492774   Poland;
MasterGraft Granules
   Mesoblast, Ltd.
      2010   Phase 1/Phase 2   NCT01106417   Australia;
Mecobalamin
   Wang Jing Hospital, Chinese Academy of Traditional Chinese Medicine
      2021   -   ChiCTR2100046515   China;
Mirogabalin
   Nikaido Takuya
      2020   -   JPRN-jRCTs021200007   Japan;
Misoprostol
   Dallas VA Medical Center
      2019   -   NCT04611464   United States;
Modified-thoracolumbar interfascial plane block
   Medipol University
      2020   -   NCT04189341   Turkey;
Morphine PCA
   University Hospital, Basel, Switzerland
      2011   Phase 2/Phase 3   NCT01275547   Switzerland;
Multi-modal pain management [Acetaminophen + Gabapentin]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
Multi-modal pain management [Fentanyl]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
Multi-modal pain management [Intravenous Ketamine]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
Multi-modal pain management [Valium + Gabapentin]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
NS-304 Placebo
   Nippon Shinyaku Co., Ltd.
      2018   Phase 2   JPRN-JapicCTI-183866   Japan;
NSAIDs
   Michael Schneider, DC, PhD
      2013   -   NCT01943435   United States;
NeoFuse
   Mesoblast, Ltd.
      2010   Phase 2   NCT01097486   United States;
      2010   Phase 1/Phase 2   NCT01106417   Australia;
      2007   Phase 1/Phase 2   NCT00549913   United States;
Nicardipine
   Yonsei University
      2012   Phase 4   NCT02271191   -
Normal saline
   John O'Toole
      2021   Phase 4   NCT05029726   United States;
   Seoul National University Hospital
      2019   Phase 4   NCT04401735   Korea, Republic of;
NuCel
   OhioHealth
      2014   -   NCT02070484   United States;
OXYCODONE HYDROCHLORIDE
   University of Turku
      2015   -   EUCTR2014-003252-31-FI   Finland;
Oksikodoni
   University of Turku
      2015   -   EUCTR2014-003252-31-FI   Finland;
Opana
   University of Rochester
      2008   Phase 4   NCT00652093   United States;
Other intervention(s)
   Jaseng Medical Foundation
      2019   -   NCT03879447   Korea, Republic of;
Oxanest
   University of Turku
      2015   -   EUCTR2014-003252-31-FI   Finland;
Oxycodone Orion
   University of Turku
      2016   Phase 1;Phase 4   EUCTR2016-002887-14-FI   Finland;
Oxygen
   Yonsei University
      2016   -   NCT02625194   Korea, Republic of;
PCA
   Yonsei University
      2018   -   NCT03047044   Korea, Republic of;
PLF with NeoFuse
   Mesoblast, Ltd.
      2008   Phase 1/Phase 2   NCT00810212   United States;
PLF with autograft
   Mesoblast, Ltd.
      2008   Phase 1/Phase 2   NCT00810212   United States;
Percutaneous Lumbar Decompression
   Vertos Medical, Inc.
      2011   -   NCT01315145   United States;
Philips Intelivue MP70 monitor
   Yonsei University
      2016   -   NCT02826889   Korea, Republic of;
Pleth Variability Index (PVI)
   Yonsei University
      2016   -   NCT02826889   Korea, Republic of;
Polydeoxyribonucleotides
   Seoul National University Hospital
      2019   Phase 4   NCT04401735   Korea, Republic of;
Posterolateral spinal fusion with instrumentation
   Mesoblast, Ltd.
      2007   Phase 1/Phase 2   NCT00549913   United States;
Predinose oral
   Federal University of São Paulo
      2011   -   NCT01456377   Brazil;
Pregabalin
   Department of Orthopedic Surgery Kobe University Graduate School of Medicine
      2012   -   JPRN-UMIN000007419   Japan;
   Northwestern University
      2009   Phase 4   NCT00908375   United States;
   Seoul National University Bundang Hospital
      2018   Phase 4   NCT03584074   -
   The First Affiliated Hospital of Chongqing Medical University
      2020   Phase 0   ChiCTR2000028775   China;
   University of Rochester
      2008   Phase 4   NCT00638443   United States;
   Yungjin Pharm. Co., Ltd.
