Pramipexol
( DrugBank: Pramipexol / KEGG DRUG: Pramipexole )
1 disease
告示番号 | 疾患名(ページ内リンク) | 臨床試験数 |
---|---|---|
6 | パーキンソン病 | 129 |
6. パーキンソン病
臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199
Showing 1 to 10 of 129 trials
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | ChiCTR2000039050 | 2020-10-3020201030 | 2020-10-1420201014 | Efficacy of levodopa/carbidopa/entacapone in the replacement of Levodopa /dopa decarboxylase inhibitor in the treatment of 'Wearing-off' in Patients with Parkinson's disease in China: a multicenter, randomized controlled, open study Efficacy of levodopa/carbidopa/entacapone in the replacement of Levodopa /dopa decarboxylase inhibit ... | Efficacy of levodopa/carbidopa/entacapone in the replacement of Levodopa /dopa decarboxylase inhibitor in the treatment of 'Wearing-off' in Patients with Parkinson's disease in China: a multicenter, randomized controlled, open study Efficacy of levodopa/carbidopa/entacapone in the replacement of Levodopa /dopa decarboxylase inhibit ... | Parkinson's Disease | Group 1:adding pramipexole;Group 2:adding LCE; | The Affiliated Brain Hospital of Nanjing Medical University (Nanjing Brain Hospital) | NULL | Pending | 30 | 80 | Both | Group 1:175;Group 2:175; | Phase 4 | China |
2 | ChiCTR2000037624 | 2020-10-0120201001 | 2020-08-2920200829 | Clinical efficacy of dopamine agonist Pramipexol in the treatment of cognitive impairment in PATIENTS with PD-RBD and its population pharmacokinetic study Clinical efficacy of dopamine agonist Pramipexolin the treatment of cognitive impairment in PATIENTS ... | Clinical efficacy of dopamine agonist Pramipexol in the treatment of cognitive impairment in PATIENTS with PD-RBD and its population pharmacokinetic study Clinical efficacy of dopamine agonist Pramipexolin the treatment of cognitive impairment in PATIENTS ... | Parkinson's disease | experimental group:Pramipexol + dopa hydrazine combination therapy;control group: dopa hydrazine; | Shanghai General Hospital | NULL | Recruiting | 18 | 85 | Both | experimental group:50;control group:50; | China | |
3 | ChiCTR2000035564 | 2020-08-1720200817 | 2020-08-1320200813 | Pharmacokinetics and Bioequivalence study of Pramipexole Extended-Release Tablets in Healthy Chinese Volunteers Pharmacokinetics and Bioequivalence study of Pramipexole Extended-Release Tablets in Healthy Chinese ... | Pharmacokinetics and Bioequivalence study of Pramipexole Extended-Release Tablets in Healthy Chinese Volunteers Pharmacokinetics and Bioequivalence study of Pramipexole Extended-Release Tablets in Healthy Chinese ... | Parkinson’s disease | fasting administration group-TR:phase I: Pramipexole Extended-Release Tablets; phase II: Reference preparation;fasting administration group-RT:phase I: Reference preparation: pahse II: Test preparation;high-fat postprandial administration group-TR:phase I: Pramipexole Extended-Release Tablets; phase II: Reference preparation;high-fat postprandial administration group-RT:phase I: Pramipexole Extended-Release Tablets; phase II: Reference preparation; fasting administration group-TR:phase I: Pramipexole Extended-Release Tablets; phase II: Reference p ... | West China Hospital of Sichuan University | NULL | Recruiting | 18 | 65 | Both | fasting administration group-TR:28;fasting administration group-RT:28;high-fat postprandial administration group-TR:28;high-fat postprandial administration group-RT:28; | Phase 1 | China |
4 | NCT04275492 (ClinicalTrials.gov) | July 24, 202020200724 | 18/11/201920191118 | Study on Bioequivalence of Pramipexole Dihydrochloride Sustained Release Tablets | Study on Bioequivalence of Pramipexole Dihydrochloride Sustained Release Tablets | Parkinson's Disease | Drug: Praxol hydrochloride sustained release tablet Specification: 0.375mg/ tablet (in pramipexole hydrochloride);Drug: Pramipexole hydrochloride sustained-release tablet (Siforl®) Specification: 0.26mg/ tablet (in pramipexole) Drug: Praxol hydrochloride sustained release tablet Specification: 0.375mg/ tablet (in pramipexole h ... | First Affiliated Hospital of Zhejiang University | Hongguan biological pharmaceutical co. | Recruiting | 18 Years | 45 Years | All | 60 | N/A | China |
5 | NCT04249544 (ClinicalTrials.gov) | December 3, 201920191203 | 28/1/202020200128 | Social Decision Making in Parkinson's Disease | Cognitive and Neural Mechanisms of Impaired Social Decision-Making in Parkinson's Patients Taking Dopamine Agonists Cognitive and Neural Mechanisms of Impaired Social Decision-Making in Parkinson's Patients Taking Do ... | Parkinson Disease | Drug: Pramipexole;Drug: Placebo | Vanderbilt University Medical Center | United States Department of Defense | Recruiting | 45 Years | 80 Years | All | 60 | Phase 1 | United States |
