SAM
( DrugBank: - / KEGG DRUG: - )
1 disease
告示番号 | 疾患名(ページ内リンク) | 臨床試験数 |
---|---|---|
6 | パーキンソン病 | 15 |
6. パーキンソン病
臨床試験数 : 2,307 / 薬物数 : 2,007 - (DrugBank : 349) / 標的遺伝子数 : 188 - 標的パスウェイ数 : 199
Showing 1 to 10 of 15 trials
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT05370079 (ClinicalTrials.gov) | September 16, 202220220916 | 6/5/202220220506 | Control Cohort CTRL COH | Control Cohort CTRL COH | Parkinson's Disease; Amyotrophic Lateral Sclerosis; Glioblastoma; Cancer Without Neurological Disease; Rheumatoid Polyarthritis Parkinson's Disease; Amyotrophic Lateral Sclerosis; Glioblastoma; Cancer Without Neurological Diseas ... | Biological: Collection of biological sample (blood and/or CSF) | Hospices Civils de Lyon | NULL | Not yet recruiting | 18 Years | N/A | All | 350 | N/A | France |
2 | NCT05699161 (ClinicalTrials.gov) | October 14, 202120211014 | 7/12/202220221207 | Adipose-derived Stromal Vascular Fraction Cells to Treat Parkinson | Treatment of Parkinson Disease With Transplantation of SVF Cells of Adipose Origin: Safety and Exploratory Efficacy Study Treatment of Parkinson Disease With Transplantation of SVF Cells of Adipose Origin: Safety and Explo ... | Idiopathic Parkinson Disease;Parkinson's Disease and Parkinsonism | Genetic: Adipose-derived stromal vascular fraction cells | Samuel Vilchez, PhD | Wake Forest University;Ministerio de Salud, Nicaragua;GID BIO, Inc.;National Autonomous University of Nicaragua Wake Forest University;Ministerio de Salud, Nicaragua;GID BIO, Inc.;National Autonomous University o ... | Completed | 18 Years | 80 Years | All | 10 | Phase 1/Phase 2 | Nicaragua |
3 | NCT03947216 (ClinicalTrials.gov) | October 23, 202020201023 | 7/5/201920190507 | Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist, to Treat Impulse Control Disorders in Parkinson's Disease. Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5 ... | Study of Pimavanserin Efficacy for the Treatment of Impulse Control Disorders in Parkinson's Disease Study of Pimavanserin Efficacy for the Treatment of Impulse Control Disorders in Parkinson's Disease ... | Parkinson Disease | Drug: Active drug: pimavanserin 17mg (2 strength tablets);Drug: Placebo: 2 tablets containing same excipients except active compound;Behavioral: Assessment of severity of ICD (impulse control disorders);Behavioral: Assessment of motor and non-motors symptoms of PD Evaluation of hyper- and hypodopaminergic behaviors;Behavioral: Assessment of quality of life;Behavioral: Assessment of depression;Behavioral: Assessment of cognition;Behavioral: Assessment of severity of Parkinson Disease;Procedure: Blood analysis;Procedure: Cardiac monitoring Drug: Active drug: pimavanserin 17mg (2 strength tablets);Drug: Placebo: 2 tablets containing same e ... | University Hospital, Strasbourg, France | NS-PARK;EUCLID Clinical Trial Platform;F-CRIN | Recruiting | 35 Years | 75 Years | All | 130 | Phase 2 | France |
4 | NCT04477161 (ClinicalTrials.gov) | September 5, 201920190905 | 22/6/202020200622 | Effect of Ketone Esters in Parkinson's Disease | Effect of Ketone Esters on Parkinson Disease: A Pilot, Prospective Trial. | Parkinson Disease;Ketosis | Dietary Supplement: Ketone Ester Elite endurance Nutrition Drink;Other: Stool Sample | University of Florida | NULL | Completed | 40 Years | 75 Years | All | 10 | N/A | United States |
5 | ChiCTR1800019216 | 2017-09-3020170930 | 2018-10-3120181031 | Study for accurate diagnosis and treatment of Parkinson's disease by using the combination of TMS-EEG Study for accurate diagnosis and treatment of Parkinson's disease by using the combination of TMS-EE ... | Study for accurate diagnosis and treatment of Parkinson's disease by using the combination of TMS-EEG Study for accurate diagnosis and treatment of Parkinson's disease by using the combination of TMS-EE ... | Parkinson's disease | Bradykinesia Group:Sick side, SAM region, 10Hz rTMS;Tremor Group:Sick side, M1 region, 1Hz rTMS;Health control:N/A; Bradykinesia Group:Sick side, SAMregion, 10Hz rTMS;Tremor Group:Sick side, M1 region, 1Hz rTMS;Healt ... | Shenzhen People's Hospital | NULL | Recruiting | 50 | 80 | Both | Bradykinesia Group:30;Tremor Group:30;Health control:30; | China | |
6 | JPRN-UMIN000022022 | 2016/05/1020160510 | 10/05/201620160510 | A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic constipation in patients with Parkinson disease A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic co ... | A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic constipation in patients with Parkinson disease - A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic constipation in patients with Parkinson disease A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic co ... | Parkinson diseaseChronic constipation | Study drug group: A 12-week administration of lubiprostone 24 microrgrum (adjustable) twice daily after switching from magnesium oxide Control group: Continuous administration of magnesium oxide at the same dosage regimen as before the enrollment Study drug group: A 12-week administration of lubiprostone 24 microrgrum (adjustable) twice daily af ... | Dokkyo Medical University | NULL | Complete: follow-up complete | 20years-old | 90years-old | Male and Female | 64 | Not selected | Japan |
