89. Lymphangioleiomyomatosis Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 38 / Drugs : 38 - (DrugBank : 15) / Drug target genes : 18 - Drug target pathways : 118
Drugs and their primary sponsors and trial info
68Ga-NEB
Peking Union Medical College Hospital
2019 Phase 1 NCT04273334 China;
Afinitor
Novartis Pharma Service AG
2010 - EUCTR2010-019825-32-FR France;Italy;
Novartis Pharma Services AG
- Phase 3 EUCTR2008-002113-48-DE Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Afinitor 5mg Tablets
Novartis Pharma Services AG
2009 Phase 3 EUCTR2008-002113-48-GB Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Albuterol inhaler
National Heart, Lung, and Blood Institute (NHLBI)
2013 Phase 1/Phase 2 NCT01799538 United States;
Albuterol nebulizer
National Heart, Lung, and Blood Institute (NHLBI)
2013 Phase 1/Phase 2 NCT01799538 United States;
Bevacizumab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Celecoxib
Brigham and Women's Hospital
2016 Phase 2 NCT02484664 United States;
Cetuximab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Doxycycline
University of Nottingham
2009 Phase 4 NCT00989742 United Kingdom;
Doxycycline 100 mg Capsules
University of Nottingham
2008 - EUCTR2007-003745-32-GB United Kingdom;
Everolimus
NOVARTIS FARMA
2010 - EUCTR2010-019825-32-IT France;Italy;
2009 - EUCTR2008-002113-48-IT France;Germany;Italy;Netherlands;Spain;United Kingdom;
Novartis Pharma Service AG
2010 - EUCTR2010-019825-32-FR France;Italy;
Novartis Pharma Services AG
2009 Phase 3 EUCTR2008-002113-48-GB Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Novartis Pharmaceuticals
2010 Phase 2 NCT01059318 France;Germany;Italy;United States;
University of Cincinnati
2015 - NCT02432560 United States;
Everolimus (RAD001)
Children's Hospital Medical Center, Cincinnati
2008 Phase 1/Phase 2 NCT00792766 United States;
Novartis Pharmaceuticals
2009 Phase 3 NCT00790400 Canada;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United Kingdom;United States;
Everolimus Oral Product
University of Pennsylvania
2014 Phase 1/Phase 2 NCT02061397 United States;
Glutamine
Vanderbilt University Medical Center
2019 Phase 1 NCT04388371 United States;
Imatinib Mesylate 400Mg Capsule
Medical University of South Carolina
2018 Phase 1/Phase 2 NCT03131999 United States;
Letrozole
University of Cincinnati
2011 Phase 2 NCT01353209 United States;
Nintedanib
IRCCS Multimedica
2016 Phase 2 NCT03062943 Italy;
Octreotide
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00005906 United States;
Ofev
MULTIMEDICA S.P.A.
2016 Phase 3 EUCTR2015-004919-20-IT Italy;
PFT
National Heart, Lung, and Blood Institute (NHLBI)
2013 Phase 1/Phase 2 NCT01799538 United States;
RAD001
Children's Hospital Medical Center, Cincinnati
2005 Phase 1/Phase 2 NCT00457964 United States;
NOVARTIS FARMA
2009 - EUCTR2008-002113-48-IT France;Germany;Italy;Netherlands;Spain;United Kingdom;
Novartis Pharma Service AG
2010 - EUCTR2010-019825-32-FR France;Italy;
Novartis Pharma Services AG
2010 - EUCTR2008-002113-48-NL France;Germany;Italy;Netherlands;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-002113-48-GB Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
2009 Phase 3 EUCTR2008-002113-48-FR France;Germany;Italy;Netherlands;Spain;United Kingdom;
- Phase 3 EUCTR2008-002113-48-DE Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Rapamycin, sirolimus
Children's Hospital Medical Center, Cincinnati
2002 Phase 2 NCT00457808 United States;
Resveratrol
University of Cincinnati
2018 Phase 2 NCT03253913 United States;
Saracatinib
Baylor College of Medicine
2016 Phase 2 NCT02737202 United States;
Tony Eissa
2014 Phase 1 NCT02116712 United States;
Simvastatin
University of Pennsylvania
2014 Phase 1/Phase 2 NCT02061397 United States;
Sirolimus
Cardiff University
2005 Phase 2 NCT00490789 United Kingdom;
Frank McCormack, M.D., University of Cincinnati Medical Center Director, Division of Pulmonary and Critical Care Medicine
2008 Phase 3 JPRN-JMA-IIA00011 Japan, United States, Canada;
Kobe University Graduate School of Medicine
2012 - JPRN-UMIN000007387 Japan;
Koh Nakata, MD, Ph.D
2011 Phase 2 JPRN-JMA-IIA00037 Japan;
National Hospital Organization Kinki-chuo Chest Medical Center
2015 - JPRN-UMIN000016677 Japan;
Office of Rare Diseases (ORD)
2006 Phase 3 NCT00414648 Canada;Japan;United States;
University of Cincinnati
2018 Phase 3 NCT03150914 United States;
2018 Phase 2 NCT03253913 United States;
2015 - NCT02432560 United States;
Sirolimus Oral Product
University of Pennsylvania
2014 Phase 1/Phase 2 NCT02061397 United States;
Sirolimus and Hydroxychloroquine
Brigham and Women's Hospital
2012 Phase 1 NCT01687179 United States;
Srolimus
Koh Nakata, MD, PhD
2012 Phase 2 JPRN-JMA-IIA00096 Japan;
