Reduced Intensity Conditioning

( DrugBank: - / KEGG DRUG: - )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
19	ライソゾーム病	1

告示番号	疾患名（ページ内リンク）	臨床試験数
65	原発性免疫不全症候群	8

19. ライソゾーム病

臨床試験数 : 899 / 薬物数 : 684 - (DrugBank : 99) / 標的遺伝子数 : 51 - 標的パスウェイ数 : 182

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00744692 (ClinicalTrials.gov)	October 2008	28/8/2008	Reduced Intensity Conditioningfor Umbilical Cord Blood Transplant in Pediatric Patients With Non-Mal ...	A Pilot Study of Reduced Intensity Conditioningin Pediatric Patients <21 Years of Age With Non-Malig ...	Non Malignant Disorders;Immunodeficiencies;Congenital Marrow Failures;Hemoglobinopathies;Inborn Erro ...	Biological: Unrelated Umbilical Cord Blood Transplant;Drug: Reduced Intensity Conditioning	Duke University	NULL	Completed	N/A	21 Years	All	22	Phase 1	United States

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65. 原発性免疫不全症候群

臨床試験数 : 500 / 薬物数 : 614 - (DrugBank : 119) / 標的遺伝子数 : 92 - 標的パスウェイ数 : 217

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Showing 1 to 8 of 8 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04528355 (ClinicalTrials.gov)	August 20, 2020	18/8/2020	Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RI ...	A Prospective Outcomes Study of Pediatric and Adult Patients With Non-Malignant Disorders Undergoing ...	Primary Immunodeficiency (PID);Congenital Bone Marrow Failure Syndromes;Inherited Metabolic Disorder ...	Drug: data collection	Paul Szabolcs	NULL	Recruiting	2 Months	60 Years	All	50		United States
2	NCT03663933 (ClinicalTrials.gov)	September 4, 2018	7/9/2018	Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregula ...	Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferatio ...	Lymphoproliferative Disorders;Autoimmune Lymphoproliferative;Primary T-cell Immunodeficiency Disorde ...	Drug: Immunosuppression Only Conditioning;Drug: Reduced Intensity Conditioning;Drug: GVHD Prophylaxi ...	National Cancer Institute (NCI)	NULL	Recruiting	4 Years	N/A	All	177	Phase 2	United States
3	JPRN-jRCTs031180398 (jRCTs031180398)	30/05/2018	20/03/2019	A phase II study of RIC-SCT for CGD	Reduced intensity conditioningallogeneic stem cell transplantation with dose-adjusted busulfan and a ...	Chronic granulomatous disease Primary immunodeficiency;D006105	Conditioningregimen with targeted-busulfan and fludarabin Total body irradiation (3Gy) at day -1 Ste ...	Sakaguchi Hirotoshi	NULL	Recruiting	Not applicable	< 25age old	Both	22	Phase 2	None (Japan only);Japan
4	JPRN-UMIN000030647	2017/12/30	31/12/2017	Reduced intensity conditioningallogeneic stem cell transplantation with dose-adjusted busulfan and a ...	Reduced intensity conditioningallogeneic stem cell transplantation with dose-adjusted busulfan and a ...	Chronic granulomatous disease	Conditioningregimen with targeted-busulfan and fludarabin Total body irradiation (3Gy) at day -1 Ste ...	National Center for Child Health and Development	NULL	Recruiting	Not applicable	25years-old	Male and Female	22	Phase 2	Japan
5	JPRN-UMIN000022688	2016/06/10	13/06/2016	A pilot study of reduced intensity conditioningallogeneic stem cell transplantation with dose-adjust ...	A pilot study of reduced intensity conditioningallogeneic stem cell transplantation with dose-adjust ...	Chronic granulomatous disease	Conditioningregimen with targeted-busulfan and fludarabin Total body irradiation (3Gy) at day -1 Stem ...	National Center for Child Health and Development	NULL	Complete: follow-up complete	Not applicable	25years-old	Male and Female	9	Not selected	Japan
6	NCT02579967 (ClinicalTrials.gov)	November 19, 2015	16/10/2015	Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies	Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies	Primary T-cell Immunodeficiency Disorders;Common Variable Immunodeficiency;Immune System Diseases;Au ...	Drug: Immunosuppression Only Conditioning-Closed with amendment L;Drug: Reduced Intensity Conditioni ...	National Cancer Institute (NCI)	NULL	Recruiting	4 Years	75 Years	All	224	Phase 2	United States
7	NCT01962415 (ClinicalTrials.gov)	February 4, 2014	10/10/2013	Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT	A Phase II Study of Reduced Intensity Conditioningin Pediatric Patients and Young Adults =55 Years o ...	Primary Immunodeficiency (PID);Congenital Bone Marrow Failure Syndromes;Inherited Metabolic Disorder ...	Drug: Hydroxyurea;Drug: Alemtuzumab;Drug: Fludarabine;Drug: Melphalan;Drug: Thiotepa	Paul Szabolcs	NULL	Recruiting	2 Months	55 Years	All	100	Phase 2	United States
8	NCT01998633 (ClinicalTrials.gov)	December 2013	29/10/2013	Reduced Intensity Conditioningfor Hemophagocytic Syndromes or Selected Primary Immune Deficiencies ( ...	Reduced-Intensity Conditioningfor Children and Adults With Hemophagocytic Syndromes or Selected Prim ...	Hemophagocytic Lymphohistiocytosis;Chronic Active Epstein-Barr Virus Infection;Chronic Granulomatous ...	Biological: Hematopoietic Stem Cell Transplant	Medical College of Wisconsin	National Heart, Lung, and Blood Institute (NHLBI);Blood and Marrow Transplant Clinical Trials Networ ...	Completed	4 Months	45 Years	All	47	Phase 2	United States;Canada

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