Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1100 mg ELX (VX-445) / 50 mg TEZ / 75 mg IVA FDC----1件: 299
2100 mg ELX /50 mg TEZ /75 mg IVA FDC----1件: 299
3100 mg ELX/50 mg TEZ /75 mg IVA FDC----1件: 299
4100 mg ELX/50 mg TEZ/75 mg IVA fixed dose combination----1件: 299
5100 mg VX-445 /50 mg TEZ/75 mg IVA FDC----1件: 299
6100 mg VX-445/50 mg TEZ /75 mg IVA FDC----1件: 299
7100-mg ELX (VX-445) / 50-mg TEZ / 75-mg IVA FDC----1件: 299
8100-mg ELX (VX-455) / 50-mg TEZ / 75-mg IVA FDC----1件: 299
9100-mg ELX / 50-mg TEZ / 75 -mg IVA FDC----1件: 299
10100-mg VX-445 / 50-mg TEZ / 75- mg IVA FDC----1件: 299
11100-mg VX-445 / 50-mg TEZ / 75-mg IVA FDC----1件: 299
12100-mg VX-445 /50-mg TEZ/75-mg----1件: 299
13100-mg VX-445/50-mg TEZ/75-mg IVA FDC----1件: 299
14100g ELX / 50mg TEZ / 75mg IVA----1件: 299
15100mg ELX/50mg TEZ /75mg IVA----1件: 299
16100mg VX-445/50mg TEZ /75mg IVA FDC----1件: 299
1756/104/75-C----1件: 50
1875----1件: 6
1975 mg Ontamalimab1件: Ontamalimab---2件: 96, 97
2075-mg IVACAFTOR1件: Ivacaftor1件: D09916 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
21750 mg metformin and 7.5 g L-citrulline daily p.o.2件: Citrulline,
Metformin (Synonym: Metformin ER 750 mg)		1件: D04966 2件: PRKAA1,
PRKAA2 💬		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬1件: 113
22750mg mesalazine pellets1件: Mesalazine1件: D00377 --1件: 97
2375mg CXA-101件: CXA-10---1件: 86
2475mg SHP647 (PF-00547659)----1件: 97
25AIN457, 75 mg----1件: 271
26Atacicept 75 mg1件: Atacicept1件: D09704 2件: TNFSF13,
TNFSF13B 💬		4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬3件: 13, 49, 66
27Atacicept 75 milligram (mg)1件: Atacicept1件: D09704 2件: TNFSF13,
TNFSF13B 💬		4件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬1件: 49
28AZLI 75 mg three times a day (TID)----1件: 299
29AZLI 75 mg three times daily (TID)----1件: 299
30AZLI 75 mg two times a day (BID)/ three times a day (TID)----1件: 299
31AZLI 75 mg two times a day (BID)/three times a day (TID)----1件: 299
32Betaloc ZOK 25, 23,75 mg----1件: 113
33BMS-986004 75 mg IV----1件: 63
34Catapresan 75----1件: 78
35Catapresan 75, Tabletten----1件: 65
36Cayston 75 mg Pulver und Lösungsmittel zur Herstellung einer Lösung für einen Vernebler1件: Aztreonam1件: D00240 --1件: 299
37CAYSTON aztreonam 75 mg powder and solvent for nebuliser solution1件: Aztreonam1件: D00240 --1件: 299
38Certican 0,75mg1件: Everolimus1件: D02714 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬1件: 228
39Certican 0,75mg Tabletten1件: Everolimus1件: D02714 1件: MTOR 💬51件: AMPK signaling pathway, Acute myeloid leukemia, Adipocytokine signaling pathway, Alzheimer disease, Amyotrophic lateral sclerosis, Apelin signaling pathway, Autophagy - animal, Autophagy - other, Breast cancer, Cellular senescence, Central carbon metabolism in cancer, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Diabetic cardiomyopathy, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, ErbB signaling pathway, Gastric cancer, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Huntington disease, Insulin resistance, Insulin signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Longevity regulating pathway, Longevity regulating pathway - multiple species, MicroRNAs in cancer, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Shigellosis, Spinocerebellar ataxia, Th17 cell differentiation, Thermogenesis, Thyroid hormone signaling pathway, Type II diabetes mellitus, mTOR signaling pathway 💬1件: 228
40Cohort 2 0.75g----1件: 240
