DDrare: Database of Drug Development for Rare Diseases

83. アジソン病
［臨床試験数：20，薬物数：42（DrugBank：13），標的遺伝子数：6，標的パスウェイ数：17］

Searched query = "Addison disease", "Primary chronic adrenocortical insufficiency", "Autoimmune polyglandular syndrome", "Hypoparathyroidism-Addison-Monilia syndrome", "HAM syndrome", "Schmidt syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Acetate; Cortef; Cortef (hydrocortisone); Cortef 5 mg; Cosyntropin; Dehydroepiandrosterone; Depot tetracosactide; Device: 30-hour ambulatory sampling of intestinal fluid; Dexamethasone; Diagnostic Test: Baseline blood tests; Diagnostic Test: Cosyntropin stimulation test; Grapefruit; Grapefruit Juice; HYDROCORTISONE HYDROGEN SUCCINATE; HYDROCORTISONE ROUSSEL; HYDROCORTISONE SODIUM SUCCINATE; Hydrocortison 100 mg (Pfizer®) in 2 ml solvent; Hydrocortisone; Hydrocortisone 100mg/ml; Hydrocortisone Roussel; Hydrocortisone hydrogen succinate; Hydrocortisone sodium phosphate; Hydrocortisonum; Hydrogen; Hydrokortison APL kapsel 2,5 mg; Isocaloric Diet; Liquorice; MabThera; Mabthera Infusion; Mabthera infusion; Medrone; Methylprednisolone; Phosphate; Rituximab; Solu-Cortef; Solu-Cortef (hydrocortisone); Solu-Medrone; Solu-cortef; Solu-medrone; Synacthen Depot; Tetracosactide; Tetracosactide acetate

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03793114 (ClinicalTrials.gov)	September 26, 2018	6/11/2018	Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's Disease	Residual Secretion of Adrenal Steroid Hormones in Addison's Disease	Primary Adrenal Insufficiency	Diagnostic Test: Cosyntropin stimulation test;Diagnostic Test: Baseline blood tests;Device: 30-hour ambulatory sampling of intestinal fluid	University of Bergen	Karolinska Institutet;Charite University, Berlin, Germany	Recruiting	18 Years	70 Years	All	200	N/A	Germany;Norway;Sweden
2	NCT01371526 (ClinicalTrials.gov)	September 2010	9/3/2011	Revival of Stem Cells in Addison's Study	Revival of Autochthonous Adrenocortical Stem Cells in Autoimmune Addison's Disease	Adrenal Failure	Drug: depot tetracosactide	Newcastle University	NULL	Completed	16 Years	66 Years	Both	13	Phase 4	United Kingdom

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT03793114
(ClinicalTrials.gov)

September 26, 2018

6/11/2018

Screening and Stimulation Testing for Residual Secretion of Adrenal Steroid Hormones in Autoimmune Addison's Disease

Residual Secretion of Adrenal Steroid Hormones in Addison's Disease

Primary Adrenal Insufficiency

Diagnostic Test: Cosyntropin stimulation test;Diagnostic Test: Baseline blood tests;Device: 30-hour ambulatory sampling of intestinal fluid

University of Bergen

Karolinska Institutet;Charite University, Berlin, Germany

Recruiting

18 Years

70 Years

All

200

N/A

Germany;Norway;Sweden

NCT01371526
(ClinicalTrials.gov)

September 2010

9/3/2011

Revival of Stem Cells in Addison's Study

Revival of Autochthonous Adrenocortical Stem Cells in Autoimmune Addison's Disease

Adrenal Failure

Drug: depot tetracosactide

Newcastle University

NULL

Completed

16 Years

66 Years

Both

Phase 4

United Kingdom