AMANTADINE HYDROCHLORIDE

( DrugBank: Amantadine / KEGG DRUG: Amantadine )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
6	パーキンソン病	13

告示番号	疾患名（ページ内リンク）	臨床試験数
13	多発性硬化症／視神経脊髄炎	1

6. パーキンソン病

臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2014-003738-24-AT (EUCTR)	26/06/2015	01/04/2015	A clinical trial to see if ADS-5102 is safe and effective in people with drug induced abnormal movem ...	ADS-5102 (Amantadine HCl) Extended Release Efficacy and Safety Study in Parkinson's Disease Patients ...	Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease MedDRA version: 17.1;L ...	Product Name: Amantadine HCl Extended Release Capsule Product Code: ADS-5102 INN or Proposed INN: Aman ...	Adamas Pharmaceuticals, Inc.	NULL	Not Recruiting	Female: yes Male: yes	72	Phase 3	Germany;Spain;Austria;United States
2	EUCTR2014-003739-20-AT (EUCTR)	19/06/2015	01/04/2015	A clinical trial to see if ADS-5102 is safe in people with drug induced abnormal movements in Parkin ...	Open-Label Safety Study of ADS-5102 (Amantadine HCl) Extended Release Capsules for the Treatment of ...	Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease MedDRA version: 18.1;L ...	Product Name: Amantadine HCl Extended Release Capsule Product Code: ADS-5102 INN or Proposed INN: Aman ...	Adamas Pharmaceuticals, Inc.	NULL	Not Recruiting	Female: yes Male: yes	250	Phase 3	United States;Spain;Austria;Germany
3	EUCTR2014-003738-24-DE (EUCTR)	23/04/2015	21/01/2015	A clinical trial to see if ADS-5102 is safe and effective in people with drug induced abnormal movem ...	ADS-5102 (Amantadine HCl) Extended Release Efficacy and Safety Study in Parkinson's Disease Patients ...	Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease MedDRA version: 18.0;L ...	Product Name: Amantadine HCl Extended Release Capsule Product Code: ADS-5102 INN or Proposed INN: Aman ...	Adamas Pharmaceuticals, Inc.	NULL	Not Recruiting	Female: yes Male: yes	72	Phase 3	United States;Spain;Austria;Germany
4	EUCTR2014-003739-20-DE (EUCTR)	23/04/2015	21/01/2015	A clinical trial to see if ADS-5102 is safe in people with drug induced abnormal movements in Parkin ...	Open-Label Safety Study of ADS-5102 (Amantadine HCl) Extended Release Capsules for the Treatment of ...	Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease MedDRA version: 18.1;L ...	Product Name: Amantadine HCl Extended Release Capsule Product Code: ADS-5102 INN or Proposed INN: Aman ...	Adamas Pharmaceuticals, Inc.	NULL	Not Recruiting	Female: yes Male: yes	250	Phase 3	France;United States;Spain;Austria;Germany
5	EUCTR2014-003739-20-FR (EUCTR)	10/04/2015	19/06/2015	A clinical trial to see if ADS-5102 is safe in people with drug induced abnormal movements in Parkin ...	Open-Label Safety Study of ADS-5102 (Amantadine HCl) Extended Release Capsules for the Treatment of ...	Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease MedDRA version: 18.0;L ...	Product Name: Amantadine HCl Extended Release Capsule Product Code: ADS-5102 INN or Proposed INN: Aman ...	Adamas Pharmaceuticals, Inc.	NULL	Not Recruiting	Female: yes Male: yes	200	Phase 3	United States;France;Spain;Austria;Germany
6	EUCTR2014-003738-24-ES (EUCTR)	24/03/2015	16/02/2015	A clinical trial to see if ADS-5102 is safe and effective in people with drug induced abnormal movem ...	ADS-5102 (Amantadine HCl) Extended Release Efficacy and Safety Study in Parkinson's Disease Patients ...	Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease MedDRA version: 18.0;L ...	Product Name: Amantadine HCl Extended Release Capsule Product Code: ADS-5102 INN or Proposed INN: Aman ...	Adamas Pharmaceuticals, Inc.	NULL	Not Recruiting	Female: yes Male: yes	72	Phase 3	United States;Spain;Austria;Germany
