Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1150-mg IVACAFTOR1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
2150mg IVACAFTOR1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
375-mg IVACAFTOR1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
4CF patients with a G551D mutation and treated with Ivacaftor1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
5Deuterated Ivacaftor1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
6Elexacaftor / Ivacaftor / Tezacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 (Name: Ivacaftor),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
7Elexacaftor 100 MG / Ivacaftor 75 MG / Tezacaftor 50 MG, 2 tablets each morning + Ivacaftor 150 mg one tablet each evening3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 (Name: Ivacaftor),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
8Elexacaftor-tezacaftor-ivacaftor exposure3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 (Name: Ivacaftor),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
9Elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 (Name: Ivacaftor),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
10IVACAFTOR1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
11Ivacaftor (proposed INN)1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
12Ivacaftor 125mg tablet1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
13Ivacaftor 150 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
14Ivacaftor 150 mg or 250 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
15Ivacaftor 25 mg/75 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
16IVACAFTOR 59,5mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
17IVACAFTOR 59.5mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
18Ivacaftor 75 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
19Ivacaftor 75 mg/150 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
20IVACAFTOR 75mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
21Ivacaftor Exposed1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
22Ivacaftor or elexacaftor/tezacaftor/ivacaftor3件: Elexacaftor,
Ivacaftor,
Tezacaftor		3件: D09916 (Name: Ivacaftor),
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
23Ivacaftor+lumacaftor2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
24Ivacaftor/Ataluren2件: Ataluren,
Ivacaftor		2件: D09323 ,
D09916 (Name: Ivacaftor)		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
25Ivacaftor/Kalydeco1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
26Ivacaftor/Trikafta1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
27Lumacaftor / ivacaftor2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
28Lumacaftor plus Ivacaftor2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
29Lumacaftor Plus Ivacaftor Combination2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
30Lumacaftor, Ivacaftor Drug Combination2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
31Lumacaftor-ivacaftor2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
32Lumacaftor-Ivacaftor treatment2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
33Lumacaftor/Ivacaftor2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
34Lumacaftor/ivacaftor 100mg/125mg tablets2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
35Lumacaftor/ivacaftor 200mg/125mg2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
36Lumacaftor/ivacaftor 200mg/125mg tablets2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
37Lumacaftor/ivacaftor 200mg/83mg tablet2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
38Orkambi: contains lumacaftor and ivacaftor2件: Ivacaftor,
Lumacaftor		2件: D09916 (Name: Ivacaftor),
D10134 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
39Tezacaftor/Ivacaftor2件: Ivacaftor,
Tezacaftor		2件: D09916 (Name: Ivacaftor),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
40Tezacaftor/Ivacaftor + Ivacaftor2件: Ivacaftor,
Tezacaftor		2件: D09916 (Name: Ivacaftor),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
41Tezacaftor/Ivacaftor 100mg/150mg2件: Ivacaftor,
Tezacaftor		2件: D09916 (Name: Ivacaftor),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
42Tezacaftor/Ivacaftor/100mg/150mg2件: Ivacaftor,
Tezacaftor		2件: D09916 (Name: Ivacaftor),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
43Treatment with cystic fibrosis transmembrane regulator (CFTR) modualtors Ivacaftor, Lumacaftor-Ivacaftor, Tezacaftor-Ivacaftor, Elexacaftor-Tezacaftor-Ivacaftor4件: Elexacaftor,
Ivacaftor,
Lumacaftor,
Tezacaftor		4件: D09916 (Name: Ivacaftor),
D10134 ,
D11041 ,
D11507 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
44VX-659/Tezacaftor/Ivacaftor3件: Ivacaftor,
Tezacaftor,
VX-659		2件: D09916 (Name: Ivacaftor),
D11041 		1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
45VX-661 Plus Ivacaftor Combination1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
46VX-661/Ivacaftor1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
47VX-661/ivacaftor (VX-770) 100mg/150 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
48VX-661/ivacaftor 100 mg/ 150 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
49VX-661/ivacaftor 100mg/150 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
50VX-661/ivacaftor 100mg/150mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
51VX-661/ivacaftor 50 mg/ 75 mg1件: Ivacaftor1件: D09916 (Name: Ivacaftor)1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299