41Colistimethate 75 mg inhaled two times daily1件: Colistimethate---1件: 299
42Continuous oxygen
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--1件: 90
43CVL-751----1件: 6
44Depot leuprolide acetate 3.75 mg2件: Acetate,
Leuprolide		---1件: 51
45Dulaglutide 0.75Mg/0.5Ml Inj Pen1件: Dulaglutide1件: D09889 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 299
46Ebetrex 15 mg = 0,75 ml, oplossing voor injectie in voorgevulde injectiespuit 20 mg/ml----1件: 96
47Efexor XL 75 mg----1件: 46
48Efexor XL 75 mg (venlafaxine)1件: Venlafaxine1件: D08670 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬1件: 46
49Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 ,
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
50Helium / oxygen mixed gas inhalation therapy
(Synonym: OXYGEN/HELIUM 25/75)		2件: Helium,
Oxygen (Synonym: Oxygen/Helium 25/75)		2件: D00003 (Name: OXYGEN/HELIUM 25/75),
D04420 		--1件: 330
51IncobotulinumtoxinA (75 Units)1件: Botulinum toxin type A1件: D00783 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬1件: 6
52Inhaled nitric oxide 75 mcg/kg IBW/hr1件: Nitric Oxide1件: D00074 --2件: 85, 86
53INM-755----1件: 36
54INM-755 (cannabinol) cream1件: Cannabinol---1件: 36
55Irbesartan tablets (NDA 020 757)1件: Irbesartan1件: D00523 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 66
56Ivacaftor 25 mg/75 mg1件: Ivacaftor1件: D09916 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
57Ivacaftor 75 mg1件: Ivacaftor1件: D09916 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
58Ivacaftor 75 mg/150 mg1件: Ivacaftor1件: D09916 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
59IVACAFTOR 75mg1件: Ivacaftor1件: D09916 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
60Jaktinib Dihydrochloride Monohydrate 50mg BID and Mimic tablets of jakitinib hydrochloride 75mg BID and Acetylcysteine Effervescent Tablets1件: Acetylcysteine1件: D00221 --1件: 85
61Jaktinib Dihydrochloride Monohydrate 75mg BID and Mimic tablets of jakitinib hydrochloride 50mg BID and Acetylcysteine Effervescent Tablets1件: Acetylcysteine1件: D00221 --1件: 85
62JNJ-54781532 75 mg once daily----1件: 97
63JNJ-54781532 75 mg twice daily----1件: 97
64Leuprorelin Acetate 3.75mg Injection2件: Acetate,
Leuprolide		---1件: 76
65Levodopa 75 mg A CAP1件: Levodopa1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
66LIQ861 75 µg----1件: 86
67Luphere depot 3.75mg(Leuprolide acetate 3.75mg)2件: Acetate,
Leuprolide		---1件: 76
68M2951 75 mg QD----1件: 46
69Macitentan 75 mg1件: Macitentan1件: D10135 2件: EDNRA,
EDNRB 💬		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
70Medical Air vs Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		2件: Medical air,
Oxygen (Synonym: Oxygen/Helium 25/75)		1件: D00003 (Name: OXYGEN/HELIUM 25/75)--1件: 193
71Medical Grade Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--1件: 299
72MetoHEXAL® Succ ® 23,75 mg Retardtabletten----1件: 113
73Nitric Oxide plus Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		2件: Nitric Oxide,
Oxygen (Synonym: Oxygen/Helium 25/75)		2件: D00003 (Name: OXYGEN/HELIUM 25/75),
D00074 		--1件: 86
74Oral Glucose Tolerance test (75g 2-hour)1件: Dextrose, unspecified form (Synonym: 75gm Glucose Tolerance Drink)---1件: 299
75Over-encapsulated 75 mg Irbesartan Tablets1件: Irbesartan1件: D00523 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 222
76Oxygen
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--13件: 6, 49, 70, 85, 86, 88, 90, 96, 168, 193, 271, 299, 330
77Oxygen 40 %
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--1件: 85
