MACITENTAN TABLETS

( DrugBank: Macitentan / KEGG DRUG: Macitentan )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
86	肺動脈性肺高血圧症	23

告示番号	疾患名（ページ内リンク）	臨床試験数
88	慢性血栓塞栓性肺高血圧症	10

86. 肺動脈性肺高血圧症

臨床試験数 : 1,205 / 薬物数 : 684 - (DrugBank : 124) / 標的遺伝子数 : 100 - 標的パスウェイ数 : 193

trials per page:

Showing 1 to 10 of 23 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2019-004131-24-PT (EUCTR)	16/12/2022	25/08/2022	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Russian Federation;Singapore;United States;Czechia;Thailand;Portugal;Saudi Arabia;Austria;China;Kore ...
2	EUCTR2019-002533-11-BG (EUCTR)	08/11/2021	02/09/2021	A Phase 3 study to compare long-term efficacy and safety of macitentan75 mg versus 10 mg in Pulmonar ...	A Phase 3, Prospective, Multicenter, Double-blind, Double-dummy, Randomized, Active-controlled, Para ...	Pulmonary arterial hypertension MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pu ...	Trade Name: Opsumit® Product Name: macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmacteuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	900	Phase 3	Serbia;Portugal;Belarus;United States;Taiwan;Slovakia;Thailand;Spain;Ukraine;Russian Federation;Isra ...
3	JPRN-jRCT2061200058 (jRCT2061200058)	23/06/2021	19/02/2021	Outcome Study Assessing a 75 milligrams (mg) Dose of Macitentanin Patients with Pulmonary Arterial H ...	A Phase 3, Prospective, Multicenter, Double-blind, Double-dummy, Randomized, Active-controlled, Para ...	Pulmonary Arterial Hypertension	Macitentan10 mg: Participants will receive macitentan10 mg film-coated tabletsorally. Macitentan37.5 ...	Nakano Masayoshi	NULL	Recruiting	>= 18age old	Not applicable	Both	900	Phase 3	Argentina;Australia;Austria;Belarus;Belgium;Brazil;Canada;China;Colombia;Czechia;Denmark;France;Germ ...
4	EUCTR2019-004131-24-GB (EUCTR)	23/11/2020	26/05/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	United States;United Arab Emirates;Serbia;Taiwan;Saudi Arabia;Slovakia;Spain;Ukraine;Israel;Russian ...
5	EUCTR2019-002533-11-AT (EUCTR)	12/11/2020	04/09/2020	A Phase 3 study to compare long-term efficacy and safety of macitentan75 mg versus 10 mg in Pulmonar ...	A Phase 3, Prospective, Multicenter, Double-blind, Double-dummy, Randomized, Active-controlled, Para ...	Pulmonary arterial hypertension MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pu ...	Trade Name: Opsumit® Product Name: macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmacteuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	900	Phase 3	United States;Serbia;Belarus;Portugal;Taiwan;Slovakia;Thailand;Spain;Ukraine;Russian Federation;Isra ...
6	EUCTR2019-002533-11-SK (EUCTR)	12/11/2020	13/08/2020	A Phase 3 study to compare long-term efficacy and safety of macitentan75 mg versus 10 mg in Pulmonar ...	A Phase 3, Prospective, Multicenter, Double-blind, Double-dummy, Randomized, Active-controlled, Para ...	Pulmonary arterial hypertension MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pu ...	Trade Name: Opsumit® Product Name: macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmacteuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	900	Phase 3	Serbia;Portugal;Belarus;United States;Taiwan;Slovakia;Thailand;Spain;Ukraine;Russian Federation;Isra ...
7	EUCTR2019-004131-24-LT (EUCTR)	10/11/2020	22/09/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Serbia;United States;Saudi Arabia;Taiwan;Slovakia;Spain;Ukraine;Russian Federation;Israel;Colombia;I ...
8	EUCTR2019-002533-11-NO (EUCTR)	29/10/2020	03/08/2020	A Phase 3 study to compare long-term efficacy and safety of macitentan75 mg versus 10 mg in Pulmonar ...	A Phase 3, Prospective, Multicenter, Double-blind, Double-dummy, Randomized, Active-controlled, Para ...	Pulmonary arterial hypertension MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pu ...	Trade Name: Opsumit® Product Name: macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmacteuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	900	Phase 3	Serbia;Portugal;United States;Belarus;Taiwan;Slovakia;Thailand;Spain;Ukraine;Russian Federation;Isra ...
9	JPRN-JapicCTI-194971	23/10/2020	25/09/2019	Clinical study to compare the efficacy and safety of macitentanand tadalafil monotherapies with the ...	Prospective, Multi-center, Double-blind, Randomized, Active-controlled, Triple-dummy, Parallel-group ...	pulmonary arterial hypertension	Intervention name : ACT-064992D INN of the intervention : - Dosage And administration of the intervent ...	Janssen Pharmaceutical K.K.	NULL	complete	18		BOTH	170	Phase 3	Japan, South America, Europe
10	EUCTR2019-002533-11-NL (EUCTR)	29/09/2020	29/04/2020	A Phase 3 study to compare long-term efficacy and safety of macitentan75 mg versus 10 mg in Pulmonar ...	A Phase 3, Prospective, Multicenter, Double-blind, Double-dummy, Randomized, Active-controlled, Para ...	Pulmonary arterial hypertension MedDRA version: 21.1;Level: PT;Classification code 10064911;Term: Pu ...	Trade Name: Opsumit® Product Name: macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmacteuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	655	Phase 3	United States;Portugal;Taiwan;Slovakia;Thailand;Spain;Ukraine;Israel;Russian Federation;Italy;France ...