      2013   Phase 4   NCT01888536   Korea, Republic of;
Prolotherapy solution of dextrose
   Hadassah Medical Organization
      2013   Phase 4   NCT01934868   Israel;
Propofol Injection
   Stanford University
      2021   Early Phase 1   NCT04992572   United States;
Remifentanil
   Peking University Third Hospital
      2012   -   ChiCTR-TRC-13003639   China;
   Yonsei University
      2010   Phase 4   NCT01052324   Korea, Republic of;
RhPTH (1-34)
   Middelfart Rygsektor
      2012   Phase 2   EUCTR2011-006152-36-DK   Denmark;
Ropivacaine
   Higashi Ohmiya general hospital
      2010   -   JPRN-UMIN000005382   Japan;
Ropivacaine plus normal saline
   Aristotle University Of Thessaloniki
      2020   Phase 4   NCT04391855   Greece;
S-ketamine & midazolam
   University Hospital, Basel, Switzerland
      2011   Phase 2/Phase 3   NCT01275547   Switzerland;
Saline
   Vanderbilt University Medical Center
      2009   Phase 4   NCT00808665   United States;
Selective Nerve Root Block
   The Cleveland Clinic
      2018   Phase 4   NCT03801356   United States;
Selexipag
   Nippon Shinyaku Co., Ltd.
      2018   Phase 2   JPRN-JapicCTI-183866   Japan;
Standard analgesia use [Fentanyl]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
Standard analgesia use [Hydromorphone]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
Standard analgesia use [Oxygen]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
Standard analgesia use [Volatile Anesthesia]
   Johns Hopkins University
      2017   Early Phase 1   NCT03088306   United States;
Steroid injections
   Sutherland Medical Center
      2020   Phase 4   NCT04492774   Poland;
Sugar Pill
   Northwestern University
      2009   Phase 4   NCT00908375   United States;
Teicoplanin
   Bezmialem Vakif University
      2020   Phase 3   NCT04341831   -
Teriparatide
   Qilu Hospital of Shandong University
      2018   -   ChiCTR1800016968   China;
   University Hospital, Linkoeping
      2012   Phase 4   NCT02090244   Sweden;
Teriparatide [rDNA origin] contains recombinant human parathyroid hormone (1-34)
   Middelfart Rygsektor
      2012   Phase 2   EUCTR2011-006152-36-DK   Denmark;
Therm-AppTM TH, thermographic camera
   Tel-Aviv Sourasky Medical Center
      2016   Phase 2/Phase 3   NCT02725723   -
Titanium cage
   BioAlpha Inc.
      2010   -   NCT03532945   -
Tramadol
   Seoul National University Hospital
      2015   Phase 4   NCT02416804   Korea, Republic of;
Tramadol with ropivacaine
   Aristotle University Of Thessaloniki
      2020   Phase 4   NCT04391855   Greece;
Tranexamic Acid 100 MG/ML
   Hospital for Special Surgery, New York
      2018   Phase 3   NCT03553186   United States;
Transdermal fentanyl matrix, gabapentin
   Seoul National University Hospital
      2010   Phase 4   NCT01127100   Korea, Republic of;
Transforaminal Epidural Injection
   EJAVerheijen
      2020   -   NCT04540068   Netherlands;
Triamcinolone Acetonide and normal saline solution
   Navamindradhiraj University
      2016   -   NCT02939482   Thailand;
Tylenol
   Peking University Third Hospital
      2019   -   NCT04042948   China;
ViviGen Cellular Bone Matrix
   Ohio State University
      2019   Phase 4   NCT04007094   United States;
With U-VANCO (vancomycin hydrochloride)
   Taipei Veterans General Hospital, Taiwan
      2018   -   NCT03883022   Taiwan;
Without U-VANCO (vancomycin hydrochloride)
   Taipei Veterans General Hospital, Taiwan
      2018   -   NCT03883022   Taiwan;
Wound topically irrigated with 500mg TXA
   Peking Union Medical College Hospital
      2017   -   NCT03011866   -
Xylocaine
   Dept. of Orthopaedic Surgery, Graduate School of Medicine, Chiba University
      2014   -   JPRN-UMIN000015670   Japan;
marcaine
   University of Southern California
      2016   -   NCT02932020   United States;