78Oxygen supplementation
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--1件: 86
79Oxygen, liquid
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--2件: 86, 88
80Oxygen-15 Water
(Synonym: OXYGEN/HELIUM 25/75)		2件: Oxygen (Synonym: Oxygen/Helium 25/75),
Water (Synonym: GFA First Aid 75 Person Metal Case)		2件: D00001 ,
D00003 (Name: OXYGEN/HELIUM 25/75)		--1件: 6
81P2B001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),2件: Pramipexole,
Rasagiline		3件: D05575 ,
D08469 ,
D10829 		4件: DRD2,
DRD3,
DRD4,
MAOB 💬		18件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬1件: 6
82P2B001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),2件: Pramipexole,
Rasagiline		3件: D05575 ,
D08469 ,
D10829 		4件: DRD2,
DRD3,
DRD4,
MAOB 💬		18件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway 💬1件: 6
83P38 Inhibitor (4) 75mg----1件: 46
84Perfluorinated gas/oxygen mixture
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--1件: 299
85Pregabalin 75mg1件: Pregabalin (Synonym: Pregabalin-75)1件: D02716 4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬1件: 70
86RANEXA - 750 MG - COMPRESSA A RILASCIO PROLUNGATO- USO ORALE - BLISTER (PVC/PVDC/ALLUMINIO) 60 COMPRESSE1件: Ranolazine1件: D05700 --1件: 58
87RANEXA*60CPR 750MG R.P.1件: Ranolazine1件: D05700 --1件: 58
88Ranolazine 750 mg PR tablets1件: Ranolazine1件: D05700 --1件: 58
89Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die1件: Ranolazine1件: D05700 --1件: 58
90Revolade 75 mg1件: Eltrombopag---1件: 60
91RhuDex 25 mg (31.75 mg RhuDex choline salt) granules1件: Choline (Synonym: Mega-vim 75 With Beta-carotene - Tablets)1件: D07690 --1件: 93
92RO 487-7533----1件: 46
93Ro 487-7533/F01----3件: 46, 107, 271
94Ro 487-7533/F10----2件: 46, 107
95Ro 487-7533/F10-02----1件: 46
96Ro 487-7533/F10-04----4件: 41, 46, 51, 107
97Ro 491-7523/F18----1件: 206
98Ro 491-7523/F19----1件: 206
99Ro487-7533----1件: 46
100RO487-7533/F01-F05----1件: 46
101RO487-7533/F10-04----2件: 46, 51
102Secukinumab (75 mg)1件: Secukinumab1件: D09967 1件: IL17A 💬6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬1件: 271
103Secukinumab 75 mg/0.5 ml Solution for injection1件: Secukinumab1件: D09967 1件: IL17A 💬6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬1件: 271
104Standard analgesia use [Oxygen]
(Synonym: OXYGEN/HELIUM 25/75)		1件: Oxygen (Synonym: Oxygen/Helium 25/75)1件: D00003 (Name: OXYGEN/HELIUM 25/75)--1件: 70
105SUSPENSION CONTAINING 7500 EMBRYONATED VIABLE TRICHURIS SUIS OVA/15ML----1件: 97
106Suspension containing 7500 embryonated, viable Trichuris suis ova (TSO)/15ml----1件: 96
107Suspension of 7500 embryonated, viable TSO/15ml----1件: 96
108TAK-755----1件: 64
109TAK-755 or BAX930 or SHP655----1件: 64
110TAK-755 orBAX930 or SHP655----1件: 64
111Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere1件: Dulaglutide1件: D09889 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 13
112Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere.1件: Dulaglutide1件: D09889 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 13
113TSO 7500----1件: 96
114Vamorolone 0.75 mg/day/day1件: Vamorolone1件: D11000 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 113
115Vamorolone 0.75 mg/kg/day1件: Vamorolone1件: D11000 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 113
116Veltuzumab solution 75mg/ml1件: Veltuzumab1件: D09031 1件: MS4A1 💬1件: Hematopoietic cell lineage 💬1件: 46
117VX-661/ivacaftor 50 mg/ 75 mg1件: Ivacaftor1件: D09916 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299