Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Acthar high dose (80 U)1件: Corticotropin1件: D00146 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 49
2Administration of a high dose of desipramine1件: Desipramine1件: D07791 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬1件: 156
3Ambrisentan - high dose1件: Ambrisentan1件: D07077 1件: EDNRA 💬7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86
4AXO-AAV-GM2 High Dose----1件: 19
5BI 655064 high dose----1件: 46
6BIIL 284 BS high dose----1件: 46
7BIIL 284 BS, high dose----1件: 299
8BIIL 284 BS, high dose, adult patients----1件: 299
9BIIL 284 BS, high dose, pediatric patients----1件: 299
10BIRB 796 BS, high dose----1件: 46
11BLI-1300 high dose----1件: 96
12Brazikumab high dose1件: Brazikumab1件: D10912 1件: IL23A 💬9件: C-type lectin receptor signaling pathway, Cytokine-cytokine receptor interaction, Inflammatory bowel disease, JAK-STAT signaling pathway, Pathways in cancer, Pertussis, Rheumatoid arthritis, Th17 cell differentiation, Tuberculosis 💬1件: 96
13CHF10067 high dose----1件: 85
14Clobazam High Dose1件: Clobazam1件: D01253 16件: GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		7件: GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬1件: 144
15CPL500036 - high dose----1件: 6
16CVT-301 High Dose----1件: 6
17DNS-7801 (high dose)----1件: 6
18Elamipretide (high dose)1件: Elamipretide1件: D10925 --1件: 21
19Enpatoran high dose----1件: 49
20EUR-1008 (APT-1008) High Dose----1件: 298
21Fentanyl (High Dose)1件: Fentanyl1件: D00320 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬1件: 215
22GTX-102 high dose fast Period 1 and Period 21件: GTX-102---1件: 65
23High dose----1件: 97
24High dose AFFITOPE® PD03A + Adjuvant----1件: 6
25High dose ANAVEX2-73----1件: 6
26High Dose Aspirin (1300 mg/day)1件: Acetylsalicylic acid1件: D00109 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 13
27High dose BIBF 1120 twice daily----1件: 85
28High Dose Budesonide1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 97
29High dose budesonide suspension1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 98
30High dose budesonide tablet1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 98
31High dose Dexamethasone pulses1件: Dexamethasone1件: D00292 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 63
32High dose lactulose1件: Lactulose1件: D00352 --1件: 291
33High dose levodopa1件: Levodopa1件: D00059 5件: DRD1,
DRD2,
DRD3,
DRD4,
DRD5 💬		11件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 6
34High Dose LX2006----1件: 18
35High Dose Mesenchymal Stem Cells (MSCs)----1件: 49
36High Dose MT-1303----1件: 97
37High Dose MYOBLOC1件: Botulinum toxin type B1件: D02735 1件: SNAP25 💬2件: Insulin secretion, Synaptic vesicle cycle 💬1件: 13
38High dose of BIIL 284 BS tablets----1件: 46
39High dose of budesonide1件: Budesonide1件: D00246 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬1件: 299
40High dose ORTD-1----1件: 46
41High dose TSO----1件: 96
42High dose vehicle control----1件: 46
43High Dose-VIS649----1件: 66
44High doses of Thiamine y Biotin2件: Biotin,
Thiamine		2件: D00029 ,
D08580 		--1件: 8
45HMPL-004 high dose----1件: 97
46IgPro20 (high dose)----1件: 14
47Imsidolimab high dose1件: Imsidolimab1件: D11892 1件: IL1RL2 💬1件: Cytokine-cytokine receptor interaction 💬1件: 37
48KPS-0373, High dose----1件: 18
49KW-6356 High Dose1件: KW-6356---1件: 6
50LiRIS low dose and LiRIS high dose----1件: 226
51LX3305 high dose----1件: 46
52M5049 high dose----2件: 49, 50
53MEDI7183 high dose----1件: 97
54MMX Mesalamine/Mesalazine (High Dose)1件: Mesalazine1件: D00377 --1件: 97
55MT-1303 High dose----1件: 49
56MT-7117 High Dose----1件: 254
57MultiStem high dose1件: MultiStem---1件: 97
58OCU400 High Dose----1件: 90
59Orelabrutinib (High Dose)1件: Orelabrutinib1件: D12160 1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬1件: 49
60Part 2 Adult Alogabat High Dose (aged 15-17)----1件: 201
61PF-06649751 high dose (15 mg QD)1件: Tavapadon1件: D11431 2件: DRD1,
DRD5 💬		10件: Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, cAMP signaling pathway 💬1件: 6
62PHA-022121 high dose----1件: 65
63PXT3003 High Dose----1件: 10
64Ravicti high dose1件: Glycerol phenylbutyrate1件: D10127 --1件: 299
65SA001 High dose----1件: 53
66SC0062 high dose----1件: 66
67SEN0014196 (High Dose)----1件: 8
68TAS5315 high dose----1件: 46
69Vitamin D3 - high dose1件: Cholecalciferol1件: D00188 1件: VDR 💬5件: Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬1件: 6
70YRA-1909 high dose----1件: 46