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88. 慢性血栓塞栓性肺高血圧症

臨床試験数 : 157 / 薬物数 : 107 - (DrugBank : 22) / 標的遺伝子数 : 14 - 標的パスウェイ数 : 54

trials per page:

Showing 1 to 10 of 10 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05140525 (ClinicalTrials.gov)	June 1, 2023	28/10/2021	Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodyna ...	Effects of Combination Medical Therapy Followed by Balloon Pulmonary Angioplasty on Right Ventricula ...	CTEPH	Drug: Macitentan Tablets;Drug: Riociguat;Device: balloon pulmonary angioplasty	Dr Sudarshan Rajagopal	Actelion	Not yet recruiting	18 Years	N/A	All	15	Phase 3	United States
2	EUCTR2019-004131-24-PT (EUCTR)	16/12/2022	25/08/2022	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Russian Federation;Singapore;United States;Czechia;Thailand;Portugal;Saudi Arabia;Austria;China;Kore ...
3	JPRN-jRCT2051200150 (jRCT2051200150)	12/07/2021	11/03/2021	A study to evaluate efficacy and safety of macitentan75 mg in inoperable or persistent/recurrent chr ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension	Macitentan Participant will receive macitentanat a dose of 10 milligram (mg) once daily (OD) for 4 we ...	Nakano Masayoshi	NULL	Recruiting	>= 18age old	<= 80age old	Both	144	Phase 3	USA;Germany;Hungary;South Korea;Japan
4	EUCTR2019-004131-24-GB (EUCTR)	23/11/2020	26/05/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	United States;United Arab Emirates;Serbia;Taiwan;Saudi Arabia;Slovakia;Spain;Ukraine;Israel;Russian ...
5	EUCTR2019-004131-24-LT (EUCTR)	10/11/2020	22/09/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Serbia;United States;Saudi Arabia;Taiwan;Slovakia;Spain;Ukraine;Russian Federation;Israel;Colombia;I ...
6	EUCTR2019-004131-24-DE (EUCTR)	10/08/2020	26/05/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Serbia;United States;Saudi Arabia;Taiwan;Slovakia;Spain;Ukraine;Russian Federation;Israel;Colombia;I ...
7	EUCTR2019-004131-24-HU (EUCTR)	27/07/2020	28/05/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Serbia;United States;United Arab Emirates;Saudi Arabia;Taiwan;Slovakia;Spain;Ukraine;Russian Federat ...
8	EUCTR2019-004131-24-PL (EUCTR)	02/07/2020	02/06/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Serbia;United States;Saudi Arabia;Taiwan;Slovakia;Spain;Ukraine;Russian Federation;Israel;Colombia;I ...
9	EUCTR2019-004131-24-IT (EUCTR)	01/07/2020	14/06/2021	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: [JNJ-67896062/ ACT-064992] INN or P ...	ACTELION PHARMACEUTICALS LTD	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	Serbia;United States;Saudi Arabia;Taiwan;Slovakia;Spain;Ukraine;Russian Federation;Israel;Colombia;I ...
10	EUCTR2019-004131-24-ES (EUCTR)	05/06/2020	20/07/2020	A Phase 3 study to evaluate whether macitentan75 mg is an effective and safe treatment for patients ...	A prospective, randomized, double-blind, multicenter, placebo-controlled, parallel group, adaptive P ...	Chronic thromboembolic pulmonary hypertension MedDRA version: 21.1;Level: PT;Classification code 100 ...	Trade Name: Opsumit® Product Name: Macitentan tablets Product Code: JNJ-67896062 / ACT-064992 INN or Pr ...	ACTELION Pharmaceuticals Ltd.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	230	Phase 3	United States;United Arab Emirates;Serbia;Saudi Arabia;Taiwan;Slovakia;Spain;Ukraine;Israel;Russian ...

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