KEGG DRUG

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No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Amiodarone	1件: Amiodarone	1件: D02910 (Name: Amiodarone)	16件: ADRA1A, ADRA1B, ADRA1D, ADRB1, KCND3, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬	2件: 28, 127
2	Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhithmias)	1件: Amiodarone	1件: D02910 (Name: Amiodarone)	16件: ADRA1A, ADRA1B, ADRA1D, ADRB1, KCND3, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬	1件: 28
3	Diuretics (plus antiarrhythmic drugs, i.e. amiodarone, in case of complex ventricular arrhythmias) plus EGCG	2件: Amiodarone, Epigallocatechin gallate	1件: D02910 (Name: Amiodarone)	16件: ADRA1A, ADRA1B, ADRA1D, ADRB1, KCND3, KCNJ11, KCNJ12, KCNJ3, KCNJ5, KCNJ8, KCNQ1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬	32件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Insulin secretion, Morphine addiction, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬	1件: 28