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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
100244301----1件: 274
2Aclasta----3件: 13, 271, 274
3Actonel 5mg Film Coated Tablets1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
4Actonel Once a Week 35 mg film-coated tablets1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
5Actonel/Optinate 5mg film-coated tablets1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
6Alendronate1件: Alendronic acid1件: D07119 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 19, 41, 46, 50, 271, 274, 299
7ALENDRONIC ACID1件: Alendronic acid1件: D07119 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬2件: 46, 274
8Alternative osteoporosis medications----1件: 274
9AMG 162----2件: 46, 274
10AMG 785----1件: 274
11ANTI-SCLEROSTIN MONOCLONAL ANTIBODY----1件: 274
12Bisphosphonates----2件: 6, 274
13Blood sample----20件: 8, 13, 46, 49, 51, 53, 61, 66, 84, 88, 96, 97, 107, 127, 235, 274, 280, 288, 294, 299
14Bone marrow transplant----1件: 274
15Bone marrow-derived mesenchymal stromal cells (MSCs)1件: Human Umbilical Cord Mesenchymal Stem Cells---1件: 274
16Bonefos1件: Clodronic acid1件: D03545 --1件: 274
17BOOST cells----1件: 274
18BPS804----2件: 172, 274
19BPS804, UX143----1件: 274
20Busulfan1件: Busulfan1件: D00248 --13件: 19, 20, 28, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326
21Calcichew D3----1件: 274
22Calcichew tablets----1件: 274
23Calcio1件: Calcium---4件: 13, 96, 97, 274
24Calcio carbonato2件: Calcium,
Calcium carbonate		2件: D00932 ,
D10802 		--1件: 274
25CALCIO CARBONATO/COLECALCIFEROLO2件: Calcium,
Calcium carbonate		2件: D00932 ,
D10802 		--1件: 274
26Calcium1件: Calcium---27件: 6, 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 156, 214, 215, 222, 224, 235, 265, 274, 298, 299
27Calcium D31件: Calcium---1件: 274
28CALCIUM D3 SANDOZ - 1000 MG + 880 U.I. COMPRESSE EFFERVESCENTI 30 COMPRESSE DIVISIBILI1件: Calcium---1件: 274
29Celulas madre mesenquimales troncales adultas alogenicas de médula ósea no expandida----1件: 274
30Clasteon1件: Clodronic acid1件: D03545 --1件: 274
31Cyclophosphamide1件: Cyclophosphamide2件: D00287 ,
D07760 		--44件: 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 85, 93, 96, 162, 164, 172, 205, 222, 224, 256, 274, 283, 284, 285, 288, 326, 331
32Cyclosporin1件: Cyclosporine1件: D00184 5件: PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬17件: 38, 46, 49, 50, 53, 56, 60, 62, 63, 93, 95, 97, 113, 164, 222, 274, 326
33Células mesenquimales troncales adultas alogénicas de médula ósea no expandidas----1件: 274
34Células mesenquimales troncales adultas alogénicas de médula ósea no expandidas(ref cruzada PEI nº 12-088)----1件: 274
35Denosumab1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬8件: 46, 50, 70, 93, 95, 96, 274, 299
36Denosumab - - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬1件: 274
37Denosumab - Immunoglobulin G2 Human Monoclonal Antibody to RANK Ligand1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬1件: 274
38Denusomab----1件: 274
39Disodium Pamidronate 15mg (15mg strength)1件: Pamidronic acid1件: D07281 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
40Evenity1件: Romosozumab1件: D10156 1件: SOST 💬2件: Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬1件: 274
41Evenity 105mg1件: Romosozumab1件: D10156 1件: SOST 💬2件: Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬1件: 274
42Expanded human first trimester fetal liver-derived mesenchymal stem cells----1件: 274
43Forsteo1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬3件: 70, 235, 274
44Fultium-D3 800IU capsules----1件: 274
45GENOTROPIN*1TBF 5,3MG (16UI)1件: Somatotropin---1件: 274
46H05AA02----1件: 274
47High-dose vitamin D (2000 IU per day)1件: Vitamin D---1件: 274
48Humatrope----2件: 78, 274
49Ibandronic acid1件: Ibandronate---1件: 274
50Mesenchymal stem cells----11件: 2, 6, 13, 20, 49, 51, 60, 96, 222, 274, 299
