Pomalidomide and Dexamethasone

( DrugBank: Pomalidomide / KEGG DRUG: Pomalidomide )

1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
28	全身性アミロイドーシス	8

28. 全身性アミロイドーシス

臨床試験数 : 267 / 薬物数 : 241 - (DrugBank : 77) / 標的遺伝子数 : 68 - 標的パスウェイ数 : 180

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Showing 1 to 8 of 8 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05451771 (ClinicalTrials.gov)	October 26, 2022	6/7/2022	Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis	An Open-label Phase I/II Trial of Venetoclax-Dexamethasonein Relapsed and/or Refractory t(11;14) Sys ...	AL Amyloidosis	Drug: Venetoclax Oral Tablet, 200 mg;Device: FISH assay;Drug: Venetoclax Oral Tablet, 400 mg;Drug: D ...	Rajshekhar Chakraborty, MD	Genentech, Inc.	Recruiting	18 Years	N/A	All	53	Phase 1/Phase 2	United States
2	NCT05066607 (ClinicalTrials.gov)	February 11, 2022	24/8/2021	Isatuximab Plus Pomalidomide and DexamethasoneAssociation for Patients With AL Amyloidosis Not in VG ...	A Phase 2, Open Label, Multicenter, Single-stage Study to Evaluate the Efficacy of Isatuximab Plus P ...	AL Amyloidosis	Drug: Isatuximab	Intergroupe Francophone du Myelome	Sanofi;Bristol-Myers Squibb	Recruiting	18 Years	N/A	All	46	Phase 2	France
3	NCT04270175 (ClinicalTrials.gov)	April 14, 2021	12/2/2020	Daratumumab, Pomalidomide, and Dexamethasone(DPd) in Relapsed/Refractory Light Chain Amyloidosis Pat ...	Daratumumab, Pomalidomide, and Dexamethasone(DPd) in Relapsed/Refractory Light Chain Amyloidosis Pat ...	Amyloid;AL Amyloidosis;Refractory AL Amyloidosis	Drug: Daratumumab;Drug: Pomalidomide;Drug: Dexamethasone	Weill Medical College of Cornell University	Janssen Scientific Affairs, LLC	Recruiting	18 Years	N/A	All	21	Phase 2	United States
4	NCT01807286 (ClinicalTrials.gov)	January 2014	6/3/2013	Pomalidomide With Melphalan and Dexamethasone for Untreated Systemic AL Amyloidosis	A Phase I/II Clinical Trial of PomalidomideWith Melphalan and Dexamethasonein Patients With Newly Di ...	Myeloma	Drug: Pomalidomide;Drug: Melphalan;Drug: Dexamethasone;Behavioral: Questionnaires	M.D. Anderson Cancer Center	Celgene	Terminated	18 Years	N/A	Both	3	Phase 1	United States
5	NCT01728259 (ClinicalTrials.gov)	March 2013	13/11/2012	First-line Pomalidomide, Bortezomib, and Dexamethasone For AL Amyloidosis or LCDD	Phase I Study of Pomalidomide, Bortezomib, and Dexamethasone(PVD) as First-Line Treatment of AL Amyl ...	Light Chain Deposition Disease;Primary Systemic Amyloidosis	Drug: pomalidomide;Drug: bortezomib;Drug: dexamethasone;Other: Laboratory Biomarker Analysis	Barbara Ann Karmanos Cancer Institute	National Cancer Institute (NCI)	Active, not recruiting	18 Years	N/A	All	36	Phase 1	United States;Canada;New Zealand
6	NCT01570387 (ClinicalTrials.gov)	June 2012	27/2/2012	A Phase I/II Trial of Pomalidomide and Dexamethasonein Subjects With Previously-Treated AL Amyloidos ...	A Phase I/II Trial of Pomalidomide and Dexamethasonein Subjects With Previously-Treated AL Amyloidos ...	AL Amyloidosis	Drug: Pomalidomide;Drug: Dexamethasone	Boston Medical Center	Celgene Corporation	Completed	18 Years	N/A	All	27	Phase 1/Phase 2	United States
7	EUCTR2011-001787-22-IT (EUCTR)	02/05/2012	12/01/2012	Treatment with pomalidomide and dexamethasone for previously treated patients with AL amyloidosis.	An open-label, phase II study of Pomalidomide and Dexamethasone(PDex) for previously treated patient ...	Previously treated AL amyloidosis MedDRA version: 14.1;Level: PT;Classification code 10002022;Term: ...	Product Name: pomalidomide Product Code: CC-4047 INN or Proposed INN: Pomalidomide INN or Proposed INN: ...	OSPEDALE POLICLINICO S. MATTEO	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes		Phase 2	Italy
8	NCT01510613 (ClinicalTrials.gov)	February 2012	11/1/2012	Pomalidomide and Dexamethasone (PDex) in AL Amyloidosis	An Open-label, Phase II Study of Pomalidomide and Dexamethasone(PDex) for Previously Treated Patient ...	Primary Amyloidosis of Light Chain Type	Drug: Pomalidomide and Dexamethasone	IRCCS Policlinico S. Matteo	NULL	Completed	18 Years	N/A	All	28	Phase 2	Italy

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