Methotrexate Placebo

( DrugBank: Methotrexate / KEGG DRUG: Methotrexate )

1 disease

告示番号	疾患名（ページ内リンク）	臨床試験数
46	悪性関節リウマチ	1158

46. 悪性関節リウマチ

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05604885 (ClinicalTrials.gov)	November 30, 2022	31/10/2022	A Dose-range Study of the Safety and Efficacy of Treatment in Adult Rheumatoid Arthritis Patients Wi ...	A Two-part, Randomized, Double-blind, Multi-center, Placebo-controlled Study of the Dose-range, Safe ...	Rheumatoid Arthritis	Drug: AP1189, 60 mg;Drug: AP1189, 80 mg;Drug: AP1189, 100 mg;Drug: Placebo	SynAct Pharma Aps	NBCD A/S	Recruiting	18 Years	85 Years	All	420	Phase 2	Moldova, Republic of
2	NCT05594680 (ClinicalTrials.gov)	November 1, 2022	18/10/2022	Cilostazol and Methotrexate in Rheumatoid Arthritis	The Phosphodiesterase 3 Inhibitor Cilostazol as Adjunct to Methotrexatein Patients With Rheumatoid A ...	Rheumatoid Arthritis	Drug: Cilostazol;Drug: Methotrexate;Drug: Placebo	Tanta University	NULL	Not yet recruiting	18 Years	60 Years	All	70	Phase 3	NULL
3	NCT05533372 (ClinicalTrials.gov)	October 10, 2022	5/9/2022	MAD Study of IA-14069	Randomized, Double-Blind, Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, ...	Healthy;Rheumatoid Arthritis	Drug: IA-14069;Drug: Placebo;Drug: Methotrexate	ILAb Co., Ltd.	NULL	Recruiting	18 Years	70 Years	All	75	Phase 1	United States
4	NCT05460832 (ClinicalTrials.gov)	August 29, 2022	12/7/2022	Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA	A Randomised, Double-Blind, Placebo-Controlled, Dose-Ranging Phase 2b Study to Investigate the Effic ...	Rheumatoid Arthritis	Drug: MBS2320 5 mg;Drug: MBS2320 20 mg;Drug: MBS2320 40 mg;Drug: Placebo	Modern Biosciences Ltd	NULL	Recruiting	18 Years	75 Years	All	224	Phase 2	Bosnia and Herzegovina;Bulgaria;Chile;Czechia;Guatemala;Mexico;Poland;Serbia
5	NCT05363891 (ClinicalTrials.gov)	June 15, 2022	2/5/2022	Natrunix or Placebo in Combination With Methotrexate in Rheumatoid Arthritis	Phase II, Double-blind, Placebo-Controlled, Randomized Trial Examining Natrunix in Combination With ...	Rheumatoid Arthritis	Drug: Natrunix;Drug: Placebo	XBiotech, Inc.	NULL	Not yet recruiting	18 Years	N/A	All	150	Phase 2	NULL
6	NCT05363917 (ClinicalTrials.gov)	June 15, 2022	2/5/2022	Natrunix Versus Methotrexate in Rheumatoid Arthritis	Phase II Double-Blinded, Placebo-Controlled Randomized Study Examining the Safety and Efficacy of Na ...	Rheumatoid Arthritis	Drug: Natrunix with MTX placebo (+folate);Drug: Natrunix placebo with MTX (+folate)	XBiotech, Inc.	NULL	Not yet recruiting	18 Years	N/A	All	150	Phase 2	NULL
7	NCT05374785 (ClinicalTrials.gov)	May 1, 2022	4/5/2022	Efficacy and Safety Study Comparing CPL409116 to Placeboin Participants With Active Rheumatoid Arthr ...	A 12-week, Phase II, Multicentre, Randomised, Double Blind, Efficacy and Safety Study Comparing CPL4 ...	Rheumatoid Arthritis	Drug: CPL409116;Other: Placebo	Celon Pharma SA	National Center for Research and Development, Poland	Recruiting	18 Years	75 Years	All	100	Phase 2	Poland
8	NCT05380934 (ClinicalTrials.gov)	May 2022	16/5/2022	A Clinical Trial of Safety and Tolerance of TQH3821 Tablets in Adult Healthy Subjects	A Randomized, Double-blind, Placebo-controlled Phase I Clinical Trial of TQH3821 in Adult Healthy Su ...	Rheumatoid Arthritis	Drug: TQH3821 tablets;Drug: TQH3821 tablets (Placebo);Drug: Methotrexate tablets	Chia Tai Tianqing Pharmaceutical Group Co., Ltd.	NULL	Recruiting	18 Years	55 Years	All	62	Phase 1	China
9	NCT05166304 (ClinicalTrials.gov)	April 2022	8/12/2021	Rebamipide in Patients With Active Rheumatoid Arthritis	Rebamipide as an Adjunct to Methotrexate in Patients With Active Rheumatoid Arthritis	Rheumatoid Arthritis	Drug: Rebamipide;Drug: Placebo	October 6 University	NULL	Not yet recruiting	18 Years	60 Years	All	100	Phase 1/Phase 2	NULL
10	NCT05245448 (ClinicalTrials.gov)	February 22, 2022	22/1/2022	Tetrandrine in the Treatment of Rheumatoid Arthritis	Comparing the Efficacy of Tetrandrine Combined With Methotrexateand MethotrexateAlone in the Treatme ...	Rheumatoid Arthritis	Drug: Tetrandrine;Drug: Placebo	Peking University People's Hospital	NULL	Not yet recruiting	18 Years	65 Years	All	240	N/A	China

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