Methotrexate treatment

( DrugBank: Methotrexate / KEGG DRUG: Methotrexate )

2 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
41	巨細胞性動脈炎	3

告示番号	疾患名（ページ内リンク）	臨床試験数
46	悪性関節リウマチ	530

41. 巨細胞性動脈炎

臨床試験数 : 131 / 薬物数 : 139 - (DrugBank : 36) / 標的遺伝子数 : 33 - 標的パスウェイ数 : 125

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03892785 (ClinicalTrials.gov)	January 27, 2020	26/3/2019	MEthotrexateVersus TOcilizumab for Treatmentof GIant Cell Arteritis: a Multicenter, Randomized, Cont ...	MEthotrexateVersus TOcilizumab for Treatmentof GIant Cell Arteritis: a Multicenter, Randomized, Cont ...	Giant Cell Arteritis	Drug: Prednisone treatment;Drug: Tocilizumab treatment;Drug: Methotrexate treatment;Other: Questionn ...	Centre Hospitalier Universitaire Dijon	NULL	Recruiting	50 Years	N/A	All	230	Phase 3	France
2	EUCTR2018-002826-22-FR (EUCTR)	07/03/2019	21/11/2018	MEthotrexateversus TOcilizumab for treatmentof GIant cell Arteritis: a multicenter, randomized, cont ...	MEthotrexateversus TOcilizumab for treatmentof GIant cell Arteritis: a multicenter, randomized, cont ...	MedDRA version: 20.0;Level: LLT;Classification code 10018250;Term: Giant cell arteritis;System Organ ...	Trade Name: METOJECT Trade Name: RoActemra	CHU Dijon Bourgogne	NULL	Authorised-recruitment may be ongoing or finished			Female: no Male: no	200	Phase 3	France
3	NCT00004686 (ClinicalTrials.gov)	February 1994	24/2/2000	Phase II Randomized Study of Glucocorticoids With or Without Methotrexatefor Treatmentof Giant Cell ...		Giant Cell Arteritis	Drug: methotrexate;Drug: prednisone	The Cleveland Clinic	NULL	Completed	50 Years	N/A	Both	300	Phase 2	NULL

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46. 悪性関節リウマチ

臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228

trials per page:

Showing 1 to 10 of 530 trials

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05604885 (ClinicalTrials.gov)	November 30, 2022	31/10/2022	A Dose-range Study of the Safety and Efficacy of Treatmentin Adult Rheumatoid Arthritis Patients Wit ...	A Two-part, Randomized, Double-blind, Multi-center, Placebo-controlled Study of the Dose-range, Safe ...	Rheumatoid Arthritis	Drug: AP1189, 60 mg;Drug: AP1189, 80 mg;Drug: AP1189, 100 mg;Drug: Placebo	SynAct Pharma Aps	NBCD A/S	Recruiting	18 Years	85 Years	All	420	Phase 2	Moldova, Republic of
2	ITMCTR2200006086	2022-07-01	2022-06-10	Multicenter randomized double-blind clinical trial of Qufeng Zhitong Capsule combined with Methotrex ...	Multicenter randomized double-blind clinical trial of Qufeng Zhitong Capsule combined with Methotrex ...	rheumatoid arthritis	matched group:Methotrexatetablet + qufeng analgesic capsule simulato;experimental group:Methotrexate ...	Guang 'anmen Hospital, China Academy of Traditional Chinese Medicine	NULL	Pending	18	75	Both	matched group:100;experimental group:100;	Phase 4	China
3	NCT05363891 (ClinicalTrials.gov)	June 15, 2022	2/5/2022	Natrunix or Placebo in Combination With Methotrexate in Rheumatoid Arthritis	Phase II, Double-blind, Placebo-Controlled, Randomized Trial Examining Natrunix in Combination With ...	Rheumatoid Arthritis	Drug: Natrunix;Drug: Placebo	XBiotech, Inc.	NULL	Not yet recruiting	18 Years	N/A	All	150	Phase 2	NULL
4	NCT05363917 (ClinicalTrials.gov)	June 15, 2022	2/5/2022	Natrunix Versus Methotrexate in Rheumatoid Arthritis	Phase II Double-Blinded, Placebo-Controlled Randomized Study Examining the Safety and Efficacy of Na ...	Rheumatoid Arthritis	Drug: Natrunix with MTX placebo (+folate);Drug: Natrunix placebo with MTX (+folate)	XBiotech, Inc.	NULL	Not yet recruiting	18 Years	N/A	All	150	Phase 2	NULL
5	NCT05245448 (ClinicalTrials.gov)	February 22, 2022	22/1/2022	Tetrandrine in the Treatment of Rheumatoid Arthritis	Comparing the Efficacy of Tetrandrine Combined With Methotrexateand MethotrexateAlone in the Treatme ...	Rheumatoid Arthritis	Drug: Tetrandrine;Drug: Placebo	Peking University People's Hospital	NULL	Not yet recruiting	18 Years	65 Years	All	240	N/A	China
6	EUCTR2020-000350-96-DE (EUCTR)	11/01/2022	07/07/2021	Efficacy of Abatacept vs Adalimumab in Early, Autoantibody positive Rheumatoid Arthritis (RA) and wh ...	A Randomized, Head-to-head, Single-blind Study to Compare the Response to Treatmentwith Subcutaneous ...	Rheumatoid Arthritis MedDRA version: 23.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Trade Name: Orencia Product Name: Abatacept Product Code: BMS-188667 INN or Proposed INN: ABATACEPT Trad ...	Bristol-Myers Squibb International Corporation	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	400	Phase 3	United States;Czechia;Taiwan;Spain;United Kingdom;Italy;Switzerland;France;Czech Republic;Mexico;Arg ...
7	ChiCTR2200055292	2022-01-04	2022-01-05	Correlation between the changes of serum cytokines and immune cell subsets levels and curative effec ...	Correlation between the changes of serum cytokines and immune cell subsets levels and curative effec ...	Rheumatoid Arthritis	Experimental group:Yisaipu combined with methotrexate and folic acid;	Peking University People's Hospital	NULL	Recruiting	18	65	Both	Experimental group:140;	Phase 4	China
8	NCT05626348 (ClinicalTrials.gov)	December 22, 2021	15/11/2022	The Clinical Efficacy of Immunomodulators in RA Patients	The Clinical Study to Observe the Efficacy and Safety of Immunomodulators in Rheumatoid Arthritis Pa ...	Arthritis, Rheumatoid	Drug: Iguratimod;Drug: Methotrexate;Drug: Adalimumab Injection;Drug: Leflunomide;Drug: Hydroxychloro ...	Qilu Hospital of Shandong University	NULL	Recruiting	18 Years	80 Years	All	400	Phase 4	China
9	ChiCTR2100053999	2021-12-01	2021-12-06	Clinical Study on Treatmentof Damp Heat Stagnation Syndrome of Rheumatoid Arthritis by SiMiaoXiaoLin ...	Clinical Study on Treatmentof Damp Heat Stagnation Syndrome of Rheumatoid Arthritis by SiMiaoXiaoLin ...	Rheumatism	Experimental group:Simiaoxiaoling Zhiwang Decoction (granule) + methotrexate+ folic acid tablets;Con ...	Yunnan Hospital of Traditional Chinese Medicine	NULL	Recruiting	18	70	Both	Experimental group:36;Control group:36;		China
10	ChiCTR2100054305	2021-12-01	2021-12-13	Observation on the clinical efficacy of Jiawei Qianyang Fengsui Dan in the treatmentof RA with mixed ...	Observation on the clinical efficacy of Jiawei Qianyang Fengsui Dan in the treatmentof RA with mixed ...	Rheumatoid Arthritis	Treatmentgroup:Modified Qianyang Fengsui Dan + MethotrexateTablets + Folic Acid Tablets;Control grou ...	Yunnan Provincial Hospital of Traditional Chinese Medicine	NULL	Recruiting	18	70	Both	Treatment group:36;Control group:36;		China

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