6 | ChiCTR1900021708 | 2019-07-0120190701 | 2019-03-0520190305 | Study for the brain network mechanism of pramipexole in the treatment of tremor-type PD patients based on DRD3 Ser9Gly polymorphi Study for the brain network mechanism of pramipexole in the treatment of tremor-type PD patients bas ... | Study for the brain network mechanism of pramipexole in the treatment of tremor-type PD patients based on DRD3 Ser9Gly polymorphism Study for the brain network mechanism of pramipexole in the treatment of tremor-type PD patients bas ... | Parkinson's Disease | Healthy control group:No;tremor-dominant phenotype PD patients group:pramipexole; | Department of Neurology, Brain Hospital Affiliated to Nanjing Medical University | NULL | Pending | 50 | 70 | Both | Healthy control group:80;tremor-dominant phenotype PD patients group:80; | China | |
7 | ChiCTR1900022534 | 2019-06-0120190601 | 2019-04-1520190415 | Efficacy of entacapone and pramipexole for non-motor symptoms of Parkinson’s disease: a prospective randomized controlled trial Efficacy of entacapone and pramipexole for non-motor symptoms of Parkinson’s disease: a prospective ... | Efficacy of entacapone and pramipexole for non-motor symptoms of Parkinson’s disease: a prospective randomized controlled trial Efficacy of entacapone and pramipexole for non-motor symptoms of Parkinson’s disease: a prospective ... | non-motor symptoms of Parkinson’s disease | entacapone group:Patients in the entacapone group will be administered entacapone (Novartis; import drug registration certificate number: H20160680), 10 times per day, 200 mg each time, for 3 weeks. ;pramipexole group:Patients in the pramipexole group will be administered pramipexole (Boehringer-Ingelheim; import drug registration certificate number: 20140918) , 3 times per day, 1 mg each time, for 3 weeks.; entacapone group:Patients in the entacapone group will be administered entacapone (Novartis; import ... | Geriatric Hospital of Hainan | NULL | Pending | 40 | 75 | Both | entacapone group:194;pramipexole group:194; | N/A | China |
8 | NCT03845387 (ClinicalTrials.gov) | February 26, 201920190226 | 15/2/201920190215 | A Clinical Study of KDT-3594 in Patients With Early Parkinson's Disease. | A Phase II Clinical Study of KDT-3594 in Patients With Early Parkinson's Disease. | Parkinson Disease | Drug: KDT-3594;Drug: Pramipexole | Kissei Pharmaceutical Co., Ltd. | NULL | Completed | 20 Years | 79 Years | All | 74 | Phase 2 | Japan |
9 | ChiCTR1800019942 | 2018-12-3120181231 | 2018-12-0920181209 | A Multicenter Randomized Controlled Trial for Effect of Zishen Pingchan Granules Combined with Pramipexole in the treatment of Depression in Parkinson’s Disease A Multicenter Randomized Controlled Trial for Effect of Zishen Pingchan Granules Combined with Prami ... | A Multicenter Randomized Controlled Trial for Effect of Zishen Pingchan Granules Combined with Pramipexole in the treatment of Depression in Parkinson’s Disease A Multicenter Randomized Controlled Trial for Effect of Zishen Pingchan Granules Combined with Prami ... | Parkinson’s Disease | Experimental group:Zishen Pingchan Granules combined with Pramipexole;Control group:Zishen Pingchan Granules placebo combined with Pramipexole; Experimental group:Zishen Pingchan Granules combined with Pramipexole;Control group:Zishen Pingchan ... | The Affiliated Brain Hospital of Nanjing Medical University( Nanjing Brain Hospital) | NULL | Pending | 30 | 85 | Both | Experimental group:150;Control group:150; | China | |
10 | NCT03521635 (ClinicalTrials.gov) | July 3, 201820180703 | 11/4/201820180411 | The SUSTAIN Study Compares the Effects of Sustained and Immediate-release Pramipexole on the noctUrnal Symptoms of paTients With Advanced ParkInsoN's Disease Who Also Take L-Dopa The SUSTAIN Study Compares the Effects of Sustained and Immediate-release Pramipexole on the noctUrn ... | A Two- Stage Multicenter, Open-label, Randomized, Active Controlled Parallel Group Study Comparing the Efficacy and Safety of Pramipexole SR Versus Pramipexole IR Administered Orally Over an 18-week Treatment on Nocturnal Symptoms in L-Dopa+ Treated Patients With Advanced Parkinson's Disease (PD) A Two- Stage Multicenter, Open-label, Randomized, Active Controlled Parallel Group Study Comparing t ... | Parkinson Disease | Drug: Pramipexole SR;Drug: Pramipexole IR | Boehringer Ingelheim | NULL | Completed | 30 Years | N/A | All | 98 | Phase 4 | China |