51Mesenchymal Stromal Cells1件: Human Umbilical Cord Mesenchymal Stem Cells---10件: 2, 36, 49, 51, 60, 96, 97, 107, 274, 284
52NERIXIA*INFUS IV CONC 2F 100MG----1件: 274
53Optinate 5 mg filmcoated tablets----1件: 274
54Pamidronate1件: Pamidronic acid1件: D07281 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 270, 271, 274
55Pamidronate (Aredia)1件: Pamidronic acid1件: D07281 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
56PLASMASAFE----1件: 274
57PLASMASAFE - SOLUZIONE PER INFUSIONE 1 SACCA DA 200 ML----1件: 274
58Prolia1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬1件: 274
59REF CRUZADA PEI Nº 12-088----1件: 274
60Risedronate1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬7件: 46, 50, 66, 96, 107, 113, 274
61Risedronate Oral Tablet1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
62RISEDRONATE SODIUM1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬4件: 50, 107, 113, 274
63Risedronate sodium (Actonel)1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
64Risedronate sodium 2.5mg1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
65Risedronate sodium 5mg1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
66Risedronato sódico 2.5mg----1件: 274
67Risedronato sódico 5mg----1件: 274
68Risedronic acid1件: Risedronic acid1件: D08484 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 93, 95, 274
69RITUXIMAB1件: Rituximab1件: D02994 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬48件: 11, 13, 14, 19, 26, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331
70ROMOSOZUMAB1件: Romosozumab1件: D10156 1件: SOST 💬2件: Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬1件: 274
71SAR439459----1件: 274
72SETRUSUMAB1件: Setrusumab---1件: 274
73Somatropin1件: Somatotropin---19件: 2, 3, 19, 46, 65, 74, 75, 78, 96, 107, 113, 187, 193, 195, 238, 265, 274, 276, 299
74Standard-dose vitamin D (400IU per day)1件: Vitamin D---1件: 274
75Teriparatide1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬6件: 46, 68, 70, 71, 235, 274
76Teriparatide (FORTEO)1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 274
77Teriparatide Pen Injector1件: Teriparatide1件: D06078 1件: PTH1R 💬3件: Endocrine and other factor-regulated calcium reabsorption, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action 💬1件: 274
78Tranexamic acid1件: Tranexamic acid1件: D01136 1件: PLG 💬4件: Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬7件: 46, 70, 215, 227, 274, 288, 299
79UX143, BPS804----1件: 274
80VARI----2件: 62, 274
81Vitamin D1件: Vitamin D---20件: 13, 19, 41, 43, 44, 46, 49, 50, 68, 93, 95, 96, 97, 179, 222, 228, 235, 274, 298, 299
82Vitamina D e calcio1件: Calcium---1件: 274
83XGEVA1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬1件: 274
84XGEVA - 120 MG - SOLUZIONE INIETTABILE - USO SOTTOCUTANEO - FLACONCINO (VETRO) - 1.7 ML 4 FLACONCINI1件: Denosumab1件: D03684 1件: TNFSF11 💬8件: Breast cancer, Chemical carcinogenesis - receptor activation, Cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, Osteoclast differentiation, Parathyroid hormone synthesis, secretion and action, Prolactin signaling pathway, Rheumatoid arthritis 💬1件: 274
85ZOL446----1件: 274
86Zoledronic acid1件: Zoledronic acid2件: D01968 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬12件: 5, 6, 13, 17, 46, 93, 95, 96, 270, 274, 299, 333
87Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion, generic medicinal product1件: Zoledronic acid2件: D01968 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
88Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion, generic medicinal product.1件: Zoledronic acid2件: D01968 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
89Zoledronic Acid Kern Pharma 4 mg/100 mL solution for infusion,generic medicinal product1件: Zoledronic acid2件: D01968 ,
D08689 		1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬1件: 274
90Zometa----1件: 274
91Ácido risedrónico----1件: 274