Temsirolimus
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Peking Union Medical College Hospital
2019 Phase 1 NCT04273334 China;
Afinitor
Novartis Pharma Service AG
2010 - EUCTR2010-019825-32-FR France;Italy;
Novartis Pharma Services AG
- Phase 3 EUCTR2008-002113-48-DE Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Afinitor 5mg Tablets
Novartis Pharma Services AG
2009 Phase 3 EUCTR2008-002113-48-GB Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Albuterol inhaler
National Heart, Lung, and Blood Institute (NHLBI)
2013 Phase 1/Phase 2 NCT01799538 United States;
Albuterol nebulizer
National Heart, Lung, and Blood Institute (NHLBI)
2013 Phase 1/Phase 2 NCT01799538 United States;
Bevacizumab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Celecoxib
Brigham and Women's Hospital
2016 Phase 2 NCT02484664 United States;
Cetuximab
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;
Doxycycline
University of Nottingham
2009 Phase 4 NCT00989742 United Kingdom;
Doxycycline 100 mg Capsules
University of Nottingham
2008 - EUCTR2007-003745-32-GB United Kingdom;
Everolimus
NOVARTIS FARMA
2010 - EUCTR2010-019825-32-IT France;Italy;
2009 - EUCTR2008-002113-48-IT France;Germany;Italy;Netherlands;Spain;United Kingdom;
Novartis Pharma Service AG
2010 - EUCTR2010-019825-32-FR France;Italy;
Novartis Pharma Services AG
2009 Phase 3 EUCTR2008-002113-48-GB Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Novartis Pharmaceuticals
2010 Phase 2 NCT01059318 France;Germany;Italy;United States;
University of Cincinnati
2015 - NCT02432560 United States;
Everolimus (RAD001)
Children's Hospital Medical Center, Cincinnati
2008 Phase 1/Phase 2 NCT00792766 United States;
Novartis Pharmaceuticals
2009 Phase 3 NCT00790400 Canada;France;Germany;Italy;Japan;Netherlands;Poland;Russian Federation;Spain;United Kingdom;United States;
Everolimus Oral Product
University of Pennsylvania
2014 Phase 1/Phase 2 NCT02061397 United States;
Glutamine
Vanderbilt University Medical Center
2019 Phase 1 NCT04388371 United States;
Imatinib Mesylate 400Mg Capsule
Medical University of South Carolina
2018 Phase 1/Phase 2 NCT03131999 United States;
Letrozole
University of Cincinnati
2011 Phase 2 NCT01353209 United States;
Nintedanib
IRCCS Multimedica
2016 Phase 2 NCT03062943 Italy;
Octreotide
National Heart, Lung, and Blood Institute (NHLBI)
2000 Phase 2 NCT00005906 United States;
Ofev
MULTIMEDICA S.P.A.
2016 Phase 3 EUCTR2015-004919-20-IT Italy;
PFT
National Heart, Lung, and Blood Institute (NHLBI)
2013 Phase 1/Phase 2 NCT01799538 United States;
RAD001
Children's Hospital Medical Center, Cincinnati
2005 Phase 1/Phase 2 NCT00457964 United States;
NOVARTIS FARMA
2009 - EUCTR2008-002113-48-IT France;Germany;Italy;Netherlands;Spain;United Kingdom;
Novartis Pharma Service AG
2010 - EUCTR2010-019825-32-FR France;Italy;
Novartis Pharma Services AG
2010 - EUCTR2008-002113-48-NL France;Germany;Italy;Netherlands;Spain;United Kingdom;
2009 Phase 3 EUCTR2008-002113-48-GB Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
2009 Phase 3 EUCTR2008-002113-48-FR France;Germany;Italy;Netherlands;Spain;United Kingdom;
- Phase 3 EUCTR2008-002113-48-DE Canada;France;Germany;Italy;Japan;Netherlands;Russian Federation;Spain;United Kingdom;United States;
Rapamycin, sirolimus
Children's Hospital Medical Center, Cincinnati
2002 Phase 2 NCT00457808 United States;
Resveratrol
University of Cincinnati
2018 Phase 2 NCT03253913 United States;
Saracatinib
Baylor College of Medicine
2016 Phase 2 NCT02737202 United States;
Tony Eissa
2014 Phase 1 NCT02116712 United States;
Simvastatin
University of Pennsylvania
2014 Phase 1/Phase 2 NCT02061397 United States;
Sirolimus
Cardiff University
2005 Phase 2 NCT00490789 United Kingdom;
Frank McCormack, M.D., University of Cincinnati Medical Center Director, Division of Pulmonary and Critical Care Medicine
2008 Phase 3 JPRN-JMA-IIA00011 Japan, United States, Canada;
Kobe University Graduate School of Medicine
2012 - JPRN-UMIN000007387 Japan;
Koh Nakata, MD, Ph.D
2011 Phase 2 JPRN-JMA-IIA00037 Japan;
National Hospital Organization Kinki-chuo Chest Medical Center
2015 - JPRN-UMIN000016677 Japan;
Office of Rare Diseases (ORD)
2006 Phase 3 NCT00414648 Canada;Japan;United States;
University of Cincinnati
2018 Phase 3 NCT03150914 United States;
2018 Phase 2 NCT03253913 United States;
2015 - NCT02432560 United States;
Sirolimus Oral Product
University of Pennsylvania
2014 Phase 1/Phase 2 NCT02061397 United States;
Sirolimus and Hydroxychloroquine
Brigham and Women's Hospital
2012 Phase 1 NCT01687179 United States;
Srolimus
Koh Nakata, MD, PhD
2012 Phase 2 JPRN-JMA-IIA00096 Japan;
Temsirolimus
M.D. Anderson Cancer Center
2012 Phase 1 NCT01552434 United States;