Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acthar high dose (80 U)1件: Corticotropin1件: Corticotropin 💬 1件: MC2R 💬 5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 49 💬
2Administration of a high dose of desipramine1件: Desipramine1件: Desipramine 💬 2件: SLC6A2,
SLC6A4 💬 		2件: Serotonergic synapse, Synaptic vesicle cycle 💬1件: 156 💬
3Ambrisentan - high dose1件: Ambrisentan1件: Ambrisentan 💬 1件: EDNRA 💬 7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
4AXO-AAV-GM2 High Dose----1件: 19 💬
5BI 655064 high dose----1件: 46 💬
6BIIL 284 BS high dose----1件: 46 💬
7BIIL 284 BS, high dose----1件: 299 💬
8BIIL 284 BS, high dose, adult patients----1件: 299 💬
9BIIL 284 BS, high dose, pediatric patients----1件: 299 💬
10BIRB 796 BS, high dose----1件: 46 💬
11BLI-1300 high dose----1件: 96 💬
12Brazikumab high dose1件: Brazikumab1件: Brazikumab 💬 1件: IL23A 💬 9件: C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬1件: 96 💬
13CHF10067 high dose----1件: 85 💬
14Clobazam High Dose1件: Clobazam1件: Clobazam 💬 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 144 💬
15CPL500036 - high dose----1件: 6 💬
16CVT-301 High Dose----1件: 6 💬
17DNS-7801 (high dose)----1件: 6 💬
18Elamipretide (high dose)1件: Elamipretide1件: Elamipretide 💬 --1件: 21 💬
19Enpatoran high dose----1件: 49 💬
20EUR-1008 (APT-1008) High Dose----1件: 298 💬
21Fentanyl (High Dose)1件: Fentanyl1件: Fentanyl 💬 1件: OPRM1 💬 3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 215 💬
22GTX-102 high dose fast Period 1 and Period 21件: GTX-102---1件: 65 💬
23High dose----1件: 97 💬
24High dose AFFITOPE® PD03A + Adjuvant----1件: 6 💬
25High dose ANAVEX2-73----1件: 6 💬
26High Dose Aspirin (1300 mg/day)1件: Acetylsalicylic acid1件: Aspirin 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 13 💬
27High dose BIBF 1120 twice daily----1件: 85 💬
28High Dose Budesonide1件: Budesonide1件: Budesonide 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 97 💬
29High dose budesonide suspension1件: Budesonide1件: Budesonide 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 98 💬
30High dose budesonide tablet1件: Budesonide1件: Budesonide 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 98 💬
31High dose Dexamethasone pulses1件: Dexamethasone1件: Dexamethasone 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 63 💬
32High dose lactulose1件: Lactulose1件: Lactulose 💬 --1件: 291 💬
33High dose levodopa1件: Levodopa1件: Levodopa 💬 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬 		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6 💬
34High Dose LX2006----1件: 18 💬
35High Dose Mesenchymal Stem Cells (MSCs)----1件: 49 💬
36High Dose MT-1303----1件: 97 💬
37High Dose MYOBLOC1件: Botulinum toxin type B1件: Rimabotulinumtoxin B 💬 1件: SNAP25 💬 2件: Insulin secretion, Synaptic vesicle cycle 💬1件: 13 💬
38High dose of BIIL 284 BS tablets----1件: 46 💬
39High dose of budesonide1件: Budesonide1件: Budesonide 💬 1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬1件: 299 💬
40High dose ORTD-1----1件: 46 💬
41High dose TSO----1件: 96 💬
42High dose vehicle control----1件: 46 💬
43High Dose-VIS649----1件: 66 💬
44High doses of Thiamine y Biotin2件: Biotin,
Thiamine		2件: Biotin ,
Thiamine 💬 		--1件: 8 💬
45HMPL-004 high dose----1件: 97 💬
46IgPro20 (high dose)----1件: 14 💬
47Imsidolimab high dose1件: Imsidolimab1件: Imsidolimab 💬 1件: IL1RL2 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 37 💬
48KPS-0373, High dose----1件: 18 💬
49KW-6356 High Dose1件: KW-6356---1件: 6 💬
50LiRIS low dose and LiRIS high dose----1件: 226 💬
51LX3305 high dose----1件: 46 💬
52M5049 high dose----2件: 49, 50 💬
53MEDI7183 high dose----1件: 97 💬
54MMX Mesalamine/Mesalazine (High Dose)1件: Mesalazine1件: Mesalamine 💬 --1件: 97 💬
55MT-1303 High dose----1件: 49 💬
56MT-7117 High Dose----1件: 254 💬
57MultiStem high dose1件: MultiStem---1件: 97 💬
58OCU400 High Dose----1件: 90 💬
59Orelabrutinib (High Dose)1件: Orelabrutinib1件: Orelabrutinib 💬 1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬1件: 49 💬
60Part 2 Adult Alogabat High Dose (aged 15-17)----1件: 201 💬
61PF-06649751 high dose (15 mg QD)1件: Tavapadon1件: Tavapadon 💬 2件: DRD1,
DRD5 💬 		10件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬1件: 6 💬
62PHA-022121 high dose----1件: 65 💬
63PXT3003 High Dose----1件: 10 💬
64Ravicti high dose1件: Glycerol phenylbutyrate1件: Glycerol phenylbutyrate 💬 --1件: 299 💬
65SA001 High dose----1件: 53 💬
66SC0062 high dose----1件: 66 💬
67SEN0014196 (High Dose)----1件: 8 💬
68TAS5315 high dose----1件: 46 💬
69Vitamin D3 - high dose1件: Cholecalciferol1件: Cholecalciferol 💬 1件: VDR 💬 5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 6 💬
70YRA-1909 high dose----1件: 46 💬