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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
10.9% Sodium Chloride Injection2件: Chloride ion,
Sodium chloride		1件: D02056 --1件: 168
2ACER-002 (celiprolol) 200 mg BID1件: Celiprolol1件: D07660 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 168
3AR101----1件: 168
4Bupivacaine1件: Bupivacaine1件: D07552 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬8件: 46, 51, 53, 70, 96, 168, 226, 298
5Bupivacaine Injection 0.5%1件: Bupivacaine1件: D07552 5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 168
6Celiprolol1件: Celiprolol1件: D07660 1件: ADRB1 💬11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 168
7Chloride1件: Chloride ion---28件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 97, 107, 127, 168, 171, 193, 227, 228, 251, 288, 296, 297, 299, 338
8Control----4件: 6, 46, 168, 299
9Enzastaurin1件: Enzastaurin1件: D11935 1件: PRKCB 💬71件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Amoebiasis, Amphetamine addiction, B cell receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Circadian entrainment, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, EGFR tyrosine kinase inhibitor resistance, Endocrine and other factor-regulated calcium reabsorption, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, GABAergic synapse, Gap junction, Gastric acid secretion, Glioma, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Insulin secretion, Leishmaniasis, Leukocyte transendothelial migration, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, Pancreatic secretion, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phosphatidylinositol signaling system, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Sphingolipid signaling pathway, Spinocerebellar ataxia, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, mTOR signaling pathway 💬1件: 168
10ENZASTAURIN HYDROCHLORIDE1件: Enzastaurin1件: D11935 1件: PRKCB 💬71件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Amoebiasis, Amphetamine addiction, B cell receptor signaling pathway, Calcium signaling pathway, Carbohydrate digestion and absorption, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Choline metabolism in cancer, Cholinergic synapse, Circadian entrainment, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Dopaminergic synapse, EGFR tyrosine kinase inhibitor resistance, Endocrine and other factor-regulated calcium reabsorption, ErbB signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, GABAergic synapse, Gap junction, Gastric acid secretion, Glioma, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatitis B, Hepatocellular carcinoma, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Inflammatory mediator regulation of TRP channels, Influenza A, Insulin resistance, Insulin secretion, Leishmaniasis, Leukocyte transendothelial migration, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanogenesis, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, Non-small cell lung cancer, Oxytocin signaling pathway, Pancreatic secretion, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phosphatidylinositol signaling system, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Sphingolipid signaling pathway, Spinocerebellar ataxia, Thyroid hormone signaling pathway, Thyroid hormone synthesis, VEGF signaling pathway, Vascular smooth muscle contraction, Wnt signaling pathway, mTOR signaling pathway 💬1件: 168
11IRBESARTAN1件: Irbesartan1件: D00523 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222
12Lidocaine1件: Lidocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬12件: 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 256
13Lidocaine Injection 2%1件: Lidocaine2件: D00358 ,
D08127 		5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 168
14Mecasermin1件: Mecasermin1件: D03297 2件: GHR,
IGF1R 💬		33件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬5件: 78, 96, 168, 265, 299
15Mind-body therapy----1件: 168
16Oxygen1件: Oxygen1件: D00003 --13件: 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
17Oxytocin1件: Oxytocin1件: D00089 1件: OXTR 💬4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬7件: 6, 72, 127, 168, 193, 206, 226
18Riboflavin1件: Riboflavin1件: D00050 --7件: 38, 46, 96, 97, 162, 168, 265
19Saline----10件: 6, 13, 17, 53, 67, 78, 86, 97, 168, 299
20Sodium chloride2件: Chloride ion,
Sodium chloride		1件: D02056 --20件: 6, 11, 13, 14, 34, 41, 46, 50, 51, 53, 60, 67, 70, 96, 168, 193, 227, 228, 288, 299