7	EUCTR2014-003739-20-ES (EUCTR)	24/03/2015	16/02/2015	A clinical trial to see if ADS-5102 is safe in people with drug induced abnormal movements in Parkin ...	Open-Label Safety Study of ADS-5102 (Amantadine HCl) Extended Release Capsules for the Treatment of ...	Treatment of levodopa-induced dyskinesia in subjects with Parkinson's disease MedDRA version: 18.0;L ...	Product Name: Amantadine HCl Extended Release Capsule Product Code: ADS-5102 INN or Proposed INN: Aman ...	Adamas Pharmaceuticals, Inc.	NULL	Not Recruiting	Female: yes Male: yes	200	Phase 3	United States;Spain;Austria;Germany
8	EUCTR2014-001132-10-FR (EUCTR)	18/11/2014	18/06/2015	A 26 Week Clinical Study to Evaluate the Use of Long-Acting Amantadine to Treat Parkinson’s Disease ...	A Multicenter, Randomized, Placebo-controlled, Double-blind, 26 Week Study to Evaluate the Efficacy ...	Parkinson’s Disease Subjects with Levodopa-Induced Dyskinesias MedDRA version: 18.0;Level: PT;Classi ...	Product Name: Amantadine HCl Extended Release INN or Proposed INN: Amantadine hydrochloride Other desc ...	Osmotica Pharmaceutical Corp.	NULL	Authorised-recruitment may be ongoing or finished	Female: yes Male: yes	162		United States;France;Canada;Spain;Germany
9	EUCTR2014-001131-36-ES (EUCTR)	23/10/2014	03/09/2014	A 16 Week Clinical Study to Evaluate the Use of Long-Acting Amantadine to Treat Parkinson's Disease ...	A Multicenter, Randomized, Placebo-controlled, Double-blind, 16 Week Study to Evaluate the Efficacy ...	Parkinson's Disease Subjects with Levodopa-Induced Dyskinesias MedDRA version: 17.0;Level: PT;Classi ...	Product Name: Amantadine HCl Extended Release INN or Proposed INN: Amantadine hydrochloride Other desc ...	Osmotica Pharmaceutical Corp.	NULL	Not Recruiting	Female: yes Male: yes	162	Phase 3	France;United States;Canada;Spain;Germany
10	EUCTR2014-001132-10-ES (EUCTR)	23/10/2014	02/09/2014	A 26 Week Clinical Study to Evaluate the Use of Long-Acting Amantadine to Treat Parkinson's Disease ...	A Multicenter, Randomized, Placebo-controlled, Double-blind, 26 Week Study to Evaluate the Efficacy ...	Parkinson's Disease Subjects with Levodopa-Induced Dyskinesias MedDRA version: 17.0;Level: PT;Classi ...	Product Name: Amantadine HCl Extended Release INN or Proposed INN: Amantadine hydrochloride Other desc ...	Osmotica Pharmaceutical Corp.	NULL	Not Recruiting	Female: yes Male: yes	162	Phase 3	France;United States;Canada;Spain;Germany

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13. 多発性硬化症／視神経脊髄炎

臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2021-004868-95-ES (EUCTR)	26/05/2022	22/12/2021	AMANTADINE AND TRANSCRANIAL MAGNETIC STIMULATION FOR TREATING FATIGUE IN MULTIPLE SCLEROSIS	AMANTADINE AND TRANSCRANIAL MAGNETIC STIMULATION FOR TREATING FATIGUE IN MULTIPLE SCLEROSIS: PHASE I ...	Fatigue in multiple sclerosis;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: Amantadine Level Product Name: Amantadine INN or Proposed INN: INN Other descriptive name: ...	Fundación para la Inv. Biomédica Hospital Clínico San Carlos	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	144	Phase 4	Spain

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