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KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related

Adrenergic signaling in cardiomyocytes 💬

[5] ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬

Epinephrine 💬

Name	Other Names
Epinephrine	Epinephrine (USP/INN) Adrenaline (JP18) Adrenalin (TN) Auvi-q (TN) Epipen (TN) ADRENALIN(R) CERTA DOSE EPINEPHRINE CONVENIENCE KIT EPINEPHRINE CONVENIENCE KIT EPINEPHRINE PROFESSIONAL EPINEPHRINE PROFESSIONAL EMS EPINEPHRINESNAP-EMS EPINEPHRINESNAP-V SYMJEPI

Epinephrine

[3] 46, 70, 96 💬

Adrenergic signaling in cardiomyocytes 💬

[4] CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬

Name	Full Name
CACNA1C	calcium voltage-gated channel subunit alpha1 C
CACNA1D	calcium voltage-gated channel subunit alpha1 D
CACNA1F	calcium voltage-gated channel subunit alpha1 F
CACNA1S	calcium voltage-gated channel subunit alpha1 S

Nicardipine 💬

Nicardipine

[2] 70, 86 💬

Adrenergic signaling in cardiomyocytes 💬

[2] CACNA2D1, CACNA2D2 💬

Mirogabalin 💬

Mirogabalin

[1] 70 💬

Adrenergic signaling in cardiomyocytes 💬

[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬

Name	Full Name
CACNA2D1	calcium voltage-gated channel auxiliary subunit alpha2delta 1
CACNA2D2	calcium voltage-gated channel auxiliary subunit alpha2delta 2
CACNA2D3	calcium voltage-gated channel auxiliary subunit alpha2delta 3
CACNA2D4	calcium voltage-gated channel auxiliary subunit alpha2delta 4

Gabapentin 💬

Gabapentin

[5] 6 , 13, 19, 70, 298 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
19	Lysosomal storage disease;Lysosomal disease;
70	Spinal stenosis;Extensive spinal canal stenosis;
298	Hereditary pancreatitis;Chronic pancreatitis;

Adrenergic signaling in cardiomyocytes 💬

[4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬

Name	Full Name
CACNA2D1	calcium voltage-gated channel auxiliary subunit alpha2delta 1
CACNA2D2	calcium voltage-gated channel auxiliary subunit alpha2delta 2
CACNA2D3	calcium voltage-gated channel auxiliary subunit alpha2delta 3
CACNA2D4	calcium voltage-gated channel auxiliary subunit alpha2delta 4

Pregabalin 💬

Pregabalin

[5] 13, 36, 46, 70, 298 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
70	Spinal stenosis;Extensive spinal canal stenosis;
298	Hereditary pancreatitis;Chronic pancreatitis;

Adrenergic signaling in cardiomyocytes 💬

[1] SCN5A 💬

Bupivacaine 💬

Bupivacaine

[8] 46, 51, 53, 70, 96, 168, 226, 298 💬

Disease ID	Name
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
53	Sjogren syndrome;Sjögren syndrome;Syndrome Sjogren's;SS;Autoimmune exocrinopathy;
70	Spinal stenosis;Extensive spinal canal stenosis;
96	Crohn disease;Terminal ileitis;
168	Ehlers-Danlos syndrome;EDS;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
298	Hereditary pancreatitis;Chronic pancreatitis;

Adrenergic signaling in cardiomyocytes 💬

[1] SCN5A 💬

Lidocaine 💬

Lidocaine

[13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
22	Moyamoya disease;Occlusive disease in circle of Willis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
84	Sarcoidosis;
86	Pulmonary arterial hypertension;PAH;
107	Juvenile idiopathic arthritis;JIA;
168	Ehlers-Danlos syndrome;EDS;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
256	Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;

Adrenergic signaling in cardiomyocytes 💬

[1] SCN5A 💬

Lidocaine hydrochloride monohydrate 💬

Name	Other Names
Lidocaine hydrochloride monohydrate	Lidocaine hydrochloride monohydrate Lidocaine (TN) Zingo (TN) 1% LIDOCAINE HCI 2% LIDOCAINE HCI LIDENZAL 1% LIDENZAL 2% LIDOCAINE HCI LIDOCAINE HCL LIDOCAINE HYDROCHLORIDE NA PRELIDOPINE PRE-OPERATIVE SYSTEM

Lidocaine

[13] 6 , 13, 22, 34, 46, 51, 70, 84, 86, 107, 168, 226, 256 💬

Disease ID	Name
6	Parkinson disease;Disease Parkinson's;
13	Multiple sclerosis/Neuromyelitis optica;
22	Moyamoya disease;Occlusive disease in circle of Willis;
34	Neurofibromatosis;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
51	Scleroderma;Systemic sclerosis;SSc;
70	Spinal stenosis;Extensive spinal canal stenosis;
84	Sarcoidosis;
86	Pulmonary arterial hypertension;PAH;
107	Juvenile idiopathic arthritis;JIA;
168	Ehlers-Danlos syndrome;EDS;
226	Interstitial cystitis with Hunners ulcer;Interstitial cystitis;
256	Muscle glycogenosis;Muscular glycogenosis;Muscle glycogen storage disease;Muscular glycogen storage disease;

Adrenergic signaling in cardiomyocytes 💬

[1] SCN5A 💬

Ropivacaine 💬

Ropivacaine

[4] 22, 36, 46, 70 💬

Disease ID	Name
22	Moyamoya disease;Occlusive disease in circle of Willis;
36	Epidermolysis bullosa;
46	Malignant rheumatoid arthritis;MRA;Rheumatoid vasculitis;RV;Rheumatoid arthritis;RA;
70	Spinal stenosis;Extensive spinal canal stenosis;

Alcoholism 💬

[1] DRD2 💬

Sulpiride 💬

Sulpiride

[2] 6 , 70 💬

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