DDrare: Database of Drug Development for Rare Diseases

215. ファロー四徴症
［臨床試験数：19，薬物数：35（DrugBank：16），標的遺伝子数：16，標的パスウェイ数：47］

Searched query = "Tetralogy of Fallot", "Fallot tetralogy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = AS; CPX; Calcium; Calcium gluconate; Coenzyme Q10; Device: Cellvizio 100 Series System with Confocal Miniprobes; Dexmedetomidine; Dobutamin; Dobutamine; Eplerenone; Fentanyl; Fentanyl (High Dose); Fentanyl (Low Dose); Fentanyl (Low Dose) + Dexmedetomidine; Fluorescite; Gradient; Ketamine; LOSARTAN POTASSIUM; Losartan; Losartan Potassium; Other: Transthoracic echocardiography at rest, during PLR, HG and CPX (including blood gas analysis in both groups). Additionally Fallot patients will undergo routine blood testings.; Other: dobutamine; PV; Potassium; Procedure: B-lines SE; Procedure: Coronary flow reserve SE; Procedure: Diastolic function SE; Procedure: Left ventricular contractile reserve SE; Procedure: Left ventricular outflow tract gradient SE; Procedure: Mitral regurgitation SE; Procedure: Pulmonary hemodynamics SE; Procedure: TOF repair with trans-annular patch VS preservation of PV; Recombinant human brain natriuretic peptide (rhBNP); Sodium citrate; Tranexamic acid

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00557934 (ClinicalTrials.gov)	October 2007	13/11/2007	Right Ventricular Contractility Reserve Following Repair of Tetralogy of Fallot	Evaluation of Right Ventricular Contractility Reserve Function During Dobutamine Stress in Patients Following Surgical Repair of Tetralogy of Fallot	Right Ventricular Dysfunction	Other: dobutamine	University Hospital Tuebingen	Fördergemeinschaft Deutsche Kinderherzzentren, Bonn, Germany	Completed	4 Years	N/A	Both	16	N/A	Germany

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT00557934
(ClinicalTrials.gov)

October 2007

13/11/2007

Right Ventricular Contractility Reserve Following Repair of Tetralogy of Fallot

Evaluation of Right Ventricular Contractility Reserve Function During Dobutamine Stress in Patients Following Surgical Repair of Tetralogy of Fallot

Right Ventricular Dysfunction

Other: dobutamine

University Hospital Tuebingen

Fördergemeinschaft Deutsche Kinderherzzentren, Bonn, Germany

Completed

4 Years

N/A

Both

N/A

Germany