7 | JPRN-UMIN000022023 | 2016/05/1020160510 | 10/05/201620160510 | A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic constipation in patients with Parkinson disease. -to evaluation by change of intestinal bacterial flora- A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic co ... | A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic constipation in patients with Parkinson disease. -to evaluation by change of intestinal bacterial flora- - A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic constipation in patients with Parkinson disease. -to evaluation by change of intestinal bacterial flora- A randomized controlled study comparing lubiprostone and magnesium oxide for treatment of chronic co ... | Parkinson diseaseChronic constipation | Study drug group: A 12-week administration of lubiprostone 24 microgrum (adjustable) twice daily after switching from magnesium oxide Control group: Continuous administration of magnesium oxide at the same dosage regimen as before the enrollmen Study drug group: A 12-week administration of lubiprostone 24 microgrum (adjustable) twice daily aft ... | Dokkyo Medical University | NULL | Complete: follow-up complete | 20years-old | 90years-old | Male and Female | 64 | Not selected | Japan |
8 | NCT02775591 (ClinicalTrials.gov) | April 201620160400 | 9/5/201620160509 | Effect of Short-term Motilitone Therapy on Health-related Quality of Life in PD Patients With Gastrointestinal Symptoms Effect of Short-term Motilitone Therapy on Health-related Quality of Life in PD Patients With Gastro ... | Effect of Short-term Motilitone Therapy on Health-related Quality of Life in Parkinson's Disease Patients With Gastrointestinal Symptoms: a Multicenter, Double-blind Randomized, Placebo-controlled Trial Effect of Short-term Motilitone Therapy on Health-related Quality of Life in Parkinson's Disease Pat ... | Parkinson Disease;Dyspepsia | Drug: DA-9701;Drug: DA-9701 placebo | Seoul National University Hospital | Samsung Medical Center;Korea University Guro Hospital;Hanyang University;Seoul Veterans Hospital;SMG-SNU Boramae Medical Center Samsung Medical Center;Korea University Guro Hospital;Hanyang University;Seoul Veterans Hospital;SMG ... | Completed | 50 Years | 80 Years | All | 147 | Phase 4 | Korea, Republic of |
9 | NCT02769793 (ClinicalTrials.gov) | June 201520150600 | 9/5/201620160509 | Efficacy of Levodopa/Benserazide Dispersible Tablet on Response Fluctuations in PD Patients With Delayed ON Efficacy of Levodopa/Benserazide Dispersible Tablet on Response Fluctuations in PD Patients With Del ... | Efficacy of Levodopa/Benserazide Dispersible Tablet on Response Fluctuations in Parkinson's Disease Patients With Delayed ON: a Multicenter Randomized Open-label Cross-over Trial Efficacy of Levodopa/Benserazide Dispersible Tablet on Response Fluctuations in Parkinson's Disease ... | Parkinson Disease | Drug: Levodopa dispersible;Drug: Levodopa | Seoul National University Hospital | SMG-SNU Boramae Medical Center;Samsung Medical Center | Completed | 31 Years | 80 Years | All | 40 | Phase 4 | Korea, Republic of |
10 | JPRN-UMIN000046104 | 2013/03/0120130301 | 21/11/202120211121 | Research for the development of assessment strategy and treatment for cognitive impairment of Parkinson's disease Research for the development of assessment strategy and treatment for cognitive impairment of Parkin ... | Neuroimaging study for the assessment and treatment of cognitive impairment of the patients with Parkinson's disease - RCIP-Nagoya Study: Research for the cognitive impairment of Parkinson's disease in Nagoya Neuroimaging study for the assessment and treatment of cognitive impairment of the patients with Par ... | Parkinson's disease | This study followed a randomized double-blind crossover design for the patients with mild cognitive impairments in PD. Patients in the memantine group were given memantine at 5 mg/day in the first week, and the dose was increased by 5 mg/day per week, with the final dose of 20 mg/day. The patients in the placebo group were given a placebo following the same regimen. During maximum dose administration, fMRI scanning and neuropsychological tests were performed. Group comparisons between memantine and placebo were performed to explore the significant differences. This study followed a randomized double-blind crossover design for the patients with mild cognitive ... | Nagoya City University | NULL | Complete: follow-up complete | 60years-old | 75years-old | Male and Female | 12 | Not